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P70 | TRICHOSANTHIN TARGETS WNT/NF-KB PATHWAYS TO ATTENUATE PSORIATIC INFLAMMATION AND KERATINOCYTE HYPERPROLIFERATION K. Wang1, W. Li1, Z. Ying1, C. Li2, O. Sha1 | 1Department of Anatomy and Histology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen, China; 2Department of Anatomy, Shantou University Medical College, Shantou, China
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Ferritin expression in the periodontal tissues of primates
1373PDF: 765HTML: 24 -
Interindividual variability in the expression of surfactant protein A and B in the human lung during development
2109PDF: 819Supplementary: 274HTML: 389 -
P38 | THE ROLE OF SPEXIN IN COLORECTAL CANCER J. Kiezun1, J. Godlewski1, M. Kiezun2, M. Gudelska1, K. Kisielewska1, A. E. Kowalczyk1, B. E. Krazinski1 | 1Department of Anatomy and Histology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland; 2Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Poland
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Diagnosis of sudden cardiac death due to early myocardial ischemia: An ultrastructural and immunohistochemical study
2866PDF: 1360Supplementary: 267HTML: 83 -
Lorenzo Gotte (1926-1991): a pioneer of elastin
1491PDF: 707HTML: 210 -
Syndecan expressions in the human amnion and chorionic plate
1939PDF: 692HTML: 796 -
ECRG4 expression in normal rat tissues: expression study and literature review
3122PDF: 1220Supplementary: 415HTML: 1021 -
P15 | PHB/JAK/H3Y41PH AXIS REGULATES MEIOTIC RECOMBINATION IN SPERMATOGENESIS H. Chen1, L. Zhang1, W. Tan-Tai1, M. Liu2, H. Shi3, W. O4, P.A. Martin-DeLeon5 | 1Department of Anatomy, Histology & Embryology, Shanghai Medical College, Fudan University, Shanghai, China; 2State Key Laboratory of Molecular Biology, Chinese Academy of Sciences-University of Chinese Academy of Sciences, Shanghai, China; 3NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China; 4School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China; 5Department of Biological Sciences, University of Delaware, Newark, USA
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Subcutaneous adipose tissue classification
4092PDF: 1425HTML: 2699 -
THE DUAL EFFECT OF CADMIUM IN ASTROCYTE PHYSIOLOGY: FROM ADAPTIVE ACTIVATION TO POTENTIAL NEUROTOXICITY Branca JJV, Guarnieri G, Mencarelli F, Gulisano M, Morelli A and Pacini A | Department of Experimental and Clinical Medicine, Anatomy and Histology Section, University of Firenze, Firenze, Italy
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NANOVESICLES IN THE GUT–BRAIN AXIS: INSIGHTS FROM PROBIOTIC SUPPLEMENTATION IN IRRITABLE BOWEL SYNDROME C. Caruso Bavisotto, F. Cappello | Section of Human Anatomy, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy
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ROLE OF SCHWANN CELLS-CANCER CELLS CROSSTALK IN TUMOUR PROGRESSION C. Giampietri1, E. Pizzichini1, F. Somma1, S. Petrungaro1, A. Facchiano2, A. Filippini1, C. Fabrizi1, E. Gaudio1 | 1Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Rome, Italy; 2Istituto Dermopatico dell’Immacolata, IDI-IRCCS, Rome, Italy
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P36 | BIOLOGICAL ROLE OF DNA G-QUADRUPLEX DURING LIVER REGENERATION AFTER PARTIAL HEPATECTOMY T. Ishizuka, K. M. Aung, T. Kubota, B. Lkham-Erdene, K. Kai, Y. Hishikawa | Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
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Histochemistry for nanomedicine: Novelty in tradition
1213PDF: 531HTML: 23 -
