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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesions

    L. Pilloni, P. Bianco, E. DiFelice, S. Cabras, M.E. Castellanos, L. Atzori, C. Ferreli, P. Mulas, S. Nemolato, G. Faa
    e20
    07-06-2011
    https://doi.org/10.4081/ejh.2011.e20
    1253
    PDF: 675
    HTML: 9917
  • Varying effects of EGF, HGF and TGFβ on formation of invadopodia and invasiveness of melanoma cell lines of different origin

    A. Makowiecka, A. Simiczyjew, D. Nowak, A.J. Mazur
    09-12-2016
    https://doi.org/10.4081/ejh.2016.2728
    2210
    PDF: 901
    Supplementary: 274
    HTML: 414
  • Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi
    23-06-2022
    https://doi.org/10.4081/ejh.2022.3377
    1622
    PDF: 834
    HTML: 24
  • MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices

    Elena Casiraghi, Mara Cossa, Veronica Huber, Licia Rivoltini, Matteo Tozzi, Antonello Villa, Barbara Vergani
    02-11-2017
    https://doi.org/10.4081/ejh.2017.2838
    2369
    PDF: 1157
    MIAQuant user Manual: 252
    MIAQuant source code: 310
    HTML: 71
  • Bleaching melanin in formalin-fixed and paraffin-embedded melanoma specimens using visible light: a pilot study

    Claudio Pigoli, Lucia Rita Gibelli, Mario Caniatti, Luca Moretti, Giuseppe Sironi, Chiara Giudice
    31-10-2019
    https://doi.org/10.4081/ejh.2019.3071
    1586
    PDF: 932
    HTML: 10
  • Characterization of PD-1/PD-L1 immune checkpoint expression in soft tissue sarcomas

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Masao Akagi
    02-07-2021
    https://doi.org/10.4081/ejh.2021.3203
    2997
    PDF: 894
    HTML: 29
  • Clinicopathological assessment of PD-1/PD-L1 immune checkpoint expression in desmoid tumors

    Kazuhiko Hashimoto, Shunji Nishimura, Yu Shinyashiki, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi
    26-04-2023
    https://doi.org/10.4081/ejh.2023.3688
    819
    PDF: 504
    HTML: 20
  • Prognostic prediction of the immunohistochemical expression of p16 and p53 in cutaneous melanoma: a comparison of two populations from different geographical regions

    P Sirigu, F Piras, L Minerba, D Murtas, C Maxia, R Colombari, A Corbu, MT Perra, J Ugalde
    191-198
    30-06-2009
    https://doi.org/10.4081/992
    551
    PDF: 638
  • Expression of SPANX proteins in normal prostatic tissue and in prostate cancer

    M. Salemi, A. E. Calogero, G. Zaccarello, R. Castiglione, A. Cosentino, C. Campagna, E. Vicari, G. Rappazzo
    e41
    09-09-2010
    https://doi.org/10.4081/ejh.2010.e41
    1513
    PDF: 504
    HTML: 1327
  • MAGE-A3/4 and NY-ESO-1 antigens expression in metastatic esophageal squamous cell carcinoma

    T. Bujas, Z. Marusic, M. Peric Balja, A. Mijic, B. Kruslin, D. Tomas
    e7
    21-03-2011
    https://doi.org/10.4081/ejh.2011.e7
    1784
    PDF: 783
    HTML: 979
  • EXPLORING THE CYTOTOXIC AND APOPTOTIC ACTIVITIES OF PRUNUS SPINOSA ECOTYPE EXTRACT TRIGNO ON 3D AND 2D MODELS OF HUMAN CANCER CELLS A. Di Netta1, A. Di Pauli2, R. Vona3, C. Cittadini3, S. Meschini1, M. Condello1 | 1 National Center for Drug Research and Evaluation, National Institute of Health, Rome, Italy; 2 Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, «Sapienza» University of Rome, Rome, Italy: 3 National Center for Gender-Specific Medicine, National Institute of Health, Rome, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4319
    254
  • NOP14 regulates the growth, migration, and invasion of colorectal cancer cells by modulating the NRIP1/GSK-3β/β-catenin signaling pathway

