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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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1.9
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  • IMMUNOLOGICAL MECHANISMS IN REGENERATIVE MEDICINE: A LESSON FROM THE HUMAN PLACENTA O. Parolini1,2 | 1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy; 2Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4266
    345
  • Mammaglobin, GATA-binding protein 3 (GATA3), and epithelial growth factor receptor (EGFR) expression in different breast cancer subtypes and their clinical significance

    Xin Kong, Qi Wang, Jie Li, Ming Li, Fusheng Deng, Chuanying Li
    07-04-2022
    https://doi.org/10.4081/ejh.2022.3315
    1610
    PDF: 805
    Supplementary: 157
    HTML: 17
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    3061
    PDF: 1693
    Video 1: 242
    Video 2: 289
    HTML: 25
  • In vivo imaging techniques: a new era for histochemical analysis

    A. Busato, P. Fumene Feruglio, P.P. Parnigotto, P. Marzola, A. Sbarbati
    28-11-2016
    https://doi.org/10.4081/ejh.2016.2725
    2037
    PDF: 899
    HTML: 283
  • Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

    V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas
    e5
    08-02-2011
    https://doi.org/10.4081/ejh.2011.e5
    1439
    PDF: 792
    HTML: 3464
  • THE USE OF BIOMIMETIC 2D AND 3D UROTHELIAL IN VITRO MODELS WITH MOLECULAR, MORPHOLOGICAL AND FUNCTIONAL CHARACTERISTICS OF NORMAL AND CANCEROUS BLADDER TISSUE AS AN ALTERNATIVE METHOD IN PRECLINICAL STUDIES M.E. Kreft1, L. Tratnjek1, A. Janev1, N. Resnik1, U. Cerkvenik1, U. D. Jerman1, G. Markovič1, T.Ž. Ramuta1, T. Višnjar1, Ž. Sardoč1, A.Punčuh1, S. Kralj2, M. Čemažar3, P. Veranič1 |1Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; 2Department for Materials Synthesis, Jožef Stefan Institute, Ljubljana, Slovenia; 3Institute of Oncology Ljubljana, Ljubljana, Slovenia

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4288
    223
  • MICROFLUIDIC PLATFORM TO UNRAVEL GLIOMASECRETOME INTERACTION D’Amico AG1, Rasà DM1, Maugeri G2, Pricoco E3, Gulisano M1 and D’Agata V2 | 1Department of Drug and Health Sciences, University of Catania, Italy; 2Department of Biomedical and Biotechnological Sciences, University of Catania, Italy; 3Anatomic Pathology, A.O.U. Policlinico G. Rodolico-San Marco, Catania, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4510
    223
  • ANTIBODY-TO-IMAGING PIPELINE TO MONITOR DRUG-TARGET ENGAGEMENT IN BREAST TUMORS M. Barroso | Department of Molecular and Cellular Physiology Albany Medical College, Albany NY 12208, USA

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4270
    299
  • Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells in vitro

    Xilin Ge, Caoxin Huang, Wenting Chen, Chen Yang, Wenfang Huang, Jia Li, Shuyu Yang
    25-11-2024
    https://doi.org/10.4081/ejh.2024.4140
    2008
    PDF: 639
    HTML: 27
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2721
    PDF: 843
    HTML: 346
  • P68 | EARLY EFFECTS OF MECHANOACUSTIC FOCUSED VIBRATION (MFV) ON PRIMARY HUMAN SATELLITE CELLS ISOLATED FROM YOUNG AND OLDER INDIVIDUALS S. Sancilio1, G. Stati1, E.S. Di Filippo2, S. Fulle2, R. Di Pietro1 | 1Department of Medicine and Aging Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Neuroscience Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4393
    252
  • P83 | INFLAMMATORY PROFILE IN SKIN, LUNG, AND KIDNEY OF A HOCL-INDUCED MURINE MODEL OF SYSTEMIC SCLEROSIS: AN IMMUNOHISTOCHEMICAL STUDY G. Vermiglio1, J. Freni1, F. Nicita1, A. Centofanti1, D. Labellarte1, E. Rizzuto1, A. Favaloro1, M. Runci Anastasi2, G.P. Anastasi1, G. Cutroneo1 | 1Department of Biomedical, Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy; 2Department of Maxillo-Facial Surgery, University of Rome, La Sapienza, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4409
    284
  • The multifaceted role of podoplanin expression in hepatocellular carcinoma

