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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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3.7
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1.9
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3.7
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  • RXRα is upregulated in first trimester endometrial glands of spontaneous abortions unlike LXR and PPARγ

    J. Knabl, A. Vattai, R. Hüttenbrenner, S. Hutter, M. Karsten, U. Jeschke
    02-11-2016
    https://doi.org/10.4081/ejh.2016.2665
    2247
    PDF: 1131
    HTML: 325
  • Intracellular distribution of Tankyrases as detected by multicolor immunofluorescence techniques

    M.G. Bottone, G. Santin, C. Soldani, P. Veneroni, A.I. Scovassi, C. Alpini
    e4
    20-01-2012
    https://doi.org/10.4081/ejh.2012.e4
    1466
    PDF: 728
    HTML: 5236
  • Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

    Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera
    20-04-2022
    https://doi.org/10.4081/ejh.2022.3409
    1890
    PDF: 1007
    HTML: 33
  • The substance P and neurokinin-1 receptor system in human thyroid cancer: an immunohistochemical study

    Inmaculada Isorna, Francisco Esteban, Juan Solanellas, Rafael Coveñas, Miguel Muñoz
    28-04-2020
    https://doi.org/10.4081/ejh.2020.3117
    1438
    PDF: 753
    HTML: 15
  • Immunocytochemical detection of dentin matrix proteins in primary teeth from patients with dentinogenesis imperfecta associated with osteogenesis imperfecta

    G. Orsini, A. Majorana, A. Mazzoni, A. Putignano, M. Falconi, A. Polimeni, L. Breschi
    01-12-2014
    https://doi.org/10.4081/ejh.2014.2405
    2295
    PDF: 1327
    HTML: 553
  • Immunohistochemical expression of HGF, c-MET and transcription factor STAT3 in colorectal tumors

    M Trovato, E Vitarelli, M Grosso, S Alesci, S Benvenga, F Trimarchi, G Barresi
    291-298
    29-06-2009
    https://doi.org/10.4081/898
    677
    Untitled: 0
    PDF: 1561
  • Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity

    Bita Moudi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Seyed-Moayed Alavian, Kamran B. Lankarani, Parisa Farrokh, Jens Randel Nyengaard
    29-01-2018
    https://doi.org/10.4081/ejh.2018.2859
    2400
    PDF: 1111
    HTML: 84
  • BIOLOGICAL RESPONSE OF TREATMENT WITH SAFFRON PETAL EXTRACT ON CYTOKYNE-INDUCED OXIDATIVE STRESS AND INFLAMMATION IN THE CACO-2/THP1 COCOLTURE MODEL V. Panella1, F. De Cecco2, S. Franceschelli1, M. A. Maggi3, S. Bisti4, A. Bravo Nuevo5, D. D’Ardes1, F. Cipollone1, L. Speranza1 | 1Department of Medicine and Aging Sciences, University «G. D’Annunzio», Chieti; 2Italian Institute of Technology, Genoa, Italy; 3Hortus Novus, L’Aquila, Italy; 4National Institute of Biostructure and Biosystem, Rome, Italy; 5Department of Biomedical Sciences, Philadelphia College of Osteopathic Medicine (PCOM), Philadelphia, USA

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4320
    343
  • Chemotherapy-induced nephrotoxicity was improved by crocin in mouse model

    Qichao Yin, Hua Xiong
    03-10-2022
    https://doi.org/10.4081/ejh.2022.3541
    1143
    PDF: 720
    HTML: 47
  • Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma

    Romina Mancinelli, Antimo Cutone, Luigi Rosa, Maria Stefania Lepanto, Paolo Onori, Luigi Pannarale, Antonio Franchitto, Eugenio Gaudio, Piera Valenti
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3156
    1808
    PDF: 810
    HTML: 26
  • Immunoreactivity of thymosin beta 4 in human foetal and adult genitourinary tract

    S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, D. Fanni, C. Gerosa, B. Manconi, I. Messana, M. Castagnola, G. Faa
    e43
    13-10-2010
    https://doi.org/10.4081/ejh.2010.e43
    1539
    PDF: 616
    HTML: 998
  • Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

    Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin
    23-10-2024
    https://doi.org/10.4081/ejh.2024.4098
    2606
    PDF: 549
    HTML: 39
  • Downregulation of Williams syndrome transcription factor (WSTF) suppresses glioblastoma cell growth and invasion by inhibiting PI3K/AKT signal pathway

    Liyuan Yang, Chunfu Du, Hui Chen, Zhengwen Diao
    17-11-2021
    https://doi.org/10.4081/ejh.2021.3255
    1299
    PDF: 689
    HTML: 51
  • VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas

    Ana Silvia Corlan, Anca Maria Cîmpean, Eugen Melnic, Marius Raica, Simona Sarb
    05-03-2019
    https://doi.org/10.4081/ejh.2019.3010
    1730
    PDF: 840
    HTML: 28
  • Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

    Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3639
    1338
    PDF: 801
    HTML: 28
  • Mena, a new available marker in tumors of salivary glands?

    S. Gurzu, M. Krause, I. Ember, L. Azamfirei, G. Gobel, K. Feher, I. Jung
    e8
    07-02-2012
    https://doi.org/10.4081/ejh.2012.e8
    1455
    PDF: 730
    HTML: 4182
  • The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin

    S Pucci, E Bonanno, F Pichiorri, P Mazzarelli, LG Spagnoli
    103-110
    29-06-2009
    https://doi.org/10.4081/873
    792
    PDF: 788
  • P10 | BIOLOGICAL ACTIVITIES OF CITRUS LIMON-, VITIS VINIFERA- AND ACTINIDIA DELICIOSA-DERIVED EXTRACELLULAR VESICLES ON HUMAN CACO-2 CELLS M. Destino, E. Carata, B.A. Tenuzzo, E. Panzarini | Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4706
    104
    PDF: 38
  • Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

    Jiapei Lv, Wang Yanting, Shan Wei
    08-11-2023
    https://doi.org/10.4081/ejh.2023.3867
    2175
    PDF: 1089
    HTML: 63
  • Expression patterns of α2,3-Sialyltransferase I and α2,6-Sialyltransferase I in human cutaneous epithelial lesions

    S.A. Ferreira, J.L.A. Vasconcelos, R.C.W.C. Silva, C.L.B. Cavalcanti, C.L. Bezerra, M.J.B.M. Rêgo, E.I.C. Beltrão
    e7
    14-02-2013
    https://doi.org/10.4081/ejh.2013.e7
    1612
    PDF: 810
    HTML: 239
  • Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi
    23-06-2022
    https://doi.org/10.4081/ejh.2022.3377
    1869
    PDF: 1007
    HTML: 29
  • Swertiamarin suppresses proliferation, migration, and invasion of hepatocellular carcinoma cells via negative regulation of FRAT1

    Shufeng Xiao, Haoren Tang, Yao Bai, Renchao Zou, Zongfang Ren, Xuesong Wu, Zhitian Shi, Song Lan, Wei Liu, Tiangen Wu, Cheng Zhang, Lin Wang
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3169
    1603
    PDF: 796
    HTML: 36
  • Alarin regulates RyR2 and SERCA2 to improve cardiac function in heart failure with preserved ejection fraction

    Jinshuang Li, Dawei Xu, Ce Shi, Chunqi Cheng, Ziheng Xu, Xingjuan Gao, Yong Cheng
    28-10-2024
    https://doi.org/10.4081/ejh.2024.4122
    1627
    PDF: 641
    HTML: 24
  • LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma

    Nuobei Zhang, Hao Shen, Shenan Huang, Fenfen Wang, Huifang Liu, Fen Xie, Lei Jiang, Xin Chen
    16-11-2021
    https://doi.org/10.4081/ejh.2021.3300
    1374
    PDF: 731
    HTML: 56
  • Expression pattern of thymosin beta 4 in the adult human liver

