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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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3.7
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1.9
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3.7
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  • Histochemistry as a versatile research toolkit in biological research, not only an applied discipline in pathology

    Carlo Pellicciari
    21-12-2018
    https://doi.org/10.4081/ejh.2018.3006
    2161
    PDF: 817
    HTML: 28
  • Infection with CagA-positive Helicobacter pylori strain containing three EPIYA C phosphorylation sites is associated with more severe gastric lesions in experimentally infected Mongolian gerbils (Meriones unguiculatus)

    M. Ferreira Júnior, S.A. Batista, P.V.T. Vidigal, A.A.C. Cordeiro, F.M.S. Oliveira, L.O. Prata, A.E.T. Diniz, C.M. Barral, R.C. Barbuto, A.D. Gomes, I.D. Araújo, D.M.M. Queiroz, M.V. Caliari
    27-04-2015
    https://doi.org/10.4081/ejh.2015.2489
    2211
    PDF: 805
    Supplementary: 326
    HTML: 567
  • A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer

    Daniëlle Krijgsman, Ronald L.P. van Vlierberghe, Vaios Evangelou, Alexander L. Vahrmeijer, Cornelis J.H. van de Velde, Cornelis F.M. Sier, Peter J.K. Kuppen
    20-05-2019
    https://doi.org/10.4081/ejh.2019.3028
    1667
    PDF: 786
    Supplementary: 218
    HTML: 21
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1591
    PDF: 260
    HTML: 25
  • Quantification of morphology of canine circumanal gland tumors: a fractal based study

    I.C. Šoštarić-Zuckermann, K. Severin, M. Huzak, M. Hohšteter, A. Gudan Kurilj, B. Artuković, A. Džaja, Ž. Grabarević
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2609
    1927
    PDF: 733
    HTML: 382
  • High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

    Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari
    16-12-2024
    https://doi.org/10.4081/ejh.2024.4145
    1425
    PDF: 588
    HTML: 9
  • Elevated caspase 3 expression correlates with severe inflammation in Crohn’s disease

    Nafie Sejdiu, Michael Naumann, Michael Vieth
    03-06-2026
    https://doi.org/10.4081/ejh.2026.4570
    171
    PDF: 120
    HTML: 8
  • Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study

    A. Santoro, G. Pannone, M.E. Errico, D. Bifano, G. Lastilla, P. Bufo, C. Loreto, V. Donofrio
    e25
    02-07-2012
    https://doi.org/10.4081/ejh.2012.e25
    1583
    PDF: 653
    HTML: 5417
  • Two histological methods for recognition and study of cortical microinfarcts in thick sections

    Heiko Braak, Simone Feldengut, Jan Kassubek, Deniz Yilmazer-Hanke, Kelly Del Tredici
    20-12-2018
    https://doi.org/10.4081/ejh.2018.2989
    2255
    PDF: 894
    HTML: 30
  • Pleural mesothelioma from fluoro-edenite exposure: PACAP and PAC1 receptor. A preliminary report

    Claudia Lombardo, Grazia Maugeri, Agata Grazia D'Amico, Giuseppe Broggi, Rosario Caltabiano, Veronica Filetti, Serena Matera, Velia D'Agata, Carla Loreto
    02-05-2024
    https://doi.org/10.4081/ejh.2024.3994
    1623
    PDF: 526
    HTML: 33
  • Successful triple immunoenzymatic method employing primary antibodies from same species and same immunoglobulin subclass

    T. A. Osman, G. Øijordsbakken, D. E. Costea, A. C. Johannessen
    e22
    16-09-2013
    https://doi.org/10.4081/ejh.2013.e22
    3254
    PDF: 899
    HTML: 2122
  • Defense and protection mechanisms in lung exposed to asbestiform fiber: the role of macrophage migration inhibitory factor and heme oxygenase-1

    Carla Loreto, Rosario Caltabiano, Adriana Carol Eleonora Graziano, Sergio Castorina, Claudia Lombardo, Vera Filetti, Ermanno Vitale, Giuseppe Rapisarda, Venera Cardile, Caterina Ledda, Venerando Rapisarda
    16-04-2020
    https://doi.org/10.4081/ejh.2020.3073
    1427
    PDF: 839
    HTML: 22
  • MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices

    Elena Casiraghi, Mara Cossa, Veronica Huber, Licia Rivoltini, Matteo Tozzi, Antonello Villa, Barbara Vergani
    02-11-2017
    https://doi.org/10.4081/ejh.2017.2838
    2509
    PDF: 1219
    MIAQuant user Manual: 268
    MIAQuant source code: 344
    HTML: 77
  • Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study

