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MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices
2719PDF: 1300MIAQuant user Manual: 346MIAQuant source code: 427HTML: 114 -
EXPLORING THE CYTOTOXIC AND APOPTOTIC ACTIVITIES OF PRUNUS SPINOSA ECOTYPE EXTRACT TRIGNO ON 3D AND 2D MODELS OF HUMAN CANCER CELLS A. Di Netta1, A. Di Pauli2, R. Vona3, C. Cittadini3, S. Meschini1, M. Condello1 | 1 National Center for Drug Research and Evaluation, National Institute of Health, Rome, Italy; 2 Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, «Sapienza» University of Rome, Rome, Italy: 3 National Center for Gender-Specific Medicine, National Institute of Health, Rome, Italy
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Decreased expression of Met during differentiation in rat lung
1776PDF: 903Supplementary: 383HTML: 321 -
REDUCING PACLITAXEL-INDUCED PERIPHERAL NEUROTOXICITY VIA LIPOSOMAL DRUG TARGETING Molteni L1, Persico A2, Kravicz M3, Antoniou A4, Peqini K4, Mantecca P2, Nicolini G1, Pellegrino S4, Re F3 and Bragato C2 | 1Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; 2POLARIS Research Center, Dept. of Earth and Environmental Sciences, University of Milano-Bicocca, Milan, Italy; 3School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; 4Department of Pharmaceutical Sciences, University of Milan, Milan, Italy
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PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage
3299PDF: 857Supplementary: 381HTML: 835 -
34 | CYTOTOXIC EFFECTS OF SICILIAN GRAPE SEED OILS ON CANCER CELLS D. Ganci1, G. Abruscato2, R. Chiarelli1, M. Mauro1|2, V. Arizza1|2, M. Vazzana1|2, C. Luparello1|2 | 1Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2NFBC, National Biodiversity Future Center, Palermo, Italy
169PDF: 99 -
22 | TRANSCRIPTIONAL AND POST-TRANSLATIONAL NETWORKS COORDINATE SELECTIVE AUTOPHAGY TO MAINTAIN ORGANELLE HOMEOSTASIS K. Hartfelt1, M. Petraroia2, T. Persichini2, M. Colasanti2, C. Di Malta3, F. Cecconi4, V. Cianfanelli2 | 1Unit of Cell Stress and Survival, Danish Cancer Institute, Copenhagen, Denmark; 2Dept. of Science, University Roma TRE, Rome, Italy; 3Telethon Institute of Genetics and Medicine, Naples, Italy; 4Dept. of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics Research, Catholic University of the Sacred Heart, Rome, Italy
217PDF: 139 -
P81 | AN IN VITRO CYTOTOXIC, PROAPOPTOTIC AND ANTITUMOR ACTIVITY ASSESSMENT FOR CERAMIDASE INHIBITORS ON HUMAN LARYNGEAL CANCER CELLS C. Vejselova Sezer1, M. Cengiz2, B. Gür3, R. Dündar4, C. Cingi5, H.M. Kutlu6 | 1Department of Biology, Kutahya Dumlupinar University, Kutahya, Türkiye; 2Department of Mathematics and Physical Sciences Education, Siirt University, Siirt, Türkiye; 3Department of Biochemistry, Iğdır University, Iğdır, Türkiye; 4Department of Otorhinolaryngology, Acibadem Eskişehir Hospital, Eskişehir, Türkiye; 5Department of Otorhinolaryngology, Eskişehir Osmangazi University, Eskişehir, Türkiye; 6Department of Biology, Eskişehir Technical University, Eskişehir, Türkiye
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TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti1, M. C. Gagliani2, G. Bellese2, M. Crippa3, A. Abbona4, M. Paccagnella4, P. Arnaldi5, M. C. Merlano6, O. Garrone7, A.M. Porcelli8, M. Matteoli1, P. Falletta9, P. Castagnola10, K. Cortese2 | 1IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; 2DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; 3Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; 4Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; 5IRCCS Ospedale Policlinico San Martino, Genova, Italy; 6Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; 7Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 8FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; 9Vita-Salute San Raffaele University, Milan, Italy; 10IRCCS Ospedale Policlinico San Martino, Genova, Italy
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Stem Cells and Therapy: Emerging Approaches
2261PDF: 450HTML: 39 -
P28 | EXPLORING THE POTENTIAL LINK BETWEEN MITOCHONDRIAL DYSFUNCTION AND MITO-EVS IN PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) V. Giansante1, L. Leanza2, E. Guerra3, F. Vianello4, C. Iacovino1, S. Lattanzio1, L. Morello1, G. Stati1, P. Simeone3, P. Lanuti3, S. Alberti5, M. Reichert6, R. Di Pietro1 | 1Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Biology, University of Padua, Padua, Italy; 3Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST)G. d’Annunzio” University of Chieti-Pescara, Italy; 4Department of Biology, University of Padua, Padua, Italy; 5Unit of Medical Genetics, Department of Biomedical Sciences, University of Messina, Messina, Italy; 6Translational Pancreatic Cancer Research Center, Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Center for Organoid Systems (COS), Technical University of Munich, Garching, Germany
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miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells
694PDF: 632Supplementary: 107HTML: 53 -
