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NEUROBIOLOGY OF SUICIDE: MORPHOLOGICAL ASSESSMENT OF MICROGLIAL NETWORK IN HUMAN POST-MORTEM PREFRONTAL CORTEX Tambuzzi S1, Bertolotto N2, Massari S2, Madaschi L3, Alini M2, Brandolese D2, Ubezio MC1, Cattaneo C1 and Amadeo A2 | 1Institute of Forensic Medicine, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; 2Department of Biosciences, Università degli Studi di Milano, Milan, Italy; 3UNITECH NOLIMITS, Università degli Studi di Milano, Milan, Italy
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P41 | INVOLVEMENT OF THE DOLPHIN’S MELON IN IMMUNE FUNCTION G.P. Lombardo1, A. Miller2, L. Spiccia1, V. Natale1, F. Pellicanò1, G. Squadrito1, E. R. Lauriano1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina; 2Department of Veterinary Sciences, University of Messina, Messina, Italy
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Lorenzo Gotte (1926-1991): a pioneer of elastin
1474PDF: 700HTML: 207 -
24 | ADMINISTRATION OF BRANCHED-CHAIN AMINO ACIDS AND DI-ALANINE MITIGATES MUSCLE ATROPHY IN A MOUSE MODEL OF CANCER CACHEXIA M. Colardo1, N. Martella1, M. Varone1, D. Pensabene1, G. Caretti2, G. Bianchini3, A. Aramini3, M. Segatto1 | 1Dept. of Biosciences and Territory, University of Molise, Italy; 2Dept. of Biosciences, University of Milan, Italy; 3Research & Early Development, Dompé Farmaceutici S.p.A., L’Aquila, Italy
99PDF: 33 -
Reliable hexokinase 3 protein detection in human cell lines and primary tissue
1967PDF: 488Supplementary: 70Uncropped Western blots: 67HTML: 14 -
FROM CLOUD TO BEDSIDE C. Tacchetti1,2 | 1Medical School & S.RACE (San-Raffaele Artificial Intelligence Center);Vita-Salute University San Raffaele, Milan, Italy; 2Experimental Imaging Center, IRCCS Hospital San Raffaele, Milan, Italy
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72 | BACULUM ONTOGENY IN WILD VIETNAMESE PRIMATES REVEALED BY MICRO-CT, 3D MORPHOMETRICS, AND INTERNAL MICROARCHITECTURE F. Spani1, G. Franceschini2, M. Carosi2, T. Nadler3, M. Colasanti2 | 1Dept. of Science and Bio-Technology, Università Campus Bio-Medico di Roma, Italy; 2Dept. of Sciences, Roma Tre University, Italy; 3Three Monkeys Wildlife Conservancy, Vietnam
117PDF: 34 -
CHEMOTHERAPY-INDUCED REMODELING OF CORTICAL PYRAMIDAL NEURONS: MORPHOLOGICAL EFFECTS OF OXALIPLATIN AND PACLITAXEL Iezzi G1,2, Marmiroli P3,4, Vercelli A1,2 and Cavaletti G3,4 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi,Turin, Italy; 3University of Milano-Bicocca, Italy; 4Experimental Neurology Unit, Monza, Italy
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39 | ENVIRONMENTAL FACTORS INFLUENCE THE PROTECTIVE EFFICACY OF BRASSICA OLERACEA EXTRACTS ON INTESTINAL AND HEPATIC HOMEOSTASIS IN ZEBRAFISH R. Imperatore1, I. Šola2, E. Coccia1, R. Sciarrillo1, M. Paolucci1 | 1Dept. of Sciences and Technologies, University of Sannio, Benevento, Italy; 2Department of Biology, Faculty of Science, University of Zagreb, Croatia
105PDF: 34 -
Sox9 expression in canine epithelial skin tumors
3216PDF: 931HTML: 408 -
A PRECLINICAL STUDY ON THE MODULATION OF THE MICROBIOTA–GUT–BRAIN AXIS BY A FUNCTIONAL SNACK PROMOTING HEALTHY AGING Bellitto V1, Grasselli F1, Martinelli I2, Nittari G2, Vittadini E1, Eleuteri AM1, Tayebati SK2, Bonfili L1 and Tomassoni D1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal and Health Products Sciences, University of Camerino, Italy
