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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation

    Yuejuan Cao, Li Cui, Shaoyong Tuo, Hongze Liu, Shaonan Cui
    24-04-2024
    https://doi.org/10.4081/ejh.2024.4004
    1600
    PDF: 387
    HTML: 17
  • circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

    Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao
    22-08-2025
    https://doi.org/10.4081/ejh.2025.4230
    242
    PDF: 185
    HTML: 2
  • Expression profile of the zinc transporter ZnT3 in taste cells of rat circumvallate papillae and its role in zinc release, a potential mechanism for taste stimulation

    Kentaro Nishida, Saho Bansho, Akiko Ikukawa, Teruyo Kubota, Akihiro Ohishi, Kazuki Nagasawa
    10-11-2022
    https://doi.org/10.4081/ejh.2022.3534
    1158
    PDF: 651
    Supplementary: 128
    HTML: 30
  • Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

    Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3412
    2058
    PDF: 1235
    HTML: 27
  • ATP metabolizing enzymes ENPP1, 2 and 3 are localized in sensory neurons of rat dorsal root ganglion

    Kentaro Nishida, Yuka Nomura, Kanako Kawamori, Akihiro Ohishi, Kazuki Nagasawa
    09-04-2018
    https://doi.org/10.4081/ejh.2018.2877
    2642
    PDF: 957
    Supplementary: 230
    HTML: 53
  • SerpinB3 administration protects liver against ischemia-reperfusion injury

    Cristian Turato, Mariapia Vairetti, Marta Cagna, Alessandra Biasiolo, Andrea Ferrigno, Santina Quarta, Mariagrazia Ruvoletto, Silvia De Siervi, Patrizia Pontisso, Laura Giuseppina Di Pasqua
    28-10-2022
    https://doi.org/10.4081/ejh.2022.3561
    1131
    PDF: 679
    HTML: 32
  • Cellular and tissue expression of DAPIT, a phylogenetically conserved peptide

    H. Kontro, J.J. Hulmi, P. Rahkila, H. Kainulainen
    e18
    22-05-2012
    https://doi.org/10.4081/ejh.2012.18
    1466
    PDF: 653
    HTML: 4797
  • Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

    Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan
    13-05-2024
    https://doi.org/10.4081/ejh.2024.3917
    1384
    PDF: 516
    HTML: 26
  • Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

    V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas
    e5
    08-02-2011
    https://doi.org/10.4081/ejh.2011.e5
    1289
    PDF: 728
    HTML: 3445
  • Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker’s organ in vivo in early stage after birth in rats

    Jun Liu, Linbin Cai, Yuanyuan He, Jun Yang
    07-08-2017
    https://doi.org/10.4081/ejh.2017.2706
    2183
    PDF: 690
    HTML: 208
  • Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

    Jun Lin, Liping Jiang, Kun Guo, Ning Feng
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3528
    1685
    PDF: 1061
    Supplementary: 91
    HTML: 28
  • The fuss over lipo“fussâ€cin: not all autofluorescence is the same

    B. Sainz Jr., I. Miranda-Lorenzo, C. Heeschen
    12-03-2015
    https://doi.org/10.4081/ejh.2015.2512
    2240
    PDF: 850
    HTML: 1320
  • Developmental expression of inositol 1, 4, 5-trisphosphate receptor in the post-natal rat cochlea

    W.J. Liu, J. Yang
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2486
    2060
    PDF: 714
    HTML: 1024
  • Dipeptidylpeptidase-IV activity and expression reveal decreased damage to the intrahepatic biliary tree in fatty livers submitted to subnormothermic machine-perfusion respect to conventional cold storage

    E. Tarantola, V. Bertone, G. Milanesi, C. Gruppi, A. Ferrigno, M. Vairetti, S. Barni, I. Freitas
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2414
    1685
    PDF: 745
    HTML: 565
  • Maturation of neurotransmission in the developing rat cochlea: immunohistochemical evidence from differential expression of synaptophysin and synaptobrevin 2