Essential Current Concepts in Stem Cell Biology
3007PDF: 581HTML: 48 -
From fix to fit into the autoptic human brains
2276PDF: 1478HTML: 89 -
RNA therapeutics - Function, design and delivery
977PDF: 503HTML: 184 -
USE OF HIGH-DEFINITION IMAGING FLOW CYTOMETRY AND A.I. TO ENUMERATE AND CHARACTERISE CIRCULATING TUMOUR CELLS S. Saravi1, S. Panfilov2, E. Karteris2 | 1College of Health, Medicine and Life Sciences, Brunel University of London, UK; 2College of Health, Medicine and Life Sciences, Brunel University of London, UK
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P73 | ANALYSIS OF SAPK/JNK PATHWAY IN DOXORUBICIN INDUCED ADIPOSE-DERIVED STEM CELL CYTOTOXICITY A. Skubis-Sikora, B. Sikora, K. Pogoda-Mieszczak, E. Bogunia, P. Czekaj | Department of Cytophysiology, Chair of Histology and Embryology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Poland
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EXPLORING NEURON–GLIOMA SIGNALING THROUGH IN VITRO CO-CULTURES Nicorvo E¹, Ferraro A¹, Pacca P¹, Boido M¹, Di Cunto F¹ and Vercelli A¹ | ¹Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy
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P38 | THE ROLE OF SPEXIN IN COLORECTAL CANCER J. Kiezun1, J. Godlewski1, M. Kiezun2, M. Gudelska1, K. Kisielewska1, A. E. Kowalczyk1, B. E. Krazinski1 | 1Department of Anatomy and Histology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland; 2Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Poland
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Histochemistry for nanomedicine: Novelty in tradition
1294PDF: 620HTML: 62 -
EXPRESSION OF PIEZO1 IN CLEAR CELL RENAL CELL CARCINOMA: INSIGHTS FROM BIOINFORMATIC AND IMMUNOHISTOCHEMICAL ANALYSES D. Jerka1, P. Antosik2, K. Bonowicz1,3, D. Grzanka4, M. Gagat1,3 | 1Department of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland; 2Department of Dermatology and Venerology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland; 3Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Płock, Poland; 4Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland
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Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway
2057PDF: 719Supplementary Figure: 148HTML: 91 -
AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in autophagy-induced astrocytoma cells
2192PDF: 1101Supplementary Figures: 384Supplementary Table: 287HTML: 543 -
THE USE OF BIOMIMETIC 2D AND 3D UROTHELIAL IN VITRO MODELS WITH MOLECULAR, MORPHOLOGICAL AND FUNCTIONAL CHARACTERISTICS OF NORMAL AND CANCEROUS BLADDER TISSUE AS AN ALTERNATIVE METHOD IN PRECLINICAL STUDIES M.E. Kreft1, L. Tratnjek1, A. Janev1, N. Resnik1, U. Cerkvenik1, U. D. Jerman1, G. Markovič1, T.Ž. Ramuta1, T. Višnjar1, Ž. Sardoč1, A.Punčuh1, S. Kralj2, M. Čemažar3, P. Veranič1 |1Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; 2Department for Materials Synthesis, Jožef Stefan Institute, Ljubljana, Slovenia; 3Institute of Oncology Ljubljana, Ljubljana, Slovenia
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P29 | AUTOPHAGY IS IMPAIRED IN GSCS-ENRICHED GLIOBLASTOMA MODELS G. Trotto1, M. Calvitto1, N. Martella1, D.Gargano1, M. Cillo2, E. Sgambati1, F. Nazio3, P. Grumati2|4, S. Di Bartolomeo1 | 1Dept. of Biosciences and Territory, University of Molise, Italy; 2Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy; 3Dept. of Biology, "Tor Vergata" University, Rome, Italy; 4Dept. of Clinical Medicine and Surgery, Federico II University, Naples, Italy
167PDF: 90 -
PURKINJE CELL INTEGRITY IS PRESERVED BY EXERCISE IN PARANEOPLASTIC CEREBELLAR DEGENERATION: EVIDENCE FROM A CANCER CACHEXIA MOUSE MODEL Zummo FP1, Saqagandomabadi V1, Barone R1, Macaluso F1, D’Amico D1, Sausa M1, Carini F1, Di Felice V1 and David S1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy
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Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor
2761PDF: 900Supplementary: 345HTML: 41 -
P19 | IDENTIFICATION OF MIR-129-5P AS A COMMON REGULATOR OF E3 UBIQUITIN LIGASES WITH A POTENTIAL ROLE IN GLIOBLASTOMA PROGRESSION N. Martella1, A.B. Díaz Méndez2, G. Regazzo2, G.F. Bufalieri3, A. Frati4, A. Arcella4, L. Di Marcotullio3, M.G. Rizzo2, S. Di Bartolomeo1 | 1Dept. of Biosciences and Territory, University of Molise, Italy; 2Dept. of Research, Advanced Diagnostics and Technological Innovation, Translational Oncology Research Unit, IRCCS -Regina Elena National Cancer Institute, Rome, Italy; 3Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy; 4IRCCS Neuromed, Pozzilli (IS), Italy
158PDF: 93 -
CHEMOTHERAPY-INDUCED REMODELING OF CORTICAL PYRAMIDAL NEURONS: MORPHOLOGICAL EFFECTS OF OXALIPLATIN AND PACLITAXEL Iezzi G1,2, Marmiroli P3,4, Vercelli A1,2 and Cavaletti G3,4 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi,Turin, Italy; 3University of Milano-Bicocca, Italy; 4Experimental Neurology Unit, Monza, Italy
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Functional topography of the fully grown human oocyte
2266PDF: 1000HTML: 303
