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Comparison between Lipofectamine RNAiMAX and GenMute transfection agents in two cellular models of human hepatoma

Clarissa Berardo, Veronica Siciliano, Laura G. Di Pasqua, Plinio Richelmi, Mariapia Vairetti, Andrea Ferrigno

06-08-2019

https://doi.org/10.4081/ejh.2019.3048

3226

PDF: 1990

HTML: 52
Inhibition of APLN suppresses cell proliferation and migration and promotes cell apoptosis in esophageal cancer cells in vitro, through activating PI3K/mTOR signaling pathway

Yuhan Wang, Gang Wang, Xiaojun Liu, Dong Yun, Qing Cui, Xiaoting Wu, Wenfeng Lu, Xiwen Yang, Ming Zhang

03-08-2022

https://doi.org/10.4081/ejh.2022.3336

1724

PDF: 836

HTML: 51
Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang

01-08-2023

https://doi.org/10.4081/ejh.2023.3784

2227

PDF: 958

HTML: 27
Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao

26-07-2023

https://doi.org/10.4081/ejh.2023.3766

2305

PDF: 1432

HTML: 22
Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells via regulation of miR-1234/TP53I11 axis

Jinbi Xie, Yong Ning, Lihang Zhang, Yuan Lin, Runsheng Guo, Shanjuan Wang

03-10-2022

https://doi.org/10.4081/ejh.2022.3477

2149

PDF: 726

HTML: 46
SPRR2B knockdown inhibits the proliferation and inflammatory response in M5-treated human HaCaT keratinocytes

Zhenzhen Ding, Chengchi Wang, Mingfeng Lv

06-08-2026

https://doi.org/10.4081/ejh.2026.4606

132

PDF: 88

HTML: 1
Downregulation of GMPS inhibited the proliferation of hepatocellular cancer cells via the regulation of STAT3/c-Myc pathway

Zhibin Guo, Juan Yu, Jing Sun, Sheng Yang, Jiang Pu

15-06-2026

https://doi.org/10.4081/ejh.2026.4541

172

PDF: 191

Supplementary: 33

HTML: 7
Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye

30-09-2021

https://doi.org/10.4081/ejh.2021.3224

3870

PDF: 1966

HTML: 45
DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu

03-05-2017

https://doi.org/10.4081/ejh.2017.2775

2771

PDF: 1084

HTML: 189
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He

20-04-2026

https://doi.org/10.4081/ejh.2026.4533

656

PDF: 321

HTML: 22
Effects of the lncRNA ENST00000623984 on colon cancer and the biological characteristics of colon cancer cells

Zhi-bao Liu, Jing-hua Zhang, Jing-hua Gao, Jian Shi

12-07-2021

https://doi.org/10.4081/ejh.2021.3215

2292

PDF: 611

HTML: 34
Effect of CDX2 on proliferation, invasion, migration, and apoptosis of duodenal cancer cells

Jun Pan, Yi Zhao, Yu Zhang, Yuhe Zhou, Fengxuan Zhang, Yitian Chen, Xiaoyuan Chu

24-04-2025

https://doi.org/10.4081/ejh.2025.4203

886

PDF: 396

HTML: 59
Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li

22-07-2024

https://doi.org/10.4081/ejh.2024.4048

2525

PDF: 1421

HTML: 26
MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9

Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen

12-01-2022

https://doi.org/10.4081/ejh.2022.3275

2230

PDF: 871

Supplementary: 170

HTML: 38
Continuous cyclic mechanical tension increases ank expression in endplate chondrocytes through the TGF-Î²1 and p38 pathway

H. Xu, X. Zhang, H. Wang, Y. Zhang, Y. Shi, X. Zhang

e28

25-09-2013

https://doi.org/10.4081/ejh.2013.e28

2439

PDF: 698

HTML: 225
Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

Jiapei Lv, Wang Yanting, Shan Wei

08-11-2023

https://doi.org/10.4081/ejh.2023.3867

2201

PDF: 1093

HTML: 65
An emerging potential therapeutic target for osteoporosis: LncRNA H19/miR-29a-3p axis

Ziqi Li, Zhinan Hong, Yuesheng Zheng, Yongwei Dong, Wei He, Yingjia Yuan, Junbiao Guo

06-11-2020

https://doi.org/10.4081/ejh.2020.3155

1647

PDF: 792

HTML: 17
LncRNA RP11-708J19.2 promotes colorectal cancer progression by binding to SIRT7 via regulating H3K18ac

Jiali Ma, Xianglong Tian, Yiwen Qiu, Chen Zhao, Jinghui Wang, Rongrong Jia

23-07-2026

https://doi.org/10.4081/ejh.2026.4560

287

PDF: 83

Supplementary: 37

HTML: 0
Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi

22-05-2024

https://doi.org/10.4081/ejh.2024.4033

1342

PDF: 589

HTML: 23
Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang

29-04-2024

https://doi.org/10.4081/ejh.2024.4019

2051

PDF: 785

HTML: 30
MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells

J. Zhang, J. Luo, J. Ni, L. Tang, H.P. Zhang, L. Zhang, J.F. Xu, D. Zheng

18-02-2014

https://doi.org/10.4081/ejh.2014.2262

3580

PDF: 1083

HTML: 334
Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng

03-09-2021

https://doi.org/10.4081/ejh.2021.3264

2098

PDF: 783

Supplementary: 159

HTML: 33
SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

Yiyu Qin, Jian Li, Hongchao Han, Yongliang Zheng, Haiming Lei, Yang Zhou, Hongyan Wu, Guozhe Zhang, Xiang Chen, Zhengping Chen