    S. He, J. Yang
    e2
    18-01-2011
    https://doi.org/10.4081/ejh.2011.e2
    1134
    PDF: 500
    HTML: 2025
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    2652
    PDF: 1517
    Video 1: 210
    Video 2: 234
    HTML: 19
  • PARP-1 protein expression in glioblastoma multiforme

    A. Galia, A.E. Calogero, R. Condorelli, F. Fraggetta, A. La Corte, F. Ridolfo, P. Bosco, R. Castiglione, M. Salemi
    e9
    27-02-2012
    https://doi.org/10.4081/ejh.2012.e9
    2832
    PDF: 1143
    HTML: 1764
  • Varying effects of EGF, HGF and TGFβ on formation of invadopodia and invasiveness of melanoma cell lines of different origin

    A. Makowiecka, A. Simiczyjew, D. Nowak, A.J. Mazur
    09-12-2016
    https://doi.org/10.4081/ejh.2016.2728
    2023
    PDF: 842
    Supplementary: 261
    HTML: 411
  • Maternal dietary loads of alpha-tocopherol increase synapse density and glial synaptic coverage in the hippocampus of adult offspring

    S. Salucci, P. Ambrogini, D. Lattanzi, M. Betti, P. Gobbi, C. Galati, F. Galli, R. Cuppini, A. Minelli
    02-05-2014
    https://doi.org/10.4081/ejh.2014.2355
    1992
    PDF: 862
    HTML: 461
  • Site-directed mutagenesis, in vivo electroporation and mass spectrometry in search for determinants of the subcellular targeting of Rab7b paralogue in the model eukaryote Paramecium octaurelia

    E. Wyroba, P. Kwaśniak, K. Miller, K. Kobyłecki, M. Osińska
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2612
    1701
    PDF: 772
    HTML: 330
  • The earthworm Dendrobaena veneta (Annelida): A new experimental-organism for photobiomodulation and wound healing

    Andrea Amaroli, Sara Ferrando, Marina Pozzolini, Lorenzo Gallus, Steven Parker, Stefano Benedicenti
    09-02-2018
    https://doi.org/10.4081/ejh.2018.2867
    1946
    PDF: 857
    HTML: 53
  • Cytochemical localization and quantification of plasma membrane Ca2+-ATPase activity in mollusc digestive gland cells

    G Pons, V Evangelisti, F Caprì, S Mozzone, A Viarengo
    31-40
    30-12-2009
    https://doi.org/10.4081/1652
    596
    PDF: 538
  • Stretching prior to resistance training promotes adaptations on the postsynaptic region in different myofiber types

    Carolina dos Santos Jacob, Gabriela Klein Barbosa, Mariana Pasquini Rodrigues, Jurandyr Pimentel Neto, Lara Caetano Rocha, Adriano Polican Ciena
    15-02-2022
    https://doi.org/10.4081/ejh.2022.3356
    1639
    PDF: 691
    HTML: 37
  • 5XFAD MOUSE MODEL: INVESTIGATING BRAIN IRON IMBALANCE AND MITOCHONDRIAL FEATURES’ ALTERATION Mezzanotte M1, Chicote J1, Scimia N1, Riganti C2, Porporato PE3 and Stanga S1 | 1Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; 2Department of Oncology, Oncological Pharmacology Lab, University of Turin, Italy; 3Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4502
    135
  • New light in flavin autofluorescence

    A.C. Croce, G. Bottiroli
    10-11-2015
    https://doi.org/10.4081/ejh.2015.2576
    2096
    PDF: 887
    HTML: 336
  • Expression of ATP sensitive K+ channel subunit Kir6.1 in rat kidney

    M Zhou, HJ He, R Suzuki, O Tanaka, M Sekiguchi, Y Yasuoka, K Kawahara, H Itoh, H Abe
    43-52
    30-06-2009
    https://doi.org/10.4081/1011
    615
    PDF: 519
  • Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability

    Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3352
    1493
    PDF: 663
    HTML: 26
  • Evidence that muscle cells do not express the histidine-rich glycoprotein associated with AMP deaminase but can internalise the plasma protein

