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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • To the ring-shaped nucleolus seen by microscopy using human lymphocytes of blood donors and chronic lymphocytic leukemia patients

    Karel Smetana, Dana Mikulenková, Josef Karban, Marek Trněný
    19-08-2024
    https://doi.org/10.4081/ejh.2024.4075
    1358
    PDF: 252
    HTML: 11
  • Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

    Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera
    20-04-2022
    https://doi.org/10.4081/ejh.2022.3409
    1689
    PDF: 892
    HTML: 25
  • Muscleblind-like1 undergoes ectopic relocation in the nuclei of skeletal muscles in myotonic dystrophy and sarcopenia

    M. Malatesta, M. Giagnacovo, M. Costanzo, B. Cisterna, R. Cardani, G. Meola
    e15
    22-04-2013
    https://doi.org/10.4081/ejh.2013.e15
    2860
    PDF: 4285
    HTML: 464
  • Discrete foci containing RNAse A are found in nucleoli of HeLa cells after aging in culture

    M. Costanzo, B. Cisterna, O. O. Zharskaya, O. V. Zatsepina, M. Biggiogera
    e15
    13-04-2011
    https://doi.org/10.4081/ejh.2011.e15
    1500
    PDF: 474
    HTML: 976
  • RNA/MBNL1-containing foci in myoblast nuclei from patients affected by myotonic dystrophy type 2: an immunocytochemical study

    F. Perdoni, M. Malatesta, R. Cardani, M. Giagnacovo, E. Mancinelli, G. Meola, C. Pellicciari
    e18
    23-09-2009
    https://doi.org/10.4081/ejh.2009.e18
    1647
    PDF: 903
  • Chromatin structure in situ: the contribution of DNA ultrastructural cytochemistry

    M. Derenzini, A. L. Olins, D. E. Olins
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2307
    3530
    PDF: 1082
    Supplementary: 272
    HTML: 932
  • Structural and functional alterations of the cell nucleus in skeletal muscle wasting: the evidence in situ

    M. Malatesta, G. Meola
    e44
    19-10-2010
    https://doi.org/10.4081/ejh.2010.e44
    1457
    PDF: 582
    HTML: 598
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1276
    PDF: 201
    HTML: 19
  • The Bromodomain testis-specific gene (Brdt) characterization and expression in gilthead seabream, Sparus aurata, and European seabass, Dicentrarchus labrax

    M. Úbeda-Manzanaro, J.B. Ortiz-Delgado, C. Sarasquete
    02-05-2016
    https://doi.org/10.4081/ejh.2016.2638
    1648
    PDF: 796
    HTML: 333
  • Cultured myoblasts from patients affected by myotonic dystrophy type 2 exhibit senescence-related features: ultrastructural evidence

    M. Malatesta, M. Giagnacovo, L.V. Renna, R. Cardani, G. Meola, C. Pellicciari
    e26
    21-09-2011
    https://doi.org/10.4081/ejh.2011.e26
    2079
    PDF: 735
  • Investigation of seasonal changes in lipid synthesis and metabolism-related genes in the oviduct of Chinese brown frog (Rana dybowskii)

    Yankun Wang, Yuning Liu, Yawei Wang, Ao Zhang, Wenqian Xie, Haolin Zhang, Qiang Weng, Meiyu Xu
    20-12-2023
    https://doi.org/10.4081/ejh.2023.3890
    1176
    PDF: 619
    HTML: 21
  • Premature senescence in primary muscle cultures of myotonic dystrophy type 2 is not associated with p16 induction

    L.V. Renna, R. Cardani, A. Botta, G. Rossi, B. Fossati, E. Costa, G. Meola
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2444
    2352
    PDF: 1020
    HTML: 479
  • Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cells via miR-6739-5p modulation and PI3K/AKT pathway activation: a functional histocytochemical study

    Zefeng Sun, Xinrong Fan, Zhenquan Liu
    02-10-2025
    https://doi.org/10.4081/ejh.2025.4253
    332
    PDF: 285
    HTML: 33
  • SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

    Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu
    03-03-2026
    https://doi.org/10.4081/ejh.2026.4530
    364
    PDF: 277
    HTML: 4
  • Immunofluorescent localization of ubiquitin and proteasomes in nucleolar vacuoles of soybean root meristematic cells

    D. Stępiński
    e13
    30-05-2012
    https://doi.org/10.4081/ejh.2012.13
    1091
    PDF: 441
    HTML: 1755
  • Nuclei of aged myofibres undergo structural and functional changes suggesting impairment in RNA processing

