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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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1.9
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  • Comparison between Lipofectamine RNAiMAX and GenMute transfection agents in two cellular models of human hepatoma

    Clarissa Berardo, Veronica Siciliano, Laura G. Di Pasqua, Plinio Richelmi, Mariapia Vairetti, Andrea Ferrigno
    06-08-2019
    https://doi.org/10.4081/ejh.2019.3048
    3109
    PDF: 1836
    HTML: 36
  • Inhibition of APLN suppresses cell proliferation and migration and promotes cell apoptosis in esophageal cancer cells in vitro, through activating PI3K/mTOR signaling pathway

    Yuhan Wang, Gang Wang, Xiaojun Liu, Dong Yun, Qing Cui, Xiaoting Wu, Wenfeng Lu, Xiwen Yang, Ming Zhang
    03-08-2022
    https://doi.org/10.4081/ejh.2022.3336
    1568
    PDF: 769
    HTML: 49
  • Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

    Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang
    01-08-2023
    https://doi.org/10.4081/ejh.2023.3784
    2050
    PDF: 884
    HTML: 23
  • Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

    Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3766
    2071
    PDF: 1294
    HTML: 21
  • Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells via regulation of miR-1234/TP53I11 axis

    Jinbi Xie, Yong Ning, Lihang Zhang, Yuan Lin, Runsheng Guo, Shanjuan Wang
    03-10-2022
    https://doi.org/10.4081/ejh.2022.3477
    2029
    PDF: 663
    HTML: 43
  • Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

    Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye
    30-09-2021
    https://doi.org/10.4081/ejh.2021.3224
    3526
    PDF: 1910
    HTML: 41
  • DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

    Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu
    03-05-2017
    https://doi.org/10.4081/ejh.2017.2775
    2710
    PDF: 1032
    HTML: 184
  • Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

    Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4533
    395
    PDF: 238
    HTML: 13
  • Effects of the lncRNA ENST00000623984 on colon cancer and the biological characteristics of colon cancer cells

    Zhi-bao Liu, Jing-hua Zhang, Jing-hua Gao, Jian Shi
    12-07-2021
    https://doi.org/10.4081/ejh.2021.3215
    2207
    PDF: 569
    HTML: 31
  • Effect of CDX2 on proliferation, invasion, migration, and apoptosis of duodenal cancer cells

    Jun Pan, Yi Zhao, Yu Zhang, Yuhe Zhou, Fengxuan Zhang, Yitian Chen, Xiaoyuan Chu
    24-04-2025
    https://doi.org/10.4081/ejh.2025.4203
    755
    PDF: 328
    HTML: 53
  • Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

    Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li
    22-07-2024
    https://doi.org/10.4081/ejh.2024.4048
    2381
    PDF: 1326
    HTML: 22
  • MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9

    Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3275
    2039
    PDF: 811
    Supplementary: 153
    HTML: 37
  • Continuous cyclic mechanical tension increases ank expression in endplate chondrocytes through the TGF-β1 and p38 pathway

    H. Xu, X. Zhang, H. Wang, Y. Zhang, Y. Shi, X. Zhang
    e28
    25-09-2013
    https://doi.org/10.4081/ejh.2013.e28
    2388
    PDF: 672
    HTML: 221
  • Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

    Jiapei Lv, Wang Yanting, Shan Wei
    08-11-2023
    https://doi.org/10.4081/ejh.2023.3867
    2051
    PDF: 1012
    HTML: 53
  • An emerging potential therapeutic target for osteoporosis: LncRNA H19/miR-29a-3p axis

    Ziqi Li, Zhinan Hong, Yuesheng Zheng, Yongwei Dong, Wei He, Yingjia Yuan, Junbiao Guo
    06-11-2020
    https://doi.org/10.4081/ejh.2020.3155
    1594
    PDF: 740
    HTML: 13
  • Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

    Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang
    29-04-2024
    https://doi.org/10.4081/ejh.2024.4019
    1919
    PDF: 713
    HTML: 28
  • Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

    Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi
    22-05-2024
    https://doi.org/10.4081/ejh.2024.4033
    1219
    PDF: 525
    HTML: 19
  • MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells

    J. Zhang, J. Luo, J. Ni, L. Tang, H.P. Zhang, L. Zhang, J.F. Xu, D. Zheng
    18-02-2014
    https://doi.org/10.4081/ejh.2014.2262
    3489
    PDF: 1034
    HTML: 330
  • Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

    Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng
    03-09-2021
    https://doi.org/10.4081/ejh.2021.3264
    1990
    PDF: 733
    Supplementary: 149
    HTML: 31
  • SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

