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  Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

  Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng

  17-06-2025

  https://doi.org/10.4081/ejh.2025.4218

  981

  PDF: 442

  HTML: 21
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  Reelin expression in human liver of patients with chronic hepatitis C infection

  Simone Carotti, Giuseppe Perrone, Michelina Amato, Umberto Vespasiani Gentilucci, Daniela Righi, Maria Francesconi, Claudio Pellegrini, Francesca Zalfa, Maria Zingariello, Antonio Picardi, Andrea Onetti Muda, Sergio Morini

  17-03-2017

  https://doi.org/10.4081/ejh.2017.2745

  3107

  PDF: 958

  HTML: 365
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  Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

  V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas

  e5

  08-02-2011

  https://doi.org/10.4081/ejh.2011.e5

  1395

  PDF: 763

  HTML: 3456
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  Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

  Chixian Zhang, Kai Bai, Dexu Li

  14-04-2025

  https://doi.org/10.4081/ejh.2025.4186

  1155

  PDF: 412

  HTML: 27
• 

  Expression pattern of thymosin beta 4 in the adult human liver

  S. Nemolato, P. Van Eyken, T. Cabras, F. Cau, M.U. Fanari, A. Locci, D. Fanni, C.L.P. Gerosa, I. Messana, M. Castagnola, G. Faa

  e25

  07-09-2011

  https://doi.org/10.4081/ejh.2011.e25

  1509

  PDF: 688

  HTML: 1346
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  Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

  Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

  06-08-2025

  https://doi.org/10.4081/ejh.2025.4228

  977

  PDF: 442

  HTML: 16
• 

  Bile duct ligature in young rats: A revisited animal model for biliary atresia

  Matias Garrido, Camila Escobar, Constanza Zamora, Carolina Rejas, Juan Varas, Mario Párraga, Sebastián San Martin, Sandra Montedonico

  13-09-2017

  https://doi.org/10.4081/ejh.2017.2803

  1925

  PDF: 934

  HTML: 149
• 

  Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

  G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio

  e40

  04-12-2013

  https://doi.org/10.4081/ejh.2013.e40

  3626

  PDF: 959

  HTML: 626
• 

  Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

  Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng

  02-10-2023

  https://doi.org/10.4081/ejh.2023.3839

  1318

  PDF: 743

  HTML: 34
• 

  Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

  Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra

  21-06-2022

  https://doi.org/10.4081/ejh.2022.3391

  3333

  PDF: 1850

  HTML: 47
• 

  Folic acid promotes autophagy to relieve metabolism-associated fatty liver disease by regulating NRF2

  Yu Wen, Juan Luo, Chunjing Shi, Jie Wu

  03-11-2025

  https://doi.org/10.4081/ejh.2025.4309

  691

  PDF: 470

  HTML: 24
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  Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway

  Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Han

  17-09-2024

  https://doi.org/10.4081/ejh.2024.4093

  2157

  PDF: 543

  HTML: 42
• 

  Lipids: Evergreen autofluorescent biomarkers for the liver functional profiling

  Anna Cleta Croce, Giovanni Bottiroli

  01-06-2017

  https://doi.org/10.4081/ejh.2017.2808

  1698

  PDF: 804

  HTML: 133
• 

  Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

  A.C. Croce, G. Bottiroli

  12-12-2014

  https://doi.org/10.4081/ejh.2014.2461

  13512

  PDF: 5745

  HTML: 7958
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  Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity

  Bita Moudi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Seyed-Moayed Alavian, Kamran B. Lankarani, Parisa Farrokh, Jens Randel Nyengaard

  29-01-2018

  https://doi.org/10.4081/ejh.2018.2859

  2096

  PDF: 1028

  HTML: 78
• 

  Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

  Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun

  07-04-2025

  https://doi.org/10.4081/ejh.2025.4182

  1068

  PDF: 636

  HTML: 36
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  The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

  Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang

  01-03-2023

  https://doi.org/10.4081/ejh.2023.3648

  2803

  PDF: 995

  HTML: 42
• 

  Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

  Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio

  19-10-2023

  https://doi.org/10.4081/ejh.2023.3846

  1631

  PDF: 616

  HTML: 29
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  Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

  Arvis Pauliņš, Anna Junga, Māra Pilmane

  10-02-2026

  https://doi.org/10.4081/ejh.2026.4438

  211

  PDF: 162

  HTML: 2
• 

  Contribution of intestinal smooth muscle to Crohn's disease fibrogenesis

  C. Severi, R. Sferra, A. Scirocco, A. Vetuschi, N. Pallotta, A. Pronio, R. Caronna, G. Di Rocco, E. Gaudio, E. Corazziari, P. Onori

  17-12-2014

  https://doi.org/10.4081/ejh.2014.2457

  2847

  PDF: 1112

  HTML: 434
• 

  Forever particles: histochemistry in the plasticene age

  Beatrice Camia, Andrea Casasco, Manuela Monti

  01-08-2025

  https://doi.org/10.4081/ejh.2025.4226

  833

  PDF: 430

  HTML: 41
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  Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