    A.R.M. Sabbatini, L. Mattii, B. Battolla, E. Polizzi, D. Martini, M. Ranieri-Raggi, A.J.G. Moir, A. Raggi
    e6
    25-02-2011
    https://doi.org/10.4081/ejh.2011.e6
    1311
    PDF: 468
    HTML: 2593
  • Calcium-induced alteration of mitochondrial morphology and mitochondrial-endoplasmic reticulum contacts in rat brown adipocytes

    I. Golic, K. Velickovic, M. Markelic, A. Stancic, A. Jankovic, M. Vucetic, V. Otasevic, B. Buzadzic, B. Korac, A. Korac
    09-09-2014
    https://doi.org/10.4081/ejh.2014.2377
    3209
    PDF: 1026
    HTML: 1544
  • Subcellular distribution and expression of cofilin and ezrin in human colon adenocarcinoma cell lines with different metastatic potential

    D. Nowak, A. J. Mazur, A. Popow-Woźniak, A. Radwańska, H. G. Mannherz, M. Malicka-Błaszkiewicz
    e14
    13-04-2010
    https://doi.org/10.4081/ejh.2010.e14
    1570
    PDF: 590
    HTML: 2647
  • P65 | (YS) INVESTIGATING THE EFFECTS OF THE SECRETOME FROM HUMAN AMNIOTIC MESENCHYMAL STROMAL CELLS ON INFLAMMASOME ACTIVATION M. Rossi1, M. Magatti2, P. Romele2, E. Vertua2, E. Giuzzi2, S. Farigu2, L. Marelli2, B. Rapuzzi2, S. De Munari2, A. Silini2, O. Parolini3 | 1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, and Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 2Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 3Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy & Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4390
    171
  • Contribution of intestinal smooth muscle to Crohn's disease fibrogenesis

    C. Severi, R. Sferra, A. Scirocco, A. Vetuschi, N. Pallotta, A. Pronio, R. Caronna, G. Di Rocco, E. Gaudio, E. Corazziari, P. Onori
    17-12-2014
    https://doi.org/10.4081/ejh.2014.2457
    2708
    PDF: 1030
    HTML: 431
  • Colorimetric and fluorescent TRAP assays for visualising and quantifying fish osteoclast activity

    Lalith Prabha Ethiraj, En Lei Samuel Fong, Ranran Liu, Madelynn Chan, Christoph Winkler, Tom James Carney
    24-03-2022
    https://doi.org/10.4081/ejh.2022.3369
    2009
    PDF: 1401
    HTML: 83
  • pPKCα mediated-HIF-1α activation related to the morphological modifications occurring in neonatal myocardial tissue in response to severe and mild hyperoxia

    S. Zara, V. Macchi, R. De Caro, M. Rapino, A. Cataldi, A. Porzionato
    e2
    31-01-2012
    https://doi.org/10.4081/ejh.2012.e2
    1571
    PDF: 2348
    HTML: 2472
  • The role of galanin in the progression and prognosis of colorectal cancer: the unfinished story

    Zbigniew Kmiec, Jacek Kieżun, Bartlomiej E. Krazinski, Przemyslaw Kwiatkowski, Janusz Godlewski
    06-03-2024
    https://doi.org/10.4081/ejh.2024.3990
    1242
    PDF: 377
    HTML: 9
  • Correlation between PARP-1 immunoreactivity and cytomorphological features of parthanatos, a specific cellular death in breast cancer cells

    P. Donizy, A. Halon, P. Surowiak, G. Pietrzyk, C. Kozyra, R. Matkowski
    e35
    20-11-2013
    https://doi.org/10.4081/ejh.2013.e35
    3528
    PDF: 741
    HTML: 328
  • Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

    A.C. Croce, G. Bottiroli
    12-12-2014
    https://doi.org/10.4081/ejh.2014.2461
    12604
    PDF: 5338
    HTML: 7944
  • Co-overexpression of bcl-2 and c-myc in uterine cervix carcinomas and premalignant lesions

