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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

    J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei
    17-03-2014
    https://doi.org/10.4081/ejh.2014.2263
    3406
    PDF: 975
    HTML: 584
  • Immunolocalization of endocan during the endothelial-mesenchymal transition process

    L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez
    e13
    01-06-2011
    https://doi.org/10.4081/ejh.2011.e13
    1359
    PDF: 548
    HTML: 1339
  • Degenerative effects in rat eyes after experimental ocular hypertension

    G. Scarsella, M. Nebbioso, S. Stefanini, N. Pescosolido
    e42
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e42
    1483
    PDF: 578
    HTML: 202
  • Testicular expression of NGF, TrkA and p75 during seasonal spermatogenesis of the wild ground squirrel (Citellus dauricus Brandt)

    H. Zhang, Y. Wang, J. Zhang, L. Wang, Q. Li, X. Sheng, Y. Han, Z. Yuan, Q. Weng
    10-08-2015
    https://doi.org/10.4081/ejh.2015.2522
    1551
    PDF: 795
    HTML: 493
  • pPKCα mediated-HIF-1α activation related to the morphological modifications occurring in neonatal myocardial tissue in response to severe and mild hyperoxia

    S. Zara, V. Macchi, R. De Caro, M. Rapino, A. Cataldi, A. Porzionato
    e2
    31-01-2012
    https://doi.org/10.4081/ejh.2012.e2
    1681
    PDF: 2404
    HTML: 2501
  • Immunoreactivities of PPARγ2, leptin and leptin receptor in oviduct of Chinese brown frog during breeding period and pre-hibernation

    Y. Liu, J. Weng, S. Huang, Y. Shen, X. Sheng, Y. Han, M. Xu, Q. Weng
    09-09-2014
    https://doi.org/10.4081/ejh.2014.2422
    1978
    PDF: 745
    HTML: 281
  • TRAIL, DR5 and caspase 3-dependent apoptosis in vessels of diseased human temporomandibular joint disc. An immunohistochemical study

    C. Loreto, L. E. Almeida, M.R. Migliore, M. Caltabiano, R. Leonardi
    e40
    13-09-2010
    https://doi.org/10.4081/ejh.2010.e40
    2591
    PDF: 588
    HTML: 1605
  • Expression of CGRP, vasculogenesis and osteogenesis associated mRNAs in the developing mouse mandible and tibia

    Yuuki Maeda, Yoko Miwa, Iwao Sato
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2750
    2243
    PDF: 952
    HTML: 462
  • Reinke's Edema: investigations on the role of MIB-1 and hepatocyte growth factor

    M. Artico, E. Bronzetti, B. Ionta, M. Bruno, A. Greco, G. Ruoppolo, A. De Virgilio, L. Longo, M. De Vincentiis
    e30
    08-07-2010
    https://doi.org/10.4081/ejh.2010.e30
    1058
    PDF: 452
    HTML: 5984
  • Seasonal expressions of androgen receptor, estrogen receptors and cytochrome P450 aromatase in the uteri of the wild Daurian ground squirrels (Spermophilus dauricus)

    Yu Wang, Ziyi Wang, Wenyang Yu, Xia Sheng, Haolin Zhang, Yingying Han, Zhengrong Yuan, Qiang Weng
    07-02-2018
    https://doi.org/10.4081/ejh.2018.2889
    2036
    PDF: 566
    HTML: 55
  • Histochemical and morphological aspects of fresh frozen bone: a preliminary study

    F.S. De Ponte, G. Cutroneo, R. Falzea, G. Rizzo, L. Catalfamo, A. Favaloro, G. Vermiglio, M. Runci, A. Centofanti, G. Anastasi
    06-12-2016
    https://doi.org/10.4081/ejh.2016.2642
    1475
    PDF: 599
    HTML: 152
  • The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesions

    L. Pilloni, P. Bianco, E. DiFelice, S. Cabras, M.E. Castellanos, L. Atzori, C. Ferreli, P. Mulas, S. Nemolato, G. Faa
    e20
    07-06-2011
    https://doi.org/10.4081/ejh.2011.e20
    1261
    PDF: 677
    HTML: 9920
  • Effects of Notch signaling on proliferation, angiogenesis, and adipogenesis of hemangioma-derived stem cells

    Weidong Wang, Sheng Chen, Yuan Wang, Cui Jie, Weimin Shen
    01-09-2025
    https://doi.org/10.4081/ejh.2025.4241
    442
    PDF: 347
    HTML: 4
  • Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

    J. Feng, S. Ge, L. Zhang, H. Che, C. Liang
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2711
    2554
    PDF: 974
    HTML: 300
  • Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

