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  Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

  Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin

  23-10-2024

  https://doi.org/10.4081/ejh.2024.4098

  2398

  PDF: 500

  HTML: 33
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  High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

  Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos

  17-02-2022

  https://doi.org/10.4081/ejh.2022.3360

  2612

  PDF: 1016

  HTML: 44
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  PD-L1 expression with QR1 and E1L3N antibodies according to histological ovarian cancer subtype: A series of 232 cases

  Caroline Eymerit-Morin, Anna Ilenko, Thomas Gaillard, Justine Varinot, Eva Compérat, Sofiane Bendifallah, Emile Darai

  10-03-2021

  https://doi.org/10.4081/ejh.2021.3185

  1853

  PDF: 779

  HTML: 27
• 

  Galunisertib enhances chimeric antigen receptor-modified T cell function

  Zhixiong Wang, Qian Liu, Na Risu, Jiayu Fu, Yan Zou, Jiaxing Tang, Long Li, Hui Liu, Guomin Zhou, Xuekai Zhu

  19-06-2020

  https://doi.org/10.4081/ejh.2020.3122

  2085

  PDF: 1108

  Supplementary: 170

  HTML: 20
• 

  VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas

  Ana Silvia Corlan, Anca Maria Cîmpean, Eugen Melnic, Marius Raica, Simona Sarb

  05-03-2019

  https://doi.org/10.4081/ejh.2019.3010

  1687

  PDF: 812

  HTML: 23
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  Immunohistochemical expression and clinicopathological assessment of PD-1, PD-L1, NY-ESO-1, and MAGE-A4 expression in highly aggressive soft tissue sarcomas

  Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi

  22-04-2022

  https://doi.org/10.4081/ejh.2022.3393

  1360

  PDF: 727

  HTML: 26
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  The role of miR-143-3p/FNDC1 axis on the progression of non-small cell lung cancer

  Zhanshu Ma, Qi Gao, Wenjing Xin, Lei Wang, Yan Chen, Chang Su, Songyan Gao, Ruiling Sun

  03-05-2023

  https://doi.org/10.4081/ejh.2023.3577

  2047

  PDF: 612

  HTML: 36
• 

  CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure

  S. Huang, S. Guo, F. Guo, Q. Yang, X. Xiao, M. Murata, S. Ohnishi, S. Kawanishi, N. Ma

  e1

  14-01-2013

  https://doi.org/10.4081/ejh.2013.e1

  2074

  PDF: 860

  HTML: 892
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  Fibroblast activating protein-α expression in squamous cell carcinoma of the esophagus in primary and irradiated tumors: the use of archival FFPE material for molecular techniques

  Renata Tabola, Magdalena Zaremba-Czogalla, Dagmara Baczynska, Roberto Cirocchi, Kamila Stach, Krzysztof Grabowski, Katarzyna Augoff

  20-06-2017

  https://doi.org/10.4081/ejh.2017.2793

  1868

  PDF: 767

  HTML: 100
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  Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis

  F. Rappa, E. Unti, P. Baiamonte, F. Cappello, N. Scibetta

  e20

  28-06-2013

  https://doi.org/10.4081/ejh.2013.e20

  2911

  PDF: 731

  HTML: 352
• 

  Expression of E-cadherin, Ki-67, and p53 in urinary bladder cancer in relation to progression, survival, and recurrence

  Stanislav Ziaran, Stefan Harsanyi, Katarina Bevizova, Zuzana Varchulova Novakova, Branislav Trebaticky, Peter Bujdak, Stefan Galbavy, Lubos Danisovic

  26-03-2020

  https://doi.org/10.4081/ejh.2020.3098

  1587

  PDF: 848

  HTML: 26
• 

  Immunopositivity for Siglec-15 in gastric cancer and its association with clinical and pathological parameters

  Michael Williams Leal Quirino, Michelly Cristiny Pereira, Maria de Fátima Deodato de Souza, Ivan da Rocha Pitta, Antônio Felix da Silva Filho, Mario S. de Souza Albuquerque, Amanda Pinheiro de Barros Albuquerque, Mário Rino Martins, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo

  04-03-2021

  https://doi.org/10.4081/ejh.2021.3174

  7684

  PDF: 1280

  Supplementary: 230

  HTML: 18
• 

  HLA-G expression and role in advanced-stage classical Hodgkin lymphoma

  G. Caocci, M. Greco, D. Fanni, G. Senes, R. Littera, S. Lai, P. Risso, C. Carcassi, G. Faa, G. La Nasa

  11-04-2016

  https://doi.org/10.4081/ejh.2016.2606

  2705

  PDF: 836

  HTML: 235
• 

  Assessing the interactions between nanoparticles and biological barriers in vitro: a new challenge for microscopy techniques in nanomedicine

