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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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1.9
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3.7
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  • Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

    Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin
    23-10-2024
    https://doi.org/10.4081/ejh.2024.4098
    2631
    PDF: 567
    HTML: 40
  • High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

    Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos
    17-02-2022
    https://doi.org/10.4081/ejh.2022.3360
    2728
    PDF: 1078
    HTML: 47
  • PD-L1 expression with QR1 and E1L3N antibodies according to histological ovarian cancer subtype: A series of 232 cases

    Caroline Eymerit-Morin, Anna Ilenko, Thomas Gaillard, Justine Varinot, Eva Compérat, Sofiane Bendifallah, Emile Darai
    10-03-2021
    https://doi.org/10.4081/ejh.2021.3185
    1909
    PDF: 828
    HTML: 30
  • Galunisertib enhances chimeric antigen receptor-modified T cell function

    Zhixiong Wang, Qian Liu, Na Risu, Jiayu Fu, Yan Zou, Jiaxing Tang, Long Li, Hui Liu, Guomin Zhou, Xuekai Zhu
    19-06-2020
    https://doi.org/10.4081/ejh.2020.3122
    2150
    PDF: 1157
    Supplementary: 198
    HTML: 22
  • VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas

    Ana Silvia Corlan, Anca Maria Cîmpean, Eugen Melnic, Marius Raica, Simona Sarb
    05-03-2019
    https://doi.org/10.4081/ejh.2019.3010
    1744
    PDF: 844
    HTML: 28
  • Histopathological evaluation of RPL5 expression in triple-negative breast cancer: an integrated immunohistochemical and transcriptomic study

    Bing Zhao, Peiyuan Yu, Li Li , Zhenhui Zhao, Xiner Zhang
    23-07-2026
    https://doi.org/10.4081/ejh.2026.4599
    232
    PDF: 3
    HTML: 0
  • Immunohistochemical expression and clinicopathological assessment of PD-1, PD-L1, NY-ESO-1, and MAGE-A4 expression in highly aggressive soft tissue sarcomas

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi
    22-04-2022
    https://doi.org/10.4081/ejh.2022.3393
    1452
    PDF: 794
    HTML: 29
  • The role of miR-143-3p/FNDC1 axis on the progression of non-small cell lung cancer

    Zhanshu Ma, Qi Gao, Wenjing Xin, Lei Wang, Yan Chen, Chang Su, Songyan Gao, Ruiling Sun
    03-05-2023
    https://doi.org/10.4081/ejh.2023.3577
    2166
    PDF: 649
    HTML: 40
  • CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure

    S. Huang, S. Guo, F. Guo, Q. Yang, X. Xiao, M. Murata, S. Ohnishi, S. Kawanishi, N. Ma
    e1
    14-01-2013
    https://doi.org/10.4081/ejh.2013.e1
    2157
    PDF: 923
    HTML: 895
  • Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis

    F. Rappa, E. Unti, P. Baiamonte, F. Cappello, N. Scibetta
    e20
    28-06-2013
    https://doi.org/10.4081/ejh.2013.e20
    2944
    PDF: 784
    HTML: 359
  • Fibroblast activating protein-α expression in squamous cell carcinoma of the esophagus in primary and irradiated tumors: the use of archival FFPE material for molecular techniques

    Renata Tabola, Magdalena Zaremba-Czogalla, Dagmara Baczynska, Roberto Cirocchi, Kamila Stach, Krzysztof Grabowski, Katarzyna Augoff
    20-06-2017
    https://doi.org/10.4081/ejh.2017.2793
    1910
    PDF: 804
    HTML: 102
  • Expression of E-cadherin, Ki-67, and p53 in urinary bladder cancer in relation to progression, survival, and recurrence

    Stanislav Ziaran, Stefan Harsanyi, Katarina Bevizova, Zuzana Varchulova Novakova, Branislav Trebaticky, Peter Bujdak, Stefan Galbavy, Lubos Danisovic
    26-03-2020
    https://doi.org/10.4081/ejh.2020.3098
    1654
    PDF: 883
    HTML: 32
  • Immunopositivity for Siglec-15 in gastric cancer and its association with clinical and pathological parameters

    Michael Williams Leal Quirino, Michelly Cristiny Pereira, Maria de Fátima Deodato de Souza, Ivan da Rocha Pitta, Antônio Felix da Silva Filho, Mario S. de Souza Albuquerque, Amanda Pinheiro de Barros Albuquerque, Mário Rino Martins, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo
    04-03-2021
    https://doi.org/10.4081/ejh.2021.3174
    8785
    PDF: 1317
    Supplementary: 244
    HTML: 21
  • HLA-G expression and role in advanced-stage classical Hodgkin lymphoma