    Xuanjin Zhu, Weilu Jia, Yong Yan, Yong Huang, Bailin Wang
    02-07-2021
    https://doi.org/10.4081/ejh.2021.3246
    2680
    PDF: 725
    HTML: 36
  • Lectins as versatile tools to explore cellular glycosylation

    Susan Brooks
    29-01-2024
    https://doi.org/10.4081/ejh.2024.3959
    2439
    PDF: 1151
    HTML: 45
  • PARP-1 protein expression in glioblastoma multiforme

    A. Galia, A.E. Calogero, R. Condorelli, F. Fraggetta, A. La Corte, F. Ridolfo, P. Bosco, R. Castiglione, M. Salemi
    e9
    27-02-2012
    https://doi.org/10.4081/ejh.2012.e9
    3107
    PDF: 1231
    HTML: 1794
  • ROLE OF SCHWANN CELLS-CANCER CELLS CROSSTALK IN TUMOUR PROGRESSION C. Giampietri1, E. Pizzichini1, F. Somma1, S. Petrungaro1, A. Facchiano2, A. Filippini1, C. Fabrizi1, E. Gaudio1 | 1Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Rome, Italy; 2Istituto Dermopatico dell’Immacolata, IDI-IRCCS, Rome, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4276
    168
  • KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion

    A. Porzionato, G. Fenu, M. Rucinski, V. Macchi, A. Montella, L. K. Malendowicz, R. De Caro
    e14
    04-05-2011
    https://doi.org/10.4081/ejh.2011.e14
    1221
    PDF: 517
    HTML: 1052
  • KiSS1 inhibits growth and invasion of osteosarcoma cells through inhibition of the MAPK pathway

    Y. Zhang, Y.J. Tang, Z.H. Li, F. Pan, K. Huang, G.H. Xu
    e30
    29-10-2013
    https://doi.org/10.4081/ejh.2013.e30
    2766
    PDF: 616
    HTML: 313
  • Neurokinin-1 receptor is highly expressed in cervical cancer and its antagonist induces cervical cancer cell apoptosis

    Liyun Guan, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang
    11-01-2023
    https://doi.org/10.4081/ejh.2023.3570
    1371
    PDF: 662
    HTML: 35
  • Characterization of the role of RILP in cell migration

    Azzurra Margiotta, Cinzia Progida, Oddmund Bakke, Cecilia Bucci
    31-05-2017
    https://doi.org/10.4081/ejh.2017.2783
    2421
    PDF: 941
    Supplementary: 238
    Movie 1: 325
    Movie 2: 369
    HTML: 100
  • Poly (ADP-ribose) polymerase 1 protein expression in normal and neoplastic prostatic tissue

    M. Salemi, A. Galia, F. Fraggetta, C. La Corte, P. Pepe, S. La Vignera, G. Improta, P. Bosco, A.E. Calogero
    e13
    15-04-2013
    https://doi.org/10.4081/ejh.2013.e13
    2823
    PDF: 3232
    HTML: 228
  • High temperature requirement A1 and fibronectin: two possible players in placental tissue remodelling

    G. Tossetta, C. Avellini, C. Licini, S.R. Giannubilo, M. Castellucci, D. Marzioni
    21-11-2016
    https://doi.org/10.4081/ejh.2016.2724
    1618
    PDF: 636
    HTML: 157
  • IMP-3 expression in keratoacanthomas and squamous cell carcinomas of the skin: an immunohistochemical study

    S. Soddu, E. Di Felice, S. Cabras, M.E. Castellanos, L. Atzori, G. Faa, L. Pilloni
    e6
    14-02-2013
    https://doi.org/10.4081/ejh.2013.e6
    1433
    PDF: 688
    HTML: 466
  • Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

