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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Activation of Hedgehog pathway by circEEF2/miR-625-5p/TRPM2 axis promotes prostate cancer cell proliferation through mitochondrial stress

    ChenHui Zhu, LiJuan Lin, ChangQing Huang, ZhiHui Wu
    11-11-2024
    https://doi.org/10.4081/ejh.2024.4063
    1573
    PDF: 531
    HTML: 15
  • MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9

    Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3275
    1968
    PDF: 801
    Supplementary: 148
    HTML: 34
  • Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

    Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4034
    1151
    PDF: 571
    HTML: 10
  • The role of miR-143-3p/FNDC1 axis on the progression of non-small cell lung cancer

    Zhanshu Ma, Qi Gao, Wenjing Xin, Lei Wang, Yan Chen, Chang Su, Songyan Gao, Ruiling Sun
    03-05-2023
    https://doi.org/10.4081/ejh.2023.3577
    1929
    PDF: 594
    HTML: 33
  • miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

    Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4161
    1434
    PDF: 460
    HTML: 26
  • Sodium hyaluronate promotes proliferation, autophagy, and migration of corneal epithelial cells by downregulating miR-18a in the course of corneal epithelial injury

    Yingzhuo Guo, Hua Wang
    15-06-2023
    https://doi.org/10.4081/ejh.2023.3663
    1335
    PDF: 627
    Supplementary: 120
    HTML: 23
  • The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

    Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3323
    1863
    PDF: 675
    HTML: 31
  • MiR-130a-5p contributed to the progression of endothelial cell injury by regulating FAS

    Wei Wang, Wenbo Tang, Erbo Shan, Lei Zhang, Shiyuan Chen, Chaowen Yu, Yong Gao
    31-05-2022
    https://doi.org/10.4081/ejh.2022.3342
    1131
    PDF: 708
    HTML: 29
  • MiR-122-5p inhibits the epithelial mesenchymal transition of liver cancer cells by inducing hiPSCs to differentiate into hepatocyte-like cells

    Qianzhe Xing, Yanjie Xu, Ying Luo, Chenglong Li, Peng Wang, Bin Kang, Chengjun Lu
    06-05-2025
    https://doi.org/10.4081/ejh.2025.4190
    725
    PDF: 385
    HTML: 31
  • Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

    Dajie Wang, Zhaofeng Zhou, Liang Yuan
    20-09-2022
    https://doi.org/10.4081/ejh.2022.3505
    1290
    PDF: 593
    HTML: 39
  • Long noncoding RNA H19 accelerates tenogenic differentiation by modulating miR-140-5p/VEGFA signaling

    You-Jie Liu, Hua-Jun Wang, Zhao-Wen Xue, Lek-Hang Cheang, Man-Seng Tam, Ri-Wang Li, Jie-Ruo Li, Hui-Ge Hou, Xiao-Fei Zheng
    07-09-2021
    https://doi.org/10.4081/ejh.2021.3297
    1794
    PDF: 946
    Supplementary: 164
    HTML: 25
  • LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway

    Yong Jiang, Chun-hui Xu, Ying Zhao, Yun-han Ji, Xin-tao Wang, Ying Liu
    16-01-2023
    https://doi.org/10.4081/ejh.2023.3526
    1716
    PDF: 798
    HTML: 58
  • Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

    Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li
    17-05-2023
    https://doi.org/10.4081/ejh.2023.3612
    1366
    PDF: 913
    Supplementary: 96
    HTML: 21
  • miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

    Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3237
    1494
    PDF: 569
    HTML: 25
  • MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

    Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3426
    1448
    PDF: 811
    HTML: 25
  • Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

    Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du
    05-05-2025
    https://doi.org/10.4081/ejh.2025.4178
    858
    PDF: 378
    Supplementary: 49
    HTML: 47
  • Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

    Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera
    20-04-2022
    https://doi.org/10.4081/ejh.2022.3409
    1767
    PDF: 910
    HTML: 27
  • miR-19a targeting CLCA4 to regulate the proliferation, migration, and invasion of colorectal cancer cells

