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Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species
2278PDF: 1195Supplementary: 110HTML: 168 -
Aging and Health - A system biology perspective
1263PDF: 567HTML: 85 -
Expression of S100β during mouse cochlear development
1469PDF: 401Supplementary: 76HTML: 9 -
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On the future contents of a small journal of histochemistry
2573PDF: 985HTML: 942 -
13 | MULTI-OMICS DISSECTION OF TRANSCRIPTIONAL AND EPIGENETIC REMODELING DURING CARDIAC AGING Daniele Bonisolo1, Simone Serio2, Christina Pagiatakis1|2, Rosalba Gornati1, Giovanni Bernardini1, Roberto Papait1|2 | 1Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy; 2Department of Cardiovascular Medicine, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy
166PDF: 19 -
Morphological and ultrastructural analysis of normal, injured and osteoarthritic human knee menisci
2743PDF: 1359Supplementary: 243HTML: 56 -
08 | HUMAN ADIPOSE STEM CELLS: IMPACT OF DONORS’ AGE ON CELL PROPERTIES AND BEHAVIOUR Ludovica Barone1, Federica Rossi1, Federico Tamborini1, Christina Pagiatakis1|2, Roberto Papait1|2, Rosalba Gornati1 | 1Dept of Biotechnology and Life Sciences, University of Insubria, Varese, Italy; 2Dept of Cardiovascular Medicine, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy
179PDF: 15 -
Long noncoding RNA H19 accelerates tenogenic differentiation by modulating miR-140-5p/VEGFA signaling
1868PDF: 962Supplementary: 171HTML: 27 -
ON THE WAY TO A NEW MODEL OF NEURODEGENERATION? FIRST EVIDENCE OF THE EXPRESSION OF GATA1 IN THE BRAIN: CORRELATIONS WITH AGING, MITOCHONDRIAL DAMAGE AND SYNUCLEINOPATHY C. Caturano1, F. E. Bellomi1, F. Arciprete1, V. Velardi1, L. La Barbera2, M. Falchi3, M. Bacioglu4, R. Mancinelli5, M. D’Amelio2, M. Spillantini4, M. Zingariello1, G. Vivacqua1,6 | 1Laboratory of Microscopic and Ultrastructural Anatomy, Campus Biomedico University of Rome, Italy; 2Laboratory of Molecular Neuroscience - Campus Biomedico University of Rome, Italy; 3National Centre for HIV/AIDS Research, Istituto Superior di Sanità, Rome, Italy; 4Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK; 5Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy; 6Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK
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THE CHEMISTRY OF NUTRACEUTICALS: DRIVING HEALTH INNOVATIONS AND SHAPING NEW PARADIGMS M. Micucci | Department of Biomolecular Sciences, Urbino University “Carlo Bo”, Urbino, Italy
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Mouse development - From oocyte to stem cells
2282PDF: 617HTML: 112 -
30 | NANO-COMPUTED TOMOGRAPHY 3D MAPPING OF PRIMARY-TO-PREOVULATORY FOLLICLES IN THE MOUSE OVARY ACROSS LIFESPAN G. Fiorentino1|9, A. Fantinato1|9, A. Parrilli2, T. Marzi3, C. Alippi3|4, R. Bellazzi5, L. Rienzi6|7, F.M. Ubaldi8, A. Vaiarelli8, G. Brazzale1, V. Merico1, P. Rebuzzini1, D. Cimadomo1|7, S. Garagna1, M. Zuccotti1 | 1Dept. of Biology and Biotechnology, University of Pavia, Italy; 2Empa-Swiss Federal Laboratories for Materials Science and Technology, Switzerland; 3Faculty of Informatics, Università della Svizzera italiana, Switzerland; 4Dept. of Electronics, Information, and Bioengineering, Politecnico di Milano, Italy; 5Dept. of Computer, Electrical and Biomedical Engineering, University of Pavia, Italy; 6Dept. of Biomolecular Sciences, University of Urbino, Italy; 7IVIRMA Global Research Alliance, IVIRMA Italia, Italy; 8IVIRMA Global Research Alliance, Clinica Valle Giulia, Italy; 9Equal contribution
