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  Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

  Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun

  07-04-2025

  https://doi.org/10.4081/ejh.2025.4182

  914

  PDF: 480

  HTML: 29
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  miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

  Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi

  23-09-2025

  https://doi.org/10.4081/ejh.2025.4238

  261

  PDF: 192

  HTML: 8
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  TRAIL, DR5 and caspase 3-dependent apoptosis in vessels of diseased human temporomandibular joint disc. An immunohistochemical study

  C. Loreto, L. E. Almeida, M.R. Migliore, M. Caltabiano, R. Leonardi

  e40

  13-09-2010

  https://doi.org/10.4081/ejh.2010.e40

  2516

  PDF: 547

  HTML: 1594
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  Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

  Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li

  21-01-2025

  https://doi.org/10.4081/ejh.2025.4158

  1458

  PDF: 462

  Supplementary Figure: 49

  HTML: 36
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  Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

  Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li

  25-10-2022

  https://doi.org/10.4081/ejh.2022.3529

  1475

  PDF: 722

  HTML: 32
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  Protective effect of different antioxidant agents in UVB-irradiated keratinocytes

  Sara Salucci, Sabrina Burattini, Francesca Buontempo, Alberto Maria Martelli, Elisabetta Falcieri, Michela Battistelli

  18-09-2017

  https://doi.org/10.4081/ejh.2017.2784

  2239

  PDF: 947

  HTML: 172
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  Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

  Dajie Wang, Zhaofeng Zhou, Liang Yuan

  20-09-2022

  https://doi.org/10.4081/ejh.2022.3505

  1105

  PDF: 532

  HTML: 34
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  Apoptosis activation in human carious dentin. An immunohistochemical study

  C. Loreto, A. Psaila, G. Musumeci, S. Castorina, R. Leonardi

  09-07-2015

  https://doi.org/10.4081/ejh.2015.2513

  1973

  PDF: 627

  HTML: 943
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  Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

  Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan

  11-11-2022

  https://doi.org/10.4081/ejh.2022.3563

  1344

  PDF: 765

  Supplementary: 87

  HTML: 28
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  Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats

  Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng

  12-01-2022

  https://doi.org/10.4081/ejh.2022.3328

  1958

  PDF: 1093

  HTML: 78
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  Alterations in chromosomal synapses and DNA repair in apoptotic spermatocytes of Mus m. domesticus

  E. Ayarza, M. González, F. López, R. Fernández-Donoso, J. Page, S. Berrios

  14-06-2016

  https://doi.org/10.4081/ejh.2016.2677

  2031

  PDF: 719

  HTML: 381
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  Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

  Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin

  23-10-2024

  https://doi.org/10.4081/ejh.2024.4098

  1786

  PDF: 338

  HTML: 8
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  Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker’s organ in vivo in early stage after birth in rats

  Jun Liu, Linbin Cai, Yuanyuan He, Jun Yang

  07-08-2017

  https://doi.org/10.4081/ejh.2017.2706

  2219

  PDF: 697

  HTML: 210

• The role of miRNA-29b1 on the hypoxia-induced apoptosis in mammalian cardiomyocytes

  Bo Dai, Hailin Liu, Dingmin Juan, Kaize Wu, Ruhao Cao

  27-06-2024

  https://doi.org/10.4081/ejh.2024.4021

  864

  PDF: 392

  HTML: 9
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  Immunohistochemical and ultrastructural visualization of different routes of oocyte elimination in adult rats

  M.L. Escobar Sánchez, O.M. Echeverría Martínez, G.H. Vázquez-Nin

  e17

  16-04-2012

  https://doi.org/10.4081/ejh.2012.17

  1619

  PDF: 697

  HTML: 9362
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  Glyphosate, AMPA and glyphosate-based herbicide exposure leads to GFAP, PCNA and caspase-3 increased immunoreactive area on male offspring rat hypothalamus

