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HOW DO THE CYTOSKELETON AND ITS BINDING PARTNERS CONTRIBUTE TO THE ESTABLISHMENT OF THE BRAIN MORPHOLOGY AND ITS FUNCTION? Sato M1,2,3 | 1Department of Anatomy and Neuroscience, Graduate School of Medicine, The University of Osaka, Japan; 2Molecular Brain Sciences, Department of Child Development, United Graduate School of Child Development-Osaka University, Kanazawa University, Hamamatsu University of Medicine, Chiba University and University of Fukui (UGSCD), The University of Osaka, Japan; 3Department of Neurosciences Rita Levi Montalcini, University of Turin, Italy
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P15 | PHB/JAK/H3Y41PH AXIS REGULATES MEIOTIC RECOMBINATION IN SPERMATOGENESIS H. Chen1, L. Zhang1, W. Tan-Tai1, M. Liu2, H. Shi3, W. O4, P.A. Martin-DeLeon5 | 1Department of Anatomy, Histology & Embryology, Shanghai Medical College, Fudan University, Shanghai, China; 2State Key Laboratory of Molecular Biology, Chinese Academy of Sciences-University of Chinese Academy of Sciences, Shanghai, China; 3NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China; 4School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China; 5Department of Biological Sciences, University of Delaware, Newark, USA
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THE ESTABLISHMENT OF A HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED IN VITRO MODEL TO STUDY DIABETIC PERIPHERAL NEUROPATHY Rando S1,2, Muratori L1,2, Contato A2,3, Lorenzati M2,3, Dotta S2,3, Marvaldi L2,3, Buffo A2,3 and Raimondo S1,2 | 1Department of Clinical and Biological Sciences, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi (NICO), Turin, Italy; 3Department of Neuroscience “Rita Levi Montalcini” University of Turin, Turin, Italy
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Reliable hexokinase 3 protein detection in human cell lines and primary tissue
1832PDF: 433Supplementary: 53Uncropped Western blots: 50HTML: 10 -
PATHOMICS – A NOVEL OMICS APPROACH FOR HISTOPATHOLOGY P. Boor1,2 | 1Institute of Pathology, RWTH Aachen University Hospital, Aachen, Germany; Electron Microscopy Facility, RWTH Aachen University Hospital, Aachen, Germany; 2Division of Nephrology and Immunology, RWTH Aachen University Hospital, Aachen, Germany
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CRAFTING THE MICROVASCULAR CANVAS: BIOENGINEERED MATERIALS OR NATIVE EXTRACELLULAR MATRIX FOR THE CENTRAL NERVOUS SYSTEM De Luca C1, Virtuoso A1, Cirillo G1, De Angelis F1, Guedán A2, Maduna T3, Morin A4, Sepulveda Diaz J4, Vlachos A3,5,6, Panetsos F7, Pérez-Rigueiro J8 and Papa M1,9 | 1Laboratory of Morphology of Neuronal Networks and Systems Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; 2Bioactive Surfaces S.L., Madrid, Spain; 3Department of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany; 4Microfluidics Innovation Center, Paris, France; 5Center for Basics in Neuromodulation (NeuroModulBasics), Faculty of Medicine. University of Freiburg, Freiburg, Germany 6Center BrainLinks-BrainTools, University of Freiburg, Freiburg, Germany; 7Universidad Complutense de Madrid, Madrid, Spain 8Universidad Politécnica de Madrid, Spain; 9SYSBIO Centre of Systems Biology ISBE-IT, Milan, Italy
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Varying effects of EGF, HGF and TGFβ on formation of invadopodia and invasiveness of melanoma cell lines of different origin
2246PDF: 933Supplementary: 284HTML: 415 -
PRENATAL N-ACETYL-CYSTEINE PREVENTS NEURONAL, EMOTIONAL AND METABOLIC IMPAIRMENTS IN AN ANIMAL MODEL OF ADVERSE EXPERIENCES Cirulli F | Center for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy
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P31 | MORPHOLOGICAL AND ULTRASTRUCTURAL MARKERS OF RADIATION-INDUCED ADIPOSE TISSUE DAMAGE E. Guerra1, S. Lattanzio1, G. Furini2, G. Scabia2, E. Mota-Silva2, M. Maffei2, S. Cinti3, R. Di Pietro1 | 1Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2CNR Institute of Clinical Physiology, Pisa, Italy; 3Department of Experimental and Clinical Medicine, Center of Obesity, Università Politecnica delle Marche (Polytechnic University of Marche), Ancona, Italy