28-12-2023

https://doi.org/10.4081/ejh.2023.3899

1226

PDF: 398

HTML: 12
Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu

15-06-2026

https://doi.org/10.4081/ejh.2026.4569

212

PDF: 179

HTML: 8
Characterization of the role of RILP in cell migration

Azzurra Margiotta, Cinzia Progida, Oddmund Bakke, Cecilia Bucci

31-05-2017

https://doi.org/10.4081/ejh.2017.2783

2664

PDF: 1042

Supplementary: 265

Movie 1: 370

Movie 2: 421

HTML: 112
Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1466

PDF: 755

HTML: 25
Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li

25-10-2022

https://doi.org/10.4081/ejh.2022.3529

1863

PDF: 902

HTML: 41
Downregulation of SRPK2 promotes cell cycle arrest though E2F1 in non-small cell lung cancer

Xin Li, Shaoyu Yang, Minna Zhang, Shuhuan Xie, Zefeng Xie

11-12-2019

https://doi.org/10.4081/ejh.2019.3067

2154

PDF: 1170

HTML: 25
Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway

Li Chu, Suhong Ma, Zhiwei Chen, Wenfu Cao

01-04-2021

https://doi.org/10.4081/ejh.2021.3198

1907

PDF: 1034

HTML: 28
NOP14 regulates the growth, migration, and invasion of colorectal cancer cells by modulating the NRIP1/GSK-3β/β-catenin signaling pathway

Xuanjin Zhu, Weilu Jia, Yong Yan, Yong Huang, Bailin Wang

02-07-2021

https://doi.org/10.4081/ejh.2021.3246

3097

PDF: 824

HTML: 43
Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan

13-05-2024

https://doi.org/10.4081/ejh.2024.3917

2160

PDF: 915

HTML: 55
Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway

Y. Zhang, J. Wang, X. Cheng, B. Yi, X. Zhang, Q. Li

13-04-2015

https://doi.org/10.4081/ejh.2015.2467

4576

PDF: 1747

HTML: 904
The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi

16-05-2017

https://doi.org/10.4081/ejh.2017.2732

2768

PDF: 1080

HTML: 157
LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway

Yong Jiang, Chun-hui Xu, Ying Zhao, Yun-han Ji, Xin-tao Wang, Ying Liu

16-01-2023

https://doi.org/10.4081/ejh.2023.3526

2039

PDF: 890

HTML: 68
Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

Jun Lin, Liping Jiang, Kun Guo, Ning Feng

22-12-2022

https://doi.org/10.4081/ejh.2023.3528

2144

PDF: 1320

Supplementary: 155

HTML: 45
MiR-130a-5p contributed to the progression of endothelial cell injury by regulating FAS

Wei Wang, Wenbo Tang, Erbo Shan, Lei Zhang, Shiyuan Chen, Chaowen Yu, Yong Gao

31-05-2022

https://doi.org/10.4081/ejh.2022.3342

1320

PDF: 865

HTML: 32
SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang

18-05-2026

https://doi.org/10.4081/ejh.2026.4544

264

PDF: 260

Supplementary: 42

HTML: 12
High glucose inhibits neural differentiation by excessive autophagy via peroxisome proliferator-activated receptor gamma

Yin Pan, Di Qiu, Shu Chen, Xiaoxue Han, Ruiman Li

11-05-2023

https://doi.org/10.4081/ejh.2023.3691

1388

PDF: 954

HTML: 27
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

26-01-2026

https://doi.org/10.4081/ejh.2026.4422

758

PDF: 440

Supplementary: 67

Original gels: 69

HTML: 26
MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo

21-06-2022

https://doi.org/10.4081/ejh.2022.3426

1548

PDF: 944

HTML: 34
The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li

25-11-2021

https://doi.org/10.4081/ejh.2021.3323

2014

PDF: 773

HTML: 39
Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li

17-05-2023

https://doi.org/10.4081/ejh.2023.3612

1656

PDF: 978

Supplementary: 111

HTML: 28
Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei

17-03-2014

https://doi.org/10.4081/ejh.2014.2263

3791

PDF: 1085

HTML: 604
Transient receptor potential canonical 3/5 attenuate endothelial damage-induced neointima formation without affecting endothelial cell proliferation

Wenjun Zeng, Bei Liu, Lixia Yang, Ruiwei Guo

19-11-2025

https://doi.org/10.4081/ejh.2025.4311

468

PDF: 236

HTML: 26
Fluorescence and electron microscopy to visualize the intracellular fate of nanoparticles for drug delivery