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P43 | NEW INSIGHTS IN THE ACTIVATION OF FERROPTOSIS PROCESS DURING LIVER FIBROSIS R. Mancinelli1, S. Leone1, A. Casini1, R. Vaccaro1, M. Tagliafierro1, F.M. Bassi1, E. Bocci1, S. Vitale1, A. Franchitto2, L. Pannarale1, P. Onori1, E. Gaudio1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; 2Division of Health Sciences, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, Italy
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Imaging techniques in nanomedical research
2100PDF: 842HTML: 25 -
A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer
1674PDF: 807Supplementary: 225HTML: 21 -
26 | ASSESSING DEVELOPMENTAL TOXICITY OF PSYCHOACTIVE POLLUTANTS USING XENOPUS LAEVIS AS A MODEL S. Di Marino, C. Fogliano, C.M. Motta, B. Avallone, R. Carotenuto | Dept. of Biology, University of Naples Federico II, Italy
101PDF: 39 -
CONNEXIN 43 HEMICHANNELS CAN DRIVE THE GLIOBLASTOMA SPREADING Virtuoso A1, De Luca C1, Altieri R2, Milior G3, Moulard J3, Huberfeld J3, Cirillo G1, Barbarisi M2, Rouach N3 and Papa M1 | 1Laboratory of Neural Network Morphology and Systems Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; 2Multidisciplinary Department of Medical, Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy; 3Interdisciplinary Research Center in Biology, College de France, CNRS, INSERM, Labex Memolife, Université PSL, Paris, France
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Expression of S100β during mouse cochlear development
1488PDF: 416Supplementary: 82HTML: 9 -
Immunohistochemical localization of periostin in human gingiva
2254PDF: 820HTML: 499 -
62 | APPLICATION OF AN AI-BASED WORKFLOW FOR THE ASSESSMENT OF TESTICULAR DAMAGE IN DOGS Lorenzo Riccio1|2, Maria De Falco2, Nicola Ambrosio3, Angelo Spada3, Francesca Del Porto2, Cristina Marchetti2, Orlando Paciello1, Luigi Rosati2 | 1Dept. of Veterinary Medicine and Animal Productions, University of Naples Federico II, Italy; 2Dept. of Biology, University of Naples Federico II, Italy; 3ASL Napoli 2 Nord, Italy
61PDF: 35 -
BEYOND THE SPINAL CORD: MORPHOLOGICAL ALTERATIONS OF CORTICAL PROJECTION NEURON IN SPINAL MUSCULAR ATROPHY La Rocca F1,2, Schellino R1,2, Iezzi G1,2, Caretto A1,2, Boido B1,2 and Vercelli A1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri, Ottolenghi, University of Turin, Turin, Italy
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Immunofluorescence characterization of innervation and nerve-immune cell interactions in mouse lymph nodes
2841PDF: 1630Supplementary: 205HTML: 24 -
EX VIVO MAPPING OF NIGRO-THALAMIC DOPAMINERGIC TERMINALS REVEALS REGIONAL SPECIALIZATION AND SYNAPTIC MARKERS IN THE HUMAN THALAMUS Cirillo G1, Montella M2, La Mantia E2, Tedesco I2, De Luca C1, Virtuoso A1, De Angelis F1, Riccio L1, Esposito F3, Cirillo M3, Franco R2 and Papa M1 | 1Division of Human Anatomy, Neuronal Networks Morphology & Systems Biology Lab, Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli, Naples, Italy; 2Division of Pathology, Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli, Naples, Italy; 3Department of Advanced Medical and Surgical Sciences, Advanced MRI Research Center, University of Campania Luigi Vanvitelli, Naples, Italy
