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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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1.9
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3.7
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  • Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

    Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3412
    2504
    PDF: 1422
    HTML: 33
  • circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

    Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao
    22-08-2025
    https://doi.org/10.4081/ejh.2025.4230
    383
    PDF: 303
    HTML: 8
  • Calcium-induced alteration of mitochondrial morphology and mitochondrial-endoplasmic reticulum contacts in rat brown adipocytes

    I. Golic, K. Velickovic, M. Markelic, A. Stancic, A. Jankovic, M. Vucetic, V. Otasevic, B. Buzadzic, B. Korac, A. Korac
    09-09-2014
    https://doi.org/10.4081/ejh.2014.2377
    3429
    PDF: 1154
    HTML: 1547
  • Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation

    Yuejuan Cao, Li Cui, Shaoyong Tuo, Hongze Liu, Shaonan Cui
    24-04-2024
    https://doi.org/10.4081/ejh.2024.4004
    1926
    PDF: 513
    HTML: 24
  • Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

    M. Costanzo, B. Cisterna, A. Vella, T. Cestari, V. Covi, G. Tabaracci, M. Malatesta
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2515
    3084
    PDF: 1015
    HTML: 413
  • LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

    Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu
    31-05-2023
    https://doi.org/10.4081/ejh.2023.3535
    1163
    PDF: 651
    HTML: 35
  • Marine bisindole alkaloid: A potential apoptotic inducer in human cancer cells

    Sara Salucci, Sabrina Burattini, Francesca Buontempo, Ester Orsini, Lucia Furiassi, Michele Mari, Simone Lucarini, Alberto M. Martelli, Elisabetta Falcieri
    10-04-2018
    https://doi.org/10.4081/ejh.2018.2881
    2870
    PDF: 963
    HTML: 60
  • PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage

    J. Suchánková, S. Legartová, P. Sehnalová, S. Kozubek, S. Valente, D. Labella, A. Mai, C. Eckerich, F.O. Fackelmayer, D.V. Sorokin, E. Bartova
    02-05-2014
    https://doi.org/10.4081/ejh.2014.2389
    3089
    PDF: 761
    Supplementary: 319
    HTML: 814
  • Dynamic of lipid droplets and gene expression in response to β-aminoisobutyric acid treatment on 3T3-L1 cells

    Monica Colitti, Federico Boschi, Tommaso Montanari
    28-11-2018
    https://doi.org/10.4081/ejh.2018.2984
    1772
    PDF: 1093
    HTML: 51
  • Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

    A.C. Croce, G. Bottiroli
    12-12-2014
    https://doi.org/10.4081/ejh.2014.2461
    14269
    PDF: 6004
    HTML: 7973
  • The role of miRNA-29b1 on the hypoxia-induced apoptosis in mammalian cardiomyocytes

    Bo Dai, Hailin Liu, Dingmin Juan, Kaize Wu, Ruhao Cao
    27-06-2024
    https://doi.org/10.4081/ejh.2024.4021
    1040
    PDF: 499
    HTML: 31
  • MITOCHONDRIAL DYSFUNCTION AS A KEY FACTOR OF MOTOR NEURON DEGENERATION: INSIGHTS FROM AMYOTROPHIC LATERAL SCLEROSIS CELLULAR MODELS Scimia N¹, Carletti RM², Rasà MD¹, Ferrari D3, Boido M¹ and Stanga S¹ | ¹Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; ²Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; 3Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4512
    253
  • Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro

    Chiara Rita Inguscio, Flavia Carton, Barbara Cisterna, Manuela Rizzi, Francesca Boccafoschi, Gabriele Tabaracci, Manuela Malatesta
    09-09-2024
    https://doi.org/10.4081/ejh.2024.4106
    1730
    PDF: 304
    HTML: 14
  • Functional topography of the fully grown human oocyte

    Manuela Monti, Alberto Calligaro, Barry Behr, Renee Rejo Pera, Carlo Alberto Redi, Mark Wossidlo
    06-02-2017
    https://doi.org/10.4081/ejh.2017.2769
    2093
    PDF: 873
    HTML: 264
  • Ozone at low concentrations does not affect motility and proliferation of cancer cells in vitro

