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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Human dental pulp stem cells produce mineralized matrix in 2D and 3D cultures

    M. Riccio, E. Resca, T. Maraldi, A. Pisciotta, A. Ferrari, G. Bruzzesi, A. De Pol
    e46
    10-11-2010
    https://doi.org/10.4081/ejh.2010.e46
    2099
    PDF: 908
    HTML: 8673
  • Determination of cell fate in skeletal muscle following BMP gene transfer by in vivo electroporation

    Mariko Kawai, Yu-Ki Ohmori, Mai Nishino, Masayo Yoshida, Kaori Tabata, Do-Saku Hirota, Ayako Ryu-Mon, Hiromitsu Yamamoto, Junya Sonobe, Yo-Hei Kataoka, Noriko Shiotsu, Mika Ikegame, Hiroki Maruyama, Toshio Yamamoto, Kazuhisa Bessho, Kiyoshi Ohura
    05-05-2017
    https://doi.org/10.4081/ejh.2017.2772
    1976
    PDF: 734
    HTML: 198
  • Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

    Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou
    22-06-2022
    https://doi.org/10.4081/ejh.2022.3394
    1823
    PDF: 1197
    HTML: 26
  • Ultrastructural analysis of different human mesenchymal stem cells after in vitro expansion: a technical review

    M. Miko, L. Danisovic, A. Majidi, I. Varga
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2528
    2506
    PDF: 830
    HTML: 833
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    2869
    PDF: 1133
    Supplementary: 363
    HTML: 1013
  • Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea

    Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong
    01-09-2023
    https://doi.org/10.4081/ejh.2023.3704
    1091
    PDF: 791
    HTML: 20
  • Expression of CGRP, vasculogenesis and osteogenesis associated mRNAs in the developing mouse mandible and tibia

    Yuuki Maeda, Yoko Miwa, Iwao Sato
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2750
    2237
    PDF: 947
    HTML: 462
  • Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

    Nan Li, Xue Fan, Lihong Liu, Yanbing Liu
    27-07-2023
    https://doi.org/10.4081/ejh.2023.3506
    1561
    PDF: 968
    HTML: 19
  • Histochemical and morphological aspects of fresh frozen bone: a preliminary study

    F.S. De Ponte, G. Cutroneo, R. Falzea, G. Rizzo, L. Catalfamo, A. Favaloro, G. Vermiglio, M. Runci, A. Centofanti, G. Anastasi
    06-12-2016
    https://doi.org/10.4081/ejh.2016.2642
    1467
    PDF: 594
    HTML: 151
  • Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

    Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang
    01-08-2023
    https://doi.org/10.4081/ejh.2023.3784
    1815
    PDF: 814
    HTML: 20
  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2048
    PDF: 1053
    Supplementary: 99
    HTML: 99
  • Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

    Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li
    25-10-2022
    https://doi.org/10.4081/ejh.2022.3529
    1602
    PDF: 772
    HTML: 36
  • The hematopoietic stem cells supportive megakaryocytes as shapers of the bone marrow niche

    Francesca Arciprete, Viola Velardi, Paola Verachi, Claudio Carta, Antonio Di Virgilio, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello
    16-12-2025
    https://doi.org/10.4081/ejh.2025.4424
    553
    PDF: 238
    HTML: 7
  • What happens to an acellular dermal matrix after implantation in the human body? A histological and electron microscopic study

    Martin Boháč, Ľuboš Danišovič, Ján Koller, Jana Dragúňová, Ivan Varga
    22-01-2018
    https://doi.org/10.4081/ejh.2018.2873
    3215
    PDF: 1364
    HTML: 97
  • DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

    Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3413
    1189
    PDF: 617
    Supplementary: 91
    HTML: 20
  • Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

    Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié
    21-08-2025
    https://doi.org/10.4081/ejh.2025.4174
    480
    PDF: 287
    HTML: 15
  • Umbilical cord mesenchymal stem cells inhibited inflammation of bronchial epithelial cells by regulating Hedgehog pathway

    Qiong Lin, Tianxing Yu, Xiaohua Li, Xin Lin, Yong Fan, Liyu Xu
    12-12-2023
    https://doi.org/10.4081/ejh.2023.3908
    1510
    PDF: 471
    HTML: 21
  • microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

    Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu
    10-05-2022
    https://doi.org/10.4081/ejh.2022.3333
    1617
    PDF: 866
    HTML: 27
  • The knee joint loose body as a source of viable autologous human chondrocytes

    J. Melrose
    10-06-2016
    https://doi.org/10.4081/ejh.2016.2645
    2226
    PDF: 753
    HTML: 401
  • Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

    Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani
    25-08-2017
    https://doi.org/10.4081/ejh.2017.2826
    3007
    PDF: 1252
    HTML: 136
  • MyD88/ERK/NFkB pathways and pro-inflammatory cytokines release in periodontal ligament stem cells stimulated by Porphyromonas gingivalis

