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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
Impact Factor 2025
3.7
CiteScore 2025
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1.9
Impact Factor 2025
3.7
CiteScore 2025
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  • Immunofluorescent localization of ubiquitin and proteasomes in nucleolar vacuoles of soybean root meristematic cells

    D. Stępiński
    e13
    30-05-2012
    https://doi.org/10.4081/ejh.2012.13
    1196
    PDF: 478
    HTML: 1793
  • Bradykinin and noradrenaline preconditioning influences level of antioxidant enzymes SOD, CuZn-SOD, Mn-SOD and catalase in the white matter of spinal cord in rabbits after ischemia/reperfusion

    Marianna Danková, Iveta Domoráková, Zuzana Fagová, Milan Stebnický, Alexandra Kunová, Eva Mechírová
    18-10-2019
    https://doi.org/10.4081/ejh.2019.3045
    1682
    PDF: 736
    HTML: 12
  • Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability

    Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3352
    1802
    PDF: 795
    HTML: 34
  • Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer

    J. Ning, J. Zhang, W. Liu, Y. Lang, Y. Xue, S. Xu
    e46
    30-11-2012
    https://doi.org/10.4081/ejh.2012.e46
    2583
    PDF: 785
    HTML: 513
  • Morphology, clearing efficacy, and mTOR dependency of the organelle autophagoproteasome

    Fiona Limanaqi, Francesca Biagioni, Alessandra Salvetti, Stefano Puglisi-Allegra, Paola Lenzi, Francesco Fornai
    01-06-2021
    https://doi.org/10.4081/ejh.2021.3220
    1451
    PDF: 536
    HTML: 19
  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    541
    PDF: 331
    Raw data: 42
    HTML: 17
  • Tripartite motif-containing protein 6 facilitates growth and migration of breast cancer through degradation of STUB1

    Chuanchao Wei, Jiayue Wu, Weiyan Liu, Jingfeng Lu, Hongchang Li, Benjun Hai
    10-03-2021
    https://doi.org/10.4081/ejh.2021.3214
    1803
    PDF: 872
    Supplementary: 168
    HTML: 19
  • Deubiquitinase USP14 is upregulated in Crohn's disease and inhibits the NOD2 pathway mediated inflammatory response in vitro

    Mengling Li, Yan Zhao, Jiayi Zhang, Wang Jiang, Siyuan Peng, Jinyue Hu, Yueming Shen
    09-09-2024
    https://doi.org/10.4081/ejh.2024.4101
    1348
    PDF: 450
    HTML: 17
  • Super-resolution study of PIAS SUMO E3-ligases in hippocampal and cortical neurons

    Andrea Conz, Clara Alice Musi, Luca Russo, Tiziana Borsello, Luca Colnaghi
    11-08-2021
    https://doi.org/10.4081/ejh.2021.3241
    1713
    PDF: 744
    HTML: 23
  • The clinical significance of UBE2C gene in progression of renal cell carcinoma

    Zhiping Chen, Lanfeng Wang
    29-03-2021
    https://doi.org/10.4081/ejh.2021.3196
    1945
    PDF: 906
    HTML: 31
  • PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage

    J. Suchánková, S. Legartová, P. Sehnalová, S. Kozubek, S. Valente, D. Labella, A. Mai, C. Eckerich, F.O. Fackelmayer, D.V. Sorokin, E. Bartova
    02-05-2014
    https://doi.org/10.4081/ejh.2014.2389
    3137
    PDF: 766
    Supplementary: 322
    HTML: 814
  • Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

    Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li
    22-07-2024
    https://doi.org/10.4081/ejh.2024.4048
    2434
    PDF: 1366
    HTML: 22
  • Visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis

    Hai-rong Fu, Xiao-shan Li, Yong-hui Zhang, Bin-bin Feng, Lian-hong Pan
    07-09-2020
    https://doi.org/10.4081/ejh.2020.3131
    1324
    PDF: 947
    HTML: 15
  • IMPAIRMENT OF HERP E3 LIGASE ACTIVITY BY MUTANT POLYGLUTAMINE PROTEINS: A NOVEL MECHANISM IN POLYGLUTAMINE DISEASE NEUROPATHOLOGY T. Peng, B. Zhang, M. Yang, H. Li | Department of Histology and Embryology, School of Basic Medical Sciences, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4316
    280
  • P19 | IDENTIFICATION OF MIR-129-5P AS A COMMON REGULATOR OF E3 UBIQUITIN LIGASES WITH A POTENTIAL ROLE IN GLIOBLASTOMA PROGRESSION N. Martella1, A.B. Díaz Méndez2, G. Regazzo2, G.F. Bufalieri3, A. Frati4, A. Arcella4, L. Di Marcotullio3, M.G. Rizzo2, S. Di Bartolomeo1 | 1Dept. of Biosciences and Territory, University of Molise, Italy; 2Dept. of Research, Advanced Diagnostics and Technological Innovation, Translational Oncology Research Unit, IRCCS -Regina Elena National Cancer Institute, Rome, Italy; 3Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy; 4IRCCS Neuromed, Pozzilli (IS), Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4715
    48
    PDF: 17
  • Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

