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Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng

21-06-2022

https://doi.org/10.4081/ejh.2022.3412

2605

PDF: 1474

HTML: 36
Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma

Zhiyang Wang, Jing Li, Ziwei Liu, Ling Yue

20-03-2023

https://doi.org/10.4081/ejh.2023.3622

1508

PDF: 831

HTML: 41
Folic acid promotes autophagy to relieve metabolism-associated fatty liver disease by regulating NRF2

Yu Wen, Juan Luo, Chunjing Shi, Jie Wu

03-11-2025

https://doi.org/10.4081/ejh.2025.4309

976

PDF: 598

HTML: 39
Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi

22-05-2024

https://doi.org/10.4081/ejh.2024.4033

1312

PDF: 564

HTML: 22
Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang

07-12-2023

https://doi.org/10.4081/ejh.2023.3816

1239

PDF: 732

HTML: 40
Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway

Zhongzhu Tang, Lei Wang, Yunwang Chen, Xiaomin Zheng, Runyu Wang, Bingxue Liu, Shiqi Zhang, Huimin Wang

07-08-2023

https://doi.org/10.4081/ejh.2023.3719

2229

PDF: 1057

HTML: 30
Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro

Chiara Rita Inguscio, Flavia Carton, Barbara Cisterna, Manuela Rizzi, Francesca Boccafoschi, Gabriele Tabaracci, Manuela Malatesta

09-09-2024

https://doi.org/10.4081/ejh.2024.4106

1962

PDF: 331

HTML: 17
Ozone at low concentrations does not affect motility and proliferation of cancer cells in vitro

Manuela Costanzo, Alessandro Romeo, Barbara Cisterna, Laura Calderan, Paolo Bernardi, Viviana Covi, Gabriele Tabaracci, Manuela Malatesta

02-04-2020

https://doi.org/10.4081/ejh.2020.3119

1507

PDF: 899

HTML: 33
Erratum - Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng

20-06-2023

https://doi.org/10.4081/ejh.2023.3794

856

PDF: 534

HTML: 25
Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study

Giada Remoli, Chiara Rita Inguscio, Federico Boschi, Gabriele Tabaracci, Manuela Malatesta, Barbara Cisterna

26-01-2026

https://doi.org/10.4081/ejh.2026.4440

1316

PDF: 265

HTML: 16
Antioxidant support to ameliorate the oxaliplatin-dependent microglial alteration: morphological and molecular study

Jacopo J.V. Branca, Donatello Carrino, Ferdinando Paternostro, Massimo Gulisano, Matteo Becatti, Lorenzo Di Cesare Mannelli, Alessandra Pacini

10-11-2021

https://doi.org/10.4081/ejh.2021.3285

1504

PDF: 818

HTML: 18
Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cells via miR-6739-5p modulation and PI3K/AKT pathway activation: a functional histocytochemical study

Zefeng Sun, Xinrong Fan, Zhenquan Liu

02-10-2025

https://doi.org/10.4081/ejh.2025.4253

429

PDF: 424

HTML: 44
Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma

Chiara Rita Inguscio, Barbara Cisterna, Maria Assunta Lacavalla, Franco Donati, Osvaldo Angelini, Gabriele Tabaracci, Manuela Malatesta

10-10-2023

https://doi.org/10.4081/ejh.2023.3879

4746

PDF: 822

HTML: 31
Low ozone concentrations promote adipogenesis in human adipose-derived adult stem cells

Manuela Costanzo, Federico Boschi, Flavia Carton, Giamaica Conti, Viviana Covi, Gabriele Tabaracci, Andrea Sbarbati, Manuela Malatesta

03-09-2018

https://doi.org/10.4081/ejh.2018.2969

2708

PDF: 859

Supplementary: 375

HTML: 47
60 | CELLULAR DYSHOMEOSTASIS AND REDOX IMBALANCE INDUCED BY CANTHARIDIN IN GLIOBLASTOMA MODELS R. Proietti, V. D’Ezio, A. Presaghi, L. Salsedo, A. Sperati, M.A. Bologna, M. Colasanti, T. Persichini | Dept. of Science, Roma Tre University, Rome, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4678

