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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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1.9
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  • Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi
    23-06-2022
    https://doi.org/10.4081/ejh.2022.3377
    1955
    PDF: 1104
    HTML: 67
  • Swertiamarin suppresses proliferation, migration, and invasion of hepatocellular carcinoma cells via negative regulation of FRAT1

    Shufeng Xiao, Haoren Tang, Yao Bai, Renchao Zou, Zongfang Ren, Xuesong Wu, Zhitian Shi, Song Lan, Wei Liu, Tiangen Wu, Cheng Zhang, Lin Wang
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3169
    1763
    PDF: 856
    HTML: 64
  • Alarin regulates RyR2 and SERCA2 to improve cardiac function in heart failure with preserved ejection fraction

    Jinshuang Li, Dawei Xu, Ce Shi, Chunqi Cheng, Ziheng Xu, Xingjuan Gao, Yong Cheng
    28-10-2024
    https://doi.org/10.4081/ejh.2024.4122
    1744
    PDF: 735
    HTML: 58
  • LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma

    Nuobei Zhang, Hao Shen, Shenan Huang, Fenfen Wang, Huifang Liu, Fen Xie, Lei Jiang, Xin Chen
    16-11-2021
    https://doi.org/10.4081/ejh.2021.3300
    1451
    PDF: 834
    HTML: 91
  • Expression pattern of thymosin beta 4 in the adult human liver

    S. Nemolato, P. Van Eyken, T. Cabras, F. Cau, M.U. Fanari, A. Locci, D. Fanni, C.L.P. Gerosa, I. Messana, M. Castagnola, G. Faa
    e25
    07-09-2011
    https://doi.org/10.4081/ejh.2011.e25
    1760
    PDF: 809
    HTML: 1425
  • 12 | IMPACT OF COCAINE ON GASTROINTESTINAL BARRIER INTEGRITY S. Boccia1, B. Sgangarella Valvano2, A. Mileo3, A. Nebbioso4, A. De Luca1, A. Capaldo5, M. De Falco5|6 | 1Dept. of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; 2Dept. of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy; 3Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; 4Dept. of Precision Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; 5Dept. of Biology, University of Naples Federico II, Naples, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4630
    263
    PDF: 104
  • SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

    Yiyu Qin, Jian Li, Hongchao Han, Yongliang Zheng, Haiming Lei, Yang Zhou, Hongyan Wu, Guozhe Zhang, Xiang Chen, Zhengping Chen
    28-12-2023
    https://doi.org/10.4081/ejh.2023.3899
    1374
    PDF: 458
    HTML: 41
  • Detection and characterisation of NAD(P)H-diaphorase activity in Dictyostelium discoideum cells (Protozoa)

    A. Amaroli, M.G. Chessa
    e47
    29-10-2012
    https://doi.org/10.4081/ejh.2012.e47
    1670
    PDF: 756
    HTML: 559
  • P79 | AN INNOVATIVE FUNCTIONAL COOKIE MODULATES THE MUCOSA AND MYENTERIC PLEXUS IN THE GUT OF 3xTg-AD MOUSE MODEL OF ALZHEIMER’S DISEASE V. Bellitto1, F. Grasselli1, L. Lucernoni1, I. Martinelli2, E. Vittadini1, A.M. Eleuteri1, L. Bonfili1, S.K. Tayebati2, D. Tomassoni1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal Sciences and Health Products, University of Camerino, Camerino, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4405
    393
  • Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

    Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou
    22-06-2022
    https://doi.org/10.4081/ejh.2022.3394
    2270
    PDF: 1456
    HTML: 64
  • Twenty years of histochemistry in the third millennium, browsing the scientific literature

    Carlo Pellicciari
    29-12-2020
    https://doi.org/10.4081/ejh.2020.3213
    1539
    PDF: 613
    HTML: 44
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    2067
    PDF: 349
    HTML: 64
  • Neurokinin-1 receptor is highly expressed in cervical cancer and its antagonist induces cervical cancer cell apoptosis

    Liyun Guan, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang
    11-01-2023
    https://doi.org/10.4081/ejh.2023.3570
    1681
    PDF: 798
    HTML: 59
  • Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma

    Lulu Le, Ji Luo, Haifang Wu, Ling Chen, Xiaoli Tang, Fen Fu
    30-03-2021
    https://doi.org/10.4081/ejh.2021.3226
    2329
    PDF: 996
    Supplementary: 244
    HTML: 55
  • Histochemical properties of sialic acids and antimicrobial substances in canine anal glands

    T. Nara, T. Yasui, O. Fujimori, W. Meyer, A. Tsukise
    e29
    15-09-2011
    https://doi.org/10.4081/ejh.2011.e29
    2065
    PDF: 792
    HTML: 3475
  • Downregulation of SRPK2 promotes cell cycle arrest though E2F1 in non-small cell lung cancer

    Xin Li, Shaoyu Yang, Minna Zhang, Shuhuan Xie, Zefeng Xie
    11-12-2019
    https://doi.org/10.4081/ejh.2019.3067
    2344
    PDF: 1239
    HTML: 53
  • Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

    Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng
    03-09-2021
    https://doi.org/10.4081/ejh.2021.3264
    2269
    PDF: 850
    Supplementary: 212
    HTML: 65
  • MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices

    Elena Casiraghi, Mara Cossa, Veronica Huber, Licia Rivoltini, Matteo Tozzi, Antonello Villa, Barbara Vergani
    02-11-2017
    https://doi.org/10.4081/ejh.2017.2838
    2727
    PDF: 1301
    MIAQuant user Manual: 347
    MIAQuant source code: 429
    HTML: 114
  • P85 | ALTERATION OF SUBMUCOSAL AND MYENTERIC GANGLIA IN SEVERE GUT DYSMOTILITY: A QUANTITATIVE MORPHOMETRIC ANALYSIS H. Yaghi1, E. Boschetti1, S. Blando1, I. Neri1, C. Malagelada2, R. De Giorgio3, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Bologna, Italy; 2Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; 3Department of Translational Medicine, Università di Ferrara, Ferrara, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4411
    381
  • Distribution of alpha-synuclein in normal human jejunum and its relations with the chemosensory and neuroendocrine system

    Arianna Casini, Romina Mancinelli, Caterina Loredana Mammola, Luigi Pannarale, Piero Chirletti, Paolo Onori, Rosa Vaccaro
    02-11-2021
    https://doi.org/10.4081/ejh.2021.3310
    3153
    PDF: 1329
    HTML: 120
  • Marine bisindole alkaloid: A potential apoptotic inducer in human cancer cells

    Sara Salucci, Sabrina Burattini, Francesca Buontempo, Ester Orsini, Lucia Furiassi, Michele Mari, Simone Lucarini, Alberto M. Martelli, Elisabetta Falcieri
    10-04-2018
    https://doi.org/10.4081/ejh.2018.2881
    3111
    PDF: 1099
    HTML: 91
  • Erratum - Localization of ανβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

    Giovanni Latella, Antonella Vetuschi, Roberta Sferra, Silvia Speca, Eugenio Gaudio
    13-10-2025
    https://doi.org/10.4081/ejh.2025.4428
    377
    PDF: 454
    HTML: 49
  • A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer

    Daniëlle Krijgsman, Ronald L.P. van Vlierberghe, Vaios Evangelou, Alexander L. Vahrmeijer, Cornelis J.H. van de Velde, Cornelis F.M. Sier, Peter J.K. Kuppen
    20-05-2019
    https://doi.org/10.4081/ejh.2019.3028
    1761
    PDF: 906
    Supplementary: 273
    HTML: 54
  • Downregulation of GMPS inhibited the proliferation of hepatocellular cancer cells via the regulation of STAT3/c-Myc pathway

    Zhibin Guo, Juan Yu, Jing Sun, Sheng Yang, Jiang Pu
    15-06-2026
    https://doi.org/10.4081/ejh.2026.4541
    260
    PDF: 300
    Supplementary: 78
    HTML: 36
  • Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study

    A. Santoro, G. Pannone, M.E. Errico, D. Bifano, G. Lastilla, P. Bufo, C. Loreto, V. Donofrio
    e25
    02-07-2012
    https://doi.org/10.4081/ejh.2012.e25
    1692
    PDF: 784
    HTML: 5510
  • Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

    A.M. Schläfli, S. Berezowska, O. Adams, R. Langer, M.P. Tschan
    05-05-2015
    https://doi.org/10.4081/ejh.2015.2481
    9464
    PDF: 3506
    HTML: 2213
  • Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

    Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou
    02-12-2021
    https://doi.org/10.4081/ejh.2021.3331
    2874
    PDF: 1653
    HTML: 73
  • Co-expression of MyHC-15 with other known isoforms in rat muscle spindles

    Vika Smerdu, Chiedozie Kenneth Ugwoke, Žiga Šink
    24-03-2025
    https://doi.org/10.4081/ejh.2025.4192
    1611
    PDF: 475
    HTML: 60
  • Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

    Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li
    17-05-2023
    https://doi.org/10.4081/ejh.2023.3612
    1757
    PDF: 1055
    Supplementary: 146
    HTML: 54
  • Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

    Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2749
    6265
    PDF: 1475
    HTML: 440
  • Fluorescence properties of the Na+/H+exchanger inhibitor HMA (5-(N,N-hexamethylene)amiloride) are modulated by intracellular pH

    V. Giansanti, G. Santamaria, A. Torriglia, F. Aredia, A.I. Scovassi, G. Bottiroli, A.C. Croce
    e3
    20-01-2012
    https://doi.org/10.4081/ejh.2012.e3
    1803
    PDF: 771
    HTML: 2936
  • miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

    Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4161
    1796
    PDF: 602
    HTML: 73
  • Muc5ac mucin expression during rat skin development

    V. Ferretti, Á. Segal-Eiras, C.G. Barbeito, M.V. Croce
    20-02-2015
    https://doi.org/10.4081/ejh.2015.2462
    2699
    PDF: 954
    HTML: 749
  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2453
    PDF: 1396
    Supplementary: 192
    HTML: 303
  • Lysosomal labelling with mouse anti-human LAMP-1 antibody (green) shows that the autofluorescent material (red) is located within LAMP-1 positive vesicles (arrow heads)

