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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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1.9
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3.7
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  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    1245
    PDF: 590
    HTML: 21
  • Expression profile of the zinc transporter ZnT3 in taste cells of rat circumvallate papillae and its role in zinc release, a potential mechanism for taste stimulation

    Kentaro Nishida, Saho Bansho, Akiko Ikukawa, Teruyo Kubota, Akihiro Ohishi, Kazuki Nagasawa
    10-11-2022
    https://doi.org/10.4081/ejh.2022.3534
    1308
    PDF: 726
    Supplementary: 175
    HTML: 36
  • MicroRNA-29b-3p promotes 5-fluorouracil resistance via suppressing TRAF5-mediated necroptosis in human colorectal cancer

    Shuimei Wu, Yun Zhou, Ping Liu, Hui Zhang, Wanliang Wang, Yuan Fang, Xiang Shen
    22-06-2021
    https://doi.org/10.4081/ejh.2021.3247
    2074
    PDF: 1007
    Supplementary: 203
    HTML: 21
  • Fibroblast activating protein-α expression in squamous cell carcinoma of the esophagus in primary and irradiated tumors: the use of archival FFPE material for molecular techniques

    Renata Tabola, Magdalena Zaremba-Czogalla, Dagmara Baczynska, Roberto Cirocchi, Kamila Stach, Krzysztof Grabowski, Katarzyna Augoff
    20-06-2017
    https://doi.org/10.4081/ejh.2017.2793
    1825
    PDF: 764
    HTML: 100
  • An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage

    K. Fujikawa, T. Yokohama-Tamaki, T. Morita, O. Baba, C. Qin, S. Shibata
    25-09-2015
    https://doi.org/10.4081/ejh.2015.2553
    1591
    PDF: 852
    HTML: 552
  • Knockdown of RAGE inhibits growth and invasion of gastric cancer cells

    X.C. Xu, X. Abuduhadeer, W.B. Zhang, T. Li, H. Gao, Y.H. Wang
    e36
    18-11-2013
    https://doi.org/10.4081/ejh.2013.e36
    4313
    PDF: 845
    HTML: 268
  • MPTP-induced increase in c-Fos- and c-Jun-like immunoreactivity in the monkey cerebellum

    D Necchi, C Soldani, F Ronchetti, G Bernocchi, E Scherini
    385-392
    29-06-2009
    https://doi.org/10.4081/912
    536
    PDF: 2372
  • Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability

    Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3352
    1762
    PDF: 783
    HTML: 34
  • The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis

    Andrea Ferrigno, Clarissa Berardo, Laura Giuseppina Di Pasqua, Marta Cagna, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti
    10-11-2020
    https://doi.org/10.4081/ejh.2020.3175
    1912
    PDF: 972
    Supplementary: 195
    HTML: 31
  • Epidermal growth factor-like domain multiple 7 (EGFL7): Expression and possible effect on biliary epithelium growth in cholangiocarcinoma

    Caterina L. Mammola, Antonella Vetuschi, Luigi Pannarale, Roberta Sferra, Romina Mancinelli
    30-11-2018
    https://doi.org/10.4081/ejh.2018.2971
    1443
    PDF: 766
    Supplementary: 186
    HTML: 27
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2724
    PDF: 846
    HTML: 347
  • Investigating conversion of endplate chondrocytes induced by intermittent cyclic mechanical unconfined compression in three-dimensional cultures

    H.G. Xu, W. Zhang, Q. Zheng, Y.F. Yu, L.F. Deng, H. Wang, P. Liu, M. Zhang
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2415
    1750
    PDF: 798
    HTML: 373
  • Effects of pre- and postnatal exposure to flutamide on connexin 43 expression in testes and ovaries of prepubertal pigs

