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P69 | MICROPLASTICS AND ATHEROSCLEROSIS: EVIDENCE OF MICROPLASTICS IN CAROTID ATHEROSCLEROTIC PLAQUES R. Sciarrillo1, V. Gallicchio1, A. Lallo1, F. Carrella1, D. Barbarisi2, A. Falzarano1, M. De Falco3, F. Flora2, A. Peluso2, S. Piccolo2, L. Flora2 | 1Department of Science and Technologies, University of Sannio, Italy; 2Vascular Surgery, Hospital of National Importance San Giuseppe Moscati, Italy; 3Department of Biology, University of Naples, Italy
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Expression of nestin, parvalbumin and otoferlin during cochlear development in the mouse: an immunofluorescence study
673PDF: 619Supplementary: 68HTML: 15 -
63 | EVOLUTIONARY STRATEGIES OF CARDIAC GROWTH: THE ICEFISH HEART AS A MODEL TO CONTRAST PATHOLOGICAL CELLULAR MALADAPTATION N. Romano1, R. Gaetani2, M. Gerdol3, C. Bidoli3, M. Mercola4 E. Messina2 | 1Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; 2Dept. of Molecular Medicine, Sapienza University, Rome, Italy; 3Dept. of Life Sciences, University of Trieste, Italy; 4Dept. of Medicine and Cardiovascular Institute, Stanford University, Palo Alto, CA, USA
99PDF: 42 -
P38 | THE ROLE OF SPEXIN IN COLORECTAL CANCER J. Kiezun1, J. Godlewski1, M. Kiezun2, M. Gudelska1, K. Kisielewska1, A. E. Kowalczyk1, B. E. Krazinski1 | 1Department of Anatomy and Histology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland; 2Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Poland
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VGF AS BIOMARKER OF PRE-SYMPTOMATIC PHASE OF PARKINSON’S DISEASE Manai AL1, Modi A2, Noli B1, Choudhary SM2, Ruda-Kucerova J3, Dražanová E3,4, Khairnar A2,5, Cocco C1 | 1Department of Biomedical Sciences, University of Cagliari, Monserrato, Italy; 2International Clinical Research Center, St. Anne’s University Hospital Brno, Czech Republic; 3Department of Pharmacology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; 4Institute of Scientific Instruments of the CAS, v. v. i., Brno, Czech Republic; 5Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic
364 -
ANTIBODY-TO-IMAGING PIPELINE TO MONITOR DRUG-TARGET ENGAGEMENT IN BREAST TUMORS M. Barroso | Department of Molecular and Cellular Physiology Albany Medical College, Albany NY 12208, USA
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Hormone receptor expression in human fascial tissue
4409PDF: 1817HTML: 269 -
P75 | MICROBIOTA-GUT-BRAIN AXIS IN AN AUTISM SPECTRUM DISORDER ANIMAL MODEL F. Sulas1, G. Cominelli1, G. Favero1,2, D. Pinto2,3, F. Rinaldi2,3, R. Rezzani1,2,4 | 1Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; 2Interdepartmental University Center of Research Adaption and Regeneration of Tissues and Organs (ARTO), University of Brescia, Brescia, Italy; 3Human Microbiome Advanced Project Institute, Milan, Italy; 4Italian Society for the Study of Orofacial Pain (Società Italiana Studio Dolore Orofacciale - SISDO), Brescia, Italy
358 -
Immunofluorescence characterization of innervation and nerve-immune cell interactions in mouse lymph nodes
3133PDF: 1649Supplementary: 214HTML: 26 -
Excitatory Amino Acid Transporter 5 is widely expressed in peripheral tissues
3035PDF: 802Supplementary: 251HTML: 436 -
54 | RODLET-LIKE CELLS IN THE YELLOW-LEGGED GULL (LARUS MICHAHELLIS): FIRST EXPLORATORY STUDY OF THE INTESTINAL IMMUNE SYSTEM A. Nunnari1, A. Miller2, G.P. Lombardo1, F. Grosso3, M. Aragona3, E.R. Lauriano1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; 2Department for the Promotion of Human Sciences and Quality of life, San Raffaele University, Rome, Italy; 3Department of Veterinary Sciences, University of Messina, Italy
113PDF: 59 -
