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  Long non-coding RNA WAC antisense RNA 1 mediates hepatitis B virus replication in vitro by reinforcing miR-192-5p/ATG7-induced autophagy

  Minkai Cao, Deping Yuan, Hongxiu Jiang, Guanlun Zhou, Chao Chen, Guorong Han

  02-09-2022

  https://doi.org/10.4081/ejh.2022.3438

  1493

  PDF: 904

  HTML: 44
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  LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

  Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu

  31-05-2023

  https://doi.org/10.4081/ejh.2023.3535

  1135

  PDF: 635

  HTML: 33
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  Effects of the lncRNA ENST00000623984 on colon cancer and the biological characteristics of colon cancer cells

  Zhi-bao Liu, Jing-hua Zhang, Jing-hua Gao, Jian Shi

  12-07-2021

  https://doi.org/10.4081/ejh.2021.3215

  2182

  PDF: 565

  HTML: 29
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  The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

  Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li

  25-11-2021

  https://doi.org/10.4081/ejh.2021.3323

  1869

  PDF: 679

  HTML: 31
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  Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

  Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li

  25-10-2022

  https://doi.org/10.4081/ejh.2022.3529

  1717

  PDF: 809

  HTML: 36
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  LncRNA FBXO18-AS promotes gastric cancer progression by TGF-β1/Smad signaling

  Yiming Zhang, Wanqiong Zheng, Liang Zhang, Yechun Gu, Lihe Zhu, Yingpeng Huang

  20-06-2023

  https://doi.org/10.4081/ejh.2023.3667

  1192

  PDF: 638

  Supplementary: 93

  HTML: 22
• 

  LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma

  Nuobei Zhang, Hao Shen, Shenan Huang, Fenfen Wang, Huifang Liu, Fen Xie, Lei Jiang, Xin Chen

  16-11-2021

  https://doi.org/10.4081/ejh.2021.3300

  1278

  PDF: 657

  HTML: 49
• 

  Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

  Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai

  14-10-2022

  https://doi.org/10.4081/ejh.2022.3510

  1293

  PDF: 673

  HTML: 36
• 

  LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway

  Yong Jiang, Chun-hui Xu, Ying Zhao, Yun-han Ji, Xin-tao Wang, Ying Liu

  16-01-2023

  https://doi.org/10.4081/ejh.2023.3526

  1738

  PDF: 805

  HTML: 59
• 

  Long noncoding RNA H19 accelerates tenogenic differentiation by modulating miR-140-5p/VEGFA signaling

  You-Jie Liu, Hua-Jun Wang, Zhao-Wen Xue, Lek-Hang Cheang, Man-Seng Tam, Ri-Wang Li, Jie-Ruo Li, Hui-Ge Hou, Xiao-Fei Zheng

  07-09-2021

  https://doi.org/10.4081/ejh.2021.3297

  1797

  PDF: 947

  Supplementary: 164

  HTML: 25
• 

  An emerging potential therapeutic target for osteoporosis: LncRNA H19/miR-29a-3p axis

  Ziqi Li, Zhinan Hong, Yuesheng Zheng, Yongwei Dong, Wei He, Yingjia Yuan, Junbiao Guo

  06-11-2020

  https://doi.org/10.4081/ejh.2020.3155

  1574

  PDF: 735

  HTML: 11
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  Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

  Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye

  30-09-2021

  https://doi.org/10.4081/ejh.2021.3224

  3451

  PDF: 1874

  HTML: 39
• 

  Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

  Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera

  20-04-2022

  https://doi.org/10.4081/ejh.2022.3409

  1782

  PDF: 917

  HTML: 27

• Erratum - LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

  Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu

  07-05-2024

  https://doi.org/10.4081/ejh.2024.4058

  1316

  PDF: 310

  HTML: 9
• 

  miRNA-877-5p inhibits malignant progression of prostate cancer by directly targeting SSFA2

  Wanchun Wang, Jun Yi, Degang Dong, Wenli Mao, Xuanyu Wang, Zhangren Yan

  20-09-2021

  https://doi.org/10.4081/ejh.2021.3243

  1373

  PDF: 663

  HTML: 38

• Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

  Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang

  17-09-2024

  https://doi.org/10.4081/ejh.2024.4034

  1159

  PDF: 577

  HTML: 10
• 

  MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

  Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo

  21-06-2022

  https://doi.org/10.4081/ejh.2022.3426

  1461

  PDF: 818

  HTML: 25
• 

  SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

  Yiyu Qin, Jian Li, Hongchao Han, Yongliang Zheng, Haiming Lei, Yang Zhou, Hongyan Wu, Guozhe Zhang, Xiang Chen, Zhengping Chen

  28-12-2023

  https://doi.org/10.4081/ejh.2023.3899

  1090

  PDF: 322

  HTML: 7
• 

  Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

  Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du

  05-05-2025

  https://doi.org/10.4081/ejh.2025.4178

  881

  PDF: 387

  Supplementary: 49

  HTML: 48
• 

  Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability

  Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan

  07-12-2021

  https://doi.org/10.4081/ejh.2021.3352

  1738

  PDF: 771

  HTML: 30
• 

  miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

  Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan

  07-12-2021

  https://doi.org/10.4081/ejh.2021.3237

  1504

  PDF: 572

  HTML: 25
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  Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

  Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou

  22-06-2022

  https://doi.org/10.4081/ejh.2022.3394

  1961

  PDF: 1268

  HTML: 27
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  Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma

  Zhiyang Wang, Jing Li, Ziwei Liu, Ling Yue

  20-03-2023

  https://doi.org/10.4081/ejh.2023.3622

  1239

  PDF: 746

  HTML: 34
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  NOP14 regulates the growth, migration, and invasion of colorectal cancer cells by modulating the NRIP1/GSK-3β/β-catenin signaling pathway

  Xuanjin Zhu, Weilu Jia, Yong Yan, Yong Huang, Bailin Wang

  02-07-2021

  https://doi.org/10.4081/ejh.2021.3246

  2818

  PDF: 761

  HTML: 37

• P14 | THE ROLE OF CHROMATIN REORGANIZATION IN HYPOXIA ADAPTATION M. Cavallo¹, C. Casali¹, L. Giulini¹, A. Dia¹, D. Tunesi¹, G. Milanesi¹, G. Mazzini², M. Biggiogera¹ | ¹Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, Pavia; Italy; ²Institute of Molecular Genetics, National Research Council (IGMCNR), Pavia, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4334

  184
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  Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

  Nan Li, Xue Fan, Lihong Liu, Yanbing Liu

  27-07-2023

  https://doi.org/10.4081/ejh.2023.3506

  1705

  PDF: 1051

  HTML: 22
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  Phosphorylation mutation impairs the promoting effect of spastin on neurite outgrowth without affecting its microtubule severing ability

  Yunlong Zhang, Xin He, Jianyu Zou, Jie Yang, Ao Ma, Minghui Tan

  12-01-2023

  https://doi.org/10.4081/ejh.2023.3594

  1460

  PDF: 778

  HTML: 33
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  Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

  Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang

  01-09-2025

  https://doi.org/10.4081/ejh.2025.4217

  519

  PDF: 204

  HTML: 9
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  2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

  Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini

  19-10-2021

  https://doi.org/10.4081/ejh.2021.3276

  3047

  PDF: 1687

  Video 1: 238

  Video 2: 284

  HTML: 25
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  Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

  Jun Lin, Liping Jiang, Kun Guo, Ning Feng

  22-12-2022

  https://doi.org/10.4081/ejh.2023.3528

  1992

  PDF: 1213

  Supplementary: 129

  HTML: 37
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  circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

  Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao

  22-08-2025

  https://doi.org/10.4081/ejh.2025.4230

  368

  PDF: 286

  HTML: 5
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  microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

  Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu

  10-05-2022

  https://doi.org/10.4081/ejh.2022.3333

  1754

  PDF: 904

  HTML: 28
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  Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

  Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang

  07-12-2023

  https://doi.org/10.4081/ejh.2023.3816

  1190

  PDF: 688

  HTML: 35
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  Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

  Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan

  11-11-2022

  https://doi.org/10.4081/ejh.2022.3563

  1625

  PDF: 862

  Supplementary: 121

  HTML: 33
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  Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

  Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

  06-08-2025

  https://doi.org/10.4081/ejh.2025.4228

  1153

  PDF: 520

  HTML: 18
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  High glucose inhibits neural differentiation by excessive autophagy via peroxisome proliferator-activated receptor gamma

  Yin Pan, Di Qiu, Shu Chen, Xiaoxue Han, Ruiman Li

  11-05-2023

  https://doi.org/10.4081/ejh.2023.3691

  1279

  PDF: 883

  HTML: 21
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  Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

  Jiapei Lv, Wang Yanting, Shan Wei

  08-11-2023

  https://doi.org/10.4081/ejh.2023.3867

  2007

  PDF: 975

  HTML: 49
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  miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

  Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi

  23-09-2025

  https://doi.org/10.4081/ejh.2025.4238

  425

  PDF: 318

  HTML: 11
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  miR-19a targeting CLCA4 to regulate the proliferation, migration, and invasion of colorectal cancer cells

  Huiwen Li, Bo Huang

  10-03-2022

  https://doi.org/10.4081/ejh.2022.3381

  2055

  PDF: 693

  HTML: 26
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  Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

  Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng

  02-10-2023

  https://doi.org/10.4081/ejh.2023.3839

  1410

  PDF: 788

  HTML: 37
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  High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

  Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari

  16-12-2024

  https://doi.org/10.4081/ejh.2024.4145

  1339

  PDF: 389

  HTML: 7
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  Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: a clue to enhance endometrial receptivity in recurrent implantation failure

  Haixia Li, Ning Sun, Yaqiao Zhu, Wei Wang, Meihong Cai, Xiaohuan Luo, Wei Xia, Song Quan

  22-12-2022

  https://doi.org/10.4081/ejh.2023.3580

  1627

  PDF: 961

  HTML: 44
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  miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

  Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li

  22-09-2025

  https://doi.org/10.4081/ejh.2025.4239

  473

  PDF: 324

  Supplementary: 52

  HTML: 18
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  Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

  Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang

  01-08-2023

  https://doi.org/10.4081/ejh.2023.3784

  1915

  PDF: 857

  HTML: 21