    I. Kopera, M. Durlej, A. Hejmej, K. Knapczyk-Stwora, M. Duda, M. Slomczynska, M. Koziorowski, B. Bilinska
    e15
    14-04-2010
    https://doi.org/10.4081/ejh.2010.e15
    1628
    PDF: 936
    HTML: 5531
  • 74 | IMPACT OF IVERMECTIN ON THE GONADS OF THE MARINE MUSSEL MYTILUS GALLOPROVINCIALIS AND REPERCUSSION ON THE EMBRYO DEVELOPMENT M. Terranova1|2|3, G. La Pusata2, N. Caruso1|2, M. Galati2, A. Fazio2, T. Cappello2, M. Maisano2 | 1Dept. of Earth and Marine Sciences, University of Palermo, Italy; 2Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 3National Biodiversity Future Center (NBFC), Palermo, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4692
    21
    PDF: 4
  • P59 | IMMUNOHISTOCHEMISTRY ANALYSIS TO DETECT A MOLECULAR SIGNATURE IN INTERVERTEBRAL DISC DEGENERATION L. Penolazzi1, R. Nadalini1, C. Sief1, E. Lambertini2, C. Angelini3, R. Piva1 | 1Department of Neurosciences and rehabilitation, University of Ferrara, Italy; 2Laboratorio Centralizzato di ricerca preclinica, University of Ferrara, Italy; 3Department of Translational Medicine, University of Ferrara, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4384
    271
  • Seasonal expressions of VEGF and its receptors VEGFR1 and VEGFR2 in the prostate of the wild ground squirrels (Spermophilus dauricus)

    Yuchen Yao, Wenqian Xie, Di Chen, Yingying Han, Zhengrong Yuan, Haolin Zhang, Qiang Weng
    24-03-2021
    https://doi.org/10.4081/ejh.2021.3219
    1465
    PDF: 570
    HTML: 45
  • Presence of N-acetylneuraminic acid in the lung during postnatal development

    Maria de Fátima Martins, Marco S. Reis, Ana Honório-Ferreira, Carlos Alberto Gonçalves
    06-05-2020
    https://doi.org/10.4081/ejh.2020.3124
    1535
    PDF: 591
    HTML: 28
  • Nuclei of aged myofibres undergo structural and functional changes suggesting impairment in RNA processing

    M Malatesta, F Perdoni, S Muller, C Zancanaro, C Pellicciari
    e12
    17-08-2009
    https://doi.org/10.4081/ejh.2009.e12
    1512
    PDF: 850
  • Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study

    Giada Remoli, Chiara Rita Inguscio, Federico Boschi, Gabriele Tabaracci, Manuela Malatesta, Barbara Cisterna
    26-01-2026
    https://doi.org/10.4081/ejh.2026.4440
    1231
    PDF: 229
    HTML: 13
  • High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

    Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos
    17-02-2022
    https://doi.org/10.4081/ejh.2022.3360
    2551
    PDF: 1003
    HTML: 43
  • Tripartite motif-containing protein 6 facilitates growth and migration of breast cancer through degradation of STUB1

    Chuanchao Wei, Jiayue Wu, Weiyan Liu, Jingfeng Lu, Hongchang Li, Benjun Hai
    10-03-2021
    https://doi.org/10.4081/ejh.2021.3214
    1752
    PDF: 858
    Supplementary: 167
    HTML: 19
  • An ex vivo study on immunohistochemical localization of MMP-7 and MMP-9 in temporomandibular joint discs with internal derangement

    C. Loreto, R. Leonardi, G. Musumeci, G. Pannone, S. Castorina
    e12
    15-04-2013
    https://doi.org/10.4081/ejh.2013.e12
    2866
    PDF: 861
    HTML: 442
  • Cellular programming and reprogramming - Methods and protocols

    CarloAlberto Redi
    16-12-2010
    https://doi.org/10.4081/1763
    883
    PDF: 488
    HTML: 199
  • Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

    Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4034
    1201
    PDF: 624
    HTML: 12
  • Postsynaptic cleft density changes with combined exercise protocols in an experimental model of muscular hypertrophy

    Jurandyr Pimentel Neto, Lara Caetano Rocha, Carolina dos Santos Jacob, Gabriela Klein Barbosa, Adriano Polican Ciena
    04-08-2021
    https://doi.org/10.4081/ejh.2021.3274
    1302
    PDF: 569
    HTML: 23
  • Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity

    Bita Moudi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Seyed-Moayed Alavian, Kamran B. Lankarani, Parisa Farrokh, Jens Randel Nyengaard
    29-01-2018
    https://doi.org/10.4081/ejh.2018.2859
    2248
    PDF: 1081
    HTML: 81
  • Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse

    A. Vetuschi, A. D'Alfonso, R. Sferra, D. Zanelli, S. Pompili, F. Patacchiola, E. Gaudio, G. Carta
    16-02-2016
    https://doi.org/10.4081/ejh.2016.2604
    2323
    PDF: 936
    HTML: 631
  • Expression level of quiescin sulfhydryl oxidase 1 (QSOX1) in neuroblastomas

