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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Mammaglobin, GATA-binding protein 3 (GATA3), and epithelial growth factor receptor (EGFR) expression in different breast cancer subtypes and their clinical significance

    Xin Kong, Qi Wang, Jie Li, Ming Li, Fusheng Deng, Chuanying Li
    07-04-2022
    https://doi.org/10.4081/ejh.2022.3315
    1566
    PDF: 794
    Supplementary: 149
    HTML: 17
  • Striatal topographical organization: Bridging the gap between molecules, connectivity and behavior

    Gianpaolo Antonio Basile, Salvatore Bertino, Alessia Bramanti, Rosella Ciurleo, Giuseppe Pio Anastasi, Demetrio Milardi, Alberto Cacciola
    13-10-2021
    https://doi.org/10.4081/ejh.2021.3284
    2686
    PDF: 1272
    HTML: 27
  • Sporadic Creutzfeldt-Jakob disease: Real-Time Quaking Induced Conversion (RT-QuIC) assay represents a major diagnostic advance

    Federico Angelo Cazzaniga, Edoardo Bistaffa, Chiara Maria Giulia De Luca, Giuseppe Bufano, Antonio Indaco, Giorgio Giaccone, Fabio Moda
    15-10-2021
    https://doi.org/10.4081/ejh.2021.3298
    2729
    PDF: 1104
    HTML: 35
  • OTX1 and OTX2 as possible molecular markers of sinonasal carcinomas and olfactory neuroblastomas

    Cristina Pirrone, Anna M. Chiaravalli, Alessandro Marando, Andrea Conti, Alessia Rainero, Andrea Pistochini, Francesco Lo Curto, Francesco Pasquali, Paolo Castelnuovo, Carlo Capella, Giovanni Porta
    09-02-2017
    https://doi.org/10.4081/ejh.2017.2730
    2506
    PDF: 1131
    HTML: 354
  • Human equilibrative nucleoside transporter 1 and carcinoma of the ampulla of Vater: expression differences in tumour histotypes

    G. Perrone, S. Morini, D. Santini, C. Rabitti, B. Vincenzi, R. Alloni, A. Antinori, P. Magistrelli, R. Lai, C. Cass, J. R. Mackey, R. Coppola, G. Tonini, A. Onetti Muda
    e38
    13-09-2010
    https://doi.org/10.4081/ejh.2010.e38
    1450
    PDF: 683
    HTML: 1737
  • dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas

    Y. Zhang, W.Y. Ye, J.Q. Wang, S.J. Wang, P. Ji, G.Y. Zhou, G.P. Zhao, H.L. Ge, Y. Wang
    e29
    25-09-2013
    https://doi.org/10.4081/ejh.2013.e29
    2986
    PDF: 808
    HTML: 419
  • Novel understanding on genetic mechanisms of enteric neuropathies leading to severe gut dysmotility

    Francesca Bianco, Giulia Lattanzio, Luca Lorenzini, Chiara Diquigiovanni, Maurizio Mazzoni, Paolo Clavenzani, Laura Calzà, Luciana Giardino, Catia Sternini, Elena Bonora, Roberto De Giorgio
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3289
    2419
    PDF: 1325
    HTML: 54
  • Mast cells in meningiomas

    Antonio D'Amati, Roberto Tamma, Tiziana Annese, Anna Rizzi, Domenico Ribatti
    18-04-2024
    https://doi.org/10.4081/ejh.2024.3973
    1444
    PDF: 430
    HTML: 25
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2686
    PDF: 998
    HTML: 153
  • A single simple procedure for dewaxing, hydration and heat-induced epitope retrieval (HIER) for immunohistochemistry in formalin fixed paraffin-embedded tissue

    I.M.S. Paulsen, H. Dimke, S. Frische
    03-11-2015
    https://doi.org/10.4081/ejh.2015.2532
    3443
    PDF: 1735
    HTML: 804
  • Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

    C. Pellicciari
    e51
    16-12-2010
    https://doi.org/10.4081/ejh.2010.e51
    1480
    PDF: 727
    HTML: 3887
  • Pleural mesothelioma from fluoro-edenite exposure: PACAP and PAC1 receptor. A preliminary report