    A.M. Schläfli, S. Berezowska, O. Adams, R. Langer, M.P. Tschan
    05-05-2015
    https://doi.org/10.4081/ejh.2015.2481
    8780
    PDF: 3319
    HTML: 2170
  • Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

    Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3412
    2569
    PDF: 1437
    HTML: 33
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3420
    PDF: 912
    HTML: 409
  • The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model

    Roman M. Kassa, Roberta Bonafede, Federico Boschi, Manuela Malatesta, Raffaella Mariotti
    17-05-2018
    https://doi.org/10.4081/ejh.2018.2904
    2138
    PDF: 744
    HTML: 32
  • SUMOYLATION AS AN EARLY ADAPTIVE MECHANISM IN THE PROTEOMIC RESPONSE OF HUMAN GERM CELLS TO SIMULATED MICROGRAVITY A. Di Pauli1, G. Ricci2, M. Crescenzi3, M. A. Mariggiò4, C. Morabito4, L. Gesualdi1, M. Berardini1, F. Ferranti5, M. Signore6, A. Catizone1 | 1Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, Section of Histology and Embryology, «Sapienza» University, Rome, Italy; 2Department of Experimental Medicine, University «Luigi Vanvitelli», Naples, Italy; 3Core Facilities, Italian National Institute of Health, Rome, Italy; 4Department of Neuroscience, Imaging and Clinical Sciences CAST, «G. d’Annunzio» University, Chieti, Italy; 5Human Spaceflight and Scientific Research Unit, Italian Space Agency, Rome, Italy; 6RPPA unit, Proteomics, Italian National Institute of Health, Rome, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4296
    203
  • High glucose inhibits neural differentiation by excessive autophagy via peroxisome proliferator-activated receptor gamma

    Yin Pan, Di Qiu, Shu Chen, Xiaoxue Han, Ruiman Li
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3691
    1355
    PDF: 913
    HTML: 24
  • Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases

    G. Natale, E. Pompili, F. Biagioni, S. Paparelli, P. Lenzi, F. Fornai
    e5
    07-03-2013
    https://doi.org/10.4081/ejh.2013.e5
    3366
    PDF: 808
    HTML: 209
  • High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

    Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari
    16-12-2024
    https://doi.org/10.4081/ejh.2024.4145
    1426
    PDF: 588
    HTML: 9
  • Autophagic processes increase during senescence in cultured sheep neurons and astrocytes

    Vittorio Farina, Gianluca Lepore, Francesca Biagi, Marcella Carcupino, Marco Zedda
    03-04-2018
    https://doi.org/10.4081/ejh.2018.2891
    2467
    PDF: 699
    HTML: 25
  • On the future contents of a small journal of histochemistry

    C. Pellicciari
    e51
    10-12-2012
    https://doi.org/10.4081/ejh.2012.e51
    2578
    PDF: 989
    HTML: 942
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    342
    PDF: 487
    Supplementary: 39
    HTML: 5
  • miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

    Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3237
    1737
    PDF: 590
    HTML: 27
  • Deletion of osteopontin in non-small cell lung cancer cells affects bone metabolism by regulating miR-34c/Notch1 axis: a clue to bone metastasis

    Jing Guo, Chang-Yong Tong, Jian-Guang Shi, Xin-Jian Li, Xue-Qin Chen
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3631
    1427
    PDF: 770
    HTML: 28
  • Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study

    A. Santoro, G. Pannone, M.E. Errico, D. Bifano, G. Lastilla, P. Bufo, C. Loreto, V. Donofrio
    e25
    02-07-2012
    https://doi.org/10.4081/ejh.2012.e25
    1583
    PDF: 656
    HTML: 5417
  • Galunisertib enhances chimeric antigen receptor-modified T cell function

    Zhixiong Wang, Qian Liu, Na Risu, Jiayu Fu, Yan Zou, Jiaxing Tang, Long Li, Hui Liu, Guomin Zhou, Xuekai Zhu
    19-06-2020
    https://doi.org/10.4081/ejh.2020.3122
    2100
    PDF: 1115
    Supplementary: 173
    HTML: 20
  • Successful triple immunoenzymatic method employing primary antibodies from same species and same immunoglobulin subclass

    T. A. Osman, G. Øijordsbakken, D. E. Costea, A. C. Johannessen
    e22
    16-09-2013
    https://doi.org/10.4081/ejh.2013.e22
    3254
    PDF: 902
    HTML: 2122
  • Expression of the HPV18/E6 oncoprotein induces DNA damage