    M. Di Rosa, M.A. Szychlinska, D. Tibullo, L. Malaguarnera, G. Musumeci
    16-09-2014
    https://doi.org/10.4081/ejh.2014.2423
    3034
    PDF: 1203
    HTML: 1611
  • Distribution of alpha-synuclein in normal human jejunum and its relations with the chemosensory and neuroendocrine system

    Arianna Casini, Romina Mancinelli, Caterina Loredana Mammola, Luigi Pannarale, Piero Chirletti, Paolo Onori, Rosa Vaccaro
    02-11-2021
    https://doi.org/10.4081/ejh.2021.3310
    2932
    PDF: 1197
    HTML: 82
  • High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

    Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos
    17-02-2022
    https://doi.org/10.4081/ejh.2022.3360
    2653
    PDF: 1017
    HTML: 44
  • Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor

    Antonio Franchitto, Diletta Overi, Romina Mancinelli, Anna Paola Mitterhofer, Paolo Muiesan, Francesca Tinti, Ilaria Umbro, Stefan G. Hubscher, Paolo Onori, Eugenio Gaudio, Guido Carpino
    10-05-2019
    https://doi.org/10.4081/ejh.2019.3022
    2511
    PDF: 798
    Supplementary: 285
    HTML: 17
  • 3-hydroxi-anthranilic acid is early expressed in stroke

    A. Mangas, J. Yajeya, N. González, I. Ruiz, M. Geffard, R. Coveñas
    02-12-2016
    https://doi.org/10.4081/ejh.2016.2709
    2358
    PDF: 720
    HTML: 311
  • Mena, a new available marker in tumors of salivary glands?

    S. Gurzu, M. Krause, I. Ember, L. Azamfirei, G. Gobel, K. Feher, I. Jung
    e8
    07-02-2012
    https://doi.org/10.4081/ejh.2012.e8
    1435
    PDF: 709
    HTML: 4128
  • NO-tryptophan: a new small molecule located in the rat brain

    A. Mangas, J. Yajeya, N. González, S. Duleu, M. Geffard, R. Coveñas
    22-09-2016
    https://doi.org/10.4081/ejh.2016.2692
    2099
    PDF: 591
    HTML: 245
  • Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

    M. Costanzo, B. Cisterna, A. Vella, T. Cestari, V. Covi, G. Tabaracci, M. Malatesta
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2515
    3140
    PDF: 1022
    HTML: 413
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    285
    PDF: 385
    HTML: 9
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2737
    PDF: 1047
    HTML: 156
  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    516
    PDF: 323
    Raw data: 42
    HTML: 17
  • Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour

    W. Meyer, M. Liumsiricharoen, A. Suprasert, L.G. Fleischer, M. Hewicker-Trautwein
    e27
    16-09-2013
    https://doi.org/10.4081/ejh.2013.e27
    3544
    PDF: 1206
    HTML: 523
  • FROM CLOUD TO BEDSIDE C. Tacchetti1,2 | 1Medical School & S.RACE (San-Raffaele Artificial Intelligence Center);Vita-Salute University San Raffaele, Milan, Italy; 2Experimental Imaging Center, IRCCS Hospital San Raffaele, Milan, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4294
    209
  • Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1

    S. Iachettini, R. Valaperta, A. Marchesi, A. Perfetti, G. Cuomo, B. Fossati, L. Vaienti, E. Costa, G. Meola, R. Cardani
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2562
    2069
    PDF: 954
    HTML: 394
  • Effect of high-fat mixed lipid diet and swimming on fibre types in skeletal muscles of rats with colon tumours

    Vika Smerdu, Martina Perše
    25-07-2018
    https://doi.org/10.4081/ejh.2018.2945
    1965
    PDF: 772
    HTML: 51
  • Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

    V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas
    e5
    08-02-2011
    https://doi.org/10.4081/ejh.2011.e5
    1511
    PDF: 806
    HTML: 3471
  • Bile duct ligature in young rats: A revisited animal model for biliary atresia

    Matias Garrido, Camila Escobar, Constanza Zamora, Carolina Rejas, Juan Varas, Mario Párraga, Sebastián San Martin, Sandra Montedonico
    13-09-2017
    https://doi.org/10.4081/ejh.2017.2803
    2108
    PDF: 972
    HTML: 157
  • The penetration of methanol into bovine cardiac and hepatic tissues is faster than ethanol and formalin

