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P21 | INVOLVEMENT OF TELOCYTES IN CARDIAC INFLAMMATION CAUSED BY LPS IN MICE AND THE POTENTIAL ANTI-INFLAMMATORY ROLE OF CANNABIS SATIVA L. A. Miller1, G.P. Lombardo2, A. Nunnari2, G. Pirracchio2, M. Kotańska3, C. Condurso4, E.R. Lauriano2, S. Pergolizzi2 | 1Dept. for the Promotion of Human Sciences and Quality of life, San Raffaele University, Rome, Italy; 2Dept. of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; 3Dept. of Pharmacological Screening, Jagiellonian University Medical; College, Kraków, Poland; 4Dept of Veterinary Sciences, University of Messina, Italy
3PDF: 0 -
KAEMPFEROL TARGETS LIPID BALANCE, ENDOCANNABINOID PATHWAYS, AND PPAR-α IN THE RAT CEREBRAL CORTEX AFTER TRANSIENT BILATERAL COMMON CAROTID ARTERY OCCLUSION AND REPERFUSION Serra MP#, Carta G#, Murru E, Boi M, Manca C, Lai Y, Cabboi M, Carta A, Banni S* and Quartu M* | Department of Biomedical Sciences, University of Cagliari, Italy #equal contribution; *co-seniorship
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P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini1, S. Leone1, R. Mancinelli1, R. Vaccaro1, M. Catalano2, G. D’Alessandro2, A. Rinaldi2, A. Reccagni2, G. Vivacqua3, A. Franchitto4, P. Onori1, C. Limatola2, E. Gaudio1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; 2Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; 3Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; 4Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy
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P10 | BIOLOGICAL ACTIVITIES OF CITRUS LIMON-, VITIS VINIFERA- AND ACTINIDIA DELICIOSA-DERIVED EXTRACELLULAR VESICLES ON HUMAN CACO-2 CELLS M. Destino, E. Carata, B.A. Tenuzzo, E. Panzarini | Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy
4PDF: 1 -
04 | MODULATION OF NEUROINFLAMMATION IN IL-1BETA-INDUCED HUMAN ASTROCYTES: EFFECTS OF GREEN LEAVES AND RHIZOMES EXTRACT FROM POSIDONIA OCEANICA (L.) DELILE G. Abruscato1, L. Sileo2, G. Scanavino2, C. Guerriero2, M. Mauro1, M. Vazzana1|3, V. Arizza1|3, C. Luparello1|3, A.M.Tata2 | 1Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Dept. of Biology and Biotechnologies Charles Darwin, Sapienza- University of Rome, Italy; 3National Biodiversity Future Center (NBFC), Italy
51PDF: 19 -
Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway
1840PDF: 589Supplementary Figure: 89HTML: 60 -
MiR-550a-3p restores damaged vascular smooth muscle cells by inhibiting thrombomodulin in an in vitro atherosclerosis model
1223PDF: 661Supplementary: 141HTML: 39 -
73 | PROTECTIVE ROLE FOR OLEOYLETHANOLAMIDE IN THE HUMAN BRAIN: EFFECTS ON THE MODULATION OF NEUROINFLAMMATION AND INSULIN RESISTANCE IN HUMAN ASTROCYTES Lucia Sileo1, Giulia Scanavino1, Silvana Gaetani2, Ada MariaTata1 | 1Dept. of Biology and Biotechnologies "Charles Darwin", University of Rome "Sapienza", Rome, Italy; 2Dept. of Physiology and Pharmacology “Vittorio Erspamer”, University of Rome "Sapienza", Rome, Italy
13PDF: 9 -
P52 | MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL EVALUATION OF THE ANTI-INFLAMMATORY AND ANTIOXIDANT PROPERTIES OF HEMP EXTRACTS ON THE LIVER OF RATS INVOLVED IN INFLAMMATION CAUSED BY LPS A. Miller1, M. Kotanska2, M. Bednarski2, G.P. Lombardo3, V. Natale3, G. Pirracchio3, L. Spiccia3, S. Pergolizzi3, G. Rizzo4, E.R. Lauriano3 | 1Department of Veterinary Sciences, University of Messina, Messina, Italy; 2Department of Pharmacological Screening, Jagiellonian University Medical College, Kraków, Poland: 3Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; 4Department of Clinical and Experimental Medicine, University of Messina, Italy
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P65 | (YS) INVESTIGATING THE EFFECTS OF THE SECRETOME FROM HUMAN AMNIOTIC MESENCHYMAL STROMAL CELLS ON INFLAMMASOME ACTIVATION M. Rossi1, M. Magatti2, P. Romele2, E. Vertua2, E. Giuzzi2, S. Farigu2, L. Marelli2, B. Rapuzzi2, S. De Munari2, A. Silini2, O. Parolini3 | 1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, and Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 2Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 3Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy & Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy
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23 | BIOFUNCTIONALIZED ELECTROSPUN FIBERS FOR SKIN REGENERATION E. Coccia1, R. Imperatore1, E. Mula1|2, M. Paolucci1 | 1Dept. of Sciences and Technologies, University of Sannio, Benevento, Italy; 2Dept. of Organic and Inorganic Chemistry, University of