    Andreea Cioca, Amalia R. Ceausu, Irina Marin, Marius Raica, Anca M. Cimpean
    13-02-2017
    https://doi.org/10.4081/ejh.2017.2707
    2538
    PDF: 850
    HTML: 320
  • MORPHOLOGICAL AND SYNAPTIC CHANGES OF THE CORTICAL GABAERGIC INHIBITORY SYSTEM IN SPINAL MUSCULAR ATROPHY Menduti G1,2, Ferrini F3,4, Caretto A1,2, Hassan A5,6, di Vito R6,7, Beltrando G1,2, Marnetto D2, Usiello A6,7, Di Cunto F1,2, Boido M1,2, and Vercelli A1,2 | 1Neuroscience Institute Cavalieri Ottolenghi, Orbassano, Turin, Italy; 2Department of Neuroscience «Rita Levi Montalcini», University of Turin, Italy; 3Department of Veterinary Sciences, University of Turin, Grugliasco, Turin, Italy; 4Department of Psychiatry and Neuroscience, Université Laval, Québec, Canada; 5European School of Molecular medicine, University of Milan, Italy; 6Laboratory of Translational Neuroscience, Ceinge Biotecnologie Avanzate, Naples, Italy; 7Department of Environmental, Biological and Pharmaceutical Science and Technologies, Università degli Studi della Campania Luigi Vanvitelli, Caserta, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4499
    221
  • Swertiamarin suppresses proliferation, migration, and invasion of hepatocellular carcinoma cells via negative regulation of FRAT1

    Shufeng Xiao, Haoren Tang, Yao Bai, Renchao Zou, Zongfang Ren, Xuesong Wu, Zhitian Shi, Song Lan, Wei Liu, Tiangen Wu, Cheng Zhang, Lin Wang
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3169
    1495
    PDF: 745
    HTML: 31
  • Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

    Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani
    25-08-2017
    https://doi.org/10.4081/ejh.2017.2826
    3083
    PDF: 1300
    HTML: 140
  • Mistletoe - From mythology to evidence-based medicine

    Manuela Monti
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2577
    1486
    PDF: 628
    HTML: 138
  • Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

    Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3653
    1221
    PDF: 632
    HTML: 39
  • The matrix stiffness is increased in the eutopic endometrium of adenomyosis patients: a study based on atomic force microscopy and histochemistry

    Xiaowen Wang, Wenbin Cai, Ting Liang, Hui Li, Yingjie Gu, Xiaojiao Wei, Hong Zhang, Xiaojun Yang
    04-12-2024
    https://doi.org/10.4081/ejh.2024.4131
    1947
    PDF: 493
    HTML: 56
  • UNRAVELING GLIAL REMODELING IN SPACE AND TIME DURING GLIOBLASTOMA EVOLUTION Riccio L1, De Luca C1, Rega C1, Papa M1 and Virtuoso A1 | 1Laboratory of Neuronal Networks Morphology and System Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4477
    271
  • ASTROCYTE DYSFUNCTION IN AUTOSOMAL DOMINANT LEUKODYSTROPHY (ADLD): INSIGHTS FROM 2D AND 3D IN VITRO SYSTEMS AND EX VIVO CEREBROSPINAL FLUID METABOLOMICS F.D. Koufi1, V. Righi2, A. Mucci3, I. Rusciano1, S. Mongiorgi1, M. Shin4, Y. Kosodo4, I. Cani5, P. Cortelli6, E. Giorgio7, G. Ramazzotti1, L. Manzoli1, S. Ratti1 | 1 Cellular Signaling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Department of Life Quality Studies, University of Bologna, Campus of Rimini, Rimini, Italy; 3Department of Geological and Chemical Sciences, University of Modena and Reggio Emilia, Modena, Italy; 4Korea Brain Research Institute (KBRI), Daegu, Republic of Korea; 5Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 6IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; 7Department of Molecular Medicine, University of Pavia, Pavia, Italy; Medical Genetics Unit, IRCCS Mondino Foundation, Pavia, Italy.