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Sox9 expression in canine epithelial skin tumors
3118PDF: 858HTML: 406 -
MITOCHONDRIAL DYSFUNCTION AS A KEY FACTOR OF MOTOR NEURON DEGENERATION: INSIGHTS FROM AMYOTROPHIC LATERAL SCLEROSIS CELLULAR MODELS Scimia N¹, Carletti RM², Rasà MD¹, Ferrari D3, Boido M¹ and Stanga S¹ | ¹Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; ²Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; 3Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
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Expression of S100β during mouse cochlear development
1363PDF: 362Supplementary: 68HTML: 6 -
Elastofibroma dorsi: a histochemical and immunohistochemical study
2681PDF: 874HTML: 1097 -
HACAT CELLS AS A 2D EXPERIMENTAL DIFFERENTIATING MODEL TO ANALYZE THE EARLY BIOLOGICAL EFFECTS INDUCED BY A PSORIATIC PROINFLAMMATORY MICROENVIRONMENT: CELL PROLIFERATION, DIFFERENTIATION AND FERROPTOSIS F. Riva1, S. Recalcati2, E. Gammella2, D. Daluiso1, F. Prignano3, E. Donetti2 | 1Dept. Public Health, Experimental and Forensic Medicine; Histology and Embryology Unit, University of Pavia, Pavia, Italy; 2Dept. Biomedical Sciences for Health, University of Milan, Milan, Italy; 3Dept. Health Sciences, Section of Dermatology, University of Florence, Florence, Italy
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OVEREXPRESSION OF ANOSMIN-1 ALTERS THE MYELINATION PATTERN AND THE MORPHOLOGY OF AXONAL COMPONENTS IN CEREBELLAR PURKINJE CELLS Fieromonte A1, Lorenzati M1, Staffa A2, Bribian A2, Barderas MG3, Aguilar J4, De Castro F2 and Buffo A1 | 1Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Turin, Department of Neuroscience ita Levi, Montalcini, Turin, Italy; 2Instituto Cajal-CSIC, Grupo de Neurobiologia del Desarrollo-GNDe, Madrid, Spain; 3Servicio de Salud de Castilla- La Mancha-SESCAM, Department of Vascular Physiopathology, Hospital Nacional de Paraplejicos, Toledo, Spain; 4Servicio de Salud de Castilla-La Mancha-SESCAM, Experimental Neurophysiology Group, Hospital Nacional de Paraplejicos, Toledo, Spain
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Lorenzo Gotte (1926-1991): a pioneer of elastin
1385PDF: 676HTML: 204 -
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NEUROBIOLOGY OF SUICIDE: MORPHOLOGICAL ASSESSMENT OF MICROGLIAL NETWORK IN HUMAN POST-MORTEM PREFRONTAL CORTEX Tambuzzi S1, Bertolotto N2, Massari S2, Madaschi L3, Alini M2, Brandolese D2, Ubezio MC1, Cattaneo C1 and Amadeo A2 | 1Institute of Forensic Medicine, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; 2Department of Biosciences, Università degli Studi di Milano, Milan, Italy; 3UNITECH NOLIMITS, Università degli Studi di Milano, Milan, Italy
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P41 | INVOLVEMENT OF THE DOLPHIN’S MELON IN IMMUNE FUNCTION G.P. Lombardo1, A. Miller2, L. Spiccia1, V. Natale1, F. Pellicanò1, G. Squadrito1, E. R. Lauriano1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina; 2Department of Veterinary Sciences, University of Messina, Messina, Italy
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FROM CLOUD TO BEDSIDE C. Tacchetti1,2 | 1Medical School & S.RACE (San-Raffaele Artificial Intelligence Center);Vita-Salute University San Raffaele, Milan, Italy; 2Experimental Imaging Center, IRCCS Hospital San Raffaele, Milan, Italy
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CHEMOTHERAPY-INDUCED REMODELING OF CORTICAL PYRAMIDAL NEURONS: MORPHOLOGICAL EFFECTS OF OXALIPLATIN AND PACLITAXEL Iezzi G1,2, Marmiroli P3,4, Vercelli A1,2 and Cavaletti G3,4 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi,Turin, Italy; 3University of Milano-Bicocca, Italy; 4Experimental Neurology Unit, Monza, Italy