    G. Caocci, M. Greco, D. Fanni, G. Senes, R. Littera, S. Lai, P. Risso, C. Carcassi, G. Faa, G. La Nasa
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2606
    2761
    PDF: 889
    HTML: 239
  • Assessing the interactions between nanoparticles and biological barriers in vitro: a new challenge for microscopy techniques in nanomedicine

    Flavia Carton, Manuela Malatesta
    24-11-2022
    https://doi.org/10.4081/ejh.2022.3603
    1227
    PDF: 529
    HTML: 26
  • Expression level of quiescin sulfhydryl oxidase 1 (QSOX1) in neuroblastomas

    D.G.B. Araújo, L. Nakao, P. Gozzo, C.D.A. Souza, V. Balderrama, E.S. Gugelmin, A.P. Kuczynski, M. Olandoski, L. de Noronha
    06-03-2014
    https://doi.org/10.4081/ejh.2014.2228
    3129
    PDF: 1311
    HTML: 366
  • MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells

    J. Zhang, J. Luo, J. Ni, L. Tang, H.P. Zhang, L. Zhang, J.F. Xu, D. Zheng
    18-02-2014
    https://doi.org/10.4081/ejh.2014.2262
    3585
    PDF: 1083
    HTML: 334
  • Are podoplanin and ezrin involved in the invasion process of the ameloblastomas?

    Y.F. Costa, K.C. Tjioe, S. Nonogaki, F.A. Soares, J.R. Pereira Lauris, D. Tostes Oliveira
    24-02-2015
    https://doi.org/10.4081/ejh.2015.2451
    2060
    PDF: 733
    HTML: 720
  • Deleted in Liver Cancer 2 (DLC2) protein expression in hepatocellular carcinoma

    Dominika Wolosz, Agnieszka Walczak, Grzegorz Szparecki, Michal Dwojak, Magdalena Winiarska, Ewa Wolinska, Barbara Gornicka
    18-02-2019
    https://doi.org/10.4081/ejh.2019.2981
    1537
    PDF: 803
    HTML: 36
  • Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

    J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei
    17-03-2014
    https://doi.org/10.4081/ejh.2014.2263
    3798
    PDF: 1088
    HTML: 604
  • miR-126 targeting GOLPH3 inhibits the epithelial-mesenchymal transition of gastric cancer BGC-823 cells and reduces cell invasion

    Jiancai Ouyang, Fuhu Song, He Li, Rui Yang, Haicheng Huang
    28-10-2020
    https://doi.org/10.4081/ejh.2020.3168
    1548
    PDF: 675
    HTML: 30
  • microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

    Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu
    10-05-2022
    https://doi.org/10.4081/ejh.2022.3333
    2260
    PDF: 974
    HTML: 34
  • Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

    A.C. Croce, G. Bottiroli
    12-12-2014
    https://doi.org/10.4081/ejh.2014.2461
    15128
    PDF: 6255
    HTML: 8012
  • Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

    Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng
    03-09-2021
    https://doi.org/10.4081/ejh.2021.3264
    2099
    PDF: 785
    Supplementary: 159
    HTML: 33
  • Effect of carboplatin injection on Bcl-2 protein expression and apoptosis induction in Raji cells

    Peng Lin, Boliang Zhou, Haiying Yao, Ya-ping Guo
    09-07-2020
    https://doi.org/10.4081/ejh.2020.3134
    2198
    PDF: 627
    HTML: 31
  • Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma

    Zhiyang Wang, Jing Li, Ziwei Liu, Ling Yue
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3622
    1839
    PDF: 892
    HTML: 41
  • Imaging techniques in nanomedical research

    Laura Calderan, Manuela Malatesta
    01-07-2020
    https://doi.org/10.4081/ejh.2020.3151
    2129
    PDF: 860
    HTML: 26
  • SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

    Yiyu Qin, Jian Li, Hongchao Han, Yongliang Zheng, Haiming Lei, Yang Zhou, Hongyan Wu, Guozhe Zhang, Xiang Chen, Zhengping Chen
    28-12-2023
    https://doi.org/10.4081/ejh.2023.3899
    1227
    PDF: 400
    HTML: 12
  • PARP-1 protein expression in glioblastoma multiforme