  V.N. Karavana, H. Gakiopoulou, E.A. Lianos

  15-04-2014

  https://doi.org/10.4081/ejh.2014.2308

  2159

  PDF: 865

  HTML: 644
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  Expression of the endocannabinoid receptors in human fascial tissue

  C. Fede, G. Albertin, L. Petrelli, M.M. Sfriso, C. Biz, R. De Caro, C. Stecco

  28-06-2016

  https://doi.org/10.4081/ejh.2016.2643

  3394

  PDF: 1749

  HTML: 2352
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  Immunolocalization of endocan during the endothelial-mesenchymal transition process

  L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez

  e13

  01-06-2011

  https://doi.org/10.4081/ejh.2011.e13

  1347

  PDF: 545

  HTML: 1336
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  Long non-coding RNA WAC antisense RNA 1 mediates hepatitis B virus replication in vitro by reinforcing miR-192-5p/ATG7-induced autophagy

  Minkai Cao, Deping Yuan, Hongxiu Jiang, Guanlun Zhou, Chao Chen, Guorong Han

  02-09-2022

  https://doi.org/10.4081/ejh.2022.3438

  1428

  PDF: 864

  HTML: 41
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  Histopathological and immunohistochemical study of the hepatic lesions experimentally induced by Entamoeba dispar

  C. A. X. Costa, K. N. O. de Brito, M. A. Gomes, M. V. Caliari

  e39

  26-08-2010

  https://doi.org/10.4081/ejh.2010.e39

  1304

  PDF: 642

  HTML: 2107

• P11 | DOMINO TRANSPLANTATION IN MNGIE: IS THE LIVER A SUITABLE GRAFT? E. Boschetti¹, I. Neri¹, S. Blando¹, C. Malagelada², L. Caporali³, R. D’Angelo⁴, R. Rinaldi⁴, S. Mongiorgi¹, V. Carelli³, R. De Giorgio⁵, L. Manzoli¹, S. Ratti¹ | ¹Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum – University of Bologna, Italy; ²Digestive System Research Unit, University Hospital Vall d’Hebron; Barcelona, Spain; ³IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; ⁴IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; ⁵Department of Translational Medicine, University of Ferrara, Ferrara, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4331

  175
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  Hormone receptor expression in human fascial tissue

  C. Fede, G. Albertin, L. Petrelli, M.M. Sfriso, C. Biz, R. De Caro, C. Stecco

  02-11-2016

  https://doi.org/10.4081/ejh.2016.2710

  3979

  PDF: 1651

  HTML: 263
• 

  Inhibition of fibrous adhesion formation in the temporomandibular joint of tenascin-C knockout mice

  Y. Shinohara, K. Okamoto, Y. Goh, N. Kiga, I. Tojyo, S. Fujita

  22-10-2014

  https://doi.org/10.4081/ejh.2014.2337

  2797

  PDF: 916

  HTML: 475

• Immunohistochemical study of macrophage migration inhibitory factor in rat liver fibrosis induced by thioacetamide

  Y Hori, S Sato, J Yamate, M Kurasaki

  317-324

  26-06-2009

  https://doi.org/10.4081/842

  924

  PDF: 1065

• P58 | VITAMIN D ATTENUATES LIVER INJURY BY REDUCING APOTOSIS, PYROPTOSIS, FERROPTOSIS AND PROMOTING REGENERATION IN TYPE 2 DIABETES S. Rzeyeva¹, N. Bayromava², T. Ozbilenler¹, A. Akdemir³, M. Anapalı Aykaç⁴, D. Aydemir⁵, F. Kaya Dagistanli¹, T. Ulutin¹, O. Uysal¹, M. Ozturk⁶ | ¹Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul, Türkiye; ²Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul, Türkiye; ³Karabuk University, Faculty of Medicine, Karabük, Türkiye; ⁴Ataturk University, Faculty of Medicine, Erzurum, Türkiye; ⁵Istanbul University, Faculty of Medicine, Istanbul, Türkiye; ⁶Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul Türkiye

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4383

  222
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  Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

  Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li

  21-01-2025

  https://doi.org/10.4081/ejh.2025.4158

  1687

  PDF: 547

  Supplementary Figure: 65

  HTML: 51

• P43 | NEW INSIGHTS IN THE ACTIVATION OF FERROPTOSIS PROCESS DURING LIVER FIBROSIS R. Mancinelli¹, S. Leone¹, A. Casini¹, R. Vaccaro¹, M. Tagliafierro¹, F.M. Bassi¹, E. Bocci¹, S. Vitale¹, A. Franchitto², L. Pannarale¹, P. Onori¹, E. Gaudio¹ | ¹Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; ²Division of Health Sciences, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4365

  193

• Simultaneous staining of cytoplasmic iron and collagen matrix in human liver biopsy specimens

  F Grizzi, G Ceva-Grimaldi, B Franceschini, M Roncalli, M Chiriva-Internati, N Dioguardi

