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The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis
2046PDF: 1077Supplementary: 254HTML: 60 -
Characterization of the role of RILP in cell migration
2758PDF: 1109Supplementary: 313Movie 1: 433Movie 2: 470HTML: 138 -
UNRAVELING GLIAL REMODELING IN SPACE AND TIME DURING GLIOBLASTOMA EVOLUTION Riccio L1, De Luca C1, Rega C1, Papa M1 and Virtuoso A1 | 1Laboratory of Neuronal Networks Morphology and System Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy
412 -
HOST/PATHOGEN INTERACTIONS AND THE ROLE OF THE BARRIERS: ON THE EDGE BETWEEN HEALTH AND MULTIFACTORIAL/COMPLEX DISEASES G. Di Sante1, A. M. Stabile1, A. Pistilli1, M. Ruggirello1,2, F. Michetti3,4, F. Ria2, M. Rende1 | 1 Department of Surgery and Medicine, Sect. of Human, Clinical and Forensic Anatomy, University of Perugia, Perugia, Italy; 2Department of Translational Medicine and Surgery, Section of General Pathology, University “Cattolica del Sacro Cuore” of Rome, Roma, Italy; 3Department of Medicine, LUM University, Casamassima, Bari, Italy; 4Italy Genes, Rome, Italy
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LncRNA FBXO18-AS promotes gastric cancer progression by TGF-β1/Smad signaling
1459PDF: 863Supplementary: 163HTML: 66 -
75 | Β-SITOSTEROL-D-GLUCOSIDE TRIGGERS INTESTINAL INFLAMMATION IN ZEBRAFISH LARVAE POSSIBLY LEADING TO NEURODEGENERATION THROUGH THE GUT-BRAIN AXIS Francesca Terrin1, Sofia Faggin2|3, Chiara Consorti4, Stefania Marcotti5, Paolo Bonaldo4, Maria Cecilia Giron2, Nicoletta Plotegher1, Luisa Dalla Valle1 | 1Department of Biology, University of Padova, Italy; 2Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Italy; 3Institute of Digestive Health Research (IRSD), Toulouse University, France; 4Department of Molecular Medicine, University of Padova, Italy; 5Randall Centre for Cell and Molecular Biophysics, King's College London, London; UK
176PDF: 92 -
LncRNA RP11-708J19.2 promotes colorectal cancer progression by binding to SIRT7 via regulating H3K18ac
476PDF: 194Supplementary: 133HTML: 44 -
AN INDUCED PLURIPOTENT STEM CELL MODEL OF FLVCR1-RELATED NEUROPATHY UNCOVERS MITOCHONDRIAL AND MEMBRANE DISORGANIZATION IN SENSORY NEURONS Zanin Venturini DI1, Kopecka J2, Zhao B3, Yu TW3, Abalai RE1, Metani L1, Salio C4, Riganti C2, Tolosano E1 and Chiabrando D1 | 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center (MBC) “Guido Tarone”, University of Torino, Turin, Italy; 2Department of Oncology, Molecular Biotechnology Center, University of Turin, Italy; 3Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, Harvard Medical School, USA; 4Department of Veterinary Sciences, University of Torino, Turin, Italy
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20 | REPRODUCTIVE DYNAMICS AND PHYSIOLOGICAL CONDITION IN DIFFERENT SIZE CLASSES OF COMMON SOLE (SOLEA SOLEA) FROM THE NORTH-CENTRAL ADRIATIC SEA G. Chemello1, L. Tortora1, C. Santoni1, E. Giorgini1, S. Colella2, G. Gioacchini1 | 1Dept. of Life and Environmental Science, Polytechnic University of Marche, Italy; 2National Research Council (CNR), Institute for Marine Biological Resources and Biotechnology (IRBIM), Italy
135PDF: 95 -