    G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio
    e40
    04-12-2013
    https://doi.org/10.4081/ejh.2013.e40
    3641
    PDF: 969
    HTML: 626
  • Angiotensin II: immunohistochemical study in Sardinian pterygium

    P. Demurtas, M. Corrias, I. Zucca, C. Maxia, F. Piras, P. Sirigu, M.T. Perra
    28-07-2014
    https://doi.org/10.4081/ejh.2014.2426
    2103
    PDF: 731
    HTML: 362
  • The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

    Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3323
    1789
    PDF: 662
    HTML: 30
  • Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma

    Chiara Rita Inguscio, Barbara Cisterna, Maria Assunta Lacavalla, Franco Donati, Osvaldo Angelini, Gabriele Tabaracci, Manuela Malatesta
    10-10-2023
    https://doi.org/10.4081/ejh.2023.3879
    2364
    PDF: 736
    HTML: 22
  • Dipeptidylpeptidase-­IV, a key enzyme for the degradation of incretins and neuropeptides: activity and expression in the liver of lean and obese rats

    E. Tarantola, V. Bertone, G. Milanesi, E. Capelli, A. Ferrigno, D. Neri, M. Vairetti, S. Barni, I. Freitas
    e41
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e41
    1662
    PDF: 834
    HTML: 1086
  • MiR-130a-5p contributed to the progression of endothelial cell injury by regulating FAS

    Wei Wang, Wenbo Tang, Erbo Shan, Lei Zhang, Shiyuan Chen, Chaowen Yu, Yong Gao
    31-05-2022
    https://doi.org/10.4081/ejh.2022.3342
    1082
    PDF: 685
    HTML: 27
  • Secreted key regulators (Fgf1, Bmp4, Gdf3) are expressed by PAC1-immunopositive retinal ganglion cells in the postnatal rat retina

    Viktória Dénes, Kármen Kovacs, Ákos Lukáts, Adrienn Mester, Gergely Berta, Arnold Szabó, Robert Gabriel
    27-04-2022
    https://doi.org/10.4081/ejh.2022.3373
    1729
    PDF: 795
    HTML: 30
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    2887
    PDF: 1141
    Supplementary: 371
    HTML: 1013
  • Expression of the endocannabinoid receptors in human fascial tissue

    C. Fede, G. Albertin, L. Petrelli, M.M. Sfriso, C. Biz, R. De Caro, C. Stecco
    28-06-2016
    https://doi.org/10.4081/ejh.2016.2643
    3399
    PDF: 1758
    HTML: 2354
  • Elastofibroma dorsi: a histochemical and immunohistochemical study

    A. Di Vito, E. Scali, G. Ferraro, C. Mignogna, I. Presta, C. Camastra, C. Palmieri, G. Donato, T. Barni
    19-02-2015
    https://doi.org/10.4081/ejh.2015.2459
    2657
    PDF: 867
    HTML: 1097
  • Mena, a new available marker in tumors of salivary glands?

    S. Gurzu, M. Krause, I. Ember, L. Azamfirei, G. Gobel, K. Feher, I. Jung
    e8
    07-02-2012
    https://doi.org/10.4081/ejh.2012.e8
    1333
    PDF: 683
    HTML: 4120
  • Human gallbladder carcinoma: Role of neurotrophins, MIB-1, CD34 and CA15-3

    M. Artico, E. Bronzetti, V. Alicino, B. Ionta, S. Bosco, C. Grande, M. Bruno, F. M. Tranquilli Leali, G. Ionta, L. Fumagalli
    e10
    11-03-2010
    https://doi.org/10.4081/ejh.2010.e10
    1451
    PDF: 524
    HTML: 1811
  • Expressions of IL-6, TNF-α and NF-κB in the skin of Chinese brown frog (Rana dybowskii)

    Liqin Xi, Chen Wang, Pengyu Chen, Qi Yang, Ruiqi Hu, Haolin Zhang, Qiang Weng, Meiyu Xu
    19-10-2017
    https://doi.org/10.4081/ejh.2017.2834
    2341
    PDF: 852
    HTML: 63
  • Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

    Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio
    19-10-2023
    https://doi.org/10.4081/ejh.2023.3846
    1641
    PDF: 621
    HTML: 29
  • RANK/RANKL/OPG signaling pathways in necrotic jaw bone from bisphosphonate-treated subjects

    C. Di Nisio, V.L. Zizzari, S. Zara, M. Falconi, G. Teti, G. Tetè, A. Nori, V. Zavaglia, A. Cataldi
    03-02-2015
    https://doi.org/10.4081/ejh.2015.2455
    2713
    PDF: 1116
    HTML: 599
  • Assessment of proliferating cell nuclear antigen and its relationship with proinflammatory cytokines and parameters of disease activity in multiple myeloma patients

