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P59 | IMMUNOHISTOCHEMISTRY ANALYSIS TO DETECT A MOLECULAR SIGNATURE IN INTERVERTEBRAL DISC DEGENERATION L. Penolazzi1, R. Nadalini1, C. Sief1, E. Lambertini2, C. Angelini3, R. Piva1 | 1Department of Neurosciences and rehabilitation, University of Ferrara, Italy; 2Laboratorio Centralizzato di ricerca preclinica, University of Ferrara, Italy; 3Department of Translational Medicine, University of Ferrara, Italy
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P22 | EXPLORING THE UNEXPECTED DUAL ROLE OF GARLIC DERIVATIVES IN REGULATING INVASIVENESS IN BREAST CANCER SUBTYPES M. Dell’Aira1, S. Grassilli2, M. Pierantoni1, V. Bertagnolo1, F. Brugnoli1 | 1Department of Translational Medicine, University of Ferrara, Ferrara, Italy; 2Department of Environmental Sciences and Prevention and LTTA Centre, University of Ferrara, Ferrara, Italy
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REDUCING PACLITAXEL-INDUCED PERIPHERAL NEUROTOXICITY VIA LIPOSOMAL DRUG TARGETING Molteni L1, Persico A2, Kravicz M3, Antoniou A4, Peqini K4, Mantecca P2, Nicolini G1, Pellegrino S4, Re F3 and Bragato C2 | 1Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; 2POLARIS Research Center, Dept. of Earth and Environmental Sciences, University of Milano-Bicocca, Milan, Italy; 3School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; 4Department of Pharmaceutical Sciences, University of Milan, Milan, Italy
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P31 | MORPHOLOGICAL AND ULTRASTRUCTURAL MARKERS OF RADIATION-INDUCED ADIPOSE TISSUE DAMAGE E. Guerra1, S. Lattanzio1, G. Furini2, G. Scabia2, E. Mota-Silva2, M. Maffei2, S. Cinti3, R. Di Pietro1 | 1Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2CNR Institute of Clinical Physiology, Pisa, Italy; 3Department of Experimental and Clinical Medicine, Center of Obesity, Università Politecnica delle Marche (Polytechnic University of Marche), Ancona, Italy
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P32 | BLOCKING CANCER CELL MOVEMENT: THE ROLE OF PAXILLIN AND EZRIN IN CERVICAL TUMOR M. Hałas-Wiśniewska1, W. Arendt1, M. Gagat1,2, M. Izdebska1 | 1Department of Histology and Embryology, Nicolaus Copernicus University in Toruń, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Poland; 2Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland
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THE LINK BETWEEN NEURONAL BRANCHING AND PAIN Dotta S1, Muraglia L1, Musso G1, Rother F2,3, Pritz. C1, Luzzati F1, Bader M2,3,4, Buffo A1, Vercelli A1 and Marvaldi L1 | 1Department of Neuroscience Rita Levi Montalcini, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Orbassano (TO), Italy; 2Max Delbrück Center for Molecular Medicine, Berlin, Germany; 3Center for Structural and Cellular Biology in Medicine, Institute of Biology, University of Lübeck, Germany; 4Charité, Universitätsmedizin, Berlin, Germany
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USE OF HIGH-DEFINITION IMAGING FLOW CYTOMETRY AND A.I. TO ENUMERATE AND CHARACTERISE CIRCULATING TUMOUR CELLS S. Saravi1, S. Panfilov2, E. Karteris2 | 1College of Health, Medicine and Life Sciences, Brunel University of London, UK; 2College of Health, Medicine and Life Sciences, Brunel University of London, UK
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MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices
2371PDF: 1157MIAQuant user Manual: 252MIAQuant source code: 313HTML: 72 -
Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment
1784PDF: 937Supplementary: 117HTML: 29 -
P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY S. Blando1, E. Boschetti1, I. Neri1, L. Caporali2, C. Fiorini2, D. Ormanbekova2, C. Malagelada3, I. Rusciano1, V. Carelli2, R. De Giorgio4, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Italy; 2IRCCS Institute of Neurological Sciences of Bologna, Neurogenetics Program, Bologna, Italy; 3Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; 4Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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P78 | THE ROLE OF EXTRACELLULAR VESICLES DERIVED FROM MESENCHYMAL STROMAL CELLS IN MYOFIBER REGENERATION A. Longhin1, V. Gatta2, G. Teti2, C. Sassoli3, F. Chellini3, A. Tani3, M. Parigi3, R. Garella3, F. Palmieri3, R. Squecco3, M. Mattioli Belmonte4, C. Licini4, A. La Contana4, S. Zecchi Orlandini3, M. Falconi1 | 1Dep. Medical and Surgical Sciences, University of Bologna, Bologna, Italy; 2Dep. Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy; 3Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 4Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy
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P11 | DOMINO TRANSPLANTATION IN MNGIE: IS THE LIVER A SUITABLE GRAFT? E. Boschetti1, I. Neri1, S. Blando1, C. Malagelada2, L. Caporali3, R. D’Angelo4, R. Rinaldi4, S. Mongiorgi1, V. Carelli3, R. De Giorgio5, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum – University of Bologna, Italy; 2Digestive System Research Unit, University Hospital Vall d’Hebron; Barcelona, Spain; 3IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; 4IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 5Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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PERICYTE INVOLVEMENT IN THE PATHOGENESIS OF COLVI-RELATED MYOPATHIES: INSIGHTS INTO NG2–COLVI AXIS A. Fazio1, C. Evangelisti1, P. Sabatelli2, A. Cappellini1, A. Di Martino3, C. Faldini3, L. Manzoli1, S. Ratti1 | 1Cellular Signalling Laboratory, University of Bologna, DIBINEM, Bologna, Italy; 2CNR Institute of Molecular Genetics «Luigi Luca Cavalli-Sforza”, Unit of Bologna, Bologna, Italy; 3IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
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MORPHOLOGICAL AND SYNAPTIC CHANGES OF THE CORTICAL GABAERGIC INHIBITORY SYSTEM IN SPINAL MUSCULAR ATROPHY Menduti G1,2, Ferrini F3,4, Caretto A1,2, Hassan A5,6, di Vito R6,7, Beltrando G1,2, Marnetto D2, Usiello A6,7, Di Cunto F1,2, Boido M1,2, and Vercelli A1,2 | 1Neuroscience Institute Cavalieri Ottolenghi, Orbassano, Turin, Italy; 2Department of Neuroscience «Rita Levi Montalcini», University of Turin, Italy; 3Department of Veterinary Sciences, University of Turin, Grugliasco, Turin, Italy; 4Department of Psychiatry and Neuroscience, Université Laval, Québec, Canada; 5European School of Molecular medicine, University of Milan, Italy; 6Laboratory of Translational Neuroscience, Ceinge Biotecnologie Avanzate, Naples, Italy; 7Department of Environmental, Biological and Pharmaceutical Science and Technologies, Università degli Studi della Campania Luigi Vanvitelli, Caserta, Italy
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UNRAVELING GLIAL REMODELING IN SPACE AND TIME DURING GLIOBLASTOMA EVOLUTION Riccio L1, De Luca C1, Rega C1, Papa M1 and Virtuoso A1 | 1Laboratory of Neuronal Networks Morphology and System Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy
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CONNEXIN 43 HEMICHANNELS CAN DRIVE THE GLIOBLASTOMA SPREADING Virtuoso A1, De Luca C1, Altieri R2, Milior G3, Moulard J3, Huberfeld J3, Cirillo G1, Barbarisi M2, Rouach N3 and Papa M1 | 1Laboratory of Neural Network Morphology and Systems Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; 2Multidisciplinary Department of Medical, Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy; 3Interdisciplinary Research Center in Biology, College de France, CNRS, INSERM, Labex Memolife, Université PSL, Paris, France
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Histological and Histochemical Methods - Theory and practice
4021PDF: 2091HTML: 180 -
Varying effects of EGF, HGF and TGFβ on formation of invadopodia and invasiveness of melanoma cell lines of different origin
2213PDF: 903Supplementary: 276HTML: 415 -
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MICROBIAL INFLUENCE ON PERIPHERAL NERVOUS SYSTEM: INSIGHTS FROM GERM-FREE AND RECOLONIZED MICE Farzin S1, Pellegrino D1, Cicconetti C2, Bertone F1, Oliviero S2, Basic M3, Bolsega S3, Haastert-Talini K4, Cescon M5, Gambarotta G1 and Ronchi G1 | 1Department of Clinical and Biological Sciences (DSCB), University of Torino, Orbassano, (Torino), Italy; 2Department of Life Sciences and System Biology, University of Torino, Torino, Italy; 3Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, Hannover, Lower- Saxony, Germany; 4Institute of Neuroanatomy and Cell Biology, Hannover Medical School, Hannover, Lower-Saxony, Germany; 5Department of Molecular Medicine, University of Padova, Padova, Italy
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P85 | ALTERATION OF SUBMUCOSAL AND MYENTERIC GANGLIA IN SEVERE GUT DYSMOTILITY: A QUANTITATIVE MORPHOMETRIC ANALYSIS H. Yaghi1, E. Boschetti1, S. Blando1, I. Neri1, C. Malagelada2, R. De Giorgio3, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Bologna, Italy; 2Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; 3Department of Translational Medicine, Università di Ferrara, Ferrara, Italy
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Mouse oocyte development - Methods and Protocols
1295PDF: 629HTML: 15 -
Cellular programming and reprogramming - Methods and protocols
859PDF: 467HTML: 192 -
P35 | EARLY LIFE STRESS CAN CAUSE CHANGES IN THE HIPPO SIGNALING PATHWAY IN RAT OVARIES İ. İnanç1, E. Baysal1, O. Bender2, A. Atalay2, E. Erdemli1 | 1Ankara University, Faculty of Medicine, Department of Histology and Embryology, Ankara, Türkiye; 2Ankara University, Biotechnology Institute, Ankara, Türkiye
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