    Autofluorescence in freshly isolated adult human liver sinusoidal cells

    Anett Kristin Larsen, Jaione Simón-Santamaría, Kjetil Elvevold, Bo Göran Ericzon, Kim Erlend Mortensen, Peter McCourt, Bård Smedsrød, Karen Kristine Sørensen
    13-12-2021
    https://doi.org/10.4081/ejh.2021.3337
    2641
    PDF: 1070
    HTML: 101
  • Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner

    Jana Oswald, Maximilian Büttner, Simon Jasinski-Bergner, Roland Jacobs, Philip Rosenstock, Heike Kielstein
    26-01-2018
    https://doi.org/10.4081/ejh.2018.2848
    3582
    PDF: 1326
    HTML: 153
  • Decellularized omentum as novel biologic scaffold for reconstructive surgery and regenerative medicine

    A. Porzionato, M. M. Sfriso, V. Macchi, A. Rambaldo, G. Lago, L. Lancerotto, V. Vindigni, R. De Caro
    e4
    24-01-2013
    https://doi.org/10.4081/ejh.2013.e4
    2637
    PDF: 1262
    HTML: 1125
  • ADVANCEMENTS AND EMERGING PERSPECTIVES IN MICROSCOPIC IMAGING S. Karahuseyinoglu | Department of Histology & Embryology, Koc University, School of Medicine, Istanbul, Turkiye

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4307
    379
  • Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

    Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai
    14-10-2022
    https://doi.org/10.4081/ejh.2022.3510
    1545
    PDF: 790
    HTML: 72
  • Developmental characteristics of cutaneous telocytes in late embryos of the silky fowl

    Hao Li, Junliang Chen, Wenjun You, Yizhen Xu, Yaqiong Ye, Haiquan Zhao, Junxing Li, Hui Zhang
    15-10-2024
    https://doi.org/10.4081/ejh.2024.4089
    1903
    PDF: 513
    HTML: 49
  • Deleted in Liver Cancer 2 (DLC2) protein expression in hepatocellular carcinoma

    Dominika Wolosz, Agnieszka Walczak, Grzegorz Szparecki, Michal Dwojak, Magdalena Winiarska, Ewa Wolinska, Barbara Gornicka
    18-02-2019
    https://doi.org/10.4081/ejh.2019.2981
    1633
    PDF: 862
    HTML: 65
  • Immunohistochemical/histochemical double staining method in the study of the columnar metaplasia of the oesophagus

    D. Cabibi, A.G. Giannone, C. Mascarella, C. Guarnotta, M. Castiglia, G. Pantuso, E. Fiorentino
    05-03-2014
    https://doi.org/10.4081/ejh.2014.2326
    2679
    PDF: 1223
    HTML: 1145
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    3321
    PDF: 1860
    Video 1: 334
    Video 2: 378
    HTML: 54
  • RXRα is upregulated in first trimester endometrial glands of spontaneous abortions unlike LXR and PPARγ

    J. Knabl, A. Vattai, R. Hüttenbrenner, S. Hutter, M. Karsten, U. Jeschke
    02-11-2016
    https://doi.org/10.4081/ejh.2016.2665
    2389
    PDF: 1191
    HTML: 353
  • Intracellular distribution of Tankyrases as detected by multicolor immunofluorescence techniques

    M.G. Bottone, G. Santin, C. Soldani, P. Veneroni, A.I. Scovassi, C. Alpini
    e4
    20-01-2012
    https://doi.org/10.4081/ejh.2012.e4
    1544
    PDF: 783
    HTML: 5242
  • Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

    Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera
    20-04-2022
    https://doi.org/10.4081/ejh.2022.3409
    2001
    PDF: 1085
    HTML: 67
  • The substance P and neurokinin-1 receptor system in human thyroid cancer: an immunohistochemical study

    Inmaculada Isorna, Francisco Esteban, Juan Solanellas, Rafael Coveñas, Miguel Muñoz
    28-04-2020
    https://doi.org/10.4081/ejh.2020.3117
    1523
    PDF: 812
    HTML: 42
  • Immunocytochemical detection of dentin matrix proteins in primary teeth from patients with dentinogenesis imperfecta associated with osteogenesis imperfecta

    G. Orsini, A. Majorana, A. Mazzoni, A. Putignano, M. Falconi, A. Polimeni, L. Breschi
    01-12-2014
    https://doi.org/10.4081/ejh.2014.2405
    2435
    PDF: 1423
    HTML: 580
  • Immunohistochemical expression of HGF, c-MET and transcription factor STAT3 in colorectal tumors

    M Trovato, E Vitarelli, M Grosso, S Alesci, S Benvenga, F Trimarchi, G Barresi
    291-298
    29-06-2009
    https://doi.org/10.4081/898
    727
    Untitled: 0
    PDF: 1590
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European Journal of Histochemistry

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