    G. Tsirakis, C. A. Pappa, M. Kaparou, V. Katsomitrou, A. Hatzivasili, T. Alegakis, A. Xekalou, E. N. Stathopoulos, M. Alexandrakis
    e21
    01-08-2011
    https://doi.org/10.4081/ejh.2011.e21
    1164
    PDF: 554
    HTML: 1079
  • CCL18 promotes endometriosis by increasing endometrial cell migration and neuroangiogenesis

    Yangying Peng, Shaojie Ding, Ping Xu, Xueyan Zhang, Jianzhang Wang, Tiantian Li, Liyun Liao, Xinmei Zhang
    06-08-2024
    https://doi.org/10.4081/ejh.2024.4052
    958
    PDF: 671
    HTML: 34
  • Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

    Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié
    21-08-2025
    https://doi.org/10.4081/ejh.2025.4174
    490
    PDF: 296
    HTML: 15
  • Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

    R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2547
    1799
    PDF: 1035
    HTML: 353
  • Lectin-like, oxidized low-density lipoprotein receptor-1-deficient mice show resistance to age-related knee osteoarthritis

    Kazuhiko Hashimoto, Yutaka Oda, Fumihisa Nakamura, Ryosuke Kakinoki, Masao Akagi
    14-02-2017
    https://doi.org/10.4081/ejh.2017.2762
    2913
    PDF: 926
    HTML: 243
  • Seasonal changes in the expression of PACAP, VPAC1, VPAC2, PAC1 and testicular activity in the testis of the muskrat (Ondatra zibethicus)

    Zeqi Tang, Xiaojie Yuan, Yuming Bai, Yiming Guo, Haolin Zhang, Yingying Han, Zhengrong Yuan, Qiang Weng
    02-05-2022
    https://doi.org/10.4081/ejh.2022.3398
    1012
    PDF: 679
    HTML: 73
  • Molecules involved in the sperm interaction in the human uterine tube: a histochemical and immunohistochemical approach

    David Cajas , Emanuel Guajardo, Sergio Jara-Rosales, Claudio Nuñez, Renato Vargas, Victor Carriel, Antonio Campos, Luis Milla, Pedro Orihuela, Carlos Godoy-Guzman
    13-04-2023
    https://doi.org/10.4081/ejh.2023.3513
    1232
    PDF: 680
    HTML: 39
  • Immunoreactivity and a new staining method of monocarboxylate transporter 1 located in endothelial cells of cerebral vessels of human brain in distinguishing cerebral venules from arterioles

    Yuan Cao, Dong-Hui Ao, Chao Ma, Wen-Ying Qiu, Yi-Cheng Zhu
    01-10-2021
    https://doi.org/10.4081/ejh.2021.3306
    1429
    PDF: 750
    HTML: 24
    Supplementary: 124
  • Image by <a href="https://pixabay.com/users/spotsoflight-6345617/?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=2744729">Monika Robak</a> from <a href="https://pixabay.com//?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=2744729">Pixabay</a>

    The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration

    Flavia Carton
    23-02-2023
    https://doi.org/10.4081/ejh.2023.3679
    1815
    PDF: 921
    HTML: 35
  • Genetic deletion of P-selectin prevents fibrosis development by inhibiting the neutrophil megakaryocyte emperipolesis in the Gata1low mouse model for myelofibrosis

    Francesca Arciprete, Viola Velardi, Antonio Di Virgilio, Paola Verachi, Claudio Carta, Giulia Pozzi, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello
    16-12-2025
    https://doi.org/10.4081/ejh.2025.4427
    574
    PDF: 296
    HTML: 4
  • Targeting EphA2 suppresses the proliferation, migration and invasion of endometriosis via the AMPK signaling pathway

    Chaoyi Yang, Shujun Wang, Mengru Li, Xiangli Pang, Aili Tan
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4168
    484
    PDF: 290
    HTML: 13
  • Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

    Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu
    17-11-2025
    https://doi.org/10.4081/ejh.2025.4426
    679
    PDF: 410
    HTML: 14
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    218
    PDF: 176
    HTML: 2
  • Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea

    Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong
    01-09-2023
    https://doi.org/10.4081/ejh.2023.3704
    1096
    PDF: 816
    HTML: 21
  • The anti-inflammatory effects of exercise training promote atherosclerotic plaque stabilization in apolipoprotein E knockout mice with diabetic atherosclerosis

    N.P.E. Kadoglou, P. Moustardas, A. Kapelouzou, M. Katsimpoulas, A. Giagini, E. Dede, N. Kostomitsopoulos, P.E. Karayannacos, A. Kostakis, C.D. Liapis
    e3
    25-03-2013
    https://doi.org/10.4081/ejh.2013.e3
    2405
    PDF: 905
    HTML: 739
  • Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

    Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
    17-04-2025
    https://doi.org/10.4081/ejh.2025.4176
    1255
    PDF: 533
    Supplementary: 91
    HTML: 43
  • Radioprotective potential of histamine on rat small intestine and uterus

    E. Carabajal, N. Massari, M. Croci, D. J. Martinel Lamas, J. P. Prestifilippo, R. M. Bergoc, E. S. Rivera, V. A. Medina
    e48
    18-12-2012
    https://doi.org/10.4081/ejh.2012.e48
    1266
    PDF: 701
    HTML: 910
  • Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

    C. Pellicciari
    e51
    16-12-2010
    https://doi.org/10.4081/ejh.2010.e51
    1433
    PDF: 715
    HTML: 3881
  • Is there still room for novelty, in histochemical papers?

    Carlo Pellicciari
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2758
    2727
    PDF: 700
    HTML: 279
  • MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

    Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3426
    1400
    PDF: 788
    HTML: 25
  • Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

    V.N. Karavana, H. Gakiopoulou, E.A. Lianos
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2308
    2167
    PDF: 867
    HTML: 645
  • Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats

    Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3328
    2114
    PDF: 1232
    HTML: 85
  • Alarin regulates RyR2 and SERCA2 to improve cardiac function in heart failure with preserved ejection fraction

    Jinshuang Li, Dawei Xu, Ce Shi, Chunqi Cheng, Ziheng Xu, Xingjuan Gao, Yong Cheng
    28-10-2024
    https://doi.org/10.4081/ejh.2024.4122
    1381
    PDF: 514
    HTML: 14
  • Developmental characteristics of cutaneous telocytes in late embryos of the silky fowl

    Hao Li, Junliang Chen, Wenjun You, Yizhen Xu, Yaqiong Ye, Haiquan Zhao, Junxing Li, Hui Zhang
    15-10-2024
    https://doi.org/10.4081/ejh.2024.4089
    1601
    PDF: 332
    HTML: 9
  • Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

    Rong Tian, Gengsheng Mao
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3350
    1756
    PDF: 853
    HTML: 36
  • The possible alleviating effect of garlic supplement on the neural retina in a rat model of hypercholesterolemia: a histological and immunohistochemical study

    Eetmad A. Arafat, Eman M.I. Youssef, Hanaa A. Khalaf
    16-12-2021
    https://doi.org/10.4081/ejh.2021.3322
    1177
    PDF: 516
    HTML: 21
  • Immunohistochemical study of doublecortin and nucleostemin in canine brain

    E. De Nevi, P. Marco-Salazar, D. Fondevila, E. Blasco, L. Pérez, M. Pumarola
    e9
    20-03-2013
    https://doi.org/10.4081/ejh.2013.e9
    2415
    PDF: 679
    HTML: 280
  • Mast cells in meningiomas

    Antonio D'Amati, Roberto Tamma, Tiziana Annese, Anna Rizzi, Domenico Ribatti
    18-04-2024
    https://doi.org/10.4081/ejh.2024.3973
    1377
    PDF: 413
    HTML: 24
  • Expression of S100β during mouse cochlear development

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Lizhong Su
    10-03-2025
    https://doi.org/10.4081/ejh.2025.4189
    1335
    PDF: 349
    Supplementary: 60
    HTML: 6
  • Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse

    A. Vetuschi, A. D'Alfonso, R. Sferra, D. Zanelli, S. Pompili, F. Patacchiola, E. Gaudio, G. Carta
    16-02-2016
    https://doi.org/10.4081/ejh.2016.2604
    2200
    PDF: 912
    HTML: 627
  • Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

    Nan Li, Xue Fan, Lihong Liu, Yanbing Liu
    27-07-2023
    https://doi.org/10.4081/ejh.2023.3506
    1577
    PDF: 986
    HTML: 20
  • P72 | A SWAB NEGATIVE PATIENT AFTER SARS-COV-2 INFECTION DISPLAYS INCREASE OF VEGF AND FIBRONECTIN ASSOCIATED WITH ALTERATIONS OF INTERCELLULAR JUNCTIONS C. Simioni1, J.M. Sanz2, R. Gafà3, G. Cenacchi4, S. Occhionorelli3, R. Rizzo5, D. Bortolotti5, A. Passaro3, L.M. Neri3 | 1Department of Life Sciences and Biotechnology, University of Ferrara, Italy; 2Department of Chemical, Pharmaceutical and Agricultural, Sciences, University of Ferrara, Italy; 3Department of Translational Medicine, University of Ferrara, Italy; 4Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Italy; 5Department of Environmental and Prevention Sciences, University of Ferrara, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4397
    251
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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