116

PDF: 41
Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou

02-12-2021

https://doi.org/10.4081/ejh.2021.3331

2667

PDF: 1544

HTML: 42
Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang

08-09-2023

https://doi.org/10.4081/ejh.2023.3742

1266

PDF: 511

HTML: 27
Cryptotanshinone alleviates DSS-induced colitis in mouse by regulating the balance of Treg/Th17 cells and M1 macrophage activation

Lin Liu, Wei Huang, Yu Wu, Guanlong Ye, Jing Zhang, Tong Shen, Changjuan Ouyang

19-02-2026

https://doi.org/10.4081/ejh.2026.4436

645

PDF: 385

HTML: 18
06 | OBESITY-INDUCED TESTICULAR DYSFUNCTION: PROTECTIVE ROLES OF THYROID HORMONES IN HIGH-FAT DIET-FED RATS M.R. Ambruosi¹, A. Biasi¹, M. Vigliotti², N. Scopigno², F. Cioffi², M. Venditti¹ | ¹Dept. Experimental Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; ²Dept. of Science and Technology, University of Sannio, Benevento, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4624

379

PDF: 53
Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu

11-05-2026

https://doi.org/10.4081/ejh.2026.4557

417

PDF: 535

Supplementary: 45

HTML: 8
Forever particles: histochemistry in the plasticene age

Beatrice Camia, Andrea Casasco, Manuela Monti

01-08-2025

https://doi.org/10.4081/ejh.2025.4226

1470

PDF: 619

HTML: 62
DNA damage and repair in differentiation of stem cells and cells of connective cell lineages: A trigger or a complication?

Nikolajs Sjakste, Una Riekstiņa

03-05-2021

https://doi.org/10.4081/ejh.2021.3236

3333

PDF: 1449

HTML: 92
Chemotherapy-induced nephrotoxicity was improved by crocin in mouse model

Qichao Yin, Hua Xiong

03-10-2022

https://doi.org/10.4081/ejh.2022.3541

1128

PDF: 704

HTML: 47
Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1407

PDF: 721

HTML: 25
Autophagic processes increase during senescence in cultured sheep neurons and astrocytes

Vittorio Farina, Gianluca Lepore, Francesca Biagi, Marcella Carcupino, Marco Zedda

03-04-2018

https://doi.org/10.4081/ejh.2018.2891

2484

PDF: 721

HTML: 29
Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao

26-07-2023

https://doi.org/10.4081/ejh.2023.3766

2216

PDF: 1397

HTML: 22
The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis

Andrea Ferrigno, Clarissa Berardo, Laura Giuseppina Di Pasqua, Marta Cagna, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti

10-11-2020

https://doi.org/10.4081/ejh.2020.3175

1945

PDF: 999

Supplementary: 203

HTML: 34
Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer

29-02-2024

https://doi.org/10.4081/ejh.2024.3977

2310

PDF: 1258

Supplementary: 119

HTML: 196
P24 | NUTRACEUTICAL-MEDIATED EFFECTS IN THE MODULATION OF INFLAMMATORY PROCESSES IN AN IN VITRO MODEL OF HUMAN ENDOMETRIAL STROMAL CELLS L. Pietrobelli¹, V.C. Divincenzo¹, L. Sileo¹, G. Scanavino¹, E. Vicini², L. Campagnolo³, V. Corsetti⁴, A.M. Tata¹ | ¹Dept. of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome, Italy; ²Dept. of SAIMAL, Section of Histology, Sapienza University of Rome, Italy; ³Dept. of Biomedicine and Prevention, University of Rome Tor Vergata, Italy; ⁴Institute of Translational Pharmacology (IFT)-CNR, Rome, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4720

58

PDF: 31
Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan

11-11-2022

https://doi.org/10.4081/ejh.2022.3563

1821

PDF: 913

Supplementary: 146

HTML: 37
circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao

22-08-2025

https://doi.org/10.4081/ejh.2025.4230

425

PDF: 340

HTML: 12
LOX-1 deficient mice show resistance to zymosan-induced arthritis

Kazuhiko Hashimoto, Yutaka Oda, Koichi Nakagawa, Terumasa Ikeda, Kazuhiro Ohtani, Masao Akagi

