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MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices
2502PDF: 1215MIAQuant user Manual: 267MIAQuant source code: 343HTML: 77 -
EXPLORING THE CYTOTOXIC AND APOPTOTIC ACTIVITIES OF PRUNUS SPINOSA ECOTYPE EXTRACT TRIGNO ON 3D AND 2D MODELS OF HUMAN CANCER CELLS A. Di Netta1, A. Di Pauli2, R. Vona3, C. Cittadini3, S. Meschini1, M. Condello1 | 1 National Center for Drug Research and Evaluation, National Institute of Health, Rome, Italy; 2 Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, «Sapienza» University of Rome, Rome, Italy: 3 National Center for Gender-Specific Medicine, National Institute of Health, Rome, Italy
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Decreased expression of Met during differentiation in rat lung
1675PDF: 781Supplementary: 317HTML: 281 -
REDUCING PACLITAXEL-INDUCED PERIPHERAL NEUROTOXICITY VIA LIPOSOMAL DRUG TARGETING Molteni L1, Persico A2, Kravicz M3, Antoniou A4, Peqini K4, Mantecca P2, Nicolini G1, Pellegrino S4, Re F3 and Bragato C2 | 1Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; 2POLARIS Research Center, Dept. of Earth and Environmental Sciences, University of Milano-Bicocca, Milan, Italy; 3School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; 4Department of Pharmaceutical Sciences, University of Milan, Milan, Italy
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34 | CYTOTOXIC EFFECTS OF SICILIAN GRAPE SEED OILS ON CANCER CELLS D. Ganci1, G. Abruscato2, R. Chiarelli1, M. Mauro1|2, V. Arizza1|2, M. Vazzana1|2, C. Luparello1|2 | 1Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2NFBC, National Biodiversity Future Center, Palermo, Italy
76PDF: 12 -
22 | TRANSCRIPTIONAL AND POST-TRANSLATIONAL NETWORKS COORDINATE SELECTIVE AUTOPHAGY TO MAINTAIN ORGANELLE HOMEOSTASIS K. Hartfelt1, M. Petraroia2, T. Persichini2, M. Colasanti2, C. Di Malta3, F. Cecconi4, V. Cianfanelli2 | 1Unit of Cell Stress and Survival, Danish Cancer Institute, Copenhagen, Denmark; 2Dept. of Science, University Roma TRE, Rome, Italy; 3Telethon Institute of Genetics and Medicine, Naples, Italy; 4Dept. of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics Research, Catholic University of the Sacred Heart, Rome, Italy
124PDF: 32 -
PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage
3126PDF: 765Supplementary: 321HTML: 814 -
P81 | AN IN VITRO CYTOTOXIC, PROAPOPTOTIC AND ANTITUMOR ACTIVITY ASSESSMENT FOR CERAMIDASE INHIBITORS ON HUMAN LARYNGEAL CANCER CELLS C. Vejselova Sezer1, M. Cengiz2, B. Gür3, R. Dündar4, C. Cingi5, H.M. Kutlu6 | 1Department of Biology, Kutahya Dumlupinar University, Kutahya, Türkiye; 2Department of Mathematics and Physical Sciences Education, Siirt University, Siirt, Türkiye; 3Department of Biochemistry, Iğdır University, Iğdır, Türkiye; 4Department of Otorhinolaryngology, Acibadem Eskişehir Hospital, Eskişehir, Türkiye; 5Department of Otorhinolaryngology, Eskişehir Osmangazi University, Eskişehir, Türkiye; 6Department of Biology, Eskişehir Technical University, Eskişehir, Türkiye
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TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti1, M. C. Gagliani2, G. Bellese2, M. Crippa3, A. Abbona4, M. Paccagnella4, P. Arnaldi5, M. C. Merlano6, O. Garrone7, A.M. Porcelli8, M. Matteoli1, P. Falletta9, P. Castagnola10, K. Cortese2 | 1IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; 2DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; 3Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; 4Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; 5IRCCS Ospedale Policlinico San Martino, Genova, Italy; 6Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; 7Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 8FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; 9Vita-Salute San Raffaele University, Milan, Italy; 10IRCCS Ospedale Policlinico San Martino, Genova, Italy
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Stem Cells and Therapy: Emerging Approaches
2113PDF: 388HTML: 10 -
THE USE OF BIOMIMETIC 2D AND 3D UROTHELIAL IN VITRO MODELS WITH MOLECULAR, MORPHOLOGICAL AND FUNCTIONAL CHARACTERISTICS OF NORMAL AND CANCEROUS BLADDER TISSUE AS AN ALTERNATIVE METHOD IN PRECLINICAL STUDIES M.E. Kreft1, L. Tratnjek1, A. Janev1, N. Resnik1, U. Cerkvenik1, U. D. Jerman1, G. Markovič1, T.Ž. Ramuta1, T. Višnjar1, Ž. Sardoč1, A.Punčuh1, S. Kralj2, M. Čemažar3, P. Veranič1 |1Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; 2Department for Materials Synthesis, Jožef Stefan Institute, Ljubljana, Slovenia; 3Institute of Oncology Ljubljana, Ljubljana, Slovenia
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PURKINJE CELL INTEGRITY IS PRESERVED BY EXERCISE IN PARANEOPLASTIC CEREBELLAR DEGENERATION: EVIDENCE FROM A CANCER CACHEXIA MOUSE MODEL Zummo FP1, Saqagandomabadi V1, Barone R1, Macaluso F1, D’Amico D1, Sausa M1, Carini F1, Di Felice V1 and David S1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy
