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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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3.7
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1.9
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3.7
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  • Histochemistry as a versatile research toolkit in biological research, not only an applied discipline in pathology

    Carlo Pellicciari
    21-12-2018
    https://doi.org/10.4081/ejh.2018.3006
    2254
    PDF: 847
    HTML: 33
  • Infection with CagA-positive Helicobacter pylori strain containing three EPIYA C phosphorylation sites is associated with more severe gastric lesions in experimentally infected Mongolian gerbils (Meriones unguiculatus)

    M. Ferreira Júnior, S.A. Batista, P.V.T. Vidigal, A.A.C. Cordeiro, F.M.S. Oliveira, L.O. Prata, A.E.T. Diniz, C.M. Barral, R.C. Barbuto, A.D. Gomes, I.D. Araújo, D.M.M. Queiroz, M.V. Caliari
    27-04-2015
    https://doi.org/10.4081/ejh.2015.2489
    2278
    PDF: 862
    Supplementary: 343
    HTML: 574
  • A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer

    Daniëlle Krijgsman, Ronald L.P. van Vlierberghe, Vaios Evangelou, Alexander L. Vahrmeijer, Cornelis J.H. van de Velde, Cornelis F.M. Sier, Peter J.K. Kuppen
    20-05-2019
    https://doi.org/10.4081/ejh.2019.3028
    1713
    PDF: 853
    Supplementary: 236
    HTML: 23
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1863
    PDF: 300
    HTML: 37
  • Quantification of morphology of canine circumanal gland tumors: a fractal based study

    I.C. Šoštarić-Zuckermann, K. Severin, M. Huzak, M. Hohšteter, A. Gudan Kurilj, B. Artuković, A. Džaja, Ž. Grabarević
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2609
    1980
    PDF: 784
    HTML: 386
  • High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

    Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari
    16-12-2024
    https://doi.org/10.4081/ejh.2024.4145
    1525
    PDF: 636
    HTML: 12
  • Elevated caspase 3 expression correlates with severe inflammation in Crohn’s disease

    Nafie Sejdiu, Michael Naumann, Michael Vieth
    03-06-2026
    https://doi.org/10.4081/ejh.2026.4570
    386
    PDF: 239
    HTML: 15
  • Pleural mesothelioma from fluoro-edenite exposure: PACAP and PAC1 receptor. A preliminary report

    Claudia Lombardo, Grazia Maugeri, Agata Grazia D'Amico, Giuseppe Broggi, Rosario Caltabiano, Veronica Filetti, Serena Matera, Velia D'Agata, Carla Loreto
    02-05-2024
    https://doi.org/10.4081/ejh.2024.3994
    1986
    PDF: 676
    HTML: 39
  • Successful triple immunoenzymatic method employing primary antibodies from same species and same immunoglobulin subclass

    T. A. Osman, G. Øijordsbakken, D. E. Costea, A. C. Johannessen
    e22
    16-09-2013
    https://doi.org/10.4081/ejh.2013.e22
    3303
    PDF: 950
    HTML: 2124
  • Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study

    A. Santoro, G. Pannone, M.E. Errico, D. Bifano, G. Lastilla, P. Bufo, C. Loreto, V. Donofrio
    e25
    02-07-2012
    https://doi.org/10.4081/ejh.2012.e25
    1627
    PDF: 709
    HTML: 5500
  • Two histological methods for recognition and study of cortical microinfarcts in thick sections

    Heiko Braak, Simone Feldengut, Jan Kassubek, Deniz Yilmazer-Hanke, Kelly Del Tredici
    20-12-2018
    https://doi.org/10.4081/ejh.2018.2989
    2313
    PDF: 947
    HTML: 36
  • Defense and protection mechanisms in lung exposed to asbestiform fiber: the role of macrophage migration inhibitory factor and heme oxygenase-1

    Carla Loreto, Rosario Caltabiano, Adriana Carol Eleonora Graziano, Sergio Castorina, Claudia Lombardo, Vera Filetti, Ermanno Vitale, Giuseppe Rapisarda, Venera Cardile, Caterina Ledda, Venerando Rapisarda
    16-04-2020
    https://doi.org/10.4081/ejh.2020.3073
    1486
    PDF: 877
    HTML: 26
  • MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices

    Elena Casiraghi, Mara Cossa, Veronica Huber, Licia Rivoltini, Matteo Tozzi, Antonello Villa, Barbara Vergani
    02-11-2017
    https://doi.org/10.4081/ejh.2017.2838
    2574
    PDF: 1257
    MIAQuant user Manual: 293
    MIAQuant source code: 375
    HTML: 82
  • Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study