    Claudia Lombardo, Grazia Maugeri, Agata Grazia D'Amico, Giuseppe Broggi, Rosario Caltabiano, Veronica Filetti, Serena Matera, Velia D'Agata, Carla Loreto
    02-05-2024
    https://doi.org/10.4081/ejh.2024.3994
    1505
    PDF: 459
    HTML: 30
  • alpha2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade

    Michael W.L. Quirino, Amanda P.B. Albuquerque, Maria F.D. de Souza, Antônio F. da Silva Filho, Mário R. Martins, Maira G. da Rocha Pitta, Michelly C. Pereira, Moacyr J.B. de Melo Rêgo
    29-09-2022
    https://doi.org/10.4081/ejh.2022.3330
    1366
    PDF: 714
    Supplementary: 125
    HTML: 30
  • SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

    Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang
    18-05-2026
    https://doi.org/10.4081/ejh.2026.4544
    97
    PDF: 78
    Supplementary: 12
    HTML: 2
  • Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

    Jiapei Lv, Wang Yanting, Shan Wei
    08-11-2023
    https://doi.org/10.4081/ejh.2023.3867
    1990
    PDF: 964
    HTML: 46
  • Localization of peripheral autonomic neurons innervating the boar urinary bladder trigone and neurochemical features of the sympathetic component

    L. Ragionieri, M. Botti, F. Gazza, C. Sorteni, R. Chiocchetti, P. Clavenzani, L. Bo, R. Panu
    e16
    06-05-2013
    https://doi.org/10.4081/ejh.2013.e16
    2460
    PDF: 1166
    HTML: 1039
  • Expression of parafibromin in major renal cell tumors

    C. Cui, P. Lal, S. Master, Y. Ma, T. Baradet, Z. Bing
    e39
    23-10-2012
    https://doi.org/10.4081/ejh.2012.e39
    1467
    PDF: 644
    HTML: 221
  • Developmental expression of inositol 1, 4, 5-trisphosphate receptor in the post-natal rat cochlea

    W.J. Liu, J. Yang
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2486
    2244
    PDF: 780
    HTML: 1033
  • Cancer stem cell markers ALDH1 and CD44+/CD24- phenotype and their prognosis impact in invasive ductal carcinoma

    Iris Rabinovich, Ana Paula Martins Sebastião, Rubens Silveira Lima, Cícero de Andrade Urban, Eduardo Schunemann Junior, Karina Furlan Anselmi, Selene Elifio-Esposito, Lucia de Noronha, Andréa Novais Moreno-Amaral
    03-09-2018
    https://doi.org/10.4081/ejh.2018.2943
    2915
    PDF: 1075
    HTML: 38
  • SerpinB3 administration protects liver against ischemia-reperfusion injury

    Cristian Turato, Mariapia Vairetti, Marta Cagna, Alessandra Biasiolo, Andrea Ferrigno, Santina Quarta, Mariagrazia Ruvoletto, Silvia De Siervi, Patrizia Pontisso, Laura Giuseppina Di Pasqua
    28-10-2022
    https://doi.org/10.4081/ejh.2022.3561
    1295
    PDF: 747
    HTML: 34
  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    301
    PDF: 223
    Raw data: 36
    HTML: 14
  • Thymosin beta 4 expression in normal skin, colon mucosa and in tumor infiltrating mast cells

    S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, M. Fraschini, B. Manconi, I. Messana, M. Castagnola, G. Faa
    e3
    16-02-2010
    https://doi.org/10.4081/ejh.2010.e3
    1030
    PDF: 547
    HTML: 1425
  • NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

    Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou
    30-06-2025
    https://doi.org/10.4081/ejh.2025.4221
    807
    PDF: 424
    HTML: 16
  • Hormone receptor expression in human fascial tissue

    C. Fede, G. Albertin, L. Petrelli, M.M. Sfriso, C. Biz, R. De Caro, C. Stecco
    02-11-2016
    https://doi.org/10.4081/ejh.2016.2710
    4072
    PDF: 1695
    HTML: 263
  • Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

    Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno
    15-03-2018
    https://doi.org/10.4081/ejh.2018.2841
    14475
    PDF: 7082
    HTML: 465
  • P22 | EXPLORING THE UNEXPECTED DUAL ROLE OF GARLIC DERIVATIVES IN REGULATING INVASIVENESS IN BREAST CANCER SUBTYPES M. Dell’Aira1, S. Grassilli2, M. Pierantoni1, V. Bertagnolo1, F. Brugnoli1 | 1Department of Translational Medicine, University of Ferrara, Ferrara, Italy; 2Department of Environmental Sciences and Prevention and LTTA Centre, University of Ferrara, Ferrara, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4342
    218
  • Alarin regulates RyR2 and SERCA2 to improve cardiac function in heart failure with preserved ejection fraction

    Jinshuang Li, Dawei Xu, Ce Shi, Chunqi Cheng, Ziheng Xu, Xingjuan Gao, Yong Cheng
    28-10-2024
    https://doi.org/10.4081/ejh.2024.4122
    1440
    PDF: 550
    HTML: 15
  • The matrix stiffness is increased in the eutopic endometrium of adenomyosis patients: a study based on atomic force microscopy and histochemistry

    Xiaowen Wang, Wenbin Cai, Ting Liang, Hui Li, Yingjie Gu, Xiaojiao Wei, Hong Zhang, Xiaojun Yang
    04-12-2024
    https://doi.org/10.4081/ejh.2024.4131
    1892
    PDF: 481
    HTML: 55
  • Three-dimensional scaffold-free fusion culture: the way to enhance chondrogenesis of in vitro propagated human articular chondrocytes

    M. Lehmann, F. Martin, K. Mannigel, K. Kaltschmidt, U. Sack, U. Anderer
    e31
    05-11-2013
    https://doi.org/10.4081/ejh.2013.e31
    4819
    PDF: 1059
    HTML: 965
  • miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

    Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi
    23-09-2025
    https://doi.org/10.4081/ejh.2025.4238
    410
    PDF: 309
    HTML: 11
  • Characterization of cytoskeleton features and maturation status of cultured human iPSC-derived cardiomyocytes

    Christian Zuppinger, George Gibbons, Priyanka Dutta-Passecker, Adrian Segiser, Henriette Most, Thomas M. Suter
    21-06-2017
    https://doi.org/10.4081/ejh.2017.2763
    4997
    PDF: 2120
    HTML: 288
  • Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

    Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li
    17-05-2023
    https://doi.org/10.4081/ejh.2023.3612
    1350
    PDF: 907
    Supplementary: 92
    HTML: 21
  • Angiotensin II: immunohistochemical study in Sardinian pterygium

    P. Demurtas, M. Corrias, I. Zucca, C. Maxia, F. Piras, P. Sirigu, M.T. Perra
    28-07-2014
    https://doi.org/10.4081/ejh.2014.2426
    2140
    PDF: 750
    HTML: 362
  • Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

    V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas
    e5
    08-02-2011
    https://doi.org/10.4081/ejh.2011.e5
    1418
    PDF: 782
    HTML: 3459
  • ON THE WAY TO A NEW MODEL OF NEURODEGENERATION? FIRST EVIDENCE OF THE EXPRESSION OF GATA1 IN THE BRAIN: CORRELATIONS WITH AGING, MITOCHONDRIAL DAMAGE AND SYNUCLEINOPATHY C. Caturano1, F. E. Bellomi1, F. Arciprete1, V. Velardi1, L. La Barbera2, M. Falchi3, M. Bacioglu4, R. Mancinelli5, M. D’Amelio2, M. Spillantini4, M. Zingariello1, G. Vivacqua1,6 | 1Laboratory of Microscopic and Ultrastructural Anatomy, Campus Biomedico University of Rome, Italy; 2Laboratory of Molecular Neuroscience - Campus Biomedico University of Rome, Italy; 3National Centre for HIV/AIDS Research, Istituto Superior di Sanità, Rome, Italy; 4Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK; 5Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy; 6Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4315
    258
  • The multifaceted role of podoplanin expression in hepatocellular carcinoma