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miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells
511PDF: 356Supplementary: 58HTML: 21 -
Essential Current Concepts in Stem Cell Biology
2779PDF: 499HTML: 10 -
From fix to fit into the autoptic human brains
2126PDF: 1376HTML: 55 -
RNA therapeutics - Function, design and delivery
929PDF: 450HTML: 175 -
USE OF HIGH-DEFINITION IMAGING FLOW CYTOMETRY AND A.I. TO ENUMERATE AND CHARACTERISE CIRCULATING TUMOUR CELLS S. Saravi1, S. Panfilov2, E. Karteris2 | 1College of Health, Medicine and Life Sciences, Brunel University of London, UK; 2College of Health, Medicine and Life Sciences, Brunel University of London, UK
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P73 | ANALYSIS OF SAPK/JNK PATHWAY IN DOXORUBICIN INDUCED ADIPOSE-DERIVED STEM CELL CYTOTOXICITY A. Skubis-Sikora, B. Sikora, K. Pogoda-Mieszczak, E. Bogunia, P. Czekaj | Department of Cytophysiology, Chair of Histology and Embryology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Poland
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EXPLORING NEURON–GLIOMA SIGNALING THROUGH IN VITRO CO-CULTURES Nicorvo E¹, Ferraro A¹, Pacca P¹, Boido M¹, Di Cunto F¹ and Vercelli A¹ | ¹Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy
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P38 | THE ROLE OF SPEXIN IN COLORECTAL CANCER J. Kiezun1, J. Godlewski1, M. Kiezun2, M. Gudelska1, K. Kisielewska1, A. E. Kowalczyk1, B. E. Krazinski1 | 1Department of Anatomy and Histology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland; 2Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Poland
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Histochemistry for nanomedicine: Novelty in tradition
1179PDF: 491HTML: 21 -
EXPRESSION OF PIEZO1 IN CLEAR CELL RENAL CELL CARCINOMA: INSIGHTS FROM BIOINFORMATIC AND IMMUNOHISTOCHEMICAL ANALYSES D. Jerka1, P. Antosik2, K. Bonowicz1,3, D. Grzanka4, M. Gagat1,3 | 1Department of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland; 2Department of Dermatology and Venerology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland; 3Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Płock, Poland; 4Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland
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P29 | AUTOPHAGY IS IMPAIRED IN GSCS-ENRICHED GLIOBLASTOMA MODELS G. Trotto1, M. Calvitto1, N. Martella1, D.Gargano1, M. Cillo2, E. Sgambati1, F. Nazio3, P. Grumati2|4, S. Di Bartolomeo1 | 1Dept. of Biosciences and Territory, University of Molise, Italy; 2Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy; 3Dept. of Biology, "Tor Vergata" University, Rome, Italy; 4Dept. of Clinical Medicine and Surgery, Federico II University, Naples, Italy
81PDF: 11 -
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Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway
1871PDF: 595Supplementary Figure: 91HTML: 61 -
AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in autophagy-induced astrocytoma cells
2069PDF: 1002Supplementary Figures: 314Supplementary Table: 230HTML: 504 -
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Sox9 expression in canine epithelial skin tumors
3202PDF: 895HTML: 408 -
P84 | OMOMYC PEPTIDE LOCALIZES IN THE NUCLEUS AND DISPLAYS ANTIPROLIFERATIVE EFFECTS ON CELLULAR MODELS OF HUMAN OSTEOSARCOMA I. Versari1, S. Salucci1, A. Bavelloni2, M. Traversari3, I. Faenza1 | 1Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy; 2Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; 3Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
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P09 | THERAPEUTIC POTENTIAL OF NEUROTROPHINS IN AUTISM SPECTRUM DISORDER F. D’Egidio1, M.S. Scenna1, M. d’Angelo1|2, V. Castelli1, A. Cimini1|2 | 1University of L’Aquila, Dpt. of Life, Health and Environmental Sciences, L’Aquila, Italy; 2Sbarro Institute for Cancer Research and Molecular Medicine and Center for Biotechnology, Temple University, Philadelphia, PA, USA
65PDF: 13 -
PO54 | FATTY INFILTRATION AND POTENTIAL ADIPOGENIC SHIFT OF SKELETAL MUSCLE CELLS: MULTIPARAMETRIC HISTOLOGICAL ANALYSIS OF MYOSTEATOSIS L. Morello1, G. Stati1, V. Giansante1, S. Lattanzio1, P. Cerritelli1, D. Bruni1, S. Cinti2, R. Di Pietro1,3,4 | 1Department of Medicine and Aging Sciences, “G. d’ Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Experimental and Clinical Medicine, Center of Obesity, Polytechnic University of Marche, Ancona, Italy; 3StemTeCh Group, G. d’ Annunzio Foundation, “G. d’ Annunzio” University of Chieti Pescara, Chieti, Italy; 4Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA
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Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice
1759PDF: 882Supplementary: 132HTML: 35 -
Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor
2509PDF: 798Supplementary: 285HTML: 17