  Ewing Duque-Díaz, Hernán Hurtado Giraldo, Linda P. Rocha-Muñoz, Rafael Coveñas

  13-10-2022

  https://doi.org/10.4081/ejh.2022.3428

  1493

  HTML: 63

  PDF: 698
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  Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

  Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang

  01-09-2025

  https://doi.org/10.4081/ejh.2025.4217

  375

  PDF: 117

  HTML: 4
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  Forever particles: histochemistry in the plasticene age

  Beatrice Camia, Andrea Casasco, Manuela Monti

  01-08-2025

  https://doi.org/10.4081/ejh.2025.4226

  590

  PDF: 310

  HTML: 13
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  Immunohistochemical and ultrastructural study of the lamellae of oocytes in atretic follicles in relation to different processes of cell death

  M.L. Escobar, O.M. Echeverría, G. García, R. Ortíz, G.H. Vázquez-Nin

  12-08-2015

  https://doi.org/10.4081/ejh.2015.2535

  1734

  PDF: 626

  HTML: 903
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  Correlation between PARP-1 immunoreactivity and cytomorphological features of parthanatos, a specific cellular death in breast cancer cells

  P. Donizy, A. Halon, P. Surowiak, G. Pietrzyk, C. Kozyra, R. Matkowski

  e35

  20-11-2013

  https://doi.org/10.4081/ejh.2013.e35

  3591

  PDF: 751

  HTML: 329
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  Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse

  A. Vetuschi, A. D'Alfonso, R. Sferra, D. Zanelli, S. Pompili, F. Patacchiola, E. Gaudio, G. Carta

  16-02-2016

  https://doi.org/10.4081/ejh.2016.2604

  1999

  PDF: 853

  HTML: 617
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  Immunological detection of m- and µ-calpains in the skeletal muscle of Marchigiana cattle

  E. Varricchio, M.G. Russolillo, L. Maruccio, S. Velotto, G. Campanile, M. Paolucci, F. Russo

  e2

  14-01-2013

  https://doi.org/10.4081/ejh.2013.e2

  1925

  PDF: 699

  HTML: 524
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  circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

  Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao

  22-08-2025

  https://doi.org/10.4081/ejh.2025.4230

  251

  PDF: 194

  HTML: 2
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  SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

  Yiyu Qin, Jian Li, Hongchao Han, Yongliang Zheng, Haiming Lei, Yang Zhou, Hongyan Wu, Guozhe Zhang, Xiang Chen, Zhengping Chen

  28-12-2023

  https://doi.org/10.4081/ejh.2023.3899

  955

  PDF: 253

  HTML: 4
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  Gemst: a taylor-made combination that reverts neuroanatomical changes in stroke

  Arturo Mangas, Javier Yajeya, Noelia González, Isabel Ruiz, Marianny Pernía, Michel Geffard, Rafael Coveñas

  25-05-2017

  https://doi.org/10.4081/ejh.2017.2790

  1621

  PDF: 636

  HTML: 192
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  Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

  Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

  06-08-2025

  https://doi.org/10.4081/ejh.2025.4228

  643

  PDF: 314

  HTML: 11
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  Effect of alendronate on endochondral ossification in mandibular condyles of growing rats

  V. Bradaschia-Correa, F.A.C. Barrence, L.B. Ferreira, L.F. Massa, V.E. Arana-Chavez

  e24

  25-05-2012

  https://doi.org/10.4081/ejh.2012.24

  1363

  PDF: 662

  HTML: 5699

• P58 | VITAMIN D ATTENUATES LIVER INJURY BY REDUCING APOTOSIS, PYROPTOSIS, FERROPTOSIS AND PROMOTING REGENERATION IN TYPE 2 DIABETES S. Rzeyeva¹, N. Bayromava², T. Ozbilenler¹, A. Akdemir³, M. Anapalı Aykaç⁴, D. Aydemir⁵, F. Kaya Dagistanli¹, T. Ulutin¹, O. Uysal¹, M. Ozturk⁶ | ¹Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul, Türkiye; ²Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul, Türkiye; ³Karabuk University, Faculty of Medicine, Karabük, Türkiye; ⁴Ataturk University, Faculty of Medicine, Erzurum, Türkiye; ⁵Istanbul University, Faculty of Medicine, Istanbul, Türkiye; ⁶Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul Türkiye