    Yiyu Qin, Jian Li, Hongchao Han, Yongliang Zheng, Haiming Lei, Yang Zhou, Hongyan Wu, Guozhe Zhang, Xiang Chen, Zhengping Chen
    28-12-2023
    https://doi.org/10.4081/ejh.2023.3899
    1118
    PDF: 330
    HTML: 10
  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    1260
    PDF: 606
    HTML: 22
  • Characterization of the role of RILP in cell migration

    Azzurra Margiotta, Cinzia Progida, Oddmund Bakke, Cecilia Bucci
    31-05-2017
    https://doi.org/10.4081/ejh.2017.2783
    2544
    PDF: 971
    Supplementary: 251
    Movie 1: 346
    Movie 2: 394
    HTML: 108
  • Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway

    Li Chu, Suhong Ma, Zhiwei Chen, Wenfu Cao
    01-04-2021
    https://doi.org/10.4081/ejh.2021.3198
    1816
    PDF: 962
    HTML: 25
  • Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

    Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li
    25-10-2022
    https://doi.org/10.4081/ejh.2022.3529
    1768
    PDF: 833
    HTML: 38
  • Downregulation of SRPK2 promotes cell cycle arrest though E2F1 in non-small cell lung cancer

    Xin Li, Shaoyu Yang, Minna Zhang, Shuhuan Xie, Zefeng Xie
    11-12-2019
    https://doi.org/10.4081/ejh.2019.3067
    2063
    PDF: 1116
    HTML: 21
  • Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway

    Y. Zhang, J. Wang, X. Cheng, B. Yi, X. Zhang, Q. Li
    13-04-2015
    https://doi.org/10.4081/ejh.2015.2467
    3643
    PDF: 1610
    HTML: 896
  • NOP14 regulates the growth, migration, and invasion of colorectal cancer cells by modulating the NRIP1/GSK-3β/β-catenin signaling pathway

    Xuanjin Zhu, Weilu Jia, Yong Yan, Yong Huang, Bailin Wang
    02-07-2021
    https://doi.org/10.4081/ejh.2021.3246
    2904
    PDF: 780
    HTML: 39
  • Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

    Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan
    13-05-2024
    https://doi.org/10.4081/ejh.2024.3917
    1990
    PDF: 748
    HTML: 50
  • SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

    Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang
    18-05-2026
    https://doi.org/10.4081/ejh.2026.4544
    171
    PDF: 142
    Supplementary: 22
    HTML: 6
  • High glucose inhibits neural differentiation by excessive autophagy via peroxisome proliferator-activated receptor gamma

    Yin Pan, Di Qiu, Shu Chen, Xiaoxue Han, Ruiman Li
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3691
    1307
    PDF: 905
    HTML: 23
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2730
    PDF: 1020
    HTML: 155
  • LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway

    Yong Jiang, Chun-hui Xu, Ying Zhao, Yun-han Ji, Xin-tao Wang, Ying Liu
    16-01-2023
    https://doi.org/10.4081/ejh.2023.3526
    1892
    PDF: 822
    HTML: 64
  • Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

    Jun Lin, Liping Jiang, Kun Guo, Ning Feng
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3528
    2020
    PDF: 1235
    Supplementary: 135
    HTML: 39
  • MiR-130a-5p contributed to the progression of endothelial cell injury by regulating FAS

    Wei Wang, Wenbo Tang, Erbo Shan, Lei Zhang, Shiyuan Chen, Chaowen Yu, Yong Gao
    31-05-2022
    https://doi.org/10.4081/ejh.2022.3342
    1198
    PDF: 738
    HTML: 31
  • The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

    Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3323
    1918
    PDF: 695
    HTML: 34
  • Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

    Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li
    17-05-2023
    https://doi.org/10.4081/ejh.2023.3612
    1417
    PDF: 928
    Supplementary: 100
    HTML: 24
  • Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

    Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang
    26-01-2026
    https://doi.org/10.4081/ejh.2026.4422
    664
    PDF: 387
    Supplementary: 50
    Original gels: 50
    HTML: 16
  • MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

    Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3426
    1489
    PDF: 837
    HTML: 27
  • Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells

    Yinping Zeng, Jiajun Huang, Tingting Duan, Xiaofeng Wang
    28-05-2026
    https://doi.org/10.4081/ejh.2026.4540
    243
    PDF: 181
    HTML: 5
  • The clinical significance of UBE2C gene in progression of renal cell carcinoma

    Zhiping Chen, Lanfeng Wang
    29-03-2021
    https://doi.org/10.4081/ejh.2021.3196
    1888
    PDF: 900
    HTML: 31
  • Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

    Chixian Zhang, Kai Bai, Dexu Li
    14-04-2025
    https://doi.org/10.4081/ejh.2025.4186
    1320
    PDF: 482
    HTML: 32
  • Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study

    M. Di Rosa, M.A. Szychlinska, D. Tibullo, L. Malaguarnera, G. Musumeci
    16-09-2014
    https://doi.org/10.4081/ejh.2014.2423
    2997
    PDF: 1195
    HTML: 1611
  • Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

