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Analysis of ERK3 intracellular localization: dynamic distribution during mitosis and apoptosis

F. Aredia, M. Malatesta, P. Veneroni, M.G. Bottone

01-12-2015

https://doi.org/10.4081/ejh.2015.2571

2584

PDF: 877

HTML: 809
Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou

22-06-2022

https://doi.org/10.4081/ejh.2022.3394

2275

PDF: 1458

HTML: 64
Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

16-12-2016

https://doi.org/10.4081/ejh.2016.2711

2794

PDF: 1251

HTML: 352
Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1619

PDF: 842

HTML: 59
Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps?

Antonella Vetuschi, Simon Pompili, Gian Piero Di Marco, Federico Calvaruso, Enz Iacomino, Lidia Angelosante, Claudio Festuccia, Alessandro Colapietro, Roberta Sferra

23-01-2020

https://doi.org/10.4081/ejh.2020.3079

2308

PDF: 1394

HTML: 53
Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu

11-05-2026

https://doi.org/10.4081/ejh.2026.4557

609

PDF: 1039

Supplementary: 78

HTML: 42
Analysis of extracellular superoxide dismutase and Akt in ascending aortic aneurysm with tricuspid or bicuspid aortic valve

A. Arcucci, M.R. Ruocco, F. Albano, G. Granato, V. Romano, G. Corso, C. Bancone, E. De Vendittis, A. Della Corte, S. Montagnani

18-07-2014

https://doi.org/10.4081/ejh.2014.2383

2527

PDF: 2353

HTML: 381
Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei

17-03-2014

https://doi.org/10.4081/ejh.2014.2263

4106

PDF: 1145

HTML: 649
Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRα) signal through MAPK/ERK pathway in human prostate tissues: a morphological and biomolecular study

Sonia Fantone, Giovanni Tossetta, Rodolfo Montironi, Martina Senzacqua , Daniela Marzioni, Roberta Mazzucchelli

19-10-2020

https://doi.org/10.4081/ejh.2020.3147

2307

PDF: 914

HTML: 58
Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

Jiapei Lv, Wang Yanting, Shan Wei

08-11-2023

https://doi.org/10.4081/ejh.2023.3867

2358

PDF: 1180

HTML: 98
E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei

26-05-2025

https://doi.org/10.4081/ejh.2025.4196

1699

PDF: 736

HTML: 59
Crocin exerts anti-tumor effect in colon cancer cells via repressing the JAK pathway

Hui Yang, Yunlong Zhang, Desheng Zhang, Liping Qian, Tianxing Yang, Xiaocheng Wu

12-09-2023

https://doi.org/10.4081/ejh.2023.3697

1541

PDF: 801

HTML: 51
Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li

21-01-2025

https://doi.org/10.4081/ejh.2025.4158

2072

PDF: 723

Supplementary Figure: 148

HTML: 91
Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy

Fenqiang Qi, Yuxin Deng, Wei Huang, Yanli Cai, Kelin Hong, Shui Xiang

15-10-2024

https://doi.org/10.4081/ejh.2024.4104

2693

PDF: 784

HTML: 51
SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang

18-05-2026

https://doi.org/10.4081/ejh.2026.4544

355

PDF: 385

Supplementary: 82

HTML: 41
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou

30-06-2025

https://doi.org/10.4081/ejh.2025.4221

1346

PDF: 613

HTML: 56
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

26-01-2026

https://doi.org/10.4081/ejh.2026.4422

879

PDF: 502

Supplementary: 105

Original gels: 118

HTML: 58
VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

Meiying Zhang, Min Zhou, Xia Cai, Yan Zhou, Xueling Jiang, Yan Luo, Yue Hu, Rong Qiu, Yanrong Wu, Yuejin Zhang, Yan Xiong

27-10-2022

https://doi.org/10.4081/ejh.2022.3522

2873

PDF: 1184

HTML: 87
Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin

23-10-2024

https://doi.org/10.4081/ejh.2024.4098

2822

PDF: 648

HTML: 64
PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNFα-CX3CR1 pathway

Xilei Li, Zhi Ye, Qulian Guo, E Wang, Yundan Pan

12-03-2021

https://doi.org/10.4081/ejh.2021.3184

2429

PDF: 1042

HTML: 55
Continuous cyclic mechanical tension increases ank expression in endplate chondrocytes through the TGF-Î²1 and p38 pathway

H. Xu, X. Zhang, H. Wang, Y. Zhang, Y. Shi, X. Zhang

e28

25-09-2013

https://doi.org/10.4081/ejh.2013.e28

2521

PDF: 763

HTML: 264
Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu

15-06-2026

https://doi.org/10.4081/ejh.2026.4569

323

PDF: 273

HTML: 52
Neurokinin-1 receptor is highly expressed in cervical cancer and its antagonist induces cervical cancer cell apoptosis