    Z. Protrka, S. Arsenijevic, A. Dimitrijevic, S. Mitrovic, V. Stankovic, M. Milosavljevic, T. Kastratovic, J. Djuric
    e8
    16-03-2011
    https://doi.org/10.4081/ejh.2011.e8
    972
    PDF: 567
    HTML: 3022
  • Curculigoside inhibits osteoarthritis via the regulation of NLRP3 pathway

    Xufei Wang, Yinlian Liu, Yongnian Zhou, Yang Zhou, Yueping Li
    13-12-2023
    https://doi.org/10.4081/ejh.2023.3896
    1168
    PDF: 569
    HTML: 13
  • New insights into the in situ microscopic visualization and quantification of inorganic polyphosphate stores by 4',6-diamidino-2-phenylindole (DAPI)-staining

    F.M. Gomes, I.B. Ramos, C. Wendt, W. Girard-Dias, W. De Souza, E.A. Machado, K. Miranda
    e34
    05-11-2013
    https://doi.org/10.4081/ejh.2013.e34
    4138
    PDF: 1835
    HTML: 597
  • Targeting EphA2 suppresses the proliferation, migration and invasion of endometriosis via the AMPK signaling pathway

    Chaoyi Yang, Shujun Wang, Mengru Li, Xiangli Pang, Aili Tan
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4168
    367
    PDF: 192
    HTML: 10
  • Investigating conversion of endplate chondrocytes induced by intermittent cyclic mechanical unconfined compression in three-dimensional cultures

    H.G. Xu, W. Zhang, Q. Zheng, Y.F. Yu, L.F. Deng, H. Wang, P. Liu, M. Zhang
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2415
    1610
    PDF: 722
    HTML: 368
  • Expression of nestin, parvalbumin and otoferlin during cochlear development in the mouse: an immunofluorescence study

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Shujuan Yang
    22-09-2025
    https://doi.org/10.4081/ejh.2025.4242
    331
    PDF: 263
    Supplementary: 17
    HTML: 4
  • Sodium nitroprusside induces cell death and cytoskeleton degradation in adult rat cardiomyocytes in vitro: implications for anthracycline-induced cardiotoxicity

    M. Chiusa, F. Timolati, J.C. Perriard, T.M. Suter, C. Zuppinger
    e15
    16-04-2012
    https://doi.org/10.4081/ejh.2012.15
    1369
    PDF: 1120
    HTML: 4474
  • Lipids: Evergreen autofluorescent biomarkers for the liver functional profiling

    Anna Cleta Croce, Giovanni Bottiroli
    01-06-2017
    https://doi.org/10.4081/ejh.2017.2808
    1562
    PDF: 757
    HTML: 128
  • Expression of S100β during mouse cochlear development

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Lizhong Su
    10-03-2025
    https://doi.org/10.4081/ejh.2025.4189
    1169
    PDF: 240
    Supplementary: 38
    HTML: 4
  • Distribution of alpha-synuclein in normal human jejunum and its relations with the chemosensory and neuroendocrine system

    Arianna Casini, Romina Mancinelli, Caterina Loredana Mammola, Luigi Pannarale, Piero Chirletti, Paolo Onori, Rosa Vaccaro
    02-11-2021
    https://doi.org/10.4081/ejh.2021.3310
    2163
    PDF: 1065
    HTML: 59
  • CAPTURE-CAPIVASERTIB AND PROSTATE CANCER TARGETING: UNRAVELING RESISTANCE ELEMENTS M. Zavatti1, V. Serafin1, L. Antolini1, S. Bresolin2, L. Reggiani Bonetti3, S. Marmiroli1 | 1Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy; 2Pediatric Hematology, Oncology and Stem Cell Transplant Division, Women and Child Health Department, Padua University, Padua, Italy; 3Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia, Modena, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4277
    130
  • Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

    M. Costanzo, B. Cisterna, A. Vella, T. Cestari, V. Covi, G. Tabaracci, M. Malatesta
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2515
    2904
    PDF: 926
    HTML: 405
  • Effect of thyroxine on munc-18 and syntaxin-1 expression in dorsal hippocampus of adult-onset hypothyroid rats

