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BIOLOGICAL RESPONSE OF TREATMENT WITH SAFFRON PETAL EXTRACT ON CYTOKYNE-INDUCED OXIDATIVE STRESS AND INFLAMMATION IN THE CACO-2/THP1 COCOLTURE MODEL V. Panella1, F. De Cecco2, S. Franceschelli1, M. A. Maggi3, S. Bisti4, A. Bravo Nuevo5, D. D’Ardes1, F. Cipollone1, L. Speranza1 | 1Department of Medicine and Aging Sciences, University «G. D’Annunzio», Chieti; 2Italian Institute of Technology, Genoa, Italy; 3Hortus Novus, L’Aquila, Italy; 4National Institute of Biostructure and Biosystem, Rome, Italy; 5Department of Biomedical Sciences, Philadelphia College of Osteopathic Medicine (PCOM), Philadelphia, USA
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P74 | EXPRESSION OF PISCIDIN, TLR-4, ERK2 AND P-P38 MAPK IN THE ZEBRAFISH GUT EXPOSED TO PCB-126 AND POSSIBLE PROTECTIVE EFFECTS OF GINESTEIN L. Spiccia1, A. Miller2, G.P. Lombardo1, V. Natale1, F. Pellicanò1, S. Marino1, A. Nunnari1, A. Migliorato3, E.R. Laurian1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; 2Department of Veterinary Sciences, University of Messina, Messina, Italy; 3Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, Messina, Italy
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03 | DISTINCTIVE HOMEOSTATIC BALANCE IN CHILDHOOD OBESITY AND ITS RELATIONSHIP WITH BONE HEALTH Maria Felicia Faienza | Pediatric Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Italy
254PDF: 59 -
P58 | VITAMIN D ATTENUATES LIVER INJURY BY REDUCING APOTOSIS, PYROPTOSIS, FERROPTOSIS AND PROMOTING REGENERATION IN TYPE 2 DIABETES S. Rzeyeva1, N. Bayromava2, T. Ozbilenler1, A. Akdemir3, M. Anapalı Aykaç4, D. Aydemir5, F. Kaya Dagistanli1, T. Ulutin1, O. Uysal1, M. Ozturk6 | 1Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul, Türkiye; 2Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul, Türkiye; 3Karabuk University, Faculty of Medicine, Karabük, Türkiye; 4Ataturk University, Faculty of Medicine, Erzurum, Türkiye; 5Istanbul University, Faculty of Medicine, Istanbul, Türkiye; 6Istanbul University-Cerrahpasa, Faculty of Medicine, Istanbul Türkiye
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P83 | INFLAMMATORY PROFILE IN SKIN, LUNG, AND KIDNEY OF A HOCL-INDUCED MURINE MODEL OF SYSTEMIC SCLEROSIS: AN IMMUNOHISTOCHEMICAL STUDY G. Vermiglio1, J. Freni1, F. Nicita1, A. Centofanti1, D. Labellarte1, E. Rizzuto1, A. Favaloro1, M. Runci Anastasi2, G.P. Anastasi1, G. Cutroneo1 | 1Department of Biomedical, Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy; 2Department of Maxillo-Facial Surgery, University of Rome, La Sapienza, Italy
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P10 | BIOLOGICAL ACTIVITIES OF CITRUS LIMON-, VITIS VINIFERA- AND ACTINIDIA DELICIOSA-DERIVED EXTRACELLULAR VESICLES ON HUMAN CACO-2 CELLS M. Destino, E. Carata, B.A. Tenuzzo, E. Panzarini | Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy
104PDF: 38 -
Elastofibroma dorsi: a histochemical and immunohistochemical study
2824PDF: 964HTML: 1104 -
Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species
2340PDF: 1286Supplementary: 123HTML: 225 -
57 | PUNICA GRANATUM-DERIVED EXTRACELLULAR VESICLES EFFECTS ON AN IN VITRO GASTROINTESTINAL BARRIER MODEL OF INTESTINAL INFLAMMATION Mariano Stefania1, Carata Elisabetta2, Moris Destino2, Bernardetta Anna Tenuzzo2, Panzarini Elisa2 | 1Department of Mathematics and Physics “E. De Giorgi”, University of Salento, Lecce, Italy; 2Department of Biological Sciences and Technologies, University of Salento, Lecce, Italy
80PDF: 87 -