M. Costanzo, F. Carton, A. Marengo, G. Berlier, B. Stella, S. Arpicco, M. Malatesta

14-04-2016

https://doi.org/10.4081/ejh.2016.2640

3325

PDF: 1451

HTML: 603
Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells

Yinping Zeng, Jiajun Huang, Tingting Duan, Xiaofeng Wang

28-05-2026

https://doi.org/10.4081/ejh.2026.4540

394

PDF: 288

HTML: 14
The clinical significance of UBE2C gene in progression of renal cell carcinoma

Zhiping Chen, Lanfeng Wang

29-03-2021

https://doi.org/10.4081/ejh.2021.3196

1995

PDF: 947

HTML: 35
Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

Chixian Zhang, Kai Bai, Dexu Li

14-04-2025

https://doi.org/10.4081/ejh.2025.4186

1479

PDF: 543

HTML: 35
Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study

M. Di Rosa, M.A. Szychlinska, D. Tibullo, L. Malaguarnera, G. Musumeci

16-09-2014

https://doi.org/10.4081/ejh.2014.2423

3103

PDF: 1261

HTML: 1614
PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNFα-CX3CR1 pathway

Xilei Li, Zhi Ye, Qulian Guo, E Wang, Yundan Pan

12-03-2021

https://doi.org/10.4081/ejh.2021.3184

2307

PDF: 975

HTML: 23
Activation of Hedgehog pathway by circEEF2/miR-625-5p/TRPM2 axis promotes prostate cancer cell proliferation through mitochondrial stress

ChenHui Zhu, LiJuan Lin, ChangQing Huang, ZhiHui Wu

11-11-2024

https://doi.org/10.4081/ejh.2024.4063

1713

PDF: 642

HTML: 24
SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu

03-03-2026

https://doi.org/10.4081/ejh.2026.4530

588

PDF: 489

HTML: 13
Seasonal expressions of SPAG11A and androgen receptor in the epididymis of the wild ground squirrels (Citellus dauricus Brandt)

Wenyang Yu, Ziwen Zhang, Pei Liu, Xiaoying Yang, Haolin Zhang, Zhengrong Yuan, Yingying Han, Qiang Weng

21-04-2020

https://doi.org/10.4081/ejh.2020.3111

1379

PDF: 661

HTML: 26
Knockdown of RAGE inhibits growth and invasion of gastric cancer cells

X.C. Xu, X. Abuduhadeer, W.B. Zhang, T. Li, H. Gao, Y.H. Wang

e36

18-11-2013

https://doi.org/10.4081/ejh.2013.e36

4434

PDF: 904

HTML: 272
2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini

19-10-2021

https://doi.org/10.4081/ejh.2021.3276

3205

PDF: 1772

Video 1: 272

Video 2: 320

HTML: 31
Ion channels alterations in the forebrain of high-fat diet fed rats

Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni

23-11-2021

https://doi.org/10.4081/ejh.2021.3305

2306

PDF: 1193

HTML: 47
P32 | BLOCKING CANCER CELL MOVEMENT: THE ROLE OF PAXILLIN AND EZRIN IN CERVICAL TUMOR M. Hałas-Wiśniewska¹, W. Arendt¹, M. Gagat^1,2, M. Izdebska¹ | ¹Department of Histology and Embryology, Nicolaus Copernicus University in Toruń, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Poland; ²Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland

21-08-2025

https://doi.org/10.4081/ejh.2025.4352

200
ECRG4 expression in normal rat tissues: expression study and literature review

A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro

18-05-2015

https://doi.org/10.4081/ejh.2015.2458

3127

PDF: 1226

Supplementary: 417

HTML: 1022
Atorvastatin reduces calcification in valve interstitial cells via the NF-κB signalling pathway by promoting Atg5-mediated autophagy

Menghui Chen, Su Liu

12-04-2024

https://doi.org/10.4081/ejh.2024.3983

1555

PDF: 639

HTML: 35
Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai

14-10-2022

https://doi.org/10.4081/ejh.2022.3510

1426

PDF: 727

HTML: 42
RNA therapeutics - Function, design and delivery

Carlo Alberto Redi

br7

17-06-2011

https://doi.org/10.4081/ejh.2011.br7

948

PDF: 467

HTML: 179
Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno

15-03-2018

https://doi.org/10.4081/ejh.2018.2841

15717

PDF: 7397

HTML: 541
Assessing the interactions between nanoparticles and biological barriers in vitro: a new challenge for microscopy techniques in nanomedicine

Flavia Carton, Manuela Malatesta

24-11-2022

https://doi.org/10.4081/ejh.2022.3603

1227

PDF: 527

HTML: 26
Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

M. Hinken, S. Halwachs, C. Kneuer, W. Honscha

e3

27-01-2011

https://doi.org/10.4081/ejh.2011.e3

1973

PDF: 760

HTML: 5832
Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu

11-05-2026

https://doi.org/10.4081/ejh.2026.4557

467

PDF: 714

Supplementary: 50

HTML: 8

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