    Andreea Cioca, Amalia R. Ceausu, Irina Marin, Marius Raica, Anca M. Cimpean
    13-02-2017
    https://doi.org/10.4081/ejh.2017.2707
    2503
    PDF: 846
    HTML: 318
  • Subcutaneous adipose tissue classification

    A. Sbarbati, D. Accorsi, D. Benati, L. Marchetti, G. Orsini, G. Rigotti, P. Panettiere
    e48
    25-11-2010
    https://doi.org/10.4081/ejh.2010.e48
    3760
    PDF: 1345
    HTML: 2637
  • P64 | EX VIVO EXTRACTION OF GLIOMA SECRETOME: A NOVEL MICROENVIRONMENT-BASED PROTOCOL FOR METABOLIC AND MOLECULAR PROFILING I. Neri1, M.V. Marvi1, V. Righi2, V. Papa3, E. Boschetti1, S. Blando1, E. Franceschi4, M. Zoli4, D. Mazzatenta4, N. Neri4, A. Vignaroli4, L. Cocco1, L. Manzoli1, S. Ratti1 | 1Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Department of Life Quality Sciences, University of Bologna, Bologna, Italy; 3IRCCS St. Orsola, Bologna, Italy; 4IRCCS Institute of Neurological Sciences of Bologna, Bologna, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4389
    293
  • Immunohistochemical expression and clinicopathological assessment of PD-1, PD-L1, NY-ESO-1, and MAGE-A4 expression in highly aggressive soft tissue sarcomas

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi
    22-04-2022
    https://doi.org/10.4081/ejh.2022.3393
    1282
    PDF: 709
    HTML: 24
  • Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour

    W. Meyer, M. Liumsiricharoen, A. Suprasert, L.G. Fleischer, M. Hewicker-Trautwein
    e27
    16-09-2013
    https://doi.org/10.4081/ejh.2013.e27
    3453
    PDF: 1148
    HTML: 514
  • KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion

    A. Porzionato, G. Fenu, M. Rucinski, V. Macchi, A. Montella, L. K. Malendowicz, R. De Caro
    e14
    04-05-2011
    https://doi.org/10.4081/ejh.2011.e14
    1253
    PDF: 539
    HTML: 1055
  • The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesions

    L. Pilloni, P. Bianco, E. DiFelice, S. Cabras, M.E. Castellanos, L. Atzori, C. Ferreli, P. Mulas, S. Nemolato, G. Faa
    e20
    07-06-2011
    https://doi.org/10.4081/ejh.2011.e20
    1304
    PDF: 693
    HTML: 9925
  • The role of galanin in the progression and prognosis of colorectal cancer: the unfinished story

    Zbigniew Kmiec, Jacek Kieżun, Bartlomiej E. Krazinski, Przemyslaw Kwiatkowski, Janusz Godlewski
    06-03-2024
    https://doi.org/10.4081/ejh.2024.3990
    1454
    PDF: 440
    HTML: 14
  • Seasonal expression of androgen receptor, aromatase, and estrogen receptor alpha and beta in the testis of the wild ground squirrel (Citellus dauricus Brandt)

    Q. Li, F. Zhang, S. Zhang, X. Sheng, X. Han, Q. Weng, Z. Yuan
    17-02-2015
    https://doi.org/10.4081/ejh.2015.2456
    2432
    PDF: 844
    HTML: 708
  • Swertianolin ameliorates immune dysfunction in sepsis via blocking the immunosuppressive function of myeloid-derived suppressor cells

    Zongfang Ren, Haoren Tang, Linjun Wan, Xing Liu, Ning Tang, Lingling Wang, Zhenhui Guo
    01-09-2021
    https://doi.org/10.4081/ejh.2021.3292
    1451
    PDF: 941
    HTML: 36
  • Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

    J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2256
    3678
    PDF: 908
    HTML: 508
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
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Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
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European Journal of Histochemistry

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