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4383

  192
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  Histochemistry as a unique approach for investigating normal and osteoarthritic cartilage

  G. Musumeci, P. Castrogiovanni, V. Mazzone, M.A. Szychlinska, S. Castorina, C. Loreto

  15-04-2014

  https://doi.org/10.4081/ejh.2014.2371

  3404

  PDF: 1074

  HTML: 3147
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  Transfer of Fas (CD95) protein from the cell surface to the surface of polystyrene beads coated with anti-Fas antibody clone CH-11

  H. Sawai, N. Domae

  e8

  04-02-2010

  https://doi.org/10.4081/ejh.2010.e8

  1269

  PDF: 424

  HTML: 1382
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  Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses

  L.O.C. de Moraes, F.R. Lodi, T. S. Gomes, C.T.F. Oshima, S.R. Marques, C.L.P. Lancellotti, J.F. Rodriguez-Vázquez, J.R. Mérida-Velasco, L.G. Alonso

  e24

  21-07-2011

  https://doi.org/10.4081/ejh.2011.e24

  1493

  PDF: 576

  HTML: 1697
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  MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9

  Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen

  12-01-2022

  https://doi.org/10.4081/ejh.2022.3275

  1748

  PDF: 714

  Supplementary: 128

  HTML: 31

• P65 | (YS) INVESTIGATING THE EFFECTS OF THE SECRETOME FROM HUMAN AMNIOTIC MESENCHYMAL STROMAL CELLS ON INFLAMMASOME ACTIVATION M. Rossi¹, M. Magatti², P. Romele², E. Vertua², E. Giuzzi², S. Farigu², L. Marelli², B. Rapuzzi², S. De Munari², A. Silini², O. Parolini³ | ¹Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, and Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; ²Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; ³Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy & Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4390

  178
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  Expression of lumican and fibromodulin following interleukin-1 beta stimulation of disc cells of the human temporomandibular joint

  N. Kiga, I. Tojyo, T. Matsumoto, Y. Hiraishi, Y. Shinohara, S. Makino, S. Fujita

  e11

  01-04-2011

  https://doi.org/10.4081/ejh.2011.e11

  1559

  PDF: 660

  HTML: 1870
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  The possible alleviating effect of garlic supplement on the neural retina in a rat model of hypercholesterolemia: a histological and immunohistochemical study

  Eetmad A. Arafat, Eman M.I. Youssef, Hanaa A. Khalaf

  16-12-2021

  https://doi.org/10.4081/ejh.2021.3322

  1028

  PDF: 465

  HTML: 17

• P83 | INFLAMMATORY PROFILE IN SKIN, LUNG, AND KIDNEY OF A HOCL-INDUCED MURINE MODEL OF SYSTEMIC SCLEROSIS: AN IMMUNOHISTOCHEMICAL STUDY G. Vermiglio¹, J. Freni¹, F. Nicita¹, A. Centofanti¹, D. Labellarte¹, E. Rizzuto¹, A. Favaloro¹, M. Runci Anastasi², G.P. Anastasi¹, G. Cutroneo¹ | ¹Department of Biomedical, Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy; ²Department of Maxillo-Facial Surgery, University of Rome, La Sapienza, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4409

  189
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  An ex vivo study on immunohistochemical localization of MMP-7 and MMP-9 in temporomandibular joint discs with internal derangement

  C. Loreto, R. Leonardi, G. Musumeci, G. Pannone, S. Castorina

  e12

  15-04-2013

  https://doi.org/10.4081/ejh.2013.e12

  2611

  PDF: 775

  HTML: 425
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  Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