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P48 | NEW STRATEGIES TO IMPROVE THE RESPONSE OF AML CELLS TO TARGETED THERAPIES BY OVERCOMING THE PROTECTIVE EFFECT OF THE BONE MARROW MESENCHYMAL STEM CELLS G. Mazzanti1, F. Liccardo2, L. Pace1, M. Marcotulli3, L. Lafrate3, G. Cidonio3, T. Ottone4, S. Travaglini4, M.T. Voso4, V. Fulci5, M. Sampaolesi1, F. Fazi1, S. Masciarelli1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences and Medical Embryology, Section of Histology Sapienza University of Rome, Rome, Italy; 2Centre de Recherches en Cancérologie de Toulouse, Inserm/ U1037, Université de Toulouse, Toulouse, France; 3Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, Rome, Italy; 4Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy; 5Department of Molecular Medicine, Sapienza, University of Rome, Rome, Italy
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28 | 3D MORPHO-FUNCTIONAL RECONSTRUCTION OF THE PREPUBERTAL MOUSE OVARY COMBINING NANO-COMPUTED TOMOGRAPHY AND CONFOCAL IMAGING A. Fantinato1|4, G. Fiorentino1|4, A. Parrilli2, G. Brazzale1, V. Merico1, P. Rebuzzini1, D. Cimadomo1|3, S. Garagna1, M. Zuccotti1 | 1Dept. of Biology and Biotechnology, University of Pavia, Italy; 2Empa-Swiss Federal Laboratories for Materials Science and Technology, Switzerland; 3IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Italy; 4Equal contribution
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AN INDUCED PLURIPOTENT STEM CELL MODEL OF FLVCR1-RELATED NEUROPATHY UNCOVERS MITOCHONDRIAL AND MEMBRANE DISORGANIZATION IN SENSORY NEURONS Zanin Venturini DI1, Kopecka J2, Zhao B3, Yu TW3, Abalai RE1, Metani L1, Salio C4, Riganti C2, Tolosano E1 and Chiabrando D1 | 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center (MBC) “Guido Tarone”, University of Torino, Turin, Italy; 2Department of Oncology, Molecular Biotechnology Center, University of Turin, Italy; 3Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, Harvard Medical School, USA; 4Department of Veterinary Sciences, University of Torino, Turin, Italy
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SUMOYLATION AS AN EARLY ADAPTIVE MECHANISM IN THE PROTEOMIC RESPONSE OF HUMAN GERM CELLS TO SIMULATED MICROGRAVITY A. Di Pauli1, G. Ricci2, M. Crescenzi3, M. A. Mariggiò4, C. Morabito4, L. Gesualdi1, M. Berardini1, F. Ferranti5, M. Signore6, A. Catizone1 | 1Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, Section of Histology and Embryology, «Sapienza» University, Rome, Italy; 2Department of Experimental Medicine, University «Luigi Vanvitelli», Naples, Italy; 3Core Facilities, Italian National Institute of Health, Rome, Italy; 4Department of Neuroscience, Imaging and Clinical Sciences CAST, «G. d’Annunzio» University, Chieti, Italy; 5Human Spaceflight and Scientific Research Unit, Italian Space Agency, Rome, Italy; 6RPPA unit, Proteomics, Italian National Institute of Health, Rome, Italy
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P06 | MODELING THE COMPLEXITY OF THE CENTRAL NERVOUS SYSTEM WITH PATIENT IPSC-DERIVED CEREBRAL ORGANOIDS L. Carpinelli1, D. Sibilia1, P.N. Doronzio2, F. Giacalone1, C. Lisciandrello2, E. Guadagni2, A. Conte3, S. Lattante4, M. Magatti5, A. Silini5, Facility Biobanca6, Facility Citometria a Flusso6, L. Di Pietro1|2, M. Sabatelli3, O. Parolini1|2 | 1Fondazione Policlinico Universitario A. Gemelli IRCSS, Rome, Italy; 2Dipartimento di Scienze della Vita e Sanità Pubblica, Università Cattolica del Sacro Cuore, Rome, Italy; 3Centro Clinico NEMO, Fondazione Policlinico Gemelli IRCCS, Rome, Italy; 4Department of Experimental Medicine, University of Salento, Lecce, Italy; 5Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 6Gemelli Science and Technology Park (GSTeP), Fondazione Policlinico Universitario A. Gemelli IRCSS, Rome, Italy