    S. Nemolato, P. Van Eyken, T. Cabras, F. Cau, M.U. Fanari, A. Locci, D. Fanni, C.L.P. Gerosa, I. Messana, M. Castagnola, G. Faa
    e25
    07-09-2011
    https://doi.org/10.4081/ejh.2011.e25
    1654
    PDF: 741
    HTML: 1415
  • 24 | ADMINISTRATION OF BRANCHED-CHAIN AMINO ACIDS AND DI-ALANINE MITIGATES MUSCLE ATROPHY IN A MOUSE MODEL OF CANCER CACHEXIA M. Colardo1, N. Martella1, M. Varone1, D. Pensabene1, G. Caretti2, G. Bianchini3, A. Aramini3, M. Segatto1 | 1Dept. of Biosciences and Territory, University of Molise, Italy; 2Dept. of Biosciences, University of Milan, Italy; 3Research & Early Development, Dompé Farmaceutici S.p.A., L’Aquila, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4642
    124
    PDF: 54
  • SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

    Yiyu Qin, Jian Li, Hongchao Han, Yongliang Zheng, Haiming Lei, Yang Zhou, Hongyan Wu, Guozhe Zhang, Xiang Chen, Zhengping Chen
    28-12-2023
    https://doi.org/10.4081/ejh.2023.3899
    1218
    PDF: 395
    HTML: 12
  • Detection and characterisation of NAD(P)H-diaphorase activity in Dictyostelium discoideum cells (Protozoa)

    A. Amaroli, M.G. Chessa
    e47
    29-10-2012
    https://doi.org/10.4081/ejh.2012.e47
    1560
    PDF: 696
    HTML: 532
  • P79 | AN INNOVATIVE FUNCTIONAL COOKIE MODULATES THE MUCOSA AND MYENTERIC PLEXUS IN THE GUT OF 3xTg-AD MOUSE MODEL OF ALZHEIMER’S DISEASE V. Bellitto1, F. Grasselli1, L. Lucernoni1, I. Martinelli2, E. Vittadini1, A.M. Eleuteri1, L. Bonfili1, S.K. Tayebati2, D. Tomassoni1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal Sciences and Health Products, University of Camerino, Camerino, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4405
    311
  • Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

    Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou
    22-06-2022
    https://doi.org/10.4081/ejh.2022.3394
    2135
    PDF: 1393
    HTML: 32
  • Twenty years of histochemistry in the third millennium, browsing the scientific literature

    Carlo Pellicciari
    29-12-2020
    https://doi.org/10.4081/ejh.2020.3213
    1455
    PDF: 566
    HTML: 17
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1799
    PDF: 293
    HTML: 35
  • Neurokinin-1 receptor is highly expressed in cervical cancer and its antagonist induces cervical cancer cell apoptosis

    Liyun Guan, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang
    11-01-2023
    https://doi.org/10.4081/ejh.2023.3570
    1566
    PDF: 746
    HTML: 43
  • Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma

    Lulu Le, Ji Luo, Haifang Wu, Ling Chen, Xiaoli Tang, Fen Fu
    30-03-2021
    https://doi.org/10.4081/ejh.2021.3226
    2173
    PDF: 932
    Supplementary: 207
    HTML: 34
  • Histochemical properties of sialic acids and antimicrobial substances in canine anal glands

    T. Nara, T. Yasui, O. Fujimori, W. Meyer, A. Tsukise
    e29
    15-09-2011
    https://doi.org/10.4081/ejh.2011.e29
    1984
    PDF: 732
    HTML: 3459
  • Downregulation of SRPK2 promotes cell cycle arrest though E2F1 in non-small cell lung cancer

    Xin Li, Shaoyu Yang, Minna Zhang, Shuhuan Xie, Zefeng Xie
    11-12-2019
    https://doi.org/10.4081/ejh.2019.3067
    2151
    PDF: 1169
    HTML: 25
  • 12 | IMPACT OF COCAINE ON GASTROINTESTINAL BARRIER INTEGRITY S. Boccia1, B. Sgangarella Valvano2, A. Mileo3, A. Nebbioso4, A. De Luca1, A. Capaldo5, M. De Falco5|6 | 1Dept. of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; 2Dept. of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy; 3Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; 4Dept. of Precision Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; 5Dept. of Biology, University of Naples Federico II, Naples, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4630
    209
    PDF: 56
  • Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

    Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng
    03-09-2021
    https://doi.org/10.4081/ejh.2021.3264
    2079
    PDF: 779
    Supplementary: 159
    HTML: 33
  • MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices

    Elena Casiraghi, Mara Cossa, Veronica Huber, Licia Rivoltini, Matteo Tozzi, Antonello Villa, Barbara Vergani
    02-11-2017
    https://doi.org/10.4081/ejh.2017.2838
    2551
    PDF: 1248
    MIAQuant user Manual: 288
    MIAQuant source code: 367
    HTML: 80
  • P85 | ALTERATION OF SUBMUCOSAL AND MYENTERIC GANGLIA IN SEVERE GUT DYSMOTILITY: A QUANTITATIVE MORPHOMETRIC ANALYSIS H. Yaghi1, E. Boschetti1, S. Blando1, I. Neri1, C. Malagelada2, R. De Giorgio3, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Bologna, Italy; 2Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; 3Department of Translational Medicine, Università di Ferrara, Ferrara, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4411
    301
  • Distribution of alpha-synuclein in normal human jejunum and its relations with the chemosensory and neuroendocrine system

    Arianna Casini, Romina Mancinelli, Caterina Loredana Mammola, Luigi Pannarale, Piero Chirletti, Paolo Onori, Rosa Vaccaro
    02-11-2021
    https://doi.org/10.4081/ejh.2021.3310
    3000
    PDF: 1253
    HTML: 87
  • Marine bisindole alkaloid: A potential apoptotic inducer in human cancer cells

    Sara Salucci, Sabrina Burattini, Francesca Buontempo, Ester Orsini, Lucia Furiassi, Michele Mari, Simone Lucarini, Alberto M. Martelli, Elisabetta Falcieri
    10-04-2018
    https://doi.org/10.4081/ejh.2018.2881
    2938
    PDF: 1039
    HTML: 65
  • Erratum - Localization of ανβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

    Giovanni Latella, Antonella Vetuschi, Roberta Sferra, Silvia Speca, Eugenio Gaudio
    13-10-2025
    https://doi.org/10.4081/ejh.2025.4428
    296
    PDF: 219
    HTML: 12
  • A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer

    Daniëlle Krijgsman, Ronald L.P. van Vlierberghe, Vaios Evangelou, Alexander L. Vahrmeijer, Cornelis J.H. van de Velde, Cornelis F.M. Sier, Peter J.K. Kuppen
    20-05-2019
    https://doi.org/10.4081/ejh.2019.3028
    1694
    PDF: 834
    Supplementary: 233
    HTML: 23
  • Downregulation of GMPS inhibited the proliferation of hepatocellular cancer cells via the regulation of STAT3/c-Myc pathway

    Zhibin Guo, Juan Yu, Jing Sun, Sheng Yang, Jiang Pu
    15-06-2026
    https://doi.org/10.4081/ejh.2026.4541
    166
    PDF: 175
    Supplementary: 31
    HTML: 7
  • Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study

    A. Santoro, G. Pannone, M.E. Errico, D. Bifano, G. Lastilla, P. Bufo, C. Loreto, V. Donofrio
    e25
    02-07-2012
    https://doi.org/10.4081/ejh.2012.e25
    1614
    PDF: 693
    HTML: 5494
  • Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

    A.M. Schläfli, S. Berezowska, O. Adams, R. Langer, M.P. Tschan
    05-05-2015
    https://doi.org/10.4081/ejh.2015.2481
    9146
    PDF: 3400
    HTML: 2177
  • Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

    Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou
    02-12-2021
    https://doi.org/10.4081/ejh.2021.3331
    2701
    PDF: 1580
    HTML: 42
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Vol. 70 No. 2 (2026)
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European Journal of Histochemistry

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