CRAFTING THE MICROVASCULAR CANVAS: BIOENGINEERED MATERIALS OR NATIVE EXTRACELLULAR MATRIX FOR THE CENTRAL NERVOUS SYSTEM De Luca C1, Virtuoso A1, Cirillo G1, De Angelis F1, Guedán A2, Maduna T3, Morin A4, Sepulveda Diaz J4, Vlachos A3,5,6, Panetsos F7, Pérez-Rigueiro J8 and Papa M1,9 | 1Laboratory of Morphology of Neuronal Networks and Systems Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; 2Bioactive Surfaces S.L., Madrid, Spain; 3Department of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany; 4Microfluidics Innovation Center, Paris, France; 5Center for Basics in Neuromodulation (NeuroModulBasics), Faculty of Medicine. University of Freiburg, Freiburg, Germany 6Center BrainLinks-BrainTools, University of Freiburg, Freiburg, Germany; 7Universidad Complutense de Madrid, Madrid, Spain 8Universidad Politécnica de Madrid, Spain; 9SYSBIO Centre of Systems Biology ISBE-IT, Milan, Italy
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EXPLORING THE CYTOTOXIC AND APOPTOTIC ACTIVITIES OF PRUNUS SPINOSA ECOTYPE EXTRACT TRIGNO ON 3D AND 2D MODELS OF HUMAN CANCER CELLS A. Di Netta1, A. Di Pauli2, R. Vona3, C. Cittadini3, S. Meschini1, M. Condello1 | 1 National Center for Drug Research and Evaluation, National Institute of Health, Rome, Italy; 2 Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, «Sapienza» University of Rome, Rome, Italy: 3 National Center for Gender-Specific Medicine, National Institute of Health, Rome, Italy
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DISTRIBUTION, DENSITY, AND PHYLOGENETIC VARIATION OF CORTICAL IMMATURE NEURONS IN MACAQUES (RHESUS MONKEY) Pattaro A1,2, Sherwood CC3 and Bonfanti L1,2 | 1Neuroscience Institute Cavalieri Ottolenghi (NICO), Regione Gonzole 10, Orbassano (TO), Italy; 2Department of Veterinary Sciences, University of Turin, Grugliasco (TO), Italy; 3Department of Anthropology and Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington DC, USA
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P82 | PROINFLAMMATORY BONE MARROW NICHES AND NEUTROPHIL ACTIVATION ARE ASSOCIATED WITH TIGIT EXPRESSION IN MULTIPLE MYELOMA V. Velardi1, F. Arciprete1, V. Tomarchio2, G. Vivacqua1, M.A. Tafuri2, M. Di Cecca2, L. Rigacci2, A. Crescenzi3, R. Rana1, O. Annibali2, M. Zingariello1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Unit of Hematology, Stem Cell Transplantation, University Hospital Campus Bio-Medico Rome, Italy; 3Department of Radiological, Oncological, and Pathological Sciences, Sapienza University of Rome, Rome, Italy
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ALPHA SYNUCLEIN REGULATION IN BRAIN AND BONE MARROW IS RELETED TO THE DIFFERENTIAL EXPRESSION OF GATA1 TRANSCRIPTION FACTOR Velardi V1, Arciprete F1, Caturano C1, Rana RA1, Mancinelli R2, Zingariello M1 and Vivacqua G1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy
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P02 | THE C-C CHEMOKINE-RECEPTOR 2 (CCR2)/CCL2 AXIS PARTICIPATE IN PLATELET FUNCTION IN MYELOFIBROSIS F. Arciprete1, V. Velardi1, G. Pozzi2, C. Carubbi3, S. Cortellazzi3, A.M. Vannucchi4, M. Vitale5, R.A. Rana1, G. Vivacqua1, E. Masselli3, M. Zingariello1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; 3Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; 4Center Research and Innovation of Myeloproliferative Neoplasm, University Hospital Careggi, University of Florence, Florence, Italy; 5San Raffaele University, Milano, Italy
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HOW DO THE CYTOSKELETON AND ITS BINDING PARTNERS CONTRIBUTE TO THE ESTABLISHMENT OF THE BRAIN MORPHOLOGY AND ITS FUNCTION? Sato M1,2,3 | 1Department of Anatomy and Neuroscience, Graduate School of Medicine, The University of Osaka, Japan; 2Molecular Brain Sciences, Department of Child Development, United Graduate School of Child Development-Osaka University, Kanazawa University, Hamamatsu University of Medicine, Chiba University and University of Fukui (UGSCD), The University of Osaka, Japan; 3Department of Neurosciences Rita Levi Montalcini, University of Turin, Italy
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P85 | ALTERATION OF SUBMUCOSAL AND MYENTERIC GANGLIA IN SEVERE GUT DYSMOTILITY: A QUANTITATIVE MORPHOMETRIC ANALYSIS H. Yaghi1, E. Boschetti1, S. Blando1, I. Neri1, C. Malagelada2, R. De Giorgio3, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Bologna, Italy; 2Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; 3Department of Translational Medicine, Università di Ferrara, Ferrara, Italy