    Francesca Diomede, Maria Zingariello, Marcos F.X.B. Cavalcanti, Ilaria Merciaro, Jacopo Pizzicannella, Natalia de Isla, Sergio Caputi, Patrizia Ballerini, Oriana Trubiani
    24-05-2017
    https://doi.org/10.4081/ejh.2017.2791
    3136
    PDF: 1342
    HTML: 148
  • The trochanteric fat pad

    P. Panettiere, D. Accorsi, L. Marchetti, A.M. Minicozzi, G. Orsini, P. Bernardi, D. Benati, G. Conti, A. Sbarbati
    e16
    24-05-2011
    https://doi.org/10.4081/ejh.2011.e16
    2395
    PDF: 680
    HTML: 7457
  • Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

    Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai
    14-10-2022
    https://doi.org/10.4081/ejh.2022.3510
    1231
    PDF: 658
    HTML: 33
  • Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally

    Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariotti
    04-07-2024
    https://doi.org/10.4081/ejh.2024.4040
    1939
    PDF: 550
    HTML: 18
  • In vitro reparative dentin: a biochemical and morphological study

    G. Teti, V. Salvatore, A. Ruggeri, L. Manzoli, M. Gesi, G. Orsini, M. Falconi
    e23
    06-08-2013
    https://doi.org/10.4081/ejh.2013.e23
    3187
    PDF: 796
    HTML: 934
  • Decellularized omentum as novel biologic scaffold for reconstructive surgery and regenerative medicine

    A. Porzionato, M. M. Sfriso, V. Macchi, A. Rambaldo, G. Lago, L. Lancerotto, V. Vindigni, R. De Caro
    e4
    24-01-2013
    https://doi.org/10.4081/ejh.2013.e4
    2293
    PDF: 979
    HTML: 1084
  • Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

    Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li
    21-01-2025
    https://doi.org/10.4081/ejh.2025.4158
    1689
    PDF: 547
    Supplementary Figure: 65
    HTML: 51
  • Subcutaneous adipose tissue classification

    A. Sbarbati, D. Accorsi, D. Benati, L. Marchetti, G. Orsini, G. Rigotti, P. Panettiere
    e48
    25-11-2010
    https://doi.org/10.4081/ejh.2010.e48
    3629
    PDF: 1304
    HTML: 2615
  • Organotypic spinal cord cultures: An in vitro 3D model to preliminary screen treatments for spinal muscular atrophy

    Marina Boido, Elena De Amicis, Katia Mareschi, Franca Fagioli, Alessandro Vercelli
    04-11-2021
    https://doi.org/10.4081/ejh.2021.3294
    2138
    PDF: 847
    HTML: 24
  • LOX-1 deficient mice show resistance to zymosan-induced arthritis

    Kazuhiko Hashimoto, Yutaka Oda, Koichi Nakagawa, Terumasa Ikeda, Kazuhiro Ohtani, Masao Akagi
    22-01-2018
    https://doi.org/10.4081/ejh.2018.2847
    1978
    PDF: 847
    HTML: 74
  • Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study

    A. Santoro, G. Pannone, M.E. Errico, D. Bifano, G. Lastilla, P. Bufo, C. Loreto, V. Donofrio
    e25
    02-07-2012
    https://doi.org/10.4081/ejh.2012.e25
    1472
    PDF: 586
    HTML: 5385
  • Bone morphogenetic protein-4 and bone morphogenetic protein receptors expressions in the adult rat eye

    Yuka Maruyama-Koide, Sumiko Mikawa, Takeshi Sasaki, Kohji Sato
    06-09-2017
    https://doi.org/10.4081/ejh.2017.2797
    1315
    PDF: 662
    HTML: 58
  • High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

    Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos
    17-02-2022
    https://doi.org/10.4081/ejh.2022.3360
    2416
    PDF: 937
    HTML: 37
  • Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

    C. Pellicciari
    e51
    16-12-2010
    https://doi.org/10.4081/ejh.2010.e51
    1426
    PDF: 711
    HTML: 3881
  • Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study

    M. Di Rosa, M.A. Szychlinska, D. Tibullo, L. Malaguarnera, G. Musumeci
    16-09-2014
    https://doi.org/10.4081/ejh.2014.2423
    2877
    PDF: 1137
    HTML: 1607
  • Treatment of diabetic foot ulcers with Therapeutic Magnetic Resonance (TMR®) improves the quality of granulation tissue

    Letizia Ferroni, Chiara Gardin, Andrea De Pieri, Maria Sambataro, Elena Seganfreddo, Chiara Goretti, Elisabetta Iacopi, Barbara Zavan, Alberto Piaggesi
    07-08-2017
    https://doi.org/10.4081/ejh.2017.2800
    2166
    PDF: 990
    HTML: 126
  • Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

    Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4182
    1070
    PDF: 636
    HTML: 36
  • Development of synovial membrane in the temporomandibular joint of the human fetus