Liyun Guan, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang

11-01-2023

https://doi.org/10.4081/ejh.2023.3570

1685

PDF: 798

HTML: 59
Deubiquitinase USP14 is upregulated in Crohn's disease and inhibits the NOD2 pathway mediated inflammatory response in vitro

Mengling Li, Yan Zhao, Jiayi Zhang, Wang Jiang, Siyuan Peng, Jinyue Hu, Yueming Shen

09-09-2024

https://doi.org/10.4081/ejh.2024.4101

1555

PDF: 528

HTML: 41
MyD88/ERK/NFkB pathways and pro-inflammatory cytokines release in periodontal ligament stem cells stimulated by Porphyromonas gingivalis

Francesca Diomede, Maria Zingariello, Marcos F.X.B. Cavalcanti, Ilaria Merciaro, Jacopo Pizzicannella, Natalia de Isla, Sergio Caputi, Patrizia Ballerini, Oriana Trubiani

24-05-2017

https://doi.org/10.4081/ejh.2017.2791

3586

PDF: 1515

HTML: 185
Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang

08-09-2023

https://doi.org/10.4081/ejh.2023.3742

1466

PDF: 578

HTML: 65
Sinensetin ameliorates osteoarthritis progression by modulating the NF-κB/NLRP3 signaling pathway and suppressing chondrocyte pyroptosis

Zhendong Liu, Ruizhou Liu, Hongwei Yue, Peilai Liu, Rui Wang

07-10-2026

https://doi.org/10.4081/ejh.2026.4587

218

PDF: 155

HTML: 0
Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu

20-03-2023

https://doi.org/10.4081/ejh.2023.3639

1451

PDF: 879

HTML: 58
Downregulation of Williams syndrome transcription factor (WSTF) suppresses glioblastoma cell growth and invasion by inhibiting PI3K/AKT signal pathway

Liyuan Yang, Chunfu Du, Hui Chen, Zhengwen Diao

17-11-2021

https://doi.org/10.4081/ejh.2021.3255

1421

PDF: 761

HTML: 82
Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon

23-01-2017

https://doi.org/10.4081/ejh.2017.2749

6267

PDF: 1476

HTML: 440
STAT3 and SOCS3 expression patterns during murine placenta development

S. San Martin, J. Fitzgerald, M. Weber, M. PÃ¡rraga, T. SÃ¡ez, T.M. Zorn, U.R. Markert

e19

28-06-2013

https://doi.org/10.4081/ejh.2013.e19

3916

PDF: 989

HTML: 351
Curculigoside inhibits osteoarthritis via the regulation of NLRP3 pathway

Xufei Wang, Yinlian Liu, Yongnian Zhou, Yang Zhou, Yueping Li

13-12-2023

https://doi.org/10.4081/ejh.2023.3896

1652

PDF: 777

HTML: 58
Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng

03-09-2021

https://doi.org/10.4081/ejh.2021.3264

2271

PDF: 850

Supplementary: 214

HTML: 65
Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio

e40

04-12-2013

https://doi.org/10.4081/ejh.2013.e40

3927

PDF: 1130

HTML: 669
Co-transplantation of bone marrow mesenchymal stem cells and monocytes in the brain stem to repair the facial nerve axotomy

Li Wu, Dan Han, Jie Jiang, Xiaojie Xie, Xunran Zhao, Tengfei Ke, Wen Zhao, Liu Liu, Wei Zhao

19-06-2020

https://doi.org/10.4081/ejh.2020.3136

1861

PDF: 906

HTML: 50
Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio

19-10-2023

https://doi.org/10.4081/ejh.2023.3846

2010

PDF: 784

HTML: 73
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng

21-06-2022

https://doi.org/10.4081/ejh.2022.3412

2784

PDF: 1582

HTML: 59
Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

Arvis Pauliņš, Anna Junga, Māra Pilmane

10-02-2026

https://doi.org/10.4081/ejh.2026.4438

426

PDF: 571

HTML: 51
Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

V.N. Karavana, H. Gakiopoulou, E.A. Lianos

15-04-2014

https://doi.org/10.4081/ejh.2014.2308

2387

PDF: 1044

HTML: 681
Seasonal expressions of VEGF and its receptors VEGFR1 and VEGFR2 in the prostate of the wild ground squirrels (Spermophilus dauricus)

Yuchen Yao, Wenqian Xie, Di Chen, Yingying Han, Zhengrong Yuan, Haolin Zhang, Qiang Weng

24-03-2021

https://doi.org/10.4081/ejh.2021.3219

1702

PDF: 698

HTML: 78
Varying effects of EGF, HGF and TGFÎ² on formation of invadopodia and invasiveness of melanoma cell lines of different origin

A. Makowiecka, A. Simiczyjew, D. Nowak, A.J. Mazur

09-12-2016

https://doi.org/10.4081/ejh.2016.2728

2477

PDF: 1075

Supplementary: 352

HTML: 460
Assessment of the Selenoprotein M (SELM) over-expression on human hepatocellular carcinoma tissues by immunohistochemistry