    A. Galia, A.E. Calogero, R. Condorelli, F. Fraggetta, A. La Corte, F. Ridolfo, P. Bosco, R. Castiglione, M. Salemi
    e9
    27-02-2012
    https://doi.org/10.4081/ejh.2012.e9
    3497
    PDF: 1387
    HTML: 1882
  • Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

    Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3653
    1484
    PDF: 734
    HTML: 44
  • Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

    Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang
    01-09-2025
    https://doi.org/10.4081/ejh.2025.4217
    612
    PDF: 272
    HTML: 14
  • Reliable hexokinase 3 protein detection in human cell lines and primary tissue

    Yasmeen H. Mady, Carmen G. Kalbermatter, Maarij Khan, Anna M. Schläfli, Rina Mehmeti, Inti Zlobec, Lucine Christe, Mario P. Tschan
    12-03-2025
    https://doi.org/10.4081/ejh.2025.4175
    2031
    PDF: 516
    Supplementary: 75
    Uncropped Western blots: 74
    HTML: 24
  • Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

    Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li
    25-10-2022
    https://doi.org/10.4081/ejh.2022.3529
    1865
    PDF: 903
    HTML: 41
  • Marine bisindole alkaloid: A potential apoptotic inducer in human cancer cells

    Sara Salucci, Sabrina Burattini, Francesca Buontempo, Ester Orsini, Lucia Furiassi, Michele Mari, Simone Lucarini, Alberto M. Martelli, Elisabetta Falcieri
    10-04-2018
    https://doi.org/10.4081/ejh.2018.2881
    2946
    PDF: 1042
    HTML: 66
  • miR-29a-3p enhances the radiosensitivity of oral squamous cell carcinoma cells by inhibiting ADAM12

    Cuihong Jiang, Feng Liu , Shuai Xiao, Lili He, Wenqiong Wu, Qi Zhao
    27-09-2021
    https://doi.org/10.4081/ejh.2021.3295
    1495
    PDF: 1112
    HTML: 32
  • Immunohistochemical evidence of Muc1 expression during rat embryonic development

    E. Lacunza, V. Ferretti, C. Barbeito, A. Segal-Eiras, M. V. Croce
    e49
    26-11-2010
    https://doi.org/10.4081/ejh.2010.e49
    2261
    PDF: 731
    HTML: 2420
  • Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

    A.M. Schläfli, S. Berezowska, O. Adams, R. Langer, M.P. Tschan
    05-05-2015
    https://doi.org/10.4081/ejh.2015.2481
    9200
    PDF: 3407
    HTML: 2178
  • Vitamin D and vitamin D receptor in patients with ophthalmic pterygium

    Cristina Maxia, Daniela Murtas, Michela Corrias, Ignazio Zucca, Luigi Minerba, Franca Piras, Cristiana Marinelli, Maria Teresa Perra
    30-10-2017
    https://doi.org/10.4081/ejh.2017.2837
    2037
    PDF: 1059
    HTML: 78
  • Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma

    Lulu Le, Ji Luo, Haifang Wu, Ling Chen, Xiaoli Tang, Fen Fu
    30-03-2021
    https://doi.org/10.4081/ejh.2021.3226
    2190
    PDF: 937
    Supplementary: 208
    HTML: 34
  • Ultrastructural analysis of different human mesenchymal stem cells after in vitro expansion: a technical review

    M. Miko, L. Danisovic, A. Majidi, I. Varga
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2528
    2713
    PDF: 906
    HTML: 843
  • Assessment of proliferating cell nuclear antigen and its relationship with proinflammatory cytokines and parameters of disease activity in multiple myeloma patients

    G. Tsirakis, C. A. Pappa, M. Kaparou, V. Katsomitrou, A. Hatzivasili, T. Alegakis, A. Xekalou, E. N. Stathopoulos, M. Alexandrakis
    e21
    01-08-2011
    https://doi.org/10.4081/ejh.2011.e21
    1415
    PDF: 612
    HTML: 1221
  • Angiotensin II: immunohistochemical study in Sardinian pterygium

    P. Demurtas, M. Corrias, I. Zucca, C. Maxia, F. Piras, P. Sirigu, M.T. Perra
    28-07-2014
    https://doi.org/10.4081/ejh.2014.2426
    2231
    PDF: 819
    HTML: 367
  • RANK/RANKL/OPG signaling pathways in necrotic jaw bone from bisphosphonate-treated subjects