    Michelle Steicke, Guang Yang, Tam Nguyen Dinh, Matthew Dunster-Jones, Owen Sargisson, Farah Ahmady, Jonathan Golledge, Yutang Wang
    07-02-2018
    https://doi.org/10.4081/ejh.2018.2880
    2065
    PDF: 842
    Supplementary: 207
    HTML: 53
  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2282
    PDF: 1204
    Supplementary: 111
    HTML: 174
  • Evolutionary intraembryonic origin of vertebrate hematopoietic stem cells in the elasmobranch spleen

    Rosa Manca, Chester A. Glomski, Alessandra Pica
    20-12-2018
    https://doi.org/10.4081/ejh.2018.2987
    1690
    PDF: 687
    HTML: 33
  • Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

    D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev
    05-08-2015
    https://doi.org/10.4081/ejh.2015.2530
    2832
    PDF: 930
    HTML: 1389
  • Developmental characteristics of cutaneous telocytes in late embryos of the silky fowl

    Hao Li, Junliang Chen, Wenjun You, Yizhen Xu, Yaqiong Ye, Haiquan Zhao, Junxing Li, Hui Zhang
    15-10-2024
    https://doi.org/10.4081/ejh.2024.4089
    1767
    PDF: 402
    HTML: 15
  • DNA damage in acute myeloid leukemia patients of Northern Mexico

    Martha I. Dávila-Rodríguez, Elva I. Cortés-Gutiérrez, Roberto Hernández-Valdés, Karla Guzmán-Cortés, Rosa E. De León-Cantú, Ricardo M. Cerda-Flores, Enrique Báez-De la Fuente
    11-12-2017
    https://doi.org/10.4081/ejh.2017.2851
    1749
    PDF: 584
    HTML: 141
  • Ultrastructure of telocytes, a new type of interstitial cells in the myocardium of the Chinese giant salamander (Andrias davidianus)

    Tingting Ge, Yaqiong Ye, Hui Zhang
    23-05-2019
    https://doi.org/10.4081/ejh.2019.3021
    1800
    PDF: 856
    HTML: 14
  • Porcine intestinal mast cells. Evaluation of different fixatives for histochemical staining techniques considering tissue shrinkage

    J. Rieger, S. Twardziok, H. Huenigen, R. M. Hirschberg, J. Plendl
    e21
    30-07-2013
    https://doi.org/10.4081/ejh.2013.e21
    4311
    PDF: 1173
    HTML: 1301
  • Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

    Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié
    21-08-2025
    https://doi.org/10.4081/ejh.2025.4174
    627
    PDF: 431
    HTML: 24
  • Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

    Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan
    13-05-2024
    https://doi.org/10.4081/ejh.2024.3917
    2045
    PDF: 861
    HTML: 50
  • Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study

    Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi
    31-07-2018
    https://doi.org/10.4081/ejh.2018.2956
    2012
    PDF: 994
    Supplementary: 211
    HTML: 48
  • Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma

    Chiara Rita Inguscio, Barbara Cisterna, Maria Assunta Lacavalla, Franco Donati, Osvaldo Angelini, Gabriele Tabaracci, Manuela Malatesta
    10-10-2023
    https://doi.org/10.4081/ejh.2023.3879
    4700
    PDF: 798
    HTML: 27
  • Mast cells in meningiomas

    Antonio D'Amati, Roberto Tamma, Tiziana Annese, Anna Rizzi, Domenico Ribatti
    18-04-2024
    https://doi.org/10.4081/ejh.2024.3973
    1538
    PDF: 459
    HTML: 27
  • Localization of peripheral autonomic neurons innervating the boar urinary bladder trigone and neurochemical features of the sympathetic component

    L. Ragionieri, M. Botti, F. Gazza, C. Sorteni, R. Chiocchetti, P. Clavenzani, L. Bo, R. Panu
    e16
    06-05-2013
    https://doi.org/10.4081/ejh.2013.e16
    2528
    PDF: 1200
    HTML: 1040
  • Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma

    Romina Mancinelli, Antimo Cutone, Luigi Rosa, Maria Stefania Lepanto, Paolo Onori, Luigi Pannarale, Antonio Franchitto, Eugenio Gaudio, Piera Valenti
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3156
    1766
    PDF: 773
    HTML: 24
  • Dark-field microscopy enhance visibility of CD31 endothelial staining

    Eva Jennische, Stefan Lange, Ragnar Hultborn
    01-07-2020
    https://doi.org/10.4081/ejh.2020.3133
    1596
    PDF: 783
    HTML: 15
  • Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

    Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4218
    1504
    PDF: 591
    HTML: 30
  • Muscleblind-like1 undergoes ectopic relocation in the nuclei of skeletal muscles in myotonic dystrophy and sarcopenia