    Elva I. Cortés Gutiérrez, Catalina Garcí­a-Vielma, Adriana Aguilar-Lemarroy, Veronica Vallejo-Ruí­z, Patricia Piña-Sánchez, Pablo Zapata-Benavides, Jaime Gosalvez
    15-06-2017
    https://doi.org/10.4081/ejh.2017.2773
    1990
    PDF: 819
    HTML: 213
  • LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

    Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu
    31-05-2023
    https://doi.org/10.4081/ejh.2023.3535
    1249
    PDF: 679
    HTML: 37
  • Immunological detection of m- and µ-calpains in the skeletal muscle of Marchigiana cattle

    E. Varricchio, M.G. Russolillo, L. Maruccio, S. Velotto, G. Campanile, M. Paolucci, F. Russo
    e2
    14-01-2013
    https://doi.org/10.4081/ejh.2013.e2
    8117
    PDF: 762
    HTML: 535
  • P22 | COORDINATION OF MITOPHAGY AND EMT PROGRAMS IN BRAIN TUMOR CELL PLASTICITY Ilaria Montano1, Valeria Nanni1, Manuela Giansanti2, Veronica Marabitti1|3, Francesca Nazio1 | 1Department of Biology, University of Rome Tor Vergata, Rome, Italy; 2Innate Lymphoid Cells Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy; 3Dipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica del Sacro Cuore, Rome, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4718
    38
    PDF: 16
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    3093
    PDF: 1187
    Supplementary: 394
    HTML: 1018
  • Apoptosis induced by proteasome inhibition in human myoblast cultures

    J Sassone, A Ciammola, C Tiloca, M Glionna, G Meola, E Mancinelli, V Silani
    109-118
    30-06-2009
    https://doi.org/10.4081/981
    529
    PDF: 461
  • Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy

    Fenqiang Qi, Yuxin Deng, Wei Huang, Yanli Cai, Kelin Hong, Shui Xiang
    15-10-2024
    https://doi.org/10.4081/ejh.2024.4104
    2486
    PDF: 623
    HTML: 7
  • Phosphorylation mutation impairs the promoting effect of spastin on neurite outgrowth without affecting its microtubule severing ability

    Yunlong Zhang, Xin He, Jianyu Zou, Jie Yang, Ao Ma, Minghui Tan
    12-01-2023
    https://doi.org/10.4081/ejh.2023.3594
    1507
    PDF: 801
    HTML: 35
  • Comparison between Lipofectamine RNAiMAX and GenMute transfection agents in two cellular models of human hepatoma

    Clarissa Berardo, Veronica Siciliano, Laura G. Di Pasqua, Plinio Richelmi, Mariapia Vairetti, Andrea Ferrigno
    06-08-2019
    https://doi.org/10.4081/ejh.2019.3048
    3147
    PDF: 1946
    HTML: 36
  • SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

    Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang
    18-05-2026
    https://doi.org/10.4081/ejh.2026.4544
    194
    PDF: 169
    Supplementary: 23
    HTML: 7
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2429
    PDF: 698
    HTML: 823
  • VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

    Meiying Zhang, Min Zhou, Xia Cai, Yan Zhou, Xueling Jiang, Yan Luo, Yue Hu, Rong Qiu, Yanrong Wu, Yuejin Zhang, Yan Xiong
    27-10-2022
    https://doi.org/10.4081/ejh.2022.3522
    2362
    PDF: 1049
    HTML: 46
  • Optimization of the autophagy measurement in a human cell line and primary cells by flow cytometry

    Tonino Alonzi, Elisa Petruccioli, Valentina Vanini, Gian Maria Fimia, Delia Goletti
    26-06-2019
    https://doi.org/10.4081/ejh.2019.3044
    2148
    PDF: 1242
    Supplementary: 197
    HTML: 32
  • AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in autophagy-induced astrocytoma cells

    L. Fassina, G. Magenes, A. Inzaghi, S. Palumbo, G. Allavena, C. Miracco, L. Pirtoli, M. Biggiogera, S. Comincini
    e44
    11-10-2012
    https://doi.org/10.4081/ejh.2012.e44
    2074
    PDF: 1003
    Supplementary Figures: 314
    Supplementary Table: 230
    HTML: 505
  • MicroRNA-29b-3p promotes 5-fluorouracil resistance via suppressing TRAF5-mediated necroptosis in human colorectal cancer

    Shuimei Wu, Yun Zhou, Ping Liu, Hui Zhang, Wanliang Wang, Yuan Fang, Xiang Shen
    22-06-2021
    https://doi.org/10.4081/ejh.2021.3247
    2112
    PDF: 1030
    Supplementary: 205
    HTML: 21
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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