    M. Di Rosa, M.A. Szychlinska, D. Tibullo, L. Malaguarnera, G. Musumeci
    16-09-2014
    https://doi.org/10.4081/ejh.2014.2423
    3128
    PDF: 1268
    HTML: 1616
  • Distribution of alpha-synuclein in normal human jejunum and its relations with the chemosensory and neuroendocrine system

    Arianna Casini, Romina Mancinelli, Caterina Loredana Mammola, Luigi Pannarale, Piero Chirletti, Paolo Onori, Rosa Vaccaro
    02-11-2021
    https://doi.org/10.4081/ejh.2021.3310
    3035
    PDF: 1274
    HTML: 87
  • High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

    Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos
    17-02-2022
    https://doi.org/10.4081/ejh.2022.3360
    2755
    PDF: 1091
    HTML: 47
  • Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor

    Antonio Franchitto, Diletta Overi, Romina Mancinelli, Anna Paola Mitterhofer, Paolo Muiesan, Francesca Tinti, Ilaria Umbro, Stefan G. Hubscher, Paolo Onori, Eugenio Gaudio, Guido Carpino
    10-05-2019
    https://doi.org/10.4081/ejh.2019.3022
    2583
    PDF: 838
    Supplementary: 307
    HTML: 20
  • 3-hydroxi-anthranilic acid is early expressed in stroke

    A. Mangas, J. Yajeya, N. González, I. Ruiz, M. Geffard, R. Coveñas
    02-12-2016
    https://doi.org/10.4081/ejh.2016.2709
    2428
    PDF: 763
    HTML: 317
  • Mena, a new available marker in tumors of salivary glands?

    S. Gurzu, M. Krause, I. Ember, L. Azamfirei, G. Gobel, K. Feher, I. Jung
    e8
    07-02-2012
    https://doi.org/10.4081/ejh.2012.e8
    1470
    PDF: 741
    HTML: 4184
  • NO-tryptophan: a new small molecule located in the rat brain

    A. Mangas, J. Yajeya, N. González, S. Duleu, M. Geffard, R. Coveñas
    22-09-2016
    https://doi.org/10.4081/ejh.2016.2692
    2148
    PDF: 628
    HTML: 250
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    368
    PDF: 484
    HTML: 19
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2788
    PDF: 1090
    HTML: 163
  • Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

    M. Costanzo, B. Cisterna, A. Vella, T. Cestari, V. Covi, G. Tabaracci, M. Malatesta
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2515
    3201
    PDF: 1069
    HTML: 415
  • FROM CLOUD TO BEDSIDE C. Tacchetti1,2 | 1Medical School & S.RACE (San-Raffaele Artificial Intelligence Center);Vita-Salute University San Raffaele, Milan, Italy; 2Experimental Imaging Center, IRCCS Hospital San Raffaele, Milan, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4294
    241
  • Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1

    S. Iachettini, R. Valaperta, A. Marchesi, A. Perfetti, G. Cuomo, B. Fossati, L. Vaienti, E. Costa, G. Meola, R. Cardani
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2562
    2113
    PDF: 997
    HTML: 400
  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    753
    PDF: 435
    Raw data: 62
    HTML: 23
  • Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour

    W. Meyer, M. Liumsiricharoen, A. Suprasert, L.G. Fleischer, M. Hewicker-Trautwein
    e27
    16-09-2013
    https://doi.org/10.4081/ejh.2013.e27
    3594
    PDF: 1289
    HTML: 527
  • Effect of high-fat mixed lipid diet and swimming on fibre types in skeletal muscles of rats with colon tumours

    Vika Smerdu, Martina Perše
    25-07-2018
    https://doi.org/10.4081/ejh.2018.2945
    2032
    PDF: 829
    HTML: 54
  • Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

    V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas
    e5
    08-02-2011
    https://doi.org/10.4081/ejh.2011.e5
    1550
    PDF: 842
    HTML: 3580
  • The penetration of methanol into bovine cardiac and hepatic tissues is faster than ethanol and formalin

    Michelle Steicke, Guang Yang, Tam Nguyen Dinh, Matthew Dunster-Jones, Owen Sargisson, Farah Ahmady, Jonathan Golledge, Yutang Wang
    07-02-2018
    https://doi.org/10.4081/ejh.2018.2880
    2135
    PDF: 893
    Supplementary: 223
    HTML: 62
  • Bile duct ligature in young rats: A revisited animal model for biliary atresia