    J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei
    17-03-2014
    https://doi.org/10.4081/ejh.2014.2263
    3611
    PDF: 1031
    HTML: 592
  • Transient receptor potential canonical 3/5 attenuate endothelial damage-induced neointima formation without affecting endothelial cell proliferation

    Wenjun Zeng, Bei Liu, Lixia Yang, Ruiwei Guo
    19-11-2025
    https://doi.org/10.4081/ejh.2025.4311
    407
    PDF: 204
    HTML: 19
  • Fluorescence and electron microscopy to visualize the intracellular fate of nanoparticles for drug delivery

    M. Costanzo, F. Carton, A. Marengo, G. Berlier, B. Stella, S. Arpicco, M. Malatesta
    14-04-2016
    https://doi.org/10.4081/ejh.2016.2640
    3251
    PDF: 1374
    HTML: 599
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    3051
    PDF: 1174
    Supplementary: 388
    HTML: 1015
  • Atorvastatin reduces calcification in valve interstitial cells via the NF-κB signalling pathway by promoting Atg5-mediated autophagy

    Menghui Chen, Su Liu
    12-04-2024
    https://doi.org/10.4081/ejh.2024.3983
    1332
    PDF: 575
    HTML: 29
  • Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

    Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai
    14-10-2022
    https://doi.org/10.4081/ejh.2022.3510
    1314
    PDF: 681
    HTML: 38
  • RNA therapeutics - Function, design and delivery

    Carlo Alberto Redi
    br7
    17-06-2011
    https://doi.org/10.4081/ejh.2011.br7
    928
    PDF: 448
    HTML: 174
  • Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

    Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno
    15-03-2018
    https://doi.org/10.4081/ejh.2018.2841
    15116
    PDF: 7195
    HTML: 495
  • Assessing the interactions between nanoparticles and biological barriers in vitro: a new challenge for microscopy techniques in nanomedicine

    Flavia Carton, Manuela Malatesta
    24-11-2022
    https://doi.org/10.4081/ejh.2022.3603
    1131
    PDF: 472
    HTML: 22
  • Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

    M. Hinken, S. Halwachs, C. Kneuer, W. Honscha
    e3
    27-01-2011
    https://doi.org/10.4081/ejh.2011.e3
    1885
    PDF: 723
    HTML: 5660
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    311
    PDF: 466
    Supplementary: 36
    HTML: 5
  • PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNFα-CX3CR1 pathway

    Xilei Li, Zhi Ye, Qulian Guo, E Wang, Yundan Pan
    12-03-2021
    https://doi.org/10.4081/ejh.2021.3184
    2161
    PDF: 918
    HTML: 21
  • Activation of Hedgehog pathway by circEEF2/miR-625-5p/TRPM2 axis promotes prostate cancer cell proliferation through mitochondrial stress

    ChenHui Zhu, LiJuan Lin, ChangQing Huang, ZhiHui Wu
    11-11-2024
    https://doi.org/10.4081/ejh.2024.4063
    1607
    PDF: 572
    HTML: 20
  • SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

    Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu
    03-03-2026
    https://doi.org/10.4081/ejh.2026.4530
    497
    PDF: 392
    HTML: 10
  • Seasonal expressions of SPAG11A and androgen receptor in the epididymis of the wild ground squirrels (Citellus dauricus Brandt)

    Wenyang Yu, Ziwen Zhang, Pei Liu, Xiaoying Yang, Haolin Zhang, Zhengrong Yuan, Yingying Han, Qiang Weng
    21-04-2020
    https://doi.org/10.4081/ejh.2020.3111
    1313
    PDF: 627
    HTML: 23
  • Knockdown of RAGE inhibits growth and invasion of gastric cancer cells

    X.C. Xu, X. Abuduhadeer, W.B. Zhang, T. Li, H. Gao, Y.H. Wang
    e36
    18-11-2013
    https://doi.org/10.4081/ejh.2013.e36
    4320
    PDF: 848
    HTML: 268
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    3079
    PDF: 1707
    Video 1: 247
    Video 2: 292
    HTML: 27
  • P32 | BLOCKING CANCER CELL MOVEMENT: THE ROLE OF PAXILLIN AND EZRIN IN CERVICAL TUMOR M. Hałas-Wiśniewska1, W. Arendt1, M. Gagat1,2, M. Izdebska1 | 1Department of Histology and Embryology, Nicolaus Copernicus University in Toruń, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Poland; 2Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4352
    184
  • Ion channels alterations in the forebrain of high-fat diet fed rats

    Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni
    23-11-2021
    https://doi.org/10.4081/ejh.2021.3305
    2221
    PDF: 1112
    HTML: 43
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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