    Jiapei Lv, Wang Yanting, Shan Wei
    08-11-2023
    https://doi.org/10.4081/ejh.2023.3867
    1884
    PDF: 916
    HTML: 41
  • Thymosin beta 4 and thymosin beta 10 expression in hepatocellular carcinoma

    W. Theunissen, D. Fanni, S. Nemolato, E. Di Felice, T. Cabras, C. Gerosa, P. Van Eyken, I. Messana, M. Castagnola, G. Faa
    11-03-2014
    https://doi.org/10.4081/ejh.2014.2242
    3145
    PDF: 999
    HTML: 486
  • High temperature requirement A1, transforming growth factor beta1, phosphoSmad2 and Ki67 in eutopic and ectopic endometrium of women with endometriosis

    G. Goteri, E. Altobelli, G. Tossetta, A. Zizzi, C. Avellini, C. Licini, T. Lorenzi, M. Castellucci, A. Ciavattini, D. Marzioni
    09-12-2015
    https://doi.org/10.4081/ejh.2015.2570
    2576
    PDF: 789
    HTML: 409
  • Protective effect of different antioxidant agents in UVB-irradiated keratinocytes

    Sara Salucci, Sabrina Burattini, Francesca Buontempo, Alberto Maria Martelli, Elisabetta Falcieri, Michela Battistelli
    18-09-2017
    https://doi.org/10.4081/ejh.2017.2784
    2358
    PDF: 975
    HTML: 178
  • Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

    J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei
    17-03-2014
    https://doi.org/10.4081/ejh.2014.2263
    3400
    PDF: 970
    HTML: 583
  • Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

    Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou
    02-12-2021
    https://doi.org/10.4081/ejh.2021.3331
    2457
    PDF: 1411
    HTML: 36
  • Sox9 expression in canine epithelial skin tumors

    E. Fantinato, L. Milani, G. Sironi
    09-07-2015
    https://doi.org/10.4081/ejh.2015.2514
    3079
    PDF: 833
    HTML: 406
  • Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma

    Zhiyang Wang, Jing Li, Ziwei Liu, Ling Yue
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3622
    1104
    PDF: 688
    HTML: 33
  • Fibroblast activating protein-α expression in squamous cell carcinoma of the esophagus in primary and irradiated tumors: the use of archival FFPE material for molecular techniques

    Renata Tabola, Magdalena Zaremba-Czogalla, Dagmara Baczynska, Roberto Cirocchi, Kamila Stach, Krzysztof Grabowski, Katarzyna Augoff
    20-06-2017
    https://doi.org/10.4081/ejh.2017.2793
    1737
    PDF: 725
    HTML: 95
  • FLOW CYTOMETRY IN THE DEVELOPMENT AND CHARACTERIZATION OF PRECLINICAL TUMOR MODELS BASED ON THE ANALYSIS OF EXTRACELLULAR VESICLES AS CANDIDATE LIQUID BIOMARKERS I. D’Agnano | Institute of Biomedical Technologies, CNR, Segrate, Milan, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4303
    153
  • Immunolocalization of lactoferrin in surgically resected pigmented skin lesions

    G Tuccari, G Giuffrè, R Scarfì, A Simone, P Todaro, G Barresi
    33-38
    29-06-2009
    https://doi.org/10.4081/924
    884
    PDF: 770
  • Lipofuscin, lipofuscin-like pigments and autofluorescence

    G. Di Guardo
    06-02-2015
    https://doi.org/10.4081/ejh.2015.2485
    4140
    PDF: 1811
    HTML: 508
  • Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

    A.C. Croce, G. Bottiroli
    12-12-2014
    https://doi.org/10.4081/ejh.2014.2461
    13512
    PDF: 5745
    HTML: 7958
  • alpha2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade

    Michael W.L. Quirino, Amanda P.B. Albuquerque, Maria F.D. de Souza, Antônio F. da Silva Filho, Mário R. Martins, Maira G. da Rocha Pitta, Michelly C. Pereira, Moacyr J.B. de Melo Rêgo
    29-09-2022
    https://doi.org/10.4081/ejh.2022.3330
    1292
    PDF: 672
    Supplementary: 120
    HTML: 28
  • Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

    Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin
    23-10-2024
    https://doi.org/10.4081/ejh.2024.4098
    2081
    PDF: 413
    HTML: 20
  • Expression patterns of α2,3-Sialyltransferase I and α2,6-Sialyltransferase I in human cutaneous epithelial lesions

    S.A. Ferreira, J.L.A. Vasconcelos, R.C.W.C. Silva, C.L.B. Cavalcanti, C.L. Bezerra, M.J.B.M. Rêgo, E.I.C. Beltrão
    e7
    14-02-2013
    https://doi.org/10.4081/ejh.2013.e7
    1471
    PDF: 708
    HTML: 230
  • Analysis of extracellular superoxide dismutase and Akt in ascending aortic aneurysm with tricuspid or bicuspid aortic valve

    A. Arcucci, M.R. Ruocco, F. Albano, G. Granato, V. Romano, G. Corso, C. Bancone, E. De Vendittis, A. Della Corte, S. Montagnani
    18-07-2014
    https://doi.org/10.4081/ejh.2014.2383
    2155
    PDF: 2159
    HTML: 348
  • Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner

    Jana Oswald, Maximilian Büttner, Simon Jasinski-Bergner, Roland Jacobs, Philip Rosenstock, Heike Kielstein
    26-01-2018
    https://doi.org/10.4081/ejh.2018.2848
    3244
    PDF: 1159
    HTML: 105
  • Differential expression patterns of N-acetylglucosaminyl transferases and polylactosamines in uterine lesions

    A.T.R. Clark, V.M.L. Guimaraes da Costa, L. Bandeira Costa, C.L. Bezerra Cavalcanti, M.J.B. de Melo Rego, E.I.C. Beltrao
    26-05-2014
    https://doi.org/10.4081/ejh.2014.2334
    2381
    PDF: 1712
    HTML: 399
  • A spectrofluorometric analysis to evaluate transcutaneous biodistribution of fluorescent nanoparticulate gel formulations

    Enrica Cappellozza, Federico Boschi, Maddalena Sguizzato, Elisabetta Esposito, Rita Cortesi, Manuela Malatesta, Laura Calderan
    07-02-2022
    https://doi.org/10.4081/ejh.2022.3321
    1577
    PDF: 633
    HTML: 22
  • Reinke's Edema: investigations on the role of MIB-1 and hepatocyte growth factor

    M. Artico, E. Bronzetti, B. Ionta, M. Bruno, A. Greco, G. Ruoppolo, A. De Virgilio, L. Longo, M. De Vincentiis
    e30
    08-07-2010
    https://doi.org/10.4081/ejh.2010.e30
    1053
    PDF: 446
    HTML: 5983
  • Ultrastructural analysis of different human mesenchymal stem cells after in vitro expansion: a technical review

    M. Miko, L. Danisovic, A. Majidi, I. Varga
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2528
    2506
    PDF: 829
    HTML: 833
  • Radioprotective potential of histamine on rat small intestine and uterus

    E. Carabajal, N. Massari, M. Croci, D. J. Martinel Lamas, J. P. Prestifilippo, R. M. Bergoc, E. S. Rivera, V. A. Medina
    e48
    18-12-2012
    https://doi.org/10.4081/ejh.2012.e48
    1258
    PDF: 695
    HTML: 908
  • MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9

    Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3275
    1857
    PDF: 767
    Supplementary: 135
    HTML: 33
  • Subcellular distribution and expression of cofilin and ezrin in human colon adenocarcinoma cell lines with different metastatic potential

    D. Nowak, A. J. Mazur, A. Popow-Woźniak, A. Radwańska, H. G. Mannherz, M. Malicka-Błaszkiewicz
    e14
    13-04-2010
    https://doi.org/10.4081/ejh.2010.e14
    1665
    PDF: 617
    HTML: 2671
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European Journal of Histochemistry

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