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4312
    316
  • Topographical organization of TRPV1-immunoreactive epithelium and CGRP-immunoreactive nerve terminals in rodent tongue

    M. Kawashima, K. Imura, I. Sato
    e21
    10-05-2012
    https://doi.org/10.4081/ejh.2012.21
    1672
    PDF: 588
    HTML: 5141
  • P32 | BLOCKING CANCER CELL MOVEMENT: THE ROLE OF PAXILLIN AND EZRIN IN CERVICAL TUMOR M. Hałas-Wiśniewska1, W. Arendt1, M. Gagat1,2, M. Izdebska1 | 1Department of Histology and Embryology, Nicolaus Copernicus University in Toruń, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Poland; 2Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4352
    182
  • MAGE-A3/4 and NY-ESO-1 antigens expression in metastatic esophageal squamous cell carcinoma

    T. Bujas, Z. Marusic, M. Peric Balja, A. Mijic, B. Kruslin, D. Tomas
    e7
    21-03-2011
    https://doi.org/10.4081/ejh.2011.e7
    1875
    PDF: 823
    HTML: 990
  • Elastofibroma dorsi: a histochemical and immunohistochemical study

    A. Di Vito, E. Scali, G. Ferraro, C. Mignogna, I. Presta, C. Camastra, C. Palmieri, G. Donato, T. Barni
    19-02-2015
    https://doi.org/10.4081/ejh.2015.2459
    2730
    PDF: 900
    HTML: 1097
  • Thymosin beta 4 expression in normal skin, colon mucosa and in tumor infiltrating mast cells

    S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, M. Fraschini, B. Manconi, I. Messana, M. Castagnola, G. Faa
    e3
    16-02-2010
    https://doi.org/10.4081/ejh.2010.e3
    1036
    PDF: 552
    HTML: 1427
  • P19 | LOQANT: IMAGEJ SCRIPT FOR ANALYSING NUCLEO-CYTOPLASMIC PROTEIN TRANSLOCATION K. Cizkova | Department of Histology and Embryology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4339
    223
  • High temperature requirement A1, transforming growth factor beta1, phosphoSmad2 and Ki67 in eutopic and ectopic endometrium of women with endometriosis

    G. Goteri, E. Altobelli, G. Tossetta, A. Zizzi, C. Avellini, C. Licini, T. Lorenzi, M. Castellucci, A. Ciavattini, D. Marzioni
    09-12-2015
    https://doi.org/10.4081/ejh.2015.2570
    2677
    PDF: 818
    HTML: 411
  • GENERATION AND CHARACTERIZATION OF A KNOCK-IN MOUSE MODEL FOR FLVCR1-RELATED SENSORY NEUROPATHY Abalai RE1, Marvaldi L2, Ferrini F3, Riganti C1, Zanin Venturini DI1, Metani L1, Tolosano E1 and Chiabrando D1 | 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center “Guido Tarone”, University of Torino, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Italy; 3Dipartimento di Morfofisiologia Veterinaria and Rita Levi Montalcini Center for Brain Repair, Grugliasco (TO), Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4479
    254
  • Investigation of seasonal changes in lipid synthesis and metabolism-related genes in the oviduct of Chinese brown frog (Rana dybowskii)

    Yankun Wang, Yuning Liu, Yawei Wang, Ao Zhang, Wenqian Xie, Haolin Zhang, Qiang Weng, Meiyu Xu
    20-12-2023
    https://doi.org/10.4081/ejh.2023.3890
    1314
    PDF: 670
    HTML: 23
  • The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

    Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3323
    1888
    PDF: 683
    HTML: 31
  • P80 | MITOCHONDRIA-LYSOSOME INTERACTIONS: EMERGING PLAYERS IN GLIOMA L. Zeppa1, M.B. Morelli2, C. Aguzzi2, M. Giangrossi2, M. Nabissi2, G. Cameli2, G. Santoni2, S.K. Tayebati2, V. Bellitto1, D. Tomassoni1, C. Amantini1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Pharmacy, University of Camerino, Camerino, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4406
    311
  • Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

    G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio
    e40
    04-12-2013
    https://doi.org/10.4081/ejh.2013.e40
    3749
    PDF: 1007
    HTML: 630
  • P64 | EX VIVO EXTRACTION OF GLIOMA SECRETOME: A NOVEL MICROENVIRONMENT-BASED PROTOCOL FOR METABOLIC AND MOLECULAR PROFILING I. Neri1, M.V. Marvi1, V. Righi2, V. Papa3, E. Boschetti1, S. Blando1, E. Franceschi4, M. Zoli4, D. Mazzatenta4, N. Neri4, A. Vignaroli4, L. Cocco1, L. Manzoli1, S. Ratti1 | 1Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Department of Life Quality Sciences, University of Bologna, Bologna, Italy; 3IRCCS St. Orsola, Bologna, Italy; 4IRCCS Institute of Neurological Sciences of Bologna, Bologna, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4389
    318
  • Three-dimensional apoptotic nuclear behavior analyzed by means of Field Emission in Lens Scanning Electron Microscope

    S. Salucci, S. Burattini, E. Falcieri, P. Gobbi
    15-09-2015
    https://doi.org/10.4081/ejh.2015.2539
    1602
    PDF: 956
    HTML: 374
  • HUMAN INDUCED PLURIPOTENT STEM CELLS-DERIVED CEREBRAL ORGANOIDS AS A MODEL FOR C9ORF72-LINKED FRONTO-TEMPORAL DEMENTIA: INSIGHTS INTO NEURONAL AND GLIAL DIFFERENTIATION DYNAMICS Ferrero C1,2,3, Pacca P1,2, Vercelli A1,2 and Boido M1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Italy 3University School for Advanced Studies IUSS Pavia, Pavia, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4489
    252
  • SerpinB3 administration protects liver against ischemia-reperfusion injury

    Cristian Turato, Mariapia Vairetti, Marta Cagna, Alessandra Biasiolo, Andrea Ferrigno, Santina Quarta, Mariagrazia Ruvoletto, Silvia De Siervi, Patrizia Pontisso, Laura Giuseppina Di Pasqua
    28-10-2022
    https://doi.org/10.4081/ejh.2022.3561
    1320
    PDF: 761
    HTML: 34
  • Incubation under fluid dynamic conditions markedly improves the structural preservation in vitro of explanted skeletal muscles

    Flavia Carton, Laura Calderan, Manuela Malatesta
    28-11-2017
    https://doi.org/10.4081/ejh.2017.2862
    1621
    PDF: 613
    HTML: 112
  • Maturation of neurotransmission in the developing rat cochlea: immunohistochemical evidence from differential expression of synaptophysin and synaptobrevin 2

    S. He, J. Yang
    e2
    18-01-2011
    https://doi.org/10.4081/ejh.2011.e2
    1291
    PDF: 562
    HTML: 2068
  • From the intestinal mucosal barrier to the enteric neuromuscular compartment: an integrated overview on the morphological changes in Parkinson’s disease

    Carolina Pellegrini, Vanessa D'Antongiovanni, Chiara Ippolito, Cristina Segnani, Luca Antonioli, Matteo Fornai, Nunzia Bernardini
    22-11-2021
    https://doi.org/10.4081/ejh.2021.3278
    1531
    PDF: 847
    HTML: 40
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European Journal of Histochemistry

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