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Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway
1325PDF: 896Supplementary: 89HTML: 21 -
Merkel cell distribution in the human eyelid
2621PDF: 584HTML: 96 -
An improved method for preparation of mouse retinal cryosections
2260PDF: 1382Supplementary: 180HTML: 515 -
A PRECLINICAL STUDY ON THE MODULATION OF THE MICROBIOTA–GUT–BRAIN AXIS BY A FUNCTIONAL SNACK PROMOTING HEALTHY AGING Bellitto V1, Grasselli F1, Martinelli I2, Nittari G2, Vittadini E1, Eleuteri AM1, Tayebati SK2, Bonfili L1 and Tomassoni D1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal and Health Products Sciences, University of Camerino, Italy
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P43 | NEW INSIGHTS IN THE ACTIVATION OF FERROPTOSIS PROCESS DURING LIVER FIBROSIS R. Mancinelli1, S. Leone1, A. Casini1, R. Vaccaro1, M. Tagliafierro1, F.M. Bassi1, E. Bocci1, S. Vitale1, A. Franchitto2, L. Pannarale1, P. Onori1, E. Gaudio1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; 2Division of Health Sciences, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, Italy
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CONNEXIN 43 HEMICHANNELS CAN DRIVE THE GLIOBLASTOMA SPREADING Virtuoso A1, De Luca C1, Altieri R2, Milior G3, Moulard J3, Huberfeld J3, Cirillo G1, Barbarisi M2, Rouach N3 and Papa M1 | 1Laboratory of Neural Network Morphology and Systems Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; 2Multidisciplinary Department of Medical, Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy; 3Interdisciplinary Research Center in Biology, College de France, CNRS, INSERM, Labex Memolife, Université PSL, Paris, France
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Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway
1743PDF: 564Supplementary Figure: 79HTML: 53 -
BEYOND THE SPINAL CORD: MORPHOLOGICAL ALTERATIONS OF CORTICAL PROJECTION NEURON IN SPINAL MUSCULAR ATROPHY La Rocca F1,2, Schellino R1,2, Iezzi G1,2, Caretto A1,2, Boido B1,2 and Vercelli A1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri, Ottolenghi, University of Turin, Turin, Italy
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Cartilage canals in newborn dogs: histochemical and immunohistochemical findings
1460PDF: 713Supplementary: 290HTML: 215 -
Expression of nestin, parvalbumin and otoferlin during cochlear development in the mouse: an immunofluorescence study
551PDF: 414Supplementary: 43HTML: 8 -
EX VIVO MAPPING OF NIGRO-THALAMIC DOPAMINERGIC TERMINALS REVEALS REGIONAL SPECIALIZATION AND SYNAPTIC MARKERS IN THE HUMAN THALAMUS Cirillo G1, Montella M2, La Mantia E2, Tedesco I2, De Luca C1, Virtuoso A1, De Angelis F1, Riccio L1, Esposito F3, Cirillo M3, Franco R2 and Papa M1 | 1Division of Human Anatomy, Neuronal Networks Morphology & Systems Biology Lab, Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli, Naples, Italy; 2Division of Pathology, Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli, Naples, Italy; 3Department of Advanced Medical and Surgical Sciences, Advanced MRI Research Center, University of Campania Luigi Vanvitelli, Naples, Italy
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P48 | NEW STRATEGIES TO IMPROVE THE RESPONSE OF AML CELLS TO TARGETED THERAPIES BY OVERCOMING THE PROTECTIVE EFFECT OF THE BONE MARROW MESENCHYMAL STEM CELLS G. Mazzanti1, F. Liccardo2, L. Pace1, M. Marcotulli3, L. Lafrate3, G. Cidonio3, T. Ottone4, S. Travaglini4, M.T. Voso4, V. Fulci5, M. Sampaolesi1, F. Fazi1, S. Masciarelli1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences and Medical Embryology, Section of Histology Sapienza University of Rome, Rome, Italy; 2Centre de Recherches en Cancérologie de Toulouse, Inserm/ U1037, Université de Toulouse, Toulouse, France; 3Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, Rome, Italy; 4Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy; 5Department of Molecular Medicine, Sapienza, University of Rome, Rome, Italy
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