THE CHEMISTRY OF NUTRACEUTICALS: DRIVING HEALTH INNOVATIONS AND SHAPING NEW PARADIGMS M. Micucci | Department of Biomolecular Sciences, Urbino University “Carlo Bo”, Urbino, Italy
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GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location
3592PDF: 631Supplementary: 245HTML: 34 -
P24 | NUTRACEUTICAL-MEDIATED EFFECTS IN THE MODULATION OF INFLAMMATORY PROCESSES IN AN IN VITRO MODEL OF HUMAN ENDOMETRIAL STROMAL CELLS L. Pietrobelli1, V.C. Divincenzo1, L. Sileo1, G. Scanavino1, E. Vicini2, L. Campagnolo3, V. Corsetti4, A.M. Tata1 | 1Dept. of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome, Italy; 2Dept. of SAIMAL, Section of Histology, Sapienza University of Rome, Italy; 3Dept. of Biomedicine and Prevention, University of Rome Tor Vergata, Italy; 4Institute of Translational Pharmacology (IFT)-CNR, Rome, Italy
76PDF: 45 -
09 | MODULATION OF ETOSIS BY BIOACTIVE EXTRACTS DERIVED FROM MARINE RESOURCES AND AGRI-FOOD BY-PRODUCTS F. Bellistrì1, G. Abruscato1, M. Perlotti1, A. Lo Muzzo1, C. Gargano1, F. Longo1, M. Mauro1, R. Chiarelli1, V. Arizza1|3, C. Luparello1|3, G. Sarà2|3, M. Vazzana1|3 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Earth and Marine Sciences, Palermo, Italy; 3National Biodiversity Future Center, Palermo, Italy
198PDF: 53 -
76 | DECODING THES PATHOGENESIS: HOW TTC37 SHAPES GUT HOMEOSTASIS AND PERISTALSIS A. Tesoriere1, F. Sernesi1, A. Piersanti1, M. Gasparotto3, L. Dalla Valle1, M. Cananzi2, F. Argenton1 | 1University of Padova, Italy;2University Hospital of Padova, Italy; 3Central Institute of Mental Health, Mannheim, Germany
103PDF: 50 -
Epithelial expression of the hormone leptin by bovine skin
2115PDF: 1459HTML: 33 -
P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini1, S. Leone1, R. Mancinelli1, R. Vaccaro1, M. Catalano2, G. D’Alessandro2, A. Rinaldi2, A. Reccagni2, G. Vivacqua3, A. Franchitto4, P. Onori1, C. Limatola2, E. Gaudio1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; 2Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; 3Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; 4Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy
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04 | MODULATION OF NEUROINFLAMMATION IN IL-1BETA-INDUCED HUMAN ASTROCYTES: EFFECTS OF GREEN LEAVES AND RHIZOMES EXTRACT FROM POSIDONIA OCEANICA (L.) DELILE G. Abruscato1, L. Sileo2, G. Scanavino2, C. Guerriero2, M. Mauro1, M. Vazzana1|3, V. Arizza1|3, C. Luparello1|3, A.M.Tata2 | 1Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Dept. of Biology and Biotechnologies Charles Darwin, Sapienza- University of Rome, Italy; 3National Biodiversity Future Center (NBFC), Italy
302PDF: 64 -
44 | CHARACTERIZATION OF IMMUNE CELLS IN THE ADIPOSE TISSUE OF OBESE MICE TREATED WITH ANTI-OBESITY THERAPIES G.P. Lombardo1, A. Nunnari1, A. Miller2, M. Kotańska3, S. Fiorentino1, E.R. Lauriano1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; 2Department for the Promotion of Human Sciences and Quality of Life, San Raffaele University, Rome, Italy; 3Department of Pharmacodynamics, Jagiellonian University, Medical College, Medyczna 9, Krakow, Poland
116PDF: 50 -
P70 | TRICHOSANTHIN TARGETS WNT/NF-KB PATHWAYS TO ATTENUATE PSORIATIC INFLAMMATION AND KERATINOCYTE HYPERPROLIFERATION K. Wang1, W. Li1, Z. Ying1, C. Li2, O. Sha1 | 1Department of Anatomy and Histology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen, China; 2Department of Anatomy, Shantou University Medical College, Shantou, China
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