    D.G.B. Araújo, L. Nakao, P. Gozzo, C.D.A. Souza, V. Balderrama, E.S. Gugelmin, A.P. Kuczynski, M. Olandoski, L. de Noronha
    06-03-2014
    https://doi.org/10.4081/ejh.2014.2228
    3029
    PDF: 1261
    HTML: 364
  • Large-scale chromatin morpho-functional changes during mammalian oocyte growth and differentiation

    A.M. Luciano, V. Lodde, F. Franciosi, I. Tessaro, D. Corbani, S. Modina
    e37
    10-08-2012
    https://doi.org/10.4081/ejh.2012.e37
    1328
    PDF: 879
  • Hydrophobins in ectomycorrhizas: heterologous transcription of the Pisolithus HydPt-1 gene in yeast and Hebeloma cylindrosporum

    D Tagu, R Marmeisse, Y Baillet, S Rivière, B Palin, F Bernardini, A Méreau, G Gay, R Balestrini, P Bonfante, F Martin
    23-30
    30-12-2009
    https://doi.org/10.4081/1651
    754
    PDF: 662
  • SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

    Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang
    18-05-2026
    https://doi.org/10.4081/ejh.2026.4544
    162
    PDF: 126
    Supplementary: 21
    HTML: 6
  • Establishment and biological characteristics of a Jingning chicken embryonic fibroblast bank

    C. Bai, D. Wang, C. Li, D. Jin, C. Li, W. Guan, Y. Ma
    e4
    29-03-2011
    https://doi.org/10.4081/ejh.2011.e4
    1892
    PDF: 733
    HTML: 6761
  • Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells

    D Waltregny, B North, F Van Mellaert, J de Leval, E Verdin, V Castronovo
    273-290
    29-06-2009
    https://doi.org/10.4081/897
    1022
    PDF: 1442
  • Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cells via miR-6739-5p modulation and PI3K/AKT pathway activation: a functional histocytochemical study

    Zefeng Sun, Xinrong Fan, Zhenquan Liu
    02-10-2025
    https://doi.org/10.4081/ejh.2025.4253
    391
    PDF: 351
    HTML: 40
  • Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy

    Fenqiang Qi, Yuxin Deng, Wei Huang, Yanli Cai, Kelin Hong, Shui Xiang
    15-10-2024
    https://doi.org/10.4081/ejh.2024.4104
    2416
    PDF: 593
    HTML: 7
  • Effects of the lncRNA ENST00000623984 on colon cancer and the biological characteristics of colon cancer cells

    Zhi-bao Liu, Jing-hua Zhang, Jing-hua Gao, Jian Shi
    12-07-2021
    https://doi.org/10.4081/ejh.2021.3215
    2199
    PDF: 569
    HTML: 31
  • IncRNA MAPKAPK5-AS1 promotes proliferation and migration of thyroid cancer cell lines by targeting miR-519e-5p/YWHAH

    Yan Zhou, Shanshan Liu, Yan Luo, Meiying Zhang, Xueling Jiang, Yan Xiong
    03-12-2020
    https://doi.org/10.4081/ejh.2020.3177
    2131
    PDF: 886
    HTML: 13
  • MUC1 marks collecting tubules, renal vesicles, comma- and S-shaped bodies in human developing kidney

    D. Fanni, N. Iacovidou, A. Locci, C. Gerosa, S. Nemolato, P. Van Eyken, G. Monga, S. Mellou, G. Faa, V. Fanos
    e40
    26-10-2012
    https://doi.org/10.4081/ejh.2012.e40
    1562
    PDF: 650
    HTML: 353
  • Somatotrophs and lactotrophs: an immunohistochemical study of Gallus domesticus pituitary gland at different stages of induced moult

    M. A. Sandhu, Z. U. Rahman, A. Riaz, S. U. Rahman, I. Javed, N. Ullah
    e25
    19-05-2010
    https://doi.org/10.4081/ejh.2010.e25
    1205
    PDF: 1495
    HTML: 1399
  • 77 | TARGETING P75NTR CORRECTS OXIDATIVE AND INFLAMMATORY IMBALANCES IN A CELLULAR MODEL OF RETT SYNDROME M. Varone, M. Colardo, N. Martella, D. Pensabene, E. Bisesto, M. Segatto | Dept of Biosciences and Territory, University of Molise, Pesche, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4695
    15
    PDF: 8
  • P84 | OMOMYC PEPTIDE LOCALIZES IN THE NUCLEUS AND DISPLAYS ANTIPROLIFERATIVE EFFECTS ON CELLULAR MODELS OF HUMAN OSTEOSARCOMA I. Versari1, S. Salucci1, A. Bavelloni2, M. Traversari3, I. Faenza1 | 1Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy; 2Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; 3Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4410
    259
  • Atorvastatin reduces calcification in valve interstitial cells via the NF-κB signalling pathway by promoting Atg5-mediated autophagy