84PDF: 13 -
A PILOT STUDY TO INVESTIGATE THE ANTIAGING EFFECTS OF THE OLIVE POMACE BY-PRODUCT ON THE BRAIN OF DROSOPHILA MELANOGASTER Makladissi S1†, Tomassoni D2†*, Nardin T3, Bellitto V2, Cappelli A2, Di Cara F1‡ and Beghelli D2‡ | 1Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada; 2School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, MC, Italy ; 3Chemical Unit Oenological Vines Agri-food - Technology Transfer Centre Foundation Edmund Mach, TN, Italy †These authors equally contributed. ‡These authors share the authorship
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ALPHA SYNUCLEIN REGULATION IN BRAIN AND BONE MARROW IS RELETED TO THE DIFFERENTIAL EXPRESSION OF GATA1 TRANSCRIPTION FACTOR Velardi V1, Arciprete F1, Caturano C1, Rana RA1, Mancinelli R2, Zingariello M1 and Vivacqua G1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy
259 -
Expression of nestin, parvalbumin and otoferlin during cochlear development in the mouse: an immunofluorescence study
604PDF: 537Supplementary: 53HTML: 12 -
P20 | RNASEQ AND HISTOCHEMICAL STAININGS ASSESS BIOCHEMICAL AND STRUCTURAL CHANGES IN THE MOUSE INTERVERTEBRAL DISC ACROSS THE LIFESPAN A. Hallmark1, A. Ali2, C. Dahia3 | 1Hospital for Special Surgery, New York, USA; 2Department of Medicine, Columbia University, New York, USA; 3Hospital for Special Surgery, Weill Cornell Medicine
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Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway
1865PDF: 595Supplementary Figure: 91HTML: 61 -
THE LINK BETWEEN NEURONAL BRANCHING AND PAIN Dotta S1, Muraglia L1, Musso G1, Rother F2,3, Pritz. C1, Luzzati F1, Bader M2,3,4, Buffo A1, Vercelli A1 and Marvaldi L1 | 1Department of Neuroscience Rita Levi Montalcini, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Orbassano (TO), Italy; 2Max Delbrück Center for Molecular Medicine, Berlin, Germany; 3Center for Structural and Cellular Biology in Medicine, Institute of Biology, University of Lübeck, Germany; 4Charité, Universitätsmedizin, Berlin, Germany
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Elastofibroma dorsi: a histochemical and immunohistochemical study
2773PDF: 916HTML: 1100 -
P44 | CROSSTALK AMONG NEURONS, MUSCLE AND BONE: HUMAN NEUROMUSCULAR JUNCTION ON A CHIP M. Gatti1,2, F. Beretti2, M. Malenchini2, M. Y. Follo1, F. Mancarella3, F. Bonafè3, F. Gherardini4, T. Maraldi2 | 1Department of Biomedical and Neuromotor Science, Cellular Signalling Laboratory, University of Bologna, Italy; 2Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy; 3Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), National Research Council (CNR), Bologna, Italy; 4Department of Engineering “Enzo Ferrari”, University of Modena and Reggio Emilia, Modena, Italy
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GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location
3559PDF: 588Supplementary: 229HTML: 32 -
PO54 | FATTY INFILTRATION AND POTENTIAL ADIPOGENIC SHIFT OF SKELETAL MUSCLE CELLS: MULTIPARAMETRIC HISTOLOGICAL ANALYSIS OF MYOSTEATOSIS L. Morello1, G. Stati1, V. Giansante1, S. Lattanzio1, P. Cerritelli1, D. Bruni1, S. Cinti2, R. Di Pietro1,3,4 | 1Department of Medicine and Aging Sciences, “G. d’ Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Experimental and Clinical Medicine, Center of Obesity, Polytechnic University of Marche, Ancona, Italy; 3StemTeCh Group, G. d’ Annunzio Foundation, “G. d’ Annunzio” University of Chieti Pescara, Chieti, Italy; 4Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA
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GLIAL INFLAMMASOME ACTIVATION AND BLOOD-BRAIN BARRIER BREAKDOWN IN AGE-RELATED NEURODEGENERATION Errede M1, Girolamo F1, d’Amati A1,2, de Giorgis M1, Lorusso L1, Pierucci C3, Bernardini N3, Pellegrini C3, Virgintino D1 and Annese T2 | 1University of Bari, Department of Translational Biomedicine and Neuroscience – Human Anatomy and Histology Unit, Bari, Italy; 2Libera Università del Mediterraneo (LUM) Giuseppe Degennaro University, Department of Medicine and Surgery, Bari, Italy; 3University of Pisa, Department of Clinical and Experimental Medicine - Unit of Histology and Medical Embryology, Pisa, Italy
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Developmental expression of calretinin in the mouse cochlea
1748PDF: 588HTML: 19 -
A PRECLINICAL STUDY ON THE MODULATION OF THE MICROBIOTA–GUT–BRAIN AXIS BY A FUNCTIONAL SNACK PROMOTING HEALTHY AGING Bellitto V1, Grasselli F1, Martinelli I2, Nittari G2, Vittadini E1, Eleuteri AM1, Tayebati SK2, Bonfili L1 and Tomassoni D1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal and Health Products Sciences, University of Camerino, Italy
310 -
P18 | NESTIN EXPRESSION IN THE MYOCARDIUM OF SPONTANEOUSLY HYPERTENSIVE RATS AND CONPLASTIC SHR-MTBN STRAIN, AND CO-EXPRESSION WITH CONNEXIN 43 D. Cizkova1, J. M. Zurmanova2, T. Artykov1, F. Galatik2, B. Elsnicova2, J. Silhavy3, M. Pravenec3, J. Mokry1 | 1Department of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic; 2Department of Physiology, Faculty of Science, Charles University, Prague, Czech Republic; 3Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic
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A NOVEL DRUG TARGETTING THE INFLAMMASOME AMELYORATES AD PATHOLOGY IN THE MURINE MODEL 5xFAD Chicote J1, Rosano V1, Mezzanotte M1, Bertinaria M2, Marini E2, Vercelli A1 and Stanga S1 | 1Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; 2Department of Drug Science and Technology, University of Turin, Italy
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PARP-1 protein expression in glioblastoma multiforme
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LABELING EXTRACELLULAR VESICLES FOR HIGHLY SENSITIVE FLOW CYTOMETRY ANALYSES P. Simeone1,2, D. Brocco3, F. D’Ascanio1,2,4, D. De Bellis1,2, G. Colasante1,2, A. Aquilini-Mummolo1,2, T. Esmail1,2, A. Younas2, M. Filoso2, C. Cichella2, M. C. Cufaro5, A. Di Sebastiano5, D. Pieragostino6, S. Burattini7, M. Battistelli7, P. Del Boccio5, A. Fontana8, R. Di Pietro1, P. Lanuti1,2 | 1Department of Medicine and Aging Sciences, University “G. d’Annunzio” of Chieti-Pescara, Italy; 2Flow Cytometry Core Facility, Center for Advanced Studies and Technology (CAST), University “G. d’Annunzio” of Chieti-Pescara, Italy; 3Department of Medical, Oral and Biotechnological Sciences, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy; 4Department of Humanities, Law and Economics, Leonardo da Vinci University, Torrevecchia Teatina, Italy: 5Department of Science, University “G. d’Annunzio”, Chieti Pescara, Italy; 6Department of Innovative Technologies in Medicine and Dentistry, G. d’Annunzio University of Chieti-Pescara, Italy; 7Department of Biomolecular Sciences, University of Urbino, Urbino, Italy; 8Department of Pharmacy, University “G. d’Annunzio”, Chieti Pescara, Italy
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