    M Malatesta, F Perdoni, S Muller, C Zancanaro, C Pellicciari
    e12
    17-08-2009
    https://doi.org/10.4081/ejh.2009.e12
    1428
    PDF: 806
  • Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity

    Bita Moudi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Seyed-Moayed Alavian, Kamran B. Lankarani, Parisa Farrokh, Jens Randel Nyengaard
    29-01-2018
    https://doi.org/10.4081/ejh.2018.2859
    2096
    PDF: 1028
    HTML: 78
  • Nuclear damages and oxidative stress: new perspectives for laminopathies

    G. Lattanzi, S. Marmiroli, A. Facchini, N.M. Maraldi
    e45
    18-10-2012
    https://doi.org/10.4081/ejh.2012.e45
    1995
    PDF: 868
    HTML: 200
  • Routinely frozen biopsies of human skeletal muscle are suitable for morphological and immunocytochemical analyses at transmission electron microscopy

    M. Giagnacovo, R. Cardani, G. Meola, C. Pellicciari, M. Malatesta
    e31
    08-07-2010
    https://doi.org/10.4081/ejh.2010.e31
    1516
    PDF: 760
    HTML: 9355
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    2869
    PDF: 1133
    Supplementary: 363
    HTML: 1013
  • Transgenic expression of dentin phosphoprotein inhibits skeletal development

    H. Zhang, P. Liu, S. Wang, C. Liu, P. Jani, Y. Lu, C. Qin
    11-03-2016
    https://doi.org/10.4081/ejh.2016.2587
    1722
    PDF: 655
    HTML: 600
  • Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

    C. Pellicciari
    e51
    16-12-2010
    https://doi.org/10.4081/ejh.2010.e51
    1426
    PDF: 711
    HTML: 3881
  • Muc5ac mucin expression during rat skin development

    V. Ferretti, Á. Segal-Eiras, C.G. Barbeito, M.V. Croce
    20-02-2015
    https://doi.org/10.4081/ejh.2015.2462
    2411
    PDF: 804
    HTML: 717
  • An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage

    K. Fujikawa, T. Yokohama-Tamaki, T. Morita, O. Baba, C. Qin, S. Shibata
    25-09-2015
    https://doi.org/10.4081/ejh.2015.2553
    1520
    PDF: 807
    HTML: 536
  • Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

    Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du
    05-05-2025
    https://doi.org/10.4081/ejh.2025.4178
    784
    PDF: 337
    Supplementary: 29
    HTML: 42
  • How to stain nucleic acids and proteins in Miller spreads

    Lorena Zannino, Marco Biggiogera
    25-02-2022
    https://doi.org/10.4081/ejh.2022.3364
    1976
    PDF: 508
    HTML: 49
  • Effect of interleukin-1beta and dehydroepiandrosterone on the expression of lumican and fibromodulin in fibroblast-like synovial cells of the human temporomandibular joint

    K. Okamoto, N. Kiga, Y. Shinohara, I. Tojyo, S. Fujita
    23-02-2015
    https://doi.org/10.4081/ejh.2015.2440
    2371
    PDF: 1085
    HTML: 588
  • MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9

    Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3275
    1857
    PDF: 768
    Supplementary: 135
    HTML: 33
  • Striatal topographical organization: Bridging the gap between molecules, connectivity and behavior

    Gianpaolo Antonio Basile, Salvatore Bertino, Alessia Bramanti, Rosella Ciurleo, Giuseppe Pio Anastasi, Demetrio Milardi, Alberto Cacciola
    13-10-2021
    https://doi.org/10.4081/ejh.2021.3284
    2544
    PDF: 1236
    HTML: 26
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3325
    PDF: 842
    HTML: 408
  • Expression and localization of α2A-adrenergic receptor in the rat post-natal developing cochlea

    Chaoyong Tian, Yang Yang, Yao Li, Fei Sun, Juan Qu, Dingjun Zha
    07-08-2023
    https://doi.org/10.4081/ejh.2023.3748
    959
    PDF: 666
    Supplementary: 77
    HTML: 11
  • On the nucleolar size and density in human early granulocytic progenitors, myeloblasts

    K Smetana, H Klamová, D Mikulenková, M Pluskalová, Z Hrkal
    119-124
    30-06-2009
    https://doi.org/10.4081/982
    485
    PDF: 685
  • Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

    Jun Lin, Liping Jiang, Kun Guo, Ning Feng
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3528
    1888
    PDF: 1171
    Supplementary: 114
    HTML: 33
  • Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

    Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li
    22-07-2024
    https://doi.org/10.4081/ejh.2024.4048
    1281
    PDF: 370
    HTML: 14
  • Effects of pre- and postnatal exposure to flutamide on connexin 43 expression in testes and ovaries of prepubertal pigs

