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PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage
3094PDF: 761Supplementary: 319HTML: 814 -
34 | CYTOTOXIC EFFECTS OF SICILIAN GRAPE SEED OILS ON CANCER CELLS D. Ganci1, G. Abruscato2, R. Chiarelli1, M. Mauro1|2, V. Arizza1|2, M. Vazzana1|2, C. Luparello1|2 | 1Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2NFBC, National Biodiversity Future Center, Palermo, Italy
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22 | TRANSCRIPTIONAL AND POST-TRANSLATIONAL NETWORKS COORDINATE SELECTIVE AUTOPHAGY TO MAINTAIN ORGANELLE HOMEOSTASIS K. Hartfelt1, M. Petraroia2, T. Persichini2, M. Colasanti2, C. Di Malta3, F. Cecconi4, V. Cianfanelli2 | 1Unit of Cell Stress and Survival, Danish Cancer Institute, Copenhagen, Denmark; 2Dept. of Science, University Roma TRE, Rome, Italy; 3Telethon Institute of Genetics and Medicine, Naples, Italy; 4Dept. of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics Research, Catholic University of the Sacred Heart, Rome, Italy
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P81 | AN IN VITRO CYTOTOXIC, PROAPOPTOTIC AND ANTITUMOR ACTIVITY ASSESSMENT FOR CERAMIDASE INHIBITORS ON HUMAN LARYNGEAL CANCER CELLS C. Vejselova Sezer1, M. Cengiz2, B. Gür3, R. Dündar4, C. Cingi5, H.M. Kutlu6 | 1Department of Biology, Kutahya Dumlupinar University, Kutahya, Türkiye; 2Department of Mathematics and Physical Sciences Education, Siirt University, Siirt, Türkiye; 3Department of Biochemistry, Iğdır University, Iğdır, Türkiye; 4Department of Otorhinolaryngology, Acibadem Eskişehir Hospital, Eskişehir, Türkiye; 5Department of Otorhinolaryngology, Eskişehir Osmangazi University, Eskişehir, Türkiye; 6Department of Biology, Eskişehir Technical University, Eskişehir, Türkiye
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TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti1, M. C. Gagliani2, G. Bellese2, M. Crippa3, A. Abbona4, M. Paccagnella4, P. Arnaldi5, M. C. Merlano6, O. Garrone7, A.M. Porcelli8, M. Matteoli1, P. Falletta9, P. Castagnola10, K. Cortese2 | 1IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; 2DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; 3Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; 4Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; 5IRCCS Ospedale Policlinico San Martino, Genova, Italy; 6Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; 7Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 8FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; 9Vita-Salute San Raffaele University, Milan, Italy; 10IRCCS Ospedale Policlinico San Martino, Genova, Italy
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Stem Cells and Therapy: Emerging Approaches
2062PDF: 385HTML: 10 -
P28 | EXPLORING THE POTENTIAL LINK BETWEEN MITOCHONDRIAL DYSFUNCTION AND MITO-EVS IN PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) V. Giansante1, L. Leanza2, E. Guerra3, F. Vianello4, C. Iacovino1, S. Lattanzio1, L. Morello1, G. Stati1, P. Simeone3, P. Lanuti3, S. Alberti5, M. Reichert6, R. Di Pietro1 | 1Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Biology, University of Padua, Padua, Italy; 3Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST)G. d’Annunzio” University of Chieti-Pescara, Italy; 4Department of Biology, University of Padua, Padua, Italy; 5Unit of Medical Genetics, Department of Biomedical Sciences, University of Messina, Messina, Italy; 6Translational Pancreatic Cancer Research Center, Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Center for Organoid Systems (COS), Technical University of Munich, Garching, Germany
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ANTIBODY-TO-IMAGING PIPELINE TO MONITOR DRUG-TARGET ENGAGEMENT IN BREAST TUMORS M. Barroso | Department of Molecular and Cellular Physiology Albany Medical College, Albany NY 12208, USA
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P31 | MORPHOLOGICAL AND ULTRASTRUCTURAL MARKERS OF RADIATION-INDUCED ADIPOSE TISSUE DAMAGE E. Guerra1, S. Lattanzio1, G. Furini2, G. Scabia2, E. Mota-Silva2, M. Maffei2, S. Cinti3, R. Di Pietro1 | 1Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2CNR Institute of Clinical Physiology, Pisa, Italy; 3Department of Experimental and Clinical Medicine, Center of Obesity, Università Politecnica delle Marche (Polytechnic University of Marche), Ancona, Italy
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On the future contents of a small journal of histochemistry
2535PDF: 982HTML: 941 -
RNA therapeutics - Function, design and delivery
928PDF: 447HTML: 174 -
USE OF HIGH-DEFINITION IMAGING FLOW CYTOMETRY AND A.I. TO ENUMERATE AND CHARACTERISE CIRCULATING TUMOUR CELLS S. Saravi1, S. Panfilov2, E. Karteris2 | 1College of Health, Medicine and Life Sciences, Brunel University of London, UK; 2College of Health, Medicine and Life Sciences, Brunel University of London, UK