    C. Di Nisio, V.L. Zizzari, S. Zara, M. Falconi, G. Teti, G. Tetè, A. Nori, V. Zavaglia, A. Cataldi
    03-02-2015
    https://doi.org/10.4081/ejh.2015.2455
    2994
    PDF: 1212
    HTML: 609
  • MiR-122-5p inhibits the epithelial mesenchymal transition of liver cancer cells by inducing hiPSCs to differentiate into hepatocyte-like cells

    Qianzhe Xing, Yanjie Xu, Ying Luo, Chenglong Li, Peng Wang, Bin Kang, Chengjun Lu
    06-05-2025
    https://doi.org/10.4081/ejh.2025.4190
    849
    PDF: 457
    HTML: 37
  • Immunohistochemical markers of CYP3A4 and CYP3A7: a new tool towards personalized pharmacotherapy of hepatocellular carcinoma

    D. Fanni, M. Manchia, F. Lai, C. Gerosa, R. Ambu, G. Faa
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2614
    2476
    PDF: 918
    HTML: 420
  • ANTIBODY-TO-IMAGING PIPELINE TO MONITOR DRUG-TARGET ENGAGEMENT IN BREAST TUMORS M. Barroso | Department of Molecular and Cellular Physiology Albany Medical College, Albany NY 12208, USA

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4270
    349
  • Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

    Jun Lin, Liping Jiang, Kun Guo, Ning Feng
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3528
    2150
    PDF: 1322
    Supplementary: 155
    HTML: 45
  • OTX1 and OTX2 as possible molecular markers of sinonasal carcinomas and olfactory neuroblastomas

    Cristina Pirrone, Anna M. Chiaravalli, Alessandro Marando, Andrea Conti, Alessia Rainero, Andrea Pistochini, Francesco Lo Curto, Francesco Pasquali, Paolo Castelnuovo, Carlo Capella, Giovanni Porta
    09-02-2017
    https://doi.org/10.4081/ejh.2017.2730
    2864
    PDF: 1183
    HTML: 362
  • Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

    Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu
    17-11-2025
    https://doi.org/10.4081/ejh.2025.4426
    1131
    PDF: 549
    HTML: 22
  • Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

    Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye
    30-09-2021
    https://doi.org/10.4081/ejh.2021.3224
    3873
    PDF: 1970
    HTML: 45
  • Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

    Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera
    20-04-2022
    https://doi.org/10.4081/ejh.2022.3409
    1893
    PDF: 1011
    HTML: 34
  • Mammaglobin, GATA-binding protein 3 (GATA3), and epithelial growth factor receptor (EGFR) expression in different breast cancer subtypes and their clinical significance

    Xin Kong, Qi Wang, Jie Li, Ming Li, Fusheng Deng, Chuanying Li
    07-04-2022
    https://doi.org/10.4081/ejh.2022.3315
    1820
    PDF: 868
    Supplementary: 172
    HTML: 19
  • Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

    Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno
    15-03-2018
    https://doi.org/10.4081/ejh.2018.2841
    15744
    PDF: 7407
    HTML: 541
  • Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

    Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang
    07-12-2023
    https://doi.org/10.4081/ejh.2023.3816
    1266
    PDF: 760
    HTML: 40
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    3207
    PDF: 1774
    Video 1: 273
    Video 2: 321
    HTML: 31
  • Cadmium influences the 5-Fluorouracil cytotoxic effects on breast cancer cells

    Y. Asara, J. A. Marchal, P. Bandiera, V. Mazzarello, L. G. Delogu, M. A. Sotgiu, A. Montella, R. Madeddu
    e1
    20-01-2012
    https://doi.org/10.4081/ejh.2012.e1
    1923
    PDF: 959
    HTML: 4626
  • Establishment and biological characteristics of a Jingning chicken embryonic fibroblast bank

    C. Bai, D. Wang, C. Li, D. Jin, C. Li, W. Guan, Y. Ma
    e4
    29-03-2011
    https://doi.org/10.4081/ejh.2011.e4
    1968
    PDF: 777
    HTML: 6767
  • Investigation of seasonal changes in lipid synthesis and metabolism-related genes in the oviduct of Chinese brown frog (Rana dybowskii)

    Yankun Wang, Yuning Liu, Yawei Wang, Ao Zhang, Wenqian Xie, Haolin Zhang, Qiang Weng, Meiyu Xu
    20-12-2023
    https://doi.org/10.4081/ejh.2023.3890
    1517
    PDF: 791
    HTML: 34
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
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20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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