    Menghui Chen, Su Liu
    12-04-2024
    https://doi.org/10.4081/ejh.2024.3983
    1314
    PDF: 574
    HTML: 28
  • Image by <a href="https://pixabay.com/users/spotsoflight-6345617/?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=2744729">Monika Robak</a> from <a href="https://pixabay.com//?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=2744729">Pixabay</a>

    The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration

    Flavia Carton
    23-02-2023
    https://doi.org/10.4081/ejh.2023.3679
    1939
    PDF: 972
    HTML: 47
  • Ultrastructure and immunohistochemical characterization of proteins concerned with the secretory machinery in goat ceruminous glands

    Tadashi Yasui, Hiroshi Gomi, Taishi Kitahara, Azuma Tsukise
    08-08-2017
    https://doi.org/10.4081/ejh.2017.2828
    1825
    PDF: 698
    HTML: 154
  • Histochemistry in biology and medicine: a message from the citing journals

    Carlo Pellicciari
    23-12-2015
    https://doi.org/10.4081/ejh.2015.2610
    3176
    PDF: 870
    HTML: 895
  • microRNAs in development - Methods and protocols

    Manuela Monti
    br20
    24-11-2011
    https://doi.org/10.4081/ejh.2011.br20
    807
    PDF: 412
  • Can a genetically-modified organism-containing diet influence embryo development? A preliminary study on pre-implantation mouse embryos

    B Cisterna, F Flach, L Vecchio, SML Barabino, S Battistelli, TE Martin, M Malatesta, M Biggiogera
    263-267
    17-08-2009
    https://doi.org/10.4081/1226
    1508
    PDF: 940
  • Autophagy precedes apoptosis during degeneration of the Kölliker’s organ in the development of rat cochlea

    Shule Hou, Jiarui Chen, Jun Yang
    05-06-2019
    https://doi.org/10.4081/ejh.2019.3025
    1846
    PDF: 702
    HTML: 23
  • Elastofibroma dorsi: a histochemical and immunohistochemical study

    A. Di Vito, E. Scali, G. Ferraro, C. Mignogna, I. Presta, C. Camastra, C. Palmieri, G. Donato, T. Barni
    19-02-2015
    https://doi.org/10.4081/ejh.2015.2459
    2736
    PDF: 906
    HTML: 1099
  • Poly (ADP-ribose) polymerase 1 protein expression in normal and neoplastic prostatic tissue

    M. Salemi, A. Galia, F. Fraggetta, C. La Corte, P. Pepe, S. La Vignera, G. Improta, P. Bosco, A.E. Calogero
    e13
    15-04-2013
    https://doi.org/10.4081/ejh.2013.e13
    2911
    PDF: 3282
    HTML: 230
  • Fine distribution of CLOCK protein in hepatocytes of hibernating dormice

    M Malatesta, B Baldelli, L Rossi, S Serafini, G Gazzanelli
    233-240
    26-06-2009
    https://doi.org/10.4081/832
    724
    PDF: 568
  • SUMOYLATION AS AN EARLY ADAPTIVE MECHANISM IN THE PROTEOMIC RESPONSE OF HUMAN GERM CELLS TO SIMULATED MICROGRAVITY A. Di Pauli1, G. Ricci2, M. Crescenzi3, M. A. Mariggiò4, C. Morabito4, L. Gesualdi1, M. Berardini1, F. Ferranti5, M. Signore6, A. Catizone1 | 1Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, Section of Histology and Embryology, «Sapienza» University, Rome, Italy; 2Department of Experimental Medicine, University «Luigi Vanvitelli», Naples, Italy; 3Core Facilities, Italian National Institute of Health, Rome, Italy; 4Department of Neuroscience, Imaging and Clinical Sciences CAST, «G. d’Annunzio» University, Chieti, Italy; 5Human Spaceflight and Scientific Research Unit, Italian Space Agency, Rome, Italy; 6RPPA unit, Proteomics, Italian National Institute of Health, Rome, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4296
    201
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
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20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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