    M. Malatesta, M. Giagnacovo, M. Costanzo, B. Cisterna, R. Cardani, G. Meola
    e15
    22-04-2013
    https://doi.org/10.4081/ejh.2013.e15
    2982
    PDF: 4336
    HTML: 469
  • Antigen retrieval pre-treatment causes a different expression pattern of Cav3.2 in rat and mouse spinal dorsal horn

    Xiao E Cheng, Long Xian Ma, Xiao Jin Feng, Meng Ye Zhu, Da Ying Zhang, Lin Lin Xu, Tao Liu
    23-01-2019
    https://doi.org/10.4081/ejh.2019.2988
    2105
    PDF: 880
    Supplementary: 229
    HTML: 38
  • Calcium-induced alteration of mitochondrial morphology and mitochondrial-endoplasmic reticulum contacts in rat brown adipocytes

    I. Golic, K. Velickovic, M. Markelic, A. Stancic, A. Jankovic, M. Vucetic, V. Otasevic, B. Buzadzic, B. Korac, A. Korac
    09-09-2014
    https://doi.org/10.4081/ejh.2014.2377
    3464
    PDF: 1184
    HTML: 1548
  • Histochemical localization of sialic acids and antimicrobial substances in eccrine glands of porcine snout skin

    K. Fukui, T. Yasui, H. Gomi, H. Sugiya, O. Fujimori, W. Meyer, A. Tsukise
    e6
    09-02-2012
    https://doi.org/10.4081/ejh.2012.e6
    1876
    PDF: 864
    HTML: 6710
  • The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model

    Roman M. Kassa, Roberta Bonafede, Federico Boschi, Manuela Malatesta, Raffaella Mariotti
    17-05-2018
    https://doi.org/10.4081/ejh.2018.2904
    2135
    PDF: 744
    HTML: 32
  • Immunohistochemical study of doublecortin and nucleostemin in canine brain

    E. De Nevi, P. Marco-Salazar, D. Fondevila, E. Blasco, L. Pérez, M. Pumarola
    e9
    20-03-2013
    https://doi.org/10.4081/ejh.2013.e9
    2643
    PDF: 740
    HTML: 283
  • Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells in vitro

    Xilin Ge, Caoxin Huang, Wenting Chen, Chen Yang, Wenfang Huang, Jia Li, Shuyu Yang
    25-11-2024
    https://doi.org/10.4081/ejh.2024.4140
    2090
    PDF: 667
    HTML: 32
  • Expression of hyaluronan synthase 3 in deformed human temporomandibular joint discs: in vivo and in vitro studies

    T. Matsumoto, M. Inayama, I. Tojyo, N. Kiga, S. Fujita
    e50
    15-12-2010
    https://doi.org/10.4081/ejh.2010.e50
    1720
    PDF: 709
    HTML: 1304
  • Postsynaptic cleft density changes with combined exercise protocols in an experimental model of muscular hypertrophy

    Jurandyr Pimentel Neto, Lara Caetano Rocha, Carolina dos Santos Jacob, Gabriela Klein Barbosa, Adriano Polican Ciena
    04-08-2021
    https://doi.org/10.4081/ejh.2021.3274
    1352
    PDF: 580
    HTML: 23
  • Histochemistry and immunolocalisation of glucokinin in antidiabetic plants used in traditional Mexican medicine

    Guillermo Laguna-Hernández, Carlos A. Rio-Zamorano, Itzel G. Meneses-Ochoa, Alicia E. Brechú-Franco
    21-06-2017
    https://doi.org/10.4081/ejh.2017.2782
    2510
    PDF: 986
    HTML: 372
  • Inhibition of fibrous adhesion formation in the temporomandibular joint of tenascin-C knockout mice

    Y. Shinohara, K. Okamoto, Y. Goh, N. Kiga, I. Tojyo, S. Fujita
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2337
    2960
    PDF: 960
    HTML: 495
  • CCL18 promotes endometriosis by increasing endometrial cell migration and neuroangiogenesis

    Yangying Peng, Shaojie Ding, Ping Xu, Xueyan Zhang, Jianzhang Wang, Tiantian Li, Liyun Liao, Xinmei Zhang
    06-08-2024
    https://doi.org/10.4081/ejh.2024.4052
    1063
    PDF: 735
    HTML: 47
  • Routinely frozen biopsies of human skeletal muscle are suitable for morphological and immunocytochemical analyses at transmission electron microscopy

    M. Giagnacovo, R. Cardani, G. Meola, C. Pellicciari, M. Malatesta
    e31
    08-07-2010
    https://doi.org/10.4081/ejh.2010.e31
    1608
    PDF: 796
    HTML: 9368
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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