    Matias Garrido, Camila Escobar, Constanza Zamora, Carolina Rejas, Juan Varas, Mario Párraga, Sebastián San Martin, Sandra Montedonico
    13-09-2017
    https://doi.org/10.4081/ejh.2017.2803
    2316
    PDF: 1044
    HTML: 159
  • Developmental characteristics of cutaneous telocytes in late embryos of the silky fowl

    Hao Li, Junliang Chen, Wenjun You, Yizhen Xu, Yaqiong Ye, Haiquan Zhao, Junxing Li, Hui Zhang
    15-10-2024
    https://doi.org/10.4081/ejh.2024.4089
    1839
    PDF: 463
    HTML: 21
  • DNA damage in acute myeloid leukemia patients of Northern Mexico

    Martha I. Dávila-Rodríguez, Elva I. Cortés-Gutiérrez, Roberto Hernández-Valdés, Karla Guzmán-Cortés, Rosa E. De León-Cantú, Ricardo M. Cerda-Flores, Enrique Báez-De la Fuente
    11-12-2017
    https://doi.org/10.4081/ejh.2017.2851
    1793
    PDF: 610
    HTML: 146
  • Ultrastructure of telocytes, a new type of interstitial cells in the myocardium of the Chinese giant salamander (Andrias davidianus)

    Tingting Ge, Yaqiong Ye, Hui Zhang
    23-05-2019
    https://doi.org/10.4081/ejh.2019.3021
    1867
    PDF: 905
    HTML: 17
  • Porcine intestinal mast cells. Evaluation of different fixatives for histochemical staining techniques considering tissue shrinkage

    J. Rieger, S. Twardziok, H. Huenigen, R. M. Hirschberg, J. Plendl
    e21
    30-07-2013
    https://doi.org/10.4081/ejh.2013.e21
    4386
    PDF: 1239
    HTML: 1305
  • Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

    Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié
    21-08-2025
    https://doi.org/10.4081/ejh.2025.4174
    730
    PDF: 529
    HTML: 32
  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2374
    PDF: 1313
    Supplementary: 125
    HTML: 241
  • Evolutionary intraembryonic origin of vertebrate hematopoietic stem cells in the elasmobranch spleen

    Rosa Manca, Chester A. Glomski, Alessandra Pica
    20-12-2018
    https://doi.org/10.4081/ejh.2018.2987
    1730
    PDF: 743
    HTML: 41
  • Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

    D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev
    05-08-2015
    https://doi.org/10.4081/ejh.2015.2530
    2881
    PDF: 976
    HTML: 1393
  • Mast cells in meningiomas

    Antonio D'Amati, Roberto Tamma, Tiziana Annese, Anna Rizzi, Domenico Ribatti
    18-04-2024
    https://doi.org/10.4081/ejh.2024.3973
    1595
    PDF: 517
    HTML: 29
  • Localization of peripheral autonomic neurons innervating the boar urinary bladder trigone and neurochemical features of the sympathetic component

    L. Ragionieri, M. Botti, F. Gazza, C. Sorteni, R. Chiocchetti, P. Clavenzani, L. Bo, R. Panu
    e16
    06-05-2013
    https://doi.org/10.4081/ejh.2013.e16
    2570
    PDF: 1238
    HTML: 1043
  • Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma

    Romina Mancinelli, Antimo Cutone, Luigi Rosa, Maria Stefania Lepanto, Paolo Onori, Luigi Pannarale, Antonio Franchitto, Eugenio Gaudio, Piera Valenti
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3156
    1830
    PDF: 819
    HTML: 27
  • Dark-field microscopy enhance visibility of CD31 endothelial staining

    Eva Jennische, Stefan Lange, Ragnar Hultborn
    01-07-2020
    https://doi.org/10.4081/ejh.2020.3133
    1655
    PDF: 813
    HTML: 18
  • Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

    Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan
    13-05-2024
    https://doi.org/10.4081/ejh.2024.3917
    2183
    PDF: 931
    HTML: 60
  • Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study

    Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi
    31-07-2018
    https://doi.org/10.4081/ejh.2018.2956
    2077
    PDF: 1041
    Supplementary: 235
    HTML: 53
  • Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma

    Chiara Rita Inguscio, Barbara Cisterna, Maria Assunta Lacavalla, Franco Donati, Osvaldo Angelini, Gabriele Tabaracci, Manuela Malatesta
    10-10-2023
    https://doi.org/10.4081/ejh.2023.3879
    4852
    PDF: 848
    HTML: 33
  • The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model

    Roman M. Kassa, Roberta Bonafede, Federico Boschi, Manuela Malatesta, Raffaella Mariotti
    17-05-2018
    https://doi.org/10.4081/ejh.2018.2904
    2223
    PDF: 781
    HTML: 34
  • Immunohistochemical study of doublecortin and nucleostemin in canine brain