  R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone

  26-10-2015

  https://doi.org/10.4081/ejh.2015.2547

  1727

  PDF: 987

  HTML: 347
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  Activation of Hedgehog pathway by circEEF2/miR-625-5p/TRPM2 axis promotes prostate cancer cell proliferation through mitochondrial stress

  ChenHui Zhu, LiJuan Lin, ChangQing Huang, ZhiHui Wu

  11-11-2024

  https://doi.org/10.4081/ejh.2024.4063

  1343

  PDF: 373

  HTML: 5
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  Co-overexpression of bcl-2 and c-myc in uterine cervix carcinomas and premalignant lesions

  Z. Protrka, S. Arsenijevic, A. Dimitrijevic, S. Mitrovic, V. Stankovic, M. Milosavljevic, T. Kastratovic, J. Djuric

  e8

  16-03-2011

  https://doi.org/10.4081/ejh.2011.e8

  989

  PDF: 573

  HTML: 3025
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  Effects of different rearing temperatures on muscle development and stress response in the early larval stages of Acipenser baerii

  Lucia Aidos, Luisa M. Pinheiro Valente, Vera Sousa, Marco Lanfranchi, Cinzia Domeneghini, Alessia Di Giancamillo

  28-11-2017

  https://doi.org/10.4081/ejh.2017.2850

  2022

  PDF: 580

  HTML: 169
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  Chemotherapy-induced nephrotoxicity was improved by crocin in mouse model

  Qichao Yin, Hua Xiong

  03-10-2022

  https://doi.org/10.4081/ejh.2022.3541

  932

  PDF: 567

  HTML: 26
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  Analysis of ERK3 intracellular localization: dynamic distribution during mitosis and apoptosis

  F. Aredia, M. Malatesta, P. Veneroni, M.G. Bottone

  01-12-2015

  https://doi.org/10.4081/ejh.2015.2571

  2243

  PDF: 723

  HTML: 759
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  Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

  C. Pellicciari

  e51

  16-12-2010

  https://doi.org/10.4081/ejh.2010.e51

  1365

  PDF: 663

  HTML: 3862
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  On the future contents of a small journal of histochemistry

  C. Pellicciari

  e51

  10-12-2012

  https://doi.org/10.4081/ejh.2012.e51

  2326

  PDF: 917

  HTML: 932

• IMPAIRMENT OF HERP E3 LIGASE ACTIVITY BY MUTANT POLYGLUTAMINE PROTEINS: A NOVEL MECHANISM IN POLYGLUTAMINE DISEASE NEUROPATHOLOGY T. Peng, B. Zhang, M. Yang, H. Li | Department of Histology and Embryology, School of Basic Medical Sciences, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4316

  186
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  Expression of hyaluronan synthase 3 in deformed human temporomandibular joint discs: in vivo and in vitro studies

  T. Matsumoto, M. Inayama, I. Tojyo, N. Kiga, S. Fujita

  e50

  15-12-2010

  https://doi.org/10.4081/ejh.2010.e50

  1558

  PDF: 619

  HTML: 1259
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  Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

  Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui

  15-02-2022

  https://doi.org/10.4081/ejh.2022.3316

  1692

  PDF: 666

  HTML: 21

• EXPLORING THE CYTOTOXIC AND APOPTOTIC ACTIVITIES OF PRUNUS SPINOSA ECOTYPE EXTRACT TRIGNO ON 3D AND 2D MODELS OF HUMAN CANCER CELLS A. Di Netta¹, A. Di Pauli², R. Vona³, C. Cittadini³, S. Meschini¹, M. Condello¹ | ¹ National Center for Drug Research and Evaluation, National Institute of Health, Rome, Italy; ² Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, «Sapienza» University of Rome, Rome, Italy: ³ National Center for Gender-Specific Medicine, National Institute of Health, Rome, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4319

  182