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SUMOYLATION AS AN EARLY ADAPTIVE MECHANISM IN THE PROTEOMIC RESPONSE OF HUMAN GERM CELLS TO SIMULATED MICROGRAVITY A. Di Pauli1, G. Ricci2, M. Crescenzi3, M. A. Mariggiò4, C. Morabito4, L. Gesualdi1, M. Berardini1, F. Ferranti5, M. Signore6, A. Catizone1 | 1Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, Section of Histology and Embryology, «Sapienza» University, Rome, Italy; 2Department of Experimental Medicine, University «Luigi Vanvitelli», Naples, Italy; 3Core Facilities, Italian National Institute of Health, Rome, Italy; 4Department of Neuroscience, Imaging and Clinical Sciences CAST, «G. d’Annunzio» University, Chieti, Italy; 5Human Spaceflight and Scientific Research Unit, Italian Space Agency, Rome, Italy; 6RPPA unit, Proteomics, Italian National Institute of Health, Rome, Italy
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Cartilage canals in newborn dogs: histochemical and immunohistochemical findings
1590PDF: 762Supplementary: 325HTML: 218 -
P45 | TARGETING PRELAMIN A PROCESSING TO SENSITIZE GLIOBLASTOMA CELLS TO OXIDATIVE STRESS M.V. Marvi1, C. Evangelisti1, I. Rusciano1, I. Neri1, L.I. Cocco1, L. Manzoli1, C. Capanni2, S. Ratti1 | 1Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum-University of Bologna, Bologna, Italy; 2CNR Institute of Molecular Genetics «Luigi Luca Cavalli-Sforza», Unit of Bologna, Bologna, Italy / IRCCS Rizzoli Orthopedi, Institute, Bologna, Italy
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P06 | MICROGRAVITY-INDUCED CHANGES IN CYTOSKELETON STRUCTURE OF TCAM-2 CELLS M. Berardini1, L. Gesualdi1, A. Di Pauli1, M. Signore2, S. Broccolucci1, F. Ferranti3, M. Bizzarri4, M. Tafani4, G. Ricci5, A. Catizone1 | 1Dept of Anatomy, Histology, Forensic-Medicine and Orthopedics,“Sapienza” University of Rome, Rome, Italy; 2RPPA Unit, Proteomics Area, Core Facilities, Istituto Superiore di Sanità, Rome, Italy; 3Human Spaceflight and Scientific Research Unit, Italian Space Agency, Rome, Italy; 4Dept of Experimental Medicine “Sapienza” University of Rome, Rome, Italy; 5Dept of Experimental Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, Italy
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GLIAL INFLAMMASOME ACTIVATION AND BLOOD-BRAIN BARRIER BREAKDOWN IN AGE-RELATED NEURODEGENERATION Errede M1, Girolamo F1, d’Amati A1,2, de Giorgis M1, Lorusso L1, Pierucci C3, Bernardini N3, Pellegrini C3, Virgintino D1 and Annese T2 | 1University of Bari, Department of Translational Biomedicine and Neuroscience – Human Anatomy and Histology Unit, Bari, Italy; 2Libera Università del Mediterraneo (LUM) Giuseppe Degennaro University, Department of Medicine and Surgery, Bari, Italy; 3University of Pisa, Department of Clinical and Experimental Medicine - Unit of Histology and Medical Embryology, Pisa, Italy
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ASTROCYTE DYSFUNCTION IN AUTOSOMAL DOMINANT LEUKODYSTROPHY (ADLD): INSIGHTS FROM 2D AND 3D IN VITRO SYSTEMS AND EX VIVO CEREBROSPINAL FLUID METABOLOMICS F.D. Koufi1, V. Righi2, A. Mucci3, I. Rusciano1, S. Mongiorgi1, M. Shin4, Y. Kosodo4, I. Cani5, P. Cortelli6, E. Giorgio7, G. Ramazzotti1, L. Manzoli1, S. Ratti1 | 1 Cellular Signaling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Department of Life Quality Studies, University of Bologna, Campus of Rimini, Rimini, Italy; 3Department of Geological and Chemical Sciences, University of Modena and Reggio Emilia, Modena, Italy; 4Korea Brain Research Institute (KBRI), Daegu, Republic of Korea; 5Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 6IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; 7Department of Molecular Medicine, University of Pavia, Pavia, Italy; Medical Genetics Unit, IRCCS Mondino Foundation, Pavia, Italy.