    E. De Nevi, P. Marco-Salazar, D. Fondevila, E. Blasco, L. Pérez, M. Pumarola
    e9
    20-03-2013
    https://doi.org/10.4081/ejh.2013.e9
    2687
    PDF: 789
    HTML: 286
  • Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells in vitro

    Xilin Ge, Caoxin Huang, Wenting Chen, Chen Yang, Wenfang Huang, Jia Li, Shuyu Yang
    25-11-2024
    https://doi.org/10.4081/ejh.2024.4140
    2235
    PDF: 749
    HTML: 34
  • Expression of hyaluronan synthase 3 in deformed human temporomandibular joint discs: in vivo and in vitro studies

    T. Matsumoto, M. Inayama, I. Tojyo, N. Kiga, S. Fujita
    e50
    15-12-2010
    https://doi.org/10.4081/ejh.2010.e50
    1747
    PDF: 751
    HTML: 1421
  • Postsynaptic cleft density changes with combined exercise protocols in an experimental model of muscular hypertrophy

    Jurandyr Pimentel Neto, Lara Caetano Rocha, Carolina dos Santos Jacob, Gabriela Klein Barbosa, Adriano Polican Ciena
    04-08-2021
    https://doi.org/10.4081/ejh.2021.3274
    1424
    PDF: 626
    HTML: 25
  • Histochemistry and immunolocalisation of glucokinin in antidiabetic plants used in traditional Mexican medicine

    Guillermo Laguna-Hernández, Carlos A. Rio-Zamorano, Itzel G. Meneses-Ochoa, Alicia E. Brechú-Franco
    21-06-2017
    https://doi.org/10.4081/ejh.2017.2782
    2577
    PDF: 1033
    HTML: 374
  • Inhibition of fibrous adhesion formation in the temporomandibular joint of tenascin-C knockout mice

    Y. Shinohara, K. Okamoto, Y. Goh, N. Kiga, I. Tojyo, S. Fujita
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2337
    3049
    PDF: 1006
    HTML: 507
  • CCL18 promotes endometriosis by increasing endometrial cell migration and neuroangiogenesis

    Yangying Peng, Shaojie Ding, Ping Xu, Xueyan Zhang, Jianzhang Wang, Tiantian Li, Liyun Liao, Xinmei Zhang
    06-08-2024
    https://doi.org/10.4081/ejh.2024.4052
    1169
    PDF: 790
    HTML: 50
  • Routinely frozen biopsies of human skeletal muscle are suitable for morphological and immunocytochemical analyses at transmission electron microscopy

    M. Giagnacovo, R. Cardani, G. Meola, C. Pellicciari, M. Malatesta
    e31
    08-07-2010
    https://doi.org/10.4081/ejh.2010.e31
    1652
    PDF: 825
    HTML: 9427
  • Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

    Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4218
    1783
    PDF: 691
    HTML: 38
  • Muscleblind-like1 undergoes ectopic relocation in the nuclei of skeletal muscles in myotonic dystrophy and sarcopenia

    M. Malatesta, M. Giagnacovo, M. Costanzo, B. Cisterna, R. Cardani, G. Meola
    e15
    22-04-2013
    https://doi.org/10.4081/ejh.2013.e15
    3021
    PDF: 4378
    HTML: 474
  • Antigen retrieval pre-treatment causes a different expression pattern of Cav3.2 in rat and mouse spinal dorsal horn

    Xiao E Cheng, Long Xian Ma, Xiao Jin Feng, Meng Ye Zhu, Da Ying Zhang, Lin Lin Xu, Tao Liu
    23-01-2019
    https://doi.org/10.4081/ejh.2019.2988
    2162
    PDF: 949
    Supplementary: 264
    HTML: 47
  • Calcium-induced alteration of mitochondrial morphology and mitochondrial-endoplasmic reticulum contacts in rat brown adipocytes

    I. Golic, K. Velickovic, M. Markelic, A. Stancic, A. Jankovic, M. Vucetic, V. Otasevic, B. Buzadzic, B. Korac, A. Korac
    09-09-2014
    https://doi.org/10.4081/ejh.2014.2377
    3532
    PDF: 1250
    HTML: 1551
  • Histochemical localization of sialic acids and antimicrobial substances in eccrine glands of porcine snout skin

    K. Fukui, T. Yasui, H. Gomi, H. Sugiya, O. Fujimori, W. Meyer, A. Tsukise
    e6
    09-02-2012
    https://doi.org/10.4081/ejh.2012.e6
    1945
    PDF: 926
    HTML: 6847
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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