PO54 | FATTY INFILTRATION AND POTENTIAL ADIPOGENIC SHIFT OF SKELETAL MUSCLE CELLS: MULTIPARAMETRIC HISTOLOGICAL ANALYSIS OF MYOSTEATOSIS L. Morello1, G. Stati1, V. Giansante1, S. Lattanzio1, P. Cerritelli1, D. Bruni1, S. Cinti2, R. Di Pietro1,3,4 | 1Department of Medicine and Aging Sciences, “G. d’ Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Experimental and Clinical Medicine, Center of Obesity, Polytechnic University of Marche, Ancona, Italy; 3StemTeCh Group, G. d’ Annunzio Foundation, “G. d’ Annunzio” University of Chieti Pescara, Chieti, Italy; 4Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA
350 -
NEUROBIOLOGY OF SUICIDE: MORPHOLOGICAL ASSESSMENT OF MICROGLIAL NETWORK IN HUMAN POST-MORTEM PREFRONTAL CORTEX Tambuzzi S1, Bertolotto N2, Massari S2, Madaschi L3, Alini M2, Brandolese D2, Ubezio MC1, Cattaneo C1 and Amadeo A2 | 1Institute of Forensic Medicine, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; 2Department of Biosciences, Università degli Studi di Milano, Milan, Italy; 3UNITECH NOLIMITS, Università degli Studi di Milano, Milan, Italy
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ON THE WAY TO A NEW MODEL OF NEURODEGENERATION? FIRST EVIDENCE OF THE EXPRESSION OF GATA1 IN THE BRAIN: CORRELATIONS WITH AGING, MITOCHONDRIAL DAMAGE AND SYNUCLEINOPATHY C. Caturano1, F. E. Bellomi1, F. Arciprete1, V. Velardi1, L. La Barbera2, M. Falchi3, M. Bacioglu4, R. Mancinelli5, M. D’Amelio2, M. Spillantini4, M. Zingariello1, G. Vivacqua1,6 | 1Laboratory of Microscopic and Ultrastructural Anatomy, Campus Biomedico University of Rome, Italy; 2Laboratory of Molecular Neuroscience - Campus Biomedico University of Rome, Italy; 3National Centre for HIV/AIDS Research, Istituto Superior di Sanità, Rome, Italy; 4Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK; 5Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy; 6Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK
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P77 | MEMBRANE SKELETAL PROTEIN, MEMBRANE PALMITOYLATED PROTEIN 6 (MPP6), IN MOUSE CEREBRAL SYNAPSES N. Terada1, Y. Saitoh2, S. Motofuji3, A. Kamijo4, T. Suzuki5, T. Yoshizawa6, T. Sakamoto7, K. Kametani8 | 1Health Science Division, Shinshu University Graduate School of Medicine, Science and Technology, Japan; 2Center for Medical Education, Teikyo University of Science, Japan; 3Division of Biosciences, Teikyo University of Science Graduate School of Science & Engineering, Japan; 4Division of Basic & Clinical Medicine, Nagano College of Nursing, Japan; 5Department of Molecular and Cellular Physiology, Shinshu University Academic Assembly Institute of Medicine, Japan; 6Division of Animal Research, Research Center for Advanced Science and Technology, Shinshu University, Japan; 7Department of Cancer Biology, Institute of Biomedical Science, Kansai Medical University, Japan; 8Health Science Division, Shinshu University Graduate School of Medicine, Science and Technology, Japan
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P58 | VITAMIN D ATTENUATES LIVER INJURY BY REDUCING APOTOSIS, PYROPTOSIS, FERROPTOSIS AND PROMOTING REGENERATION IN TYPE 2 DIABETES S. Rzeyeva1, N. Bayromava2, T. Ozbilenler1, A. Akdemir3, M. Anapalı Aykaç4, D. Aydemir5, F. Kaya Dagistanli1, T. Ulutin1, O. Uysal1, M. Ozturk6 | 1Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul, Türkiye; 2Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul, Türkiye; 3Karabuk University, Faculty of Medicine, Karabük, Türkiye; 4Ataturk University, Faculty of Medicine, Erzurum, Türkiye; 5Istanbul University, Faculty of Medicine, Istanbul, Türkiye; 6Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul Türkiye
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Morphological and ultrastructural analysis of normal, injured and osteoarthritic human knee menisci