  Flavia Carton, Manuela Malatesta

  24-11-2022

  https://doi.org/10.4081/ejh.2022.3603

  1164

  PDF: 478

  HTML: 22
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  Expression level of quiescin sulfhydryl oxidase 1 (QSOX1) in neuroblastomas

  D.G.B. Araújo, L. Nakao, P. Gozzo, C.D.A. Souza, V. Balderrama, E.S. Gugelmin, A.P. Kuczynski, M. Olandoski, L. de Noronha

  06-03-2014

  https://doi.org/10.4081/ejh.2014.2228

  3066

  PDF: 1262

  HTML: 365
• 

  MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells

  J. Zhang, J. Luo, J. Ni, L. Tang, H.P. Zhang, L. Zhang, J.F. Xu, D. Zheng

  18-02-2014

  https://doi.org/10.4081/ejh.2014.2262

  3496

  PDF: 1042

  HTML: 330
• 

  Are podoplanin and ezrin involved in the invasion process of the ameloblastomas?

  Y.F. Costa, K.C. Tjioe, S. Nonogaki, F.A. Soares, J.R. Pereira Lauris, D. Tostes Oliveira

  24-02-2015

  https://doi.org/10.4081/ejh.2015.2451

  2024

  PDF: 712

  HTML: 717
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  Deleted in Liver Cancer 2 (DLC2) protein expression in hepatocellular carcinoma

  Dominika Wolosz, Agnieszka Walczak, Grzegorz Szparecki, Michal Dwojak, Magdalena Winiarska, Ewa Wolinska, Barbara Gornicka

  18-02-2019

  https://doi.org/10.4081/ejh.2019.2981

  1487

  PDF: 759

  HTML: 31
• 

  Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

  J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei

  17-03-2014

  https://doi.org/10.4081/ejh.2014.2263

  3655

  PDF: 1036

  HTML: 592
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  miR-126 targeting GOLPH3 inhibits the epithelial-mesenchymal transition of gastric cancer BGC-823 cells and reduces cell invasion

  Jiancai Ouyang, Fuhu Song, He Li, Rui Yang, Haicheng Huang

  28-10-2020

  https://doi.org/10.4081/ejh.2020.3168

  1499

  PDF: 641

  HTML: 27
• 

  microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

  Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu

  10-05-2022

  https://doi.org/10.4081/ejh.2022.3333

  1839

  PDF: 924

  HTML: 31
• 

  Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

  A.C. Croce, G. Bottiroli

  12-12-2014

  https://doi.org/10.4081/ejh.2014.2461

  14385

  PDF: 6038

  HTML: 7978
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  Effect of carboplatin injection on Bcl-2 protein expression and apoptosis induction in Raji cells

  Peng Lin, Boliang Zhou, Haiying Yao, Ya-ping Guo

  09-07-2020

  https://doi.org/10.4081/ejh.2020.3134

  2137

  PDF: 593

  HTML: 28
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  Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

  Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng

  03-09-2021

  https://doi.org/10.4081/ejh.2021.3264

  2025

  PDF: 738

  Supplementary: 149

  HTML: 31
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  Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma

  Zhiyang Wang, Jing Li, Ziwei Liu, Ling Yue

  20-03-2023

  https://doi.org/10.4081/ejh.2023.3622

  1317

  PDF: 763

  HTML: 38
• 

  Imaging techniques in nanomedical research

  Laura Calderan, Manuela Malatesta

  01-07-2020

  https://doi.org/10.4081/ejh.2020.3151

  2070

  PDF: 821

  HTML: 22
• 

  SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

  Yiyu Qin, Jian Li, Hongchao Han, Yongliang Zheng, Haiming Lei, Yang Zhou, Hongyan Wu, Guozhe Zhang, Xiang Chen, Zhengping Chen

  28-12-2023

  https://doi.org/10.4081/ejh.2023.3899

  1153

  PDF: 342

  HTML: 10
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  PARP-1 protein expression in glioblastoma multiforme

  A. Galia, A.E. Calogero, R. Condorelli, F. Fraggetta, A. La Corte, F. Ridolfo, P. Bosco, R. Castiglione, M. Salemi

  e9

  27-02-2012

  https://doi.org/10.4081/ejh.2012.e9

  3338

  PDF: 1318

  HTML: 1819
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  Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

  Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang

  01-09-2025

  https://doi.org/10.4081/ejh.2025.4217

  538

  PDF: 221

  HTML: 11
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  Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

  Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang

  11-05-2023

  https://doi.org/10.4081/ejh.2023.3653

  1285

  PDF: 668

  HTML: 41
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  Reliable hexokinase 3 protein detection in human cell lines and primary tissue

  Yasmeen H. Mady, Carmen G. Kalbermatter, Maarij Khan, Anna M. Schläfli, Rina Mehmeti, Inti Zlobec, Lucine Christe, Mario P. Tschan

  12-03-2025

  https://doi.org/10.4081/ejh.2025.4175

  1935

  PDF: 474

  Supplementary: 65

  Uncropped Western blots: 58

  HTML: 14
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  Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

  Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li

  25-10-2022

  https://doi.org/10.4081/ejh.2022.3529

  1795

  PDF: 838

  HTML: 38
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  miR-29a-3p enhances the radiosensitivity of oral squamous cell carcinoma cells by inhibiting ADAM12

  Cuihong Jiang, Feng Liu , Shuai Xiao, Lili He, Wenqiong Wu, Qi Zhao

  27-09-2021

  https://doi.org/10.4081/ejh.2021.3295

  1427

  PDF: 988

  HTML: 29
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  Marine bisindole alkaloid: A potential apoptotic inducer in human cancer cells

  Sara Salucci, Sabrina Burattini, Francesca Buontempo, Ester Orsini, Lucia Furiassi, Michele Mari, Simone Lucarini, Alberto M. Martelli, Elisabetta Falcieri

  10-04-2018

  https://doi.org/10.4081/ejh.2018.2881

  2897

  PDF: 990

  HTML: 61
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  Immunohistochemical evidence of Muc1 expression during rat embryonic development

  E. Lacunza, V. Ferretti, C. Barbeito, A. Segal-Eiras, M. V. Croce

  e49

  26-11-2010

  https://doi.org/10.4081/ejh.2010.e49

  2181

  PDF: 703

  HTML: 2326
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  Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

  A.M. Schläfli, S. Berezowska, O. Adams, R. Langer, M.P. Tschan

  05-05-2015

  https://doi.org/10.4081/ejh.2015.2481

  8644

  PDF: 3306

  HTML: 2165
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  Vitamin D and vitamin D receptor in patients with ophthalmic pterygium

  Cristina Maxia, Daniela Murtas, Michela Corrias, Ignazio Zucca, Luigi Minerba, Franca Piras, Cristiana Marinelli, Maria Teresa Perra

  30-10-2017

  https://doi.org/10.4081/ejh.2017.2837

  1981

  PDF: 1018

  HTML: 77
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  Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma

  Lulu Le, Ji Luo, Haifang Wu, Ling Chen, Xiaoli Tang, Fen Fu

  30-03-2021

  https://doi.org/10.4081/ejh.2021.3226

  2096

  PDF: 875

  Supplementary: 196

  HTML: 30
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  Ultrastructural analysis of different human mesenchymal stem cells after in vitro expansion: a technical review

  M. Miko, L. Danisovic, A. Majidi, I. Varga

  26-10-2015

  https://doi.org/10.4081/ejh.2015.2528

  2656

  PDF: 872

  HTML: 841
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  Assessment of proliferating cell nuclear antigen and its relationship with proinflammatory cytokines and parameters of disease activity in multiple myeloma patients

  G. Tsirakis, C. A. Pappa, M. Kaparou, V. Katsomitrou, A. Hatzivasili, T. Alegakis, A. Xekalou, E. N. Stathopoulos, M. Alexandrakis

  e21

  01-08-2011

  https://doi.org/10.4081/ejh.2011.e21

  1365

  PDF: 583

  HTML: 1105
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  RANK/RANKL/OPG signaling pathways in necrotic jaw bone from bisphosphonate-treated subjects

  C. Di Nisio, V.L. Zizzari, S. Zara, M. Falconi, G. Teti, G. Tetè, A. Nori, V. Zavaglia, A. Cataldi

  03-02-2015

  https://doi.org/10.4081/ejh.2015.2455

  2887

  PDF: 1171

  HTML: 606
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  MiR-122-5p inhibits the epithelial mesenchymal transition of liver cancer cells by inducing hiPSCs to differentiate into hepatocyte-like cells

  Qianzhe Xing, Yanjie Xu, Ying Luo, Chenglong Li, Peng Wang, Bin Kang, Chengjun Lu