    Manuela Costanzo, Alessandro Romeo, Barbara Cisterna, Laura Calderan, Paolo Bernardi, Viviana Covi, Gabriele Tabaracci, Manuela Malatesta
    02-04-2020
    https://doi.org/10.4081/ejh.2020.3119
    1434
    PDF: 872
    HTML: 31
  • P80 | MITOCHONDRIA-LYSOSOME INTERACTIONS: EMERGING PLAYERS IN GLIOMA L. Zeppa1, M.B. Morelli2, C. Aguzzi2, M. Giangrossi2, M. Nabissi2, G. Cameli2, G. Santoni2, S.K. Tayebati2, V. Bellitto1, D. Tomassoni1, C. Amantini1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Pharmacy, University of Camerino, Camerino, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4406
    313
  • 06 | OBESITY-INDUCED TESTICULAR DYSFUNCTION: PROTECTIVE ROLES OF THYROID HORMONES IN HIGH-FAT DIET-FED RATS M.R. Ambruosi1, A. Biasi1, M. Vigliotti2, N. Scopigno2, F. Cioffi2, M. Venditti1 | 1Dept. Experimental Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; 2Dept. of Science and Technology, University of Sannio, Benevento, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4624
    36
    PDF: 7
  • Apoptosis activation in human carious dentin. An immunohistochemical study

    C. Loreto, A. Psaila, G. Musumeci, S. Castorina, R. Leonardi
    09-07-2015
    https://doi.org/10.4081/ejh.2015.2513
    2072
    PDF: 684
    HTML: 957
  • Cytoplasmic lattices are not linked to mouse 2-cell embryos developmental arrest

    Marianna Longo, Michele Boiani, CarloAlberto Redi, Manuela Monti
    24-09-2018
    https://doi.org/10.4081/ejh.2018.2972
    2515
    PDF: 950
    HTML: 39
  • Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability

    Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3352
    1762
    PDF: 783
    HTML: 34
  • Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

    Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang
    21-04-2026
    https://doi.org/10.4081/ejh.2026.4537
    637
    PDF: 430
    HTML: 8
  • Histochemistry in biology and medicine: a message from the citing journals

    Carlo Pellicciari
    23-12-2015
    https://doi.org/10.4081/ejh.2015.2610
    3177
    PDF: 870
    HTML: 895
  • Ultrastructural histochemistry in biomedical research: Alive and kicking

    Manuela Malatesta
    07-11-2018
    https://doi.org/10.4081/ejh.2018.2990
    1944
    PDF: 710
    HTML: 28
  • Effects of lead pollution on Ammonia parkinsoniana (foraminifera): ultrastructural and microanalytical approaches

    F. Frontalini, D. Curzi, F.M. Giordano, J.M. Bernhard, E. Falcieri, R. Coccioni
    30-01-2015
    https://doi.org/10.4081/ejh.2015.2460
    2527
    PDF: 878
    HTML: 1120
  • Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment

    Zhao Zhang, Hongming Fan, William Richardson, Bruce Z. Gao, Tong Ye
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3812
    1968
    PDF: 1019
    Supplementary: 127
    HTML: 35
  • Is there still room for novelty, in histochemical papers?

    Carlo Pellicciari
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2758
    2831
    PDF: 720
    HTML: 281
  • By Dchordpdx - Own work, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=64427063

    Quantitative, structural and molecular changes in neuroglia of aging mammals: A review

    Ennio Pannese
    23-06-2021
    https://doi.org/10.4081/ejh.2021.3249
    1724
    PDF: 856
    HTML: 18
  • SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

    Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang
    18-05-2026
    https://doi.org/10.4081/ejh.2026.4544
    163
    PDF: 126
    Supplementary: 21
    HTML: 6
  • Maternal dietary loads of alpha-tocopherol increase synapse density and glial synaptic coverage in the hippocampus of adult offspring