P79 | AN INNOVATIVE FUNCTIONAL COOKIE MODULATES THE MUCOSA AND MYENTERIC PLEXUS IN THE GUT OF 3xTg-AD MOUSE MODEL OF ALZHEIMER’S DISEASE V. Bellitto1, F. Grasselli1, L. Lucernoni1, I. Martinelli2, E. Vittadini1, A.M. Eleuteri1, L. Bonfili1, S.K. Tayebati2, D. Tomassoni1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal Sciences and Health Products, University of Camerino, Camerino, Italy
394 -
5XFAD MOUSE MODEL: INVESTIGATING BRAIN IRON IMBALANCE AND MITOCHONDRIAL FEATURES’ ALTERATION Mezzanotte M1, Chicote J1, Scimia N1, Riganti C2, Porporato PE3 and Stanga S1 | 1Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; 2Department of Oncology, Oncological Pharmacology Lab, University of Turin, Italy; 3Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Italy
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P05 | ENTERIC NERVOUS SYSTEM NEUROPLASTICITY IN COLON OF ANIMAL MODELS OF OBESITY V. Bellitto1, I. Martinelli2, G. Nittari2, S.K. Tayebati2, D. Tomassoni1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal and Health Products Sciences, University of Camerino, Camerino, Italy
255 -
MicroRNA-29b-3p promotes 5-fluorouracil resistance via suppressing TRAF5-mediated necroptosis in human colorectal cancer
2329PDF: 1150Supplementary: 250HTML: 48 -
P09 | THERAPEUTIC POTENTIAL OF NEUROTROPHINS IN AUTISM SPECTRUM DISORDER F. D’Egidio1, M.S. Scenna1, M. d’Angelo1|2, V. Castelli1, A. Cimini1|2 | 1University of L’Aquila, Dpt. of Life, Health and Environmental Sciences, L’Aquila, Italy; 2Sbarro Institute for Cancer Research and Molecular Medicine and Center for Biotechnology, Temple University, Philadelphia, PA, USA
154PDF: 110 -
P51 | DECELLULARIZATION OF HUMAN LUNG SCAFFOLD FOR TUMOR MICROENVIRONMENT MODELLING STUDY A. Mileo1, S. Boccia2, E. Del Genio1, R. Pastore1, M. De Falco3, I. Belviso4 | 1Dept. of Medicine and Health Sciences, University of Molise, Campobasso, Italy; 2Dept. of Biology, University of Naples Federico II, Naples, Italy; 3Dept. of Biology, University of Naples Federico II, Naples, Italy; National Institute of Biostructures and Biosystems (INBB), Rome, Italy; 4Dept. of Wellness, Nutrition and Sport, Telematic University Pegaso, Naples, Italy
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Essential Current Concepts in Stem Cell Biology
3026PDF: 585HTML: 48 -
28 | 3D MORPHO-FUNCTIONAL RECONSTRUCTION OF THE PREPUBERTAL MOUSE OVARY COMBINING NANO-COMPUTED TOMOGRAPHY AND CONFOCAL IMAGING A. Fantinato1|4, G. Fiorentino1|4, A. Parrilli2, G. Brazzale1, V. Merico1, P. Rebuzzini1, D. Cimadomo1|3, S. Garagna1, M. Zuccotti1 | 1Dept. of Biology and Biotechnology, University of Pavia, Italy; 2Empa-Swiss Federal Laboratories for Materials Science and Technology, Switzerland; 3IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Italy; 4Equal contribution
159PDF: 99 -
GENERATION AND CHARACTERIZATION OF A KNOCK-IN MOUSE MODEL FOR FLVCR1-RELATED SENSORY NEUROPATHY Abalai RE1, Marvaldi L2, Ferrini F3, Riganti C1, Zanin Venturini DI1, Metani L1, Tolosano E1 and Chiabrando D1 | 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center “Guido Tarone”, University of Torino, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Italy; 3Dipartimento di Morfofisiologia Veterinaria and Rita Levi Montalcini Center for Brain Repair, Grugliasco (TO), Italy