  06-05-2025

  https://doi.org/10.4081/ejh.2025.4190

  766

  PDF: 408

  HTML: 34
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  Angiotensin II: immunohistochemical study in Sardinian pterygium

  P. Demurtas, M. Corrias, I. Zucca, C. Maxia, F. Piras, P. Sirigu, M.T. Perra

  28-07-2014

  https://doi.org/10.4081/ejh.2014.2426

  2202

  PDF: 778

  HTML: 363
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  Immunohistochemical markers of CYP3A4 and CYP3A7: a new tool towards personalized pharmacotherapy of hepatocellular carcinoma

  D. Fanni, M. Manchia, F. Lai, C. Gerosa, R. Ambu, G. Faa

  11-04-2016

  https://doi.org/10.4081/ejh.2016.2614

  2417

  PDF: 871

  HTML: 416

• ANTIBODY-TO-IMAGING PIPELINE TO MONITOR DRUG-TARGET ENGAGEMENT IN BREAST TUMORS M. Barroso | Department of Molecular and Cellular Physiology Albany Medical College, Albany NY 12208, USA

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4270

  305
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  Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

  Jun Lin, Liping Jiang, Kun Guo, Ning Feng

  22-12-2022

  https://doi.org/10.4081/ejh.2023.3528

  2056

  PDF: 1243

  Supplementary: 137

  HTML: 39
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  OTX1 and OTX2 as possible molecular markers of sinonasal carcinomas and olfactory neuroblastomas

  Cristina Pirrone, Anna M. Chiaravalli, Alessandro Marando, Andrea Conti, Alessia Rainero, Andrea Pistochini, Francesco Lo Curto, Francesco Pasquali, Paolo Castelnuovo, Carlo Capella, Giovanni Porta

  09-02-2017

  https://doi.org/10.4081/ejh.2017.2730

  2758

  PDF: 1148

  HTML: 357
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  Mammaglobin, GATA-binding protein 3 (GATA3), and epithelial growth factor receptor (EGFR) expression in different breast cancer subtypes and their clinical significance

  Xin Kong, Qi Wang, Jie Li, Ming Li, Fusheng Deng, Chuanying Li

  07-04-2022

  https://doi.org/10.4081/ejh.2022.3315

  1715

  PDF: 816

  Supplementary: 161

  HTML: 19
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  Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

  Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu

  17-11-2025

  https://doi.org/10.4081/ejh.2025.4426

  957

  PDF: 503

  HTML: 21
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  Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

  Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye

  30-09-2021

  https://doi.org/10.4081/ejh.2021.3224

  3688

  PDF: 1912

  HTML: 41
• 

  Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

  Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera

  20-04-2022

  https://doi.org/10.4081/ejh.2022.3409

  1844

  PDF: 945

  HTML: 31
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  2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

  Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini

  19-10-2021

  https://doi.org/10.4081/ejh.2021.3276

  3119

  PDF: 1710

  Video 1: 249

  Video 2: 294

  HTML: 27
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  Cadmium influences the 5-Fluorouracil cytotoxic effects on breast cancer cells

  Y. Asara, J. A. Marchal, P. Bandiera, V. Mazzarello, L. G. Delogu, M. A. Sotgiu, A. Montella, R. Madeddu

  e1

  20-01-2012

  https://doi.org/10.4081/ejh.2012.e1

  1882

  PDF: 929

  HTML: 4534
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  Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

  Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno

  15-03-2018

  https://doi.org/10.4081/ejh.2018.2841

  15181

  PDF: 7214

  HTML: 501
• 

  Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

  Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang

  07-12-2023

  https://doi.org/10.4081/ejh.2023.3816

  1217

  PDF: 711

  HTML: 37
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  Establishment and biological characteristics of a Jingning chicken embryonic fibroblast bank

  C. Bai, D. Wang, C. Li, D. Jin, C. Li, W. Guan, Y. Ma

  e4

  29-03-2011

  https://doi.org/10.4081/ejh.2011.e4

  1920

  PDF: 737

  HTML: 6762
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  Investigation of seasonal changes in lipid synthesis and metabolism-related genes in the oviduct of Chinese brown frog (Rana dybowskii)

  Yankun Wang, Yuning Liu, Yawei Wang, Ao Zhang, Wenqian Xie, Haolin Zhang, Qiang Weng, Meiyu Xu

  20-12-2023

  https://doi.org/10.4081/ejh.2023.3890

  1382

  PDF: 685

  HTML: 25