    I. Kopera, M. Durlej, A. Hejmej, K. Knapczyk-Stwora, M. Duda, M. Slomczynska, M. Koziorowski, B. Bilinska
    e15
    14-04-2010
    https://doi.org/10.4081/ejh.2010.e15
    1574
    PDF: 908
    HTML: 5523
  • Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment

    Zhao Zhang, Hongming Fan, William Richardson, Bruce Z. Gao, Tong Ye
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3812
    1783
    PDF: 936
    Supplementary: 117
    HTML: 28
  • Novel monoclonal antibodies against Pdx1 reveal feedback regulation of Pdx1 protein levels

    T. Galbo, I. L Pedersen, T. Fløyel, C. H. Bang-Berthelsen, P. Serup, O. D Madsen, J. Hald
    e19
    15-04-2010
    https://doi.org/10.4081/ejh.2010.e19
    1504
    PDF: 937
    HTML: 3315
  • Substance P is overexpressed in cervical squamous cell carcinoma and promoted proliferation and invasion of cervical cancer cells in vitro

    Ying Wang, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang
    31-07-2023
    https://doi.org/10.4081/ejh.2023.3746
    916
    PDF: 432
    HTML: 10
  • The penetration of methanol into bovine cardiac and hepatic tissues is faster than ethanol and formalin

    Michelle Steicke, Guang Yang, Tam Nguyen Dinh, Matthew Dunster-Jones, Owen Sargisson, Farah Ahmady, Jonathan Golledge, Yutang Wang
    07-02-2018
    https://doi.org/10.4081/ejh.2018.2880
    1946
    PDF: 788
    Supplementary: 197
    HTML: 48
  • PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage

    J. Suchánková, S. Legartová, P. Sehnalová, S. Kozubek, S. Valente, D. Labella, A. Mai, C. Eckerich, F.O. Fackelmayer, D.V. Sorokin, E. Bartova
    02-05-2014
    https://doi.org/10.4081/ejh.2014.2389
    2998
    PDF: 726
    Supplementary: 309
    HTML: 801
  • Preferentially regulated expression of connexin 43 in the developing spiral ganglion neurons and afferent terminals in post-natal rat cochlea

    W.J. Liu, J. Yang
    11-02-2015
    https://doi.org/10.4081/ejh.2015.2464
    1859
    PDF: 1154
    HTML: 927
  • Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

    Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4533
    108
    PDF: 79
    HTML: 0
  • Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment

    R.J. Bułdak, M. Skonieczna, Ł. Bułdak, N. Matysiak, Ł. Mielańczyk, G. Wyrobiec, M. Kukla, M. Michalski, K. Żwirska-Korczala
    12-09-2014
    https://doi.org/10.4081/ejh.2014.2408
    2049
    PDF: 777
    HTML: 572
  • Effect of CDX2 on proliferation, invasion, migration, and apoptosis of duodenal cancer cells

    Jun Pan, Yi Zhao, Yu Zhang, Yuhe Zhou, Fengxuan Zhang, Yitian Chen, Xiaoyuan Chu
    24-04-2025
    https://doi.org/10.4081/ejh.2025.4203
    663
    PDF: 263
    HTML: 39
  • Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

    Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li
    17-05-2023
    https://doi.org/10.4081/ejh.2023.3612
    1257
    PDF: 873
    Supplementary: 78
    HTML: 19
  • Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability

    Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3352
    1631
    PDF: 743
    HTML: 29
  • alpha2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade

    Michael W.L. Quirino, Amanda P.B. Albuquerque, Maria F.D. de Souza, Antônio F. da Silva Filho, Mário R. Martins, Maira G. da Rocha Pitta, Michelly C. Pereira, Moacyr J.B. de Melo Rêgo
    29-09-2022
    https://doi.org/10.4081/ejh.2022.3330
    1293
    PDF: 673
    Supplementary: 120
    HTML: 28
  • Decellularized omentum as novel biologic scaffold for reconstructive surgery and regenerative medicine

    A. Porzionato, M. M. Sfriso, V. Macchi, A. Rambaldo, G. Lago, L. Lancerotto, V. Vindigni, R. De Caro
    e4
    24-01-2013
    https://doi.org/10.4081/ejh.2013.e4
    2293
    PDF: 979
    HTML: 1084
  • AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in autophagy-induced astrocytoma cells