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P46 | ANALYSIS OF AQUAPORIN-2 MUTANT MICE T. Matsuzaki1, H. Yamamoto1, K. Sasaki2, H. Kogo1, A. Iizuka-Kogo1, M. Ikezawa1, Y. Tajika1 | 1Dept. of Anatomy and Cell Biology, Graduate School of Medicine, Gunma University, Maebashi, Japan; 2Bioresource Center, Graduate School of Medicine, Gunma University, Maebashi; Faculty of Bioresources and Environmental Science, Ishikawa Prefectural University, Nonoichi, Japan
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2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy
3192PDF: 1761Video 1: 271Video 2: 318HTML: 31 -
P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY S. Blando1, E. Boschetti1, I. Neri1, L. Caporali2, C. Fiorini2, D. Ormanbekova2, C. Malagelada3, I. Rusciano1, V. Carelli2, R. De Giorgio4, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Italy; 2IRCCS Institute of Neurological Sciences of Bologna, Neurogenetics Program, Bologna, Italy; 3Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; 4Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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WHOLE-BRAIN CATECHOLAMINERGIC CONNECTOMICS IN ALZHEIMER’S DISEASE Bellomi FE1, Loffredo G2, Petrocchi F1, Ullman NS1, Caturano C1, Cauzzi E2, Cognini F3, Mittoni F4, LaBarbera L2, Soda P5, D’Amelio M2 and Vivacqua G1 | 1Microscopic and Ultrastructural Anatomy Laboratory, Campus Bio-medico University of Rome, Rome, Italy; 2Molecular Neuroscience Laboratory, Campus Bio-medico University of Rome, Rome, Italy; 3Carl Zeiss S.p.A., Milan, Italy; 4Interconsulting services, RINA Services S.p.A., Rome, Italy; 5Department of Bio-engineering, Campus Bio-medico University of Rome, Rome, Italy
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HOST/PATHOGEN INTERACTIONS AND THE ROLE OF THE BARRIERS: ON THE EDGE BETWEEN HEALTH AND MULTIFACTORIAL/COMPLEX DISEASES G. Di Sante1, A. M. Stabile1, A. Pistilli1, M. Ruggirello1,2, F. Michetti3,4, F. Ria2, M. Rende1 | 1 Department of Surgery and Medicine, Sect. of Human, Clinical and Forensic Anatomy, University of Perugia, Perugia, Italy; 2Department of Translational Medicine and Surgery, Section of General Pathology, University “Cattolica del Sacro Cuore” of Rome, Roma, Italy; 3Department of Medicine, LUM University, Casamassima, Bari, Italy; 4Italy Genes, Rome, Italy
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P55 | ENDOTHELIAL THYMIDINE PHOSPHORYLASE DEFICIENCY TRIGGERS MORPHO-FUNCTIONAL DEGE-NERATION OF ENTERIC NEURONS AND REDUCES INTESTINAL STEM CELL PROLIFERATION I. Neri1, E. Boschetti1, T. Saha2, S. Rommel2, S. Schulte2, M. Gries2, R. De Giorgio3, L. Manzoli1, S. Ratti1, K. Schäfer2 | 1Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Workgroup Enteric Nervous System (AGENS), Department of Informatics and Microsystems Technology, University of Applied, Sciences Kaiserslautern, Zweibrücken, Germany; 3Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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