    S. Salucci, P. Ambrogini, D. Lattanzi, M. Betti, P. Gobbi, C. Galati, F. Galli, R. Cuppini, A. Minelli
    02-05-2014
    https://doi.org/10.4081/ejh.2014.2355
    2147
    PDF: 934
    HTML: 465
  • Fine structural detection of calcium ions by photoconversion

    V. Poletto, V. Galimberti, G. Guerra, V. Rosti, F. Moccia, M. Biggiogera
    10-08-2016
    https://doi.org/10.4081/ejh.2016.2695
    1782
    PDF: 762
    Supplementary: 307
    HTML: 139
  • ON THE WAY TO A NEW MODEL OF NEURODEGENERATION? FIRST EVIDENCE OF THE EXPRESSION OF GATA1 IN THE BRAIN: CORRELATIONS WITH AGING, MITOCHONDRIAL DAMAGE AND SYNUCLEINOPATHY C. Caturano1, F. E. Bellomi1, F. Arciprete1, V. Velardi1, L. La Barbera2, M. Falchi3, M. Bacioglu4, R. Mancinelli5, M. D’Amelio2, M. Spillantini4, M. Zingariello1, G. Vivacqua1,6 | 1Laboratory of Microscopic and Ultrastructural Anatomy, Campus Biomedico University of Rome, Italy; 2Laboratory of Molecular Neuroscience - Campus Biomedico University of Rome, Italy; 3National Centre for HIV/AIDS Research, Istituto Superior di Sanità, Rome, Italy; 4Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK; 5Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy; 6Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4315
    279
  • New insights into the in situ microscopic visualization and quantification of inorganic polyphosphate stores by 4',6-diamidino-2-phenylindole (DAPI)-staining

    F.M. Gomes, I.B. Ramos, C. Wendt, W. Girard-Dias, W. De Souza, E.A. Machado, K. Miranda
    e34
    05-11-2013
    https://doi.org/10.4081/ejh.2013.e34
    4477
    PDF: 1990
    HTML: 608
  • FLVCR1a REGULATES CORTICAL INTERNEURON DEVELOPMENT AND MIGRATION IN THE EMBRYONIC CORTEX Metani L1, Zanin Venturini DI1, Abalai RE1 and Chiabrando D1 | 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center “Guido Tarone”, University of Torino, Torino, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4501
    226
  • 14 | NR2F1 MODULATES ACTIVATION DYNAMICS AND MAINTENANCE OF THE ADULT MURINE HIPPOCAMPAL NEURAL STEM CELL POOL S. Bonzano1|2, A. Lippolis1|2, S. Quaresima3, V. Manzini3, E. Dallorto1|2, E. Cacci3, P. Peretto1|2, M. Studer4, V. Licursi5, G. Lupo3, S. De Marchis1|2 | 1Dept. of Life Sciences and Systems Biology (DBIOS), Univ. of Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano (Turin), Italy; 3Dept. of Biology and Biotechnologies Charles Darwin, Sapienza Univ. of Rome, Italy; 4Univ. Côte d'Azur, CNRS, Inserm, iBV, Nice, France; 5Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), Rome, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4632
    32
    PDF: 7
  • miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

    Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li
    22-09-2025
    https://doi.org/10.4081/ejh.2025.4239
    495
    PDF: 341
    Supplementary: 57
    HTML: 20
  • Analysis of ERK3 intracellular localization: dynamic distribution during mitosis and apoptosis

    F. Aredia, M. Malatesta, P. Veneroni, M.G. Bottone
    01-12-2015
    https://doi.org/10.4081/ejh.2015.2571
    2403
    PDF: 785
    HTML: 767
  • P24 | NUTRACEUTICAL-MEDIATED EFFECTS IN THE MODULATION OF INFLAMMATORY PROCESSES IN AN IN VITRO MODEL OF HUMAN ENDOMETRIAL STROMAL CELLS L. Pietrobelli1, V.C. Divincenzo1, L. Sileo1, G. Scanavino1, E. Vicini2, L. Campagnolo3, V. Corsetti4, A.M. Tata1 | 1Dept. of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome, Italy; 2Dept. of SAIMAL, Section of Histology, Sapienza University of Rome, Italy; 3Dept. of Biomedicine and Prevention, University of Rome Tor Vergata, Italy; 4Institute of Translational Pharmacology (IFT)-CNR, Rome, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4720
    4
    PDF: 0
  • Optimization of the autophagy measurement in a human cell line and primary cells by flow cytometry