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Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma
2337PDF: 996Supplementary: 244HTML: 55 -
Morphological and ultrastructural analysis of normal, injured and osteoarthritic human knee menisci
2994PDF: 1477Supplementary: 307HTML: 99 -
Lipofuscin, lipofuscin-like pigments and autofluorescence
4521PDF: 1977HTML: 558 -
76 | DECODING THES PATHOGENESIS: HOW TTC37 SHAPES GUT HOMEOSTASIS AND PERISTALSIS A. Tesoriere1, F. Sernesi1, A. Piersanti1, M. Gasparotto3, L. Dalla Valle1, M. Cananzi2, F. Argenton1 | 1University of Padova, Italy;2University Hospital of Padova, Italy; 3Central Institute of Mental Health, Mannheim, Germany
162PDF: 102 -
P37 | THE ROLE OF ACTIN-BINDING PROTEINS IN ENDOMETRIOSIS W. Arendt1, M. Hałas-Wiśniewska1, M. Gagat2, M. Izdebska1 | 1Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; 2Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland
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GPX4 and GPX7 over-expression in human hepatocellular carcinoma tissues
4209PDF: 1328Supplementary: 533HTML: 682 -
Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle
1782PDF: 862Figures 1 and 2: 145Figures 3 and 4: 132Figure 5: 120 -
22 | TRANSCRIPTIONAL AND POST-TRANSLATIONAL NETWORKS COORDINATE SELECTIVE AUTOPHAGY TO MAINTAIN ORGANELLE HOMEOSTASIS K. Hartfelt1, M. Petraroia2, T. Persichini2, M. Colasanti2, C. Di Malta3, F. Cecconi4, V. Cianfanelli2 | 1Unit of Cell Stress and Survival, Danish Cancer Institute, Copenhagen, Denmark; 2Dept. of Science, University Roma TRE, Rome, Italy; 3Telethon Institute of Genetics and Medicine, Naples, Italy; 4Dept. of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics Research, Catholic University of the Sacred Heart, Rome, Italy
218PDF: 140 -
39 | ENVIRONMENTAL FACTORS INFLUENCE THE PROTECTIVE EFFICACY OF BRASSICA OLERACEA EXTRACTS ON INTESTINAL AND HEPATIC HOMEOSTASIS IN ZEBRAFISH R. Imperatore1, I. Šola2, E. Coccia1, R. Sciarrillo1, M. Paolucci1 | 1Dept. of Sciences and Technologies, University of Sannio, Benevento, Italy; 2Department of Biology, Faculty of Science, University of Zagreb, Croatia
182PDF: 116 -
P08 | COMBINED EFFECTS OF NONYLPHENOL AND STEROID HORMONES ON HUMAN PROSTATE CELL LINE S. Boccia1, A. Mileo2, F. Carrella3, R. Sciarrillo4, A. Capaldo1, M. De Falco5 | 1Dept. of Biology, University Federico II of Naples, Naples, Italy; 2Dept. of Medicine and Health Sciences, University of Molise, Campobasso, Italy; 3Dept. of Science and Technologies, University of Sannio, Benevento, Italy; 4Dept. of Science and Technologies, University of Sannio, Benevento, Italy; 5Dept. of Biology, University Federico II of Naples,; National Institute of Biostructures and Biosystems (INBB), Rome, Italy
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P12 | NEUROBIOLOGICAL IMPACT OF CITRUS BERGAMIA IN THE IDIOPHATIC AUTISM MODEL BTBR D. Minervini1, I. Olivito1, A. Vivacqua2|3, L. Bartella4|5, L. Di Donna4|5, R. Alò1, R.M. Facciolo1 | 1Comparative Neuroanatomy Lab; Biology, Ecology and Earth Sciences Dept., University of Calabria, Rende (CS), Italy; 2Dept. of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Italy; 3Centro Sanitario, University of Calabria, Rende (CS), Italy; 4QUASIORA Lab., AGRINFRA Research Net, University of Calabria, Rende (CS), Italy; 5Chimica and Tecnologie Chimiche Dept., University of Calabria, Rende (CS), Italy