22-01-2018

https://doi.org/10.4081/ejh.2018.2847

2132

PDF: 915

HTML: 86
Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li

17-05-2023

https://doi.org/10.4081/ejh.2023.3612

1617

PDF: 957

Supplementary: 109

HTML: 28
Visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis

Hai-rong Fu, Xiao-shan Li, Yong-hui Zhang, Bin-bin Feng, Lian-hong Pan

07-09-2020

https://doi.org/10.4081/ejh.2020.3131

1345

PDF: 972

HTML: 18
Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra

21-06-2022

https://doi.org/10.4081/ejh.2022.3391

4038

PDF: 1962

HTML: 65
Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun

07-04-2025

https://doi.org/10.4081/ejh.2025.4182

1252

PDF: 743

HTML: 50
Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung

24-01-2014

https://doi.org/10.4081/ejh.2014.2256

3819

PDF: 970

HTML: 512
Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation

Hongkai Xiao, Jinghu Liu, Qinhong Cai, Siyu Liang, Zhitao Hu, Xiaochao Chen

13-10-2025

https://doi.org/10.4081/ejh.2025.4254

826

PDF: 438

HTML: 44
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang

21-04-2026

https://doi.org/10.4081/ejh.2026.4537

873

PDF: 577

HTML: 17
Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy

Fenqiang Qi, Yuxin Deng, Wei Huang, Yanli Cai, Kelin Hong, Shui Xiang

15-10-2024

https://doi.org/10.4081/ejh.2024.4104

2511

PDF: 658

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CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure

S. Huang, S. Guo, F. Guo, Q. Yang, X. Xiao, M. Murata, S. Ohnishi, S. Kawanishi, N. Ma

e1

14-01-2013

https://doi.org/10.4081/ejh.2013.e1

2113

PDF: 915

HTML: 895
Nuclear factor-kB and nitric oxide synthases in red blood cells: good or bad in obesity? A preliminary study

Monika Široká, Caterina Franco, Zuzana Guľašová, Zdenka Hertelyová, Vladimíra Tomečková, Luigi F. Rodella, Rita Rezzani

21-01-2020

https://doi.org/10.4081/ejh.2020.3081

1838

PDF: 884

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Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

Nan Li, Xue Fan, Lihong Liu, Yanbing Liu

27-07-2023

https://doi.org/10.4081/ejh.2023.3506

1869

PDF: 1141

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Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang

20-04-2026

https://doi.org/10.4081/ejh.2026.4548

625

PDF: 379

Raw data: 52

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Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway

Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Han

17-09-2024

https://doi.org/10.4081/ejh.2024.4093

2397

PDF: 641

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An immunohistochemical study of the pancreatic endocrine cells of the Korean golden frog, Rana plancyi chosenica

H.S. Lee, J.H. Chang, S.K. Ku

e5

20-01-2012

https://doi.org/10.4081/ejh.2012.e5

1498

PDF: 554

HTML: 1664
LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway

Yong Jiang, Chun-hui Xu, Ying Zhao, Yun-han Ji, Xin-tao Wang, Ying Liu

16-01-2023

https://doi.org/10.4081/ejh.2023.3526

1975

PDF: 873

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Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng

17-06-2025

https://doi.org/10.4081/ejh.2025.4218

1639

PDF: 629

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Bradykinin and noradrenaline preconditioning influences level of antioxidant enzymes SOD, CuZn-SOD, Mn-SOD and catalase in the white matter of spinal cord in rabbits after ischemia/reperfusion

Marianna Danková, Iveta Domoráková, Zuzana Fagová, Milan Stebnický, Alexandra Kunová, Eva Mechírová

18-10-2019

https://doi.org/10.4081/ejh.2019.3045

1692

PDF: 751

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Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai

14-10-2022

https://doi.org/10.4081/ejh.2022.3510

1368

PDF: 706

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