E. Guerriero, M. Accardo, F. Capone, G. Colonna, G. Castello, S. Costantini

01-12-2014

https://doi.org/10.4081/ejh.2014.2433

4495

PDF: 931

HTML: 453
Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang

01-09-2025

https://doi.org/10.4081/ejh.2025.4217

696

PDF: 339

HTML: 42
LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu

31-05-2023

https://doi.org/10.4081/ejh.2023.3535

1443

PDF: 829

HTML: 81
Nuclear damages and oxidative stress: new perspectives for laminopathies

G. Lattanzi, S. Marmiroli, A. Facchini, N.M. Maraldi

e45

18-10-2012

https://doi.org/10.4081/ejh.2012.e45

2298

PDF: 1048

HTML: 242
Effects of chronic exposure to bisphenol A in adult female mice on social behavior, vasopressin system, and estrogen membrane receptor (GPER1)

Brigitta Bonaldo, Antonino Casile, Martina Bettarelli, Stefano Gotti, GianCarlo Panzica, Marilena Marraudino

10-11-2021

https://doi.org/10.4081/ejh.2021.3272

2563

PDF: 1206

HTML: 66
2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini

19-10-2021

https://doi.org/10.4081/ejh.2021.3276

3324

PDF: 1861

Video 1: 334

Video 2: 378

HTML: 54
Chemotherapy-induced nephrotoxicity was improved by crocin in mouse model

Qichao Yin, Hua Xiong

03-10-2022

https://doi.org/10.4081/ejh.2022.3541

1248

PDF: 783

HTML: 86
CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure

S. Huang, S. Guo, F. Guo, Q. Yang, X. Xiao, M. Murata, S. Ohnishi, S. Kawanishi, N. Ma

e1

14-01-2013

https://doi.org/10.4081/ejh.2013.e1

2354

PDF: 978

HTML: 926
The substance P and neurokinin-1 receptor system in human thyroid cancer: an immunohistochemical study

Inmaculada Isorna, Francisco Esteban, Juan Solanellas, Rafael Coveñas, Miguel Muñoz

28-04-2020

https://doi.org/10.4081/ejh.2020.3117

1524

PDF: 812

HTML: 42
miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan

07-12-2021

https://doi.org/10.4081/ejh.2021.3237

1938

PDF: 696

HTML: 65
Angiotensin II: immunohistochemical study in Sardinian pterygium

P. Demurtas, M. Corrias, I. Zucca, C. Maxia, F. Piras, P. Sirigu, M.T. Perra

28-07-2014

https://doi.org/10.4081/ejh.2014.2426

2327

PDF: 886

HTML: 390
Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao

26-07-2023

https://doi.org/10.4081/ejh.2023.3766

2473

PDF: 1511

HTML: 49
Effect of unacylated ghrelin on peripheral nerve regeneration

Giulia Ronchi, Pierluigi Tos, Elia Angelino, Luisa Muratori, Simone Reano, Nicoletta Filigheddu, Andrea Graziani, Stefano Geuna, Stefania Raimondo

04-11-2021

https://doi.org/10.4081/ejh.2021.3287

1939

PDF: 1074

HTML: 44
Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

25-08-2017

https://doi.org/10.4081/ejh.2017.2826

3319

PDF: 1436

HTML: 180
Investigating conversion of endplate chondrocytes induced by intermittent cyclic mechanical unconfined compression in three-dimensional cultures

H.G. Xu, W. Zhang, Q. Zheng, Y.F. Yu, L.F. Deng, H. Wang, P. Liu, M. Zhang

17-07-2014

https://doi.org/10.4081/ejh.2014.2415

1877

PDF: 1056

HTML: 407
Infection with CagA-positive Helicobacter pylori strain containing three EPIYA C phosphorylation sites is associated with more severe gastric lesions in experimentally infected Mongolian gerbils (Meriones unguiculatus)

M. Ferreira JÃºnior, S.A. Batista, P.V.T. Vidigal, A.A.C. Cordeiro, F.M.S. Oliveira, L.O. Prata, A.E.T. Diniz, C.M. Barral, R.C. Barbuto, A.D. Gomes, I.D. AraÃºjo, D.M.M. Queiroz, M.V. Caliari

27-04-2015

https://doi.org/10.4081/ejh.2015.2489

2358

PDF: 921

Supplementary: 391

HTML: 594
Expression of immediate-early genes in the inferior colliculus and auditory cortex in salicylate-induced tinnitus in rat

S.S. Hu, L. Mei, J.Y. Chen, Z.W. Huang, H. Wu

12-03-2014

https://doi.org/10.4081/ejh.2014.2294

3975

PDF: 1054

HTML: 666
Localization of CGRP and VEGF mRNAs in the mouse superior cervical ganglion during pre- and postnatal development

Kazuyuki Mitsuoka, Yoko Miwa, Takeshi Kikutani, Iwao Sato

22-11-2018

https://doi.org/10.4081/ejh.2018.2976

1907

PDF: 766

HTML: 104

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