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P73 | ANALYSIS OF SAPK/JNK PATHWAY IN DOXORUBICIN INDUCED ADIPOSE-DERIVED STEM CELL CYTOTOXICITY A. Skubis-Sikora, B. Sikora, K. Pogoda-Mieszczak, E. Bogunia, P. Czekaj | Department of Cytophysiology, Chair of Histology and Embryology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Poland
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EXPLORING NEURON–GLIOMA SIGNALING THROUGH IN VITRO CO-CULTURES Nicorvo E¹, Ferraro A¹, Pacca P¹, Boido M¹, Di Cunto F¹ and Vercelli A¹ | ¹Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy
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P38 | THE ROLE OF SPEXIN IN COLORECTAL CANCER J. Kiezun1, J. Godlewski1, M. Kiezun2, M. Gudelska1, K. Kisielewska1, A. E. Kowalczyk1, B. E. Krazinski1 | 1Department of Anatomy and Histology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland; 2Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Poland
200 -
Histochemistry for nanomedicine: Novelty in tradition
1149PDF: 486HTML: 20 -
EXPRESSION OF PIEZO1 IN CLEAR CELL RENAL CELL CARCINOMA: INSIGHTS FROM BIOINFORMATIC AND IMMUNOHISTOCHEMICAL ANALYSES D. Jerka1, P. Antosik2, K. Bonowicz1,3, D. Grzanka4, M. Gagat1,3 | 1Department of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland; 2Department of Dermatology and Venerology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland; 3Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Płock, Poland; 4Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland
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Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway
1842PDF: 589Supplementary Figure: 89HTML: 61 -
AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in autophagy-induced astrocytoma cells
2055PDF: 995Supplementary Figures: 314Supplementary Table: 230HTML: 504 -
P29 | AUTOPHAGY IS IMPAIRED IN GSCS-ENRICHED GLIOBLASTOMA MODELS G. Trotto1, M. Calvitto1, N. Martella1, D.Gargano1, M. Cillo2, E. Sgambati1, F. Nazio3, P. Grumati2|4, S. Di Bartolomeo1 | 1Dept. of Biosciences and Territory, University of Molise, Italy; 2Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy; 3Dept. of Biology, "Tor Vergata" University, Rome, Italy; 4Dept. of Clinical Medicine and Surgery, Federico II University, Naples, Italy
56PDF: 3 -
THE USE OF BIOMIMETIC 2D AND 3D UROTHELIAL IN VITRO MODELS WITH MOLECULAR, MORPHOLOGICAL AND FUNCTIONAL CHARACTERISTICS OF NORMAL AND CANCEROUS BLADDER TISSUE AS AN ALTERNATIVE METHOD IN PRECLINICAL STUDIES M.E. Kreft1, L. Tratnjek1, A. Janev1, N. Resnik1, U. Cerkvenik1, U. D. Jerman1, G. Markovič1, T.Ž. Ramuta1, T. Višnjar1, Ž. Sardoč1, A.Punčuh1, S. Kralj2, M. Čemažar3, P. Veranič1 |1Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; 2Department for Materials Synthesis, Jožef Stefan Institute, Ljubljana, Slovenia; 3Institute of Oncology Ljubljana, Ljubljana, Slovenia
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PURKINJE CELL INTEGRITY IS PRESERVED BY EXERCISE IN PARANEOPLASTIC CEREBELLAR DEGENERATION: EVIDENCE FROM A CANCER CACHEXIA MOUSE MODEL Zummo FP1, Saqagandomabadi V1, Barone R1, Macaluso F1, D’Amico D1, Sausa M1, Carini F1, Di Felice V1 and David S1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy
282 -
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells
497PDF: 344Supplementary: 58HTML: 20 -
Essential Current Concepts in Stem Cell Biology
2725PDF: 497HTML: 10 -
From fix to fit into the autoptic human brains
2079PDF: 1372HTML: 54 -
ADVANCEMENTS AND EMERGING PERSPECTIVES IN MICROSCOPIC IMAGING S. Karahuseyinoglu | Department of Histology & Embryology, Koc University, School of Medicine, Istanbul, Turkiye
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P09 | THERAPEUTIC POTENTIAL OF NEUROTROPHINS IN AUTISM SPECTRUM DISORDER F. D’Egidio1, M.S. Scenna1, M. d’Angelo1|2, V. Castelli1, A. Cimini1|2 | 1University of L’Aquila, Dpt. of Life, Health and Environmental Sciences, L’Aquila, Italy; 2Sbarro Institute for Cancer Research and Molecular Medicine and Center for Biotechnology, Temple University, Philadelphia, PA, USA
51PDF: 4 -
P64 | EX VIVO EXTRACTION OF GLIOMA SECRETOME: A NOVEL MICROENVIRONMENT-BASED PROTOCOL FOR METABOLIC AND MOLECULAR PROFILING I. Neri1, M.V. Marvi1, V. Righi2, V. Papa3, E. Boschetti1, S. Blando1, E. Franceschi4, M. Zoli4, D. Mazzatenta4, N. Neri4, A. Vignaroli4, L. Cocco1, L. Manzoli1, S. Ratti1 | 1Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Department of Life Quality Sciences, University of Bologna, Bologna, Italy; 3IRCCS St. Orsola, Bologna, Italy; 4IRCCS Institute of Neurological Sciences of Bologna, Bologna, Italy
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THERAPEUTIC VERSUS PREVENTIVE ADMINISTRATION OF NEUROACTIVE STEROIDS TO TREAT BORTEZOMIB-INDUCED PAINFUL NEUROPATHY Iseppon F1, Tonelli E1,2, Fabbro V1, Chiorazzi A1, Canta A1, Alberti P1, Carozzi VA1, Pozzi E1, Cherchi L1,2, Fermi S1,2, Segmani I1,2, Fantoni L1, Rodriguez-Menendez V1, Ballarini E1, Cavaletti G1 and Meregalli C1 | 1University of Milano-Bicocca, Department of Medicine and Surgery, Monza, Italy; 2University of Milano-Bicocca, PhD Program in Neuroscience, Monza, Italy
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