2805PDF: 1394Supplementary: 264HTML: 58 -
EX VIVO MAPPING OF NIGRO-THALAMIC DOPAMINERGIC TERMINALS REVEALS REGIONAL SPECIALIZATION AND SYNAPTIC MARKERS IN THE HUMAN THALAMUS Cirillo G1, Montella M2, La Mantia E2, Tedesco I2, De Luca C1, Virtuoso A1, De Angelis F1, Riccio L1, Esposito F3, Cirillo M3, Franco R2 and Papa M1 | 1Division of Human Anatomy, Neuronal Networks Morphology & Systems Biology Lab, Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli, Naples, Italy; 2Division of Pathology, Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli, Naples, Italy; 3Department of Advanced Medical and Surgical Sciences, Advanced MRI Research Center, University of Campania Luigi Vanvitelli, Naples, Italy
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P23 | CALRETININ IMMUNOREACTIVE NON-TRADITIONAL LARGE NEURONS IN THE GRANULAR LAYER OF THE HUMAN CEREBELLAR CORTEX P. Flace1, M. E. Caringella2, D. Galletta3, G. Santangelo3, C. Caporusso2, M. Stolfa2, A. Cacciola4, J.J.V. Branca5, G. Agazzino2, R. Gradini6, P. Livrea7, A. Marzullo2 | 1Medical School, University of Bari ‘Aldo Moro’, Bari, Italy; 2Section of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari ‘Aldo Moro’, Italy; 3Department of Psychology, Specialization School of Neuropsychology. University of Campania ‘Luigi Vanvitelli’, Caserta, Italy; 4Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy; 5Department of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy; 6Department of Experimental Medicine, Sapienza University, Roma, Italy; 7University of Bari ‘Aldo Moro’, Bari, Italy
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P83 | INFLAMMATORY PROFILE IN SKIN, LUNG, AND KIDNEY OF A HOCL-INDUCED MURINE MODEL OF SYSTEMIC SCLEROSIS: AN IMMUNOHISTOCHEMICAL STUDY G. Vermiglio1, J. Freni1, F. Nicita1, A. Centofanti1, D. Labellarte1, E. Rizzuto1, A. Favaloro1, M. Runci Anastasi2, G.P. Anastasi1, G. Cutroneo1 | 1Department of Biomedical, Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy; 2Department of Maxillo-Facial Surgery, University of Rome, La Sapienza, Italy
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Expression of the endocannabinoid receptors in human fascial tissue
3576PDF: 1867HTML: 2367 -
Merkel cell distribution in the human eyelid
2739PDF: 629HTML: 99 -
P59 | IMMUNOHISTOCHEMISTRY ANALYSIS TO DETECT A MOLECULAR SIGNATURE IN INTERVERTEBRAL DISC DEGENERATION L. Penolazzi1, R. Nadalini1, C. Sief1, E. Lambertini2, C. Angelini3, R. Piva1 | 1Department of Neurosciences and rehabilitation, University of Ferrara, Italy; 2Laboratorio Centralizzato di ricerca preclinica, University of Ferrara, Italy; 3Department of Translational Medicine, University of Ferrara, Italy
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PURKINJE CELL INTEGRITY IS PRESERVED BY EXERCISE IN PARANEOPLASTIC CEREBELLAR DEGENERATION: EVIDENCE FROM A CANCER CACHEXIA MOUSE MODEL Zummo FP1, Saqagandomabadi V1, Barone R1, Macaluso F1, D’Amico D1, Sausa M1, Carini F1, Di Felice V1 and David S1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy
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P26 | HUMAN CYTOMEGALOVIRUS-DRIVEN ADAPTIVE NK CELLS AND MATRIX METALLOPROTEINASES EXPRESSION AS KEY ELEMENTS IN ATHEROSCLEROTIC PLAQUE DESTABILIZATION J. Freni1, M. Crescenti2, E. Bertuccio3, A. Fittipaldi1, P. Carrega2, E. Di Carlo4, G. Ferlazzo3, G. Vermiglio1, I. Bonaccorsi2 | 1Department of Biomedical, Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy: 2Department Human Pathology, «G. Barresi», University of Messina, Messina, Italy; 3Department of Experimental Medicine (DIMES), University of Genoa, Genova, Italy; 4Department of Medicine and Sciences of Aging, «G. D’Annunzio» University of Chieti-Pescara, Chieti, Italy
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