153PDF: 102 -
P62 | FFAR4/GPR120 ACTIVATION COUNTERACTS FIBROGENIC PATHWAYS IN A CHOLESTATIC LIVER INJURY MODEL S. Pompili1, R. Sferra1, F. Ronca1, A. Cappariello2, A. Vetuschi1 | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy; 2Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy
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30 | NANO-COMPUTED TOMOGRAPHY 3D MAPPING OF PRIMARY-TO-PREOVULATORY FOLLICLES IN THE MOUSE OVARY ACROSS LIFESPAN G. Fiorentino1|9, A. Fantinato1|9, A. Parrilli2, T. Marzi3, C. Alippi3|4, R. Bellazzi5, L. Rienzi6|7, F.M. Ubaldi8, A. Vaiarelli8, G. Brazzale1, V. Merico1, P. Rebuzzini1, D. Cimadomo1|7, S. Garagna1, M. Zuccotti1 | 1Dept. of Biology and Biotechnology, University of Pavia, Italy; 2Empa-Swiss Federal Laboratories for Materials Science and Technology, Switzerland; 3Faculty of Informatics, Università della Svizzera italiana, Switzerland; 4Dept. of Electronics, Information, and Bioengineering, Politecnico di Milano, Italy; 5Dept. of Computer, Electrical and Biomedical Engineering, University of Pavia, Italy; 6Dept. of Biomolecular Sciences, University of Urbino, Italy; 7IVIRMA Global Research Alliance, IVIRMA Italia, Italy; 8IVIRMA Global Research Alliance, Clinica Valle Giulia, Italy; 9Equal contribution
177PDF: 105 -
NANOVESICLES IN THE GUT–BRAIN AXIS: INSIGHTS FROM PROBIOTIC SUPPLEMENTATION IN IRRITABLE BOWEL SYNDROME C. Caruso Bavisotto, F. Cappello | Section of Human Anatomy, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy
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Transgenesis techniques - Principles and protocols
1168PDF: 599HTML: 220 -
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells
695PDF: 636Supplementary: 108HTML: 53 -
P39 | NEW PERSPECTIVES FOR THE EXPLOITATION OF FEMALE REPRODUCTIVE POTENTIAL IN MAMMALS: GENERATION OF GRANULOSA-LIKE CELLS FROM HUMAN ADIPOSE MESENCHYMAL STEM CELLS Y. Lacapra1, D. Farini1, G. Salvatore1, M.A. Ucci1, F.G. Klinger2, M. De Felici1, A. Camaio1 | 1Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy: 2Saint Camillus International University of Health Sciences, Rome, Italy
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Expression of the HPV18/E6 oncoprotein induces DNA damage
2232PDF: 926HTML: 246 -
CONTRIBUTION OF MAGNETIC RESONANCE IMAGING ASSOCIATED WITH MACHINE LEARNING TO AN EARLY ASSESSMENT OF THE CONVERSION OF MILD COGNITIVE IMPAIRMENT IN OVERT DEMENTIA Amenta F, Battineni G, Chintalapudi N and Traini E | Clinical Research Centre, School of Medicinal and Health Products Sciences, University of Camerino, Camerino, Italy
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THE ESTABLISHMENT OF A HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED IN VITRO MODEL TO STUDY DIABETIC PERIPHERAL NEUROPATHY Rando S1,2, Muratori L1,2, Contato A2,3, Lorenzati M2,3, Dotta S2,3, Marvaldi L2,3, Buffo A2,3 and Raimondo S1,2 | 1Department of Clinical and Biological Sciences, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi (NICO), Turin, Italy; 3Department of Neuroscience “Rita Levi Montalcini” University of Turin, Turin, Italy
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