    Tonino Alonzi, Elisa Petruccioli, Valentina Vanini, Gian Maria Fimia, Delia Goletti
    26-06-2019
    https://doi.org/10.4081/ejh.2019.3044
    2108
    PDF: 1227
    Supplementary: 194
    HTML: 31
  • Investigation of seasonal changes in lipid synthesis and metabolism-related genes in the oviduct of Chinese brown frog (Rana dybowskii)

    Yankun Wang, Yuning Liu, Yawei Wang, Ao Zhang, Wenqian Xie, Haolin Zhang, Qiang Weng, Meiyu Xu
    20-12-2023
    https://doi.org/10.4081/ejh.2023.3890
    1328
    PDF: 675
    HTML: 25
  • Ultrastructural immunocytochemistry shows impairment of RNA pathways in skeletal muscle nuclei of old mice: A link to sarcopenia?

    Maria Assunta Lacavalla, Barbara Cisterna, Carlo Zancanaro, Manuela Malatesta
    24-03-2021
    https://doi.org/10.4081/ejh.2021.3229
    2073
    PDF: 727
    HTML: 19
  • Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

    Nan Li, Xue Fan, Lihong Liu, Yanbing Liu
    27-07-2023
    https://doi.org/10.4081/ejh.2023.3506
    1741
    PDF: 1072
    HTML: 25
  • TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti1, M. C. Gagliani2, G. Bellese2, M. Crippa3, A. Abbona4, M. Paccagnella4, P. Arnaldi5, M. C. Merlano6, O. Garrone7, A.M. Porcelli8, M. Matteoli1, P. Falletta9, P. Castagnola10, K. Cortese2 | 1IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; 2DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; 3Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; 4Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; 5IRCCS Ospedale Policlinico San Martino, Genova, Italy; 6Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; 7Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 8FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; 9Vita-Salute San Raffaele University, Milan, Italy; 10IRCCS Ospedale Policlinico San Martino, Genova, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4305
    308
  • Cytoskeleton - Methods and Protocols

    CarloAlberto Redi
    e12
    19-03-2010
    https://doi.org/10.4081/ejh.2010.e12
    1351
    PDF: 451
    HTML: 178
  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2250
    PDF: 1172
    Supplementary: 110
    HTML: 156
  • Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study

    Giada Remoli, Chiara Rita Inguscio, Federico Boschi, Gabriele Tabaracci, Manuela Malatesta, Barbara Cisterna
    26-01-2026
    https://doi.org/10.4081/ejh.2026.4440
    1231
    PDF: 229
    HTML: 13
  • High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

    Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos
    17-02-2022
    https://doi.org/10.4081/ejh.2022.3360
    2554
    PDF: 1006
    HTML: 43
  • Autophagic processes increase during senescence in cultured sheep neurons and astrocytes

    Vittorio Farina, Gianluca Lepore, Francesca Biagi, Marcella Carcupino, Marco Zedda
    03-04-2018
    https://doi.org/10.4081/ejh.2018.2891
    2435
    PDF: 682
    HTML: 24
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    293
    PDF: 444
    Supplementary: 36
    HTML: 5
  • Chronic cypermethrin exposure alters mouse embryonic stem cell growth kinetics, induces Phase II detoxification response and affects pluripotency and differentiation gene expression

    Paola Rebuzzini, Cinzia Civello, Edouard Nantia Akono, Lorenzo Fassina, Maurizio Zuccotti, Silvia Garagna
    17-02-2020
    https://doi.org/10.4081/ejh.2020.3084
    1530
    PDF: 1011
    Supplementary: 203
    HTML: 12
  • Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

    Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi
    22-05-2024
    https://doi.org/10.4081/ejh.2024.4033
    1212
    PDF: 521
    HTML: 19
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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