47PDF: 21 -
Paul Nakane Prize Lecture | FROM NUCLEOLAR MORPHOLOGY TO MOLECULAR REGULATION OF GENE EXPRESSION BY PHASE SEPARATION P. Hozák | Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic
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UNRAVELING GLIAL REMODELING IN SPACE AND TIME DURING GLIOBLASTOMA EVOLUTION Riccio L1, De Luca C1, Rega C1, Papa M1 and Virtuoso A1 | 1Laboratory of Neuronal Networks Morphology and System Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy
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P75 | MICROBIOTA-GUT-BRAIN AXIS IN AN AUTISM SPECTRUM DISORDER ANIMAL MODEL F. Sulas1, G. Cominelli1, G. Favero1,2, D. Pinto2,3, F. Rinaldi2,3, R. Rezzani1,2,4 | 1Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; 2Interdepartmental University Center of Research Adaption and Regeneration of Tissues and Organs (ARTO), University of Brescia, Brescia, Italy; 3Human Microbiome Advanced Project Institute, Milan, Italy; 4Italian Society for the Study of Orofacial Pain (Società Italiana Studio Dolore Orofacciale - SISDO), Brescia, Italy
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Elastofibroma dorsi: a histochemical and immunohistochemical study
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NADPH-d activity in rat thymus after the application of retinoid acid
1499PDF: 603HTML: 1334 -
Expression of nestin, parvalbumin and otoferlin during cochlear development in the mouse: an immunofluorescence study
636PDF: 576Supplementary: 60HTML: 13 -
FROM PIXELS TO DIAGNOSIS: A DEEP LEARNING FRAMEWORK FOR HISTOPATHOLOGICAL IMAGE ANALYSIS IN CANINE TESTICULAR PATHOLOGY L. Riccio1, E. Formisano2, M. De Falco3, S. Balsamo3, P. Formisano4, E. Di Napoli1, G. Piegari1, O. Paciello1, L. Rosati3 | 1Department of Veterinary Medicine and Animal Production, University of Naples “Federico II”, Naples, Italy; 2Department of Cognitive Neuroscience, Faculty of Psychology, Universiteit Maastricht, Postbus 616, The Netherlands; 3Department of Biology, University of Naples Federico II, Naples, Italy; 4Department of Translational Medicine, University Federico II, Naples, Italy
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P17 | FROM HATCHLINGS TO JUVENILES: HISTOLOGICAL ANALYSIS OF HEMOCYTE TISSUE COLONIZATION DURING GROWTH IN THE SNAIL POMACEA CANALICULATA C. Losi1, A. Ferri2, D. Roncuzzi2, G. Lucà2, S. Sacchi2, N. Franchi2, D. Malagoli2|3 | 1Models and Methods for Material and Environmental Sciences PhD Course, Dept. of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Italy; 2Dept. of Life Sciences, University of Modena and Reggio Emilia, Italy; 3NBFC-National Biodiversity Future Center, Palermo, Italy
87PDF: 23 -
HUMAN AMNIOTIC EPITHELIAL CELLS FOR RETINAL REGENERATION: INVESTIGATING THEIR DIFFERENTIATIVE POTENTIAL IN VITRO R. Pisu1, S. Saponara2, S. Angioni2, E. Peiretti2, S.G. Vitale2, F. Marongiu1 | 1Department of Biomedical Sciences, University of Cagliari, Cagliari; 2Department of Surgical Sciences, University of Cagliari, Cagliari, Italy
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