    Huiwen Li, Bo Huang
    10-03-2022
    https://doi.org/10.4081/ejh.2022.3381
    2051
    PDF: 690
    HTML: 26
  • Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

    Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3766
    1954
    PDF: 1251
    HTML: 15
  • Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

    Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
    17-04-2025
    https://doi.org/10.4081/ejh.2025.4176
    1340
    PDF: 596
    Supplementary: 109
    HTML: 44
  • Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

    Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui
    15-02-2022
    https://doi.org/10.4081/ejh.2022.3316
    1836
    PDF: 734
    HTML: 25
  • circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

    Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao
    22-08-2025
    https://doi.org/10.4081/ejh.2025.4230
    362
    PDF: 283
    HTML: 5
  • Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

    Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li
    25-10-2022
    https://doi.org/10.4081/ejh.2022.3529
    1700
    PDF: 803
    HTML: 36
  • MiR-550a-3p restores damaged vascular smooth muscle cells by inhibiting thrombomodulin in an in vitro atherosclerosis model

    Shiyuan Chen, Longfei Zhang, Benchi Feng, Wei Wang, Delang Liu, Xinyu Zhao, Chaowen Yu, Xiaogao Wang, Yong Gao
    19-07-2022
    https://doi.org/10.4081/ejh.2022.3429
    1200
    PDF: 646
    Supplementary: 132
    HTML: 35
  • Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

    Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou
    22-06-2022
    https://doi.org/10.4081/ejh.2022.3394
    1937
    PDF: 1265
    HTML: 27
  • Contribution of intestinal smooth muscle to Crohn's disease fibrogenesis

    C. Severi, R. Sferra, A. Scirocco, A. Vetuschi, N. Pallotta, A. Pronio, R. Caronna, G. Di Rocco, E. Gaudio, E. Corazziari, P. Onori
    17-12-2014
    https://doi.org/10.4081/ejh.2014.2457
    2922
    PDF: 1140
    HTML: 435
  • SHORT-TERM EXPOSURE TO PARTICULATE MATTER TRIGGERS SELECTIVE MOLECULAR AND BEHAVIORAL ALTERATIONS IN A MOUSE MODEL OF MULTIPLE SCLEROSIS Bonato M1,2, Montarolo F1,2, Cerrato V1,2, Parolisi R1,2, Abbadessa G3, Caudana M3, Di Cintio N1,2, De Francia S3, Bertolotto A2,4, Buffo A1,2, and Boda E1,2 | 1Dept. of Neuroscience Rita Levi Montalcini, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Orbassano (Turin), Italy; 3Department of Clinical and Biological Sciences, University of Turin, Orbassano (Turin), Italy; 4Koelliker Hospital, Turin, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4482
    264
  • The role of miRNA-29b1 on the hypoxia-induced apoptosis in mammalian cardiomyocytes

    Bo Dai, Hailin Liu, Dingmin Juan, Kaize Wu, Ruhao Cao
    27-06-2024
    https://doi.org/10.4081/ejh.2024.4021
    1017
    PDF: 480
    HTML: 26
  • Stem cell populations in the heart and the role of Isl1 positive cells

    V. Di Felice, G. Zummo
    e14
    09-05-2013
    https://doi.org/10.4081/ejh.2013.e14
    2923
    PDF: 1144
    HTML: 118
  • Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells via regulation of miR-1234/TP53I11 axis

    Jinbi Xie, Yong Ning, Lihang Zhang, Yuan Lin, Runsheng Guo, Shanjuan Wang
    03-10-2022
    https://doi.org/10.4081/ejh.2022.3477
    1978
    PDF: 643
    HTML: 39
  • RNA therapeutics - Function, design and delivery

    Carlo Alberto Redi
    br7
    17-06-2011
    https://doi.org/10.4081/ejh.2011.br7
    921
    PDF: 437
    HTML: 172
  • LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma

    Nuobei Zhang, Hao Shen, Shenan Huang, Fenfen Wang, Huifang Liu, Fen Xie, Lei Jiang, Xin Chen
    16-11-2021
    https://doi.org/10.4081/ejh.2021.3300
    1268
    PDF: 651
    HTML: 49
  • Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

    Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu
    17-11-2025
    https://doi.org/10.4081/ejh.2025.4426
    858
    PDF: 477
    HTML: 16
  • miR-29a-3p enhances the radiosensitivity of oral squamous cell carcinoma cells by inhibiting ADAM12

    Cuihong Jiang, Feng Liu , Shuai Xiao, Lili He, Wenqiong Wu, Qi Zhao
    27-09-2021
    https://doi.org/10.4081/ejh.2021.3295
    1346
    PDF: 900
    HTML: 27
  • Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cells via miR-6739-5p modulation and PI3K/AKT pathway activation: a functional histocytochemical study

    Zefeng Sun, Xinrong Fan, Zhenquan Liu
    02-10-2025
    https://doi.org/10.4081/ejh.2025.4253
    373
    PDF: 327
    HTML: 37
  • Long non-coding RNA WAC antisense RNA 1 mediates hepatitis B virus replication in vitro by reinforcing miR-192-5p/ATG7-induced autophagy

    Minkai Cao, Deping Yuan, Hongxiu Jiang, Guanlun Zhou, Chao Chen, Guorong Han
    02-09-2022
    https://doi.org/10.4081/ejh.2022.3438
    1486
    PDF: 899
    HTML: 44
  • Deletion of osteopontin in non-small cell lung cancer cells affects bone metabolism by regulating miR-34c/Notch1 axis: a clue to bone metastasis

    Jing Guo, Chang-Yong Tong, Jian-Guang Shi, Xin-Jian Li, Xue-Qin Chen
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3631
    1343
    PDF: 743
    HTML: 25
  • Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

    Jun Lin, Liping Jiang, Kun Guo, Ning Feng
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3528
    1979
    PDF: 1202
    Supplementary: 129
    HTML: 37
  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    1134
    PDF: 511
    HTML: 18
  • The hematopoietic stem cells supportive megakaryocytes as shapers of the bone marrow niche

    Francesca Arciprete, Viola Velardi, Paola Verachi, Claudio Carta, Antonio Di Virgilio, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello
    16-12-2025
    https://doi.org/10.4081/ejh.2025.4424
    673
    PDF: 283
    HTML: 13
  • Curculigoside inhibits osteoarthritis via the regulation of NLRP3 pathway

    Xufei Wang, Yinlian Liu, Yongnian Zhou, Yang Zhou, Yueping Li
    13-12-2023
    https://doi.org/10.4081/ejh.2023.3896
    1399
    PDF: 668
    HTML: 23
  • Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

    Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3839
    1403
    PDF: 786
    HTML: 37
  • Apoptosis - Methods and Protocols

    CarloAlberto Redi
    e13
    19-03-2010
    https://doi.org/10.4081/ejh.2010.e13
    1224
    PDF: 469
    HTML: 212
  • Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma

    Zhiyang Wang, Jing Li, Ziwei Liu, Ling Yue
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3622
    1218
    PDF: 743
    HTML: 34
  • miRNA-877-5p inhibits malignant progression of prostate cancer by directly targeting SSFA2

    Wanchun Wang, Jun Yi, Degang Dong, Wenli Mao, Xuanyu Wang, Zhangren Yan
    20-09-2021
    https://doi.org/10.4081/ejh.2021.3243
    1372
    PDF: 660
    HTML: 38
  • The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

    Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang
    01-03-2023
    https://doi.org/10.4081/ejh.2023.3648
    3257
    PDF: 1047
    HTML: 43
  • miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

    Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li
    22-09-2025
    https://doi.org/10.4081/ejh.2025.4239
    459
    PDF: 320
    Supplementary: 52
    HTML: 18
  • LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

    Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu
    31-05-2023
    https://doi.org/10.4081/ejh.2023.3535
    1127
    PDF: 634
    HTML: 33
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European Journal of Histochemistry

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