  101-4

  30-12-2009

  https://doi.org/10.4081/1658

  651

  PDF: 548

• P62 | FFAR4/GPR120 ACTIVATION COUNTERACTS FIBROGENIC PATHWAYS IN A CHOLESTATIC LIVER INJURY MODEL S. Pompili¹, R. Sferra¹, F. Ronca¹, A. Cappariello², A. Vetuschi¹ | ¹Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy; ²Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4387

  230
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  E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

  Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei

  26-05-2025

  https://doi.org/10.4081/ejh.2025.4196

  953

  PDF: 436

  HTML: 13
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  MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

  Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo

  21-06-2022

  https://doi.org/10.4081/ejh.2022.3426

  1391

  PDF: 785

  HTML: 25
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  Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

  Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang

  07-12-2023

  https://doi.org/10.4081/ejh.2023.3816

  1101

  PDF: 657

  HTML: 28
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  Histochemistry as an irreplaceable approach for investigating functional cytology and histology

  C. Pellicciari

  e41

  19-12-2013

  https://doi.org/10.4081/ejh.2013.e41

  3325

  PDF: 840

  HTML: 408
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  Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

  Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui

  15-02-2022

  https://doi.org/10.4081/ejh.2022.3316

  1794

  PDF: 709

  HTML: 24
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  Comparison of different histological protocols for the preservation and quantification of the intestinal mucus layer in pigs

  Ilen Röhe, Friedrich Joseph Hüttner, Johanna Plendl, Barbara Drewes, Jürgen Zentek

  05-02-2018

  https://doi.org/10.4081/ejh.2018.2874

  3915

  PDF: 1677

  HTML: 250
• 

  Effect of royal jelly on experimental colitis Induced by acetic acid and alteration of mast cell distribution in the colon of rats

  T. Karaca, F. Bayiroglu, M.U. Yoruk, S. Kaya, S. Uslu, B. Comba, L. Mis

  e35

  21-10-2010

  https://doi.org/10.4081/ejh.2010.e35

  3529

  PDF: 823

  HTML: 5293
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  miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

  Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li

  22-09-2025

  https://doi.org/10.4081/ejh.2025.4239

  395

  PDF: 267

  Supplementary: 31

  HTML: 16
• 

  Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

  C. Pellicciari

  30-12-2014

  https://doi.org/10.4081/ejh.2014.2474

  2244

  PDF: 658

  HTML: 807
• 

  Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation

  Hongkai Xiao, Jinghu Liu, Qinhong Cai, Siyu Liang, Zhitao Hu, Xiaochao Chen

  13-10-2025

  https://doi.org/10.4081/ejh.2025.4254

  471

  PDF: 324

  HTML: 37

• Atorvastatin reduces calcification in valve interstitial cells via the NF-κB signalling pathway by promoting Atg5-mediated autophagy

  Menghui Chen, Su Liu

  12-04-2024

  https://doi.org/10.4081/ejh.2024.3983

  1223

  PDF: 528

  HTML: 17
• 

  Targeting EphA2 suppresses the proliferation, migration and invasion of endometriosis via the AMPK signaling pathway

  Chaoyi Yang, Shujun Wang, Mengru Li, Xiangli Pang, Aili Tan

  17-06-2025

  https://doi.org/10.4081/ejh.2025.4168

  477

  PDF: 279

  HTML: 12
• 

  Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

  Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu

  17-11-2025

  https://doi.org/10.4081/ejh.2025.4426

  658

  PDF: 389

  HTML: 14
• 

  Perinatal Stem Cells - Biology, Manufacturing and Translational Medicine

  Manuela Monti

  29-06-2021

  https://doi.org/10.4081/ejh.2021.3291

  1703

  PDF: 435

  HTML: 22
• 

  Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

  Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai

  14-10-2022

  https://doi.org/10.4081/ejh.2022.3510

  1230

  PDF: 658

  HTML: 33

• P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY S. Blando¹, E. Boschetti¹, I. Neri¹, L. Caporali², C. Fiorini², D. Ormanbekova², C. Malagelada³, I. Rusciano¹, V. Carelli², R. De Giorgio⁴, L. Manzoli¹, S. Ratti¹ | ¹Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Italy; ²IRCCS Institute of Neurological Sciences of Bologna, Neurogenetics Program, Bologna, Italy; ³Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; ⁴Department of Translational Medicine, University of Ferrara, Ferrara, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4327

  146
• 

  Next-generation nutritional biomarkers to guide better health care

  CarloAlberto Redi

  19-04-2016

  https://doi.org/10.4081/ejh.2016.2666

  1320

  PDF: 696

  HTML: 105

• Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

  Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang

  29-04-2024

  https://doi.org/10.4081/ejh.2024.4019

  1758

  PDF: 544

  HTML: 17
• 

  Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

  Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

  26-01-2026

  https://doi.org/10.4081/ejh.2026.4422

  524

  PDF: 292

  Supplementary: 17

  Original gels: 20

  HTML: 8

• IMMUNOLOGICAL MECHANISMS IN REGENERATIVE MEDICINE: A LESSON FROM THE HUMAN PLACENTA O. Parolini^1,2 | ¹Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy; ²Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4266

  295