    L.O. Carvalho de Moraes, R.C. Tedesco, L.A. Arraez-Aybar, O. Klein, J.R. Mérida-Velasco, L.G. Alonso
    26-11-2015
    https://doi.org/10.4081/ejh.2015.2569
    2912
    PDF: 876
    HTML: 770
  • Long noncoding RNA H19 accelerates tenogenic differentiation by modulating miR-140-5p/VEGFA signaling

    You-Jie Liu, Hua-Jun Wang, Zhao-Wen Xue, Lek-Hang Cheang, Man-Seng Tam, Ri-Wang Li, Jie-Ruo Li, Hui-Ge Hou, Xiao-Fei Zheng
    07-09-2021
    https://doi.org/10.4081/ejh.2021.3297
    1716
    PDF: 911
    Supplementary: 152
    HTML: 22
  • MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

    Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3426
    1393
    PDF: 786
    HTML: 25
  • Three-dimensional scaffold-free fusion culture: the way to enhance chondrogenesis of in vitro propagated human articular chondrocytes

    M. Lehmann, F. Martin, K. Mannigel, K. Kaltschmidt, U. Sack, U. Anderer
    e31
    05-11-2013
    https://doi.org/10.4081/ejh.2013.e31
    4767
    PDF: 1037
    HTML: 964
  • Nuclear damages and oxidative stress: new perspectives for laminopathies

    G. Lattanzi, S. Marmiroli, A. Facchini, N.M. Maraldi
    e45
    18-10-2012
    https://doi.org/10.4081/ejh.2012.e45
    1995
    PDF: 868
    HTML: 200
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3325
    PDF: 842
    HTML: 408
  • Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

    Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno
    15-03-2018
    https://doi.org/10.4081/ejh.2018.2841
    14084
    PDF: 6913
    HTML: 409
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2244
    PDF: 660
    HTML: 807
  • Is there still room for novelty, in histochemical papers?

    Carlo Pellicciari
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2758
    2721
    PDF: 695
    HTML: 279
  • Investigating conversion of endplate chondrocytes induced by intermittent cyclic mechanical unconfined compression in three-dimensional cultures

    H.G. Xu, W. Zhang, Q. Zheng, Y.F. Yu, L.F. Deng, H. Wang, P. Liu, M. Zhang
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2415
    1678
    PDF: 759
    HTML: 370
  • On the future contents of a small journal of histochemistry

    C. Pellicciari
    e51
    10-12-2012
    https://doi.org/10.4081/ejh.2012.e51
    2430
    PDF: 947
    HTML: 938
  • Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

    Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio
    19-10-2023
    https://doi.org/10.4081/ejh.2023.3846
    1632
    PDF: 616
    HTML: 29
  • Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

    G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio
    e40
    04-12-2013
    https://doi.org/10.4081/ejh.2013.e40
    3628
    PDF: 962
    HTML: 626
  • Histochemistry in biology and medicine: a message from the citing journals

    Carlo Pellicciari
    23-12-2015
    https://doi.org/10.4081/ejh.2015.2610
    3073
    PDF: 847
    HTML: 893
  • Expressions of local renin-angiotensin system components in chondrocytes

    I. Tsukamoto, M. Akagi, S. Inoue, K. Yamagishi, S. Mori, S. Asada
    23-04-2014
    https://doi.org/10.4081/ejh.2014.2387
    2442
    PDF: 770
    HTML: 326
  • Continuous cyclic mechanical tension increases ank expression in endplate chondrocytes through the TGF-β1 and p38 pathway

    H. Xu, X. Zhang, H. Wang, Y. Zhang, Y. Shi, X. Zhang
    e28
    25-09-2013
    https://doi.org/10.4081/ejh.2013.e28
    2316
    PDF: 653
    HTML: 217
  • Histochemistry as a unique approach for investigating normal and osteoarthritic cartilage

    G. Musumeci, P. Castrogiovanni, V. Mazzone, M.A. Szychlinska, S. Castorina, C. Loreto
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2371
    3570
    PDF: 1120
    HTML: 3155
  • Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

    Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3839
    1324
    PDF: 743
    HTML: 34
  • Immunohistochemical localization of periostin in human gingiva

    T. Cobo, A. Obaya, S. Cal, L. Solares, R. Cabo, J.A. Vega, J. Cobo
    29-09-2015
    https://doi.org/10.4081/ejh.2015.2548
    2111
    PDF: 763
    HTML: 487
  • Apoptosis activation in human carious dentin. An immunohistochemical study

    C. Loreto, A. Psaila, G. Musumeci, S. Castorina, R. Leonardi
    09-07-2015
    https://doi.org/10.4081/ejh.2015.2513
    2026
    PDF: 658
    HTML: 946
  • Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study

    Giada Remoli, Chiara Rita Inguscio, Federico Boschi, Gabriele Tabaracci, Manuela Malatesta, Barbara Cisterna
    26-01-2026
    https://doi.org/10.4081/ejh.2026.4440
    362
    PDF: 176
    HTML: 6
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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