    Y. Zhu, D. Ning, F. Wang, C. Liu, Y. Xu, X. Jia, D. Zhu
    e22
    22-05-2012
    https://doi.org/10.4081/ejh.2012.22
    949
    PDF: 474
    HTML: 1313
  • Gemst: a taylor-made combination that reverts neuroanatomical changes in stroke

    Arturo Mangas, Javier Yajeya, Noelia González, Isabel Ruiz, Marianny Pernía, Michel Geffard, Rafael Coveñas
    25-05-2017
    https://doi.org/10.4081/ejh.2017.2790
    1584
    PDF: 627
    HTML: 192
  • Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy

    Fenqiang Qi, Yuxin Deng, Wei Huang, Yanli Cai, Kelin Hong, Shui Xiang
    15-10-2024
    https://doi.org/10.4081/ejh.2024.4104
    1782
    PDF: 399
    HTML: 2
  • Novel understanding on genetic mechanisms of enteric neuropathies leading to severe gut dysmotility

    Francesca Bianco, Giulia Lattanzio, Luca Lorenzini, Chiara Diquigiovanni, Maurizio Mazzoni, Paolo Clavenzani, Laura Calzà, Luciana Giardino, Catia Sternini, Elena Bonora, Roberto De Giorgio
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3289
    2142
    PDF: 1169
    HTML: 47
  • HACAT CELLS AS A 2D EXPERIMENTAL DIFFERENTIATING MODEL TO ANALYZE THE EARLY BIOLOGICAL EFFECTS INDUCED BY A PSORIATIC PROINFLAMMATORY MICROENVIRONMENT: CELL PROLIFERATION, DIFFERENTIATION AND FERROPTOSIS F. Riva1, S. Recalcati2, E. Gammella2, D. Daluiso1, F. Prignano3, E. Donetti2 | 1Dept. Public Health, Experimental and Forensic Medicine; Histology and Embryology Unit, University of Pavia, Pavia, Italy; 2Dept. Biomedical Sciences for Health, University of Milan, Milan, Italy; 3Dept. Health Sciences, Section of Dermatology, University of Florence, Florence, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4293
    129
  • Preferentially regulated expression of connexin 43 in the developing spiral ganglion neurons and afferent terminals in post-natal rat cochlea

    W.J. Liu, J. Yang
    11-02-2015
    https://doi.org/10.4081/ejh.2015.2464
    1788
    PDF: 1123
    HTML: 920
  • Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

    Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2749
    5754
    PDF: 1260
    HTML: 386
  • Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment

    R.J. Bułdak, M. Skonieczna, Ł. Bułdak, N. Matysiak, Ł. Mielańczyk, G. Wyrobiec, M. Kukla, M. Michalski, K. Żwirska-Korczala
    12-09-2014
    https://doi.org/10.4081/ejh.2014.2408
    1959
    PDF: 732
    HTML: 568
  • Effects of hypophyseal or thymic allograft on thymus development in partially decerebrate chicken embryos: expression of PCNA and CD3 markers

    M. Aita, F. Benedetti, E. Carafelli, E. Caccia, N. Romano
    e37
    30-08-2010
    https://doi.org/10.4081/ejh.2010.e37
    1074
    PDF: 711
    HTML: 3912
  • P11 | DOMINO TRANSPLANTATION IN MNGIE: IS THE LIVER A SUITABLE GRAFT? E. Boschetti1, I. Neri1, S. Blando1, C. Malagelada2, L. Caporali3, R. D’Angelo4, R. Rinaldi4, S. Mongiorgi1, V. Carelli3, R. De Giorgio5, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum – University of Bologna, Italy; 2Digestive System Research Unit, University Hospital Vall d’Hebron; Barcelona, Spain; 3IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; 4IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 5Department of Translational Medicine, University of Ferrara, Ferrara, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4331
    143
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European Journal of Histochemistry

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pISSN: 1121-760X
eISSN: 2038-8306

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