    L. Fassina, G. Magenes, A. Inzaghi, S. Palumbo, G. Allavena, C. Miracco, L. Pirtoli, M. Biggiogera, S. Comincini
    e44
    11-10-2012
    https://doi.org/10.4081/ejh.2012.e44
    1982
    PDF: 959
    Supplementary Figures: 298
    Supplementary Table: 218
    HTML: 499
  • ACCELERATING DISCOVERY TOGETHER: A COMMUNITY APPROACH TO ANTIBODY VALIDATION AND MULTIPLEXED IMAGING A. Radtke | Leica Microsystems

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4285
    157
  • Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner

    Jana Oswald, Maximilian Büttner, Simon Jasinski-Bergner, Roland Jacobs, Philip Rosenstock, Heike Kielstein
    26-01-2018
    https://doi.org/10.4081/ejh.2018.2848
    3244
    PDF: 1159
    HTML: 106
  • Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation

    Yuejuan Cao, Li Cui, Shaoyong Tuo, Hongze Liu, Shaonan Cui
    24-04-2024
    https://doi.org/10.4081/ejh.2024.4004
    1826
    PDF: 451
    HTML: 20
  • On the future contents of a small journal of histochemistry

    C. Pellicciari
    e51
    10-12-2012
    https://doi.org/10.4081/ejh.2012.e51
    2430
    PDF: 947
    HTML: 938
  • Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

    Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
    17-04-2025
    https://doi.org/10.4081/ejh.2025.4176
    1241
    PDF: 518
    Supplementary: 84
    HTML: 43
  • In memoriam of Prof. Stan Fakan

    Marco Biggiogera, Manuela Malatesta
    06-02-2023
    https://doi.org/10.4081/ejh.2023.3668
    560
    PDF: 409
    HTML: 34
  • Immunohistochemical and ultrastructural study of the lamellae of oocytes in atretic follicles in relation to different processes of cell death

    M.L. Escobar, O.M. Echeverría, G. García, R. Ortíz, G.H. Vázquez-Nin
    12-08-2015
    https://doi.org/10.4081/ejh.2015.2535
    1829
    PDF: 652
    HTML: 905
  • P14 | THE ROLE OF CHROMATIN REORGANIZATION IN HYPOXIA ADAPTATION M. Cavallo1, C. Casali1, L. Giulini1, A. Dia1, D. Tunesi1, G. Milanesi1, G. Mazzini2, M. Biggiogera1 | 1Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, Pavia; Italy; 2Institute of Molecular Genetics, National Research Council (IGMCNR), Pavia, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4334
    161
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    2853
    PDF: 1630
    Video 1: 226
    Video 2: 268
    HTML: 24
  • Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

    D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev
    05-08-2015
    https://doi.org/10.4081/ejh.2015.2530
    2676
    PDF: 894
    HTML: 1387
  • NOP14 regulates the growth, migration, and invasion of colorectal cancer cells by modulating the NRIP1/GSK-3β/β-catenin signaling pathway

    Xuanjin Zhu, Weilu Jia, Yong Yan, Yong Huang, Bailin Wang
    02-07-2021
    https://doi.org/10.4081/ejh.2021.3246
    2680
    PDF: 726
    HTML: 36
  • Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

    Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3639
    1148
    PDF: 681
    HTML: 21
  • Upregulation of cardiac NO/NOS system during short-term hypoxia and the subsequent reoxygenation period

    A. Rus, M.L. Del Moral, F. Molina, M.A. Peinado
    e17
    17-05-2011
    https://doi.org/10.4081/ejh.2011.e17
    1122
    PDF: 501
    HTML: 1383
  • Ion channels alterations in the forebrain of high-fat diet fed rats

    Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni
    23-11-2021
    https://doi.org/10.4081/ejh.2021.3305
    2086
    PDF: 1055
    HTML: 31
  • Effects of hypophyseal or thymic allograft on thymus development in partially decerebrate chicken embryos: expression of PCNA and CD3 markers

    M. Aita, F. Benedetti, E. Carafelli, E. Caccia, N. Romano
    e37
    30-08-2010
    https://doi.org/10.4081/ejh.2010.e37
    1157
    PDF: 737
    HTML: 3915
  • Can a genetically-modified organism-containing diet influence embryo development? A preliminary study on pre-implantation mouse embryos

    B Cisterna, F Flach, L Vecchio, SML Barabino, S Battistelli, TE Martin, M Malatesta, M Biggiogera
    263-267
    17-08-2009
    https://doi.org/10.4081/1226
    1438
    PDF: 916
  • Analysis of ERK3 intracellular localization: dynamic distribution during mitosis and apoptosis

    F. Aredia, M. Malatesta, P. Veneroni, M.G. Bottone
    01-12-2015
    https://doi.org/10.4081/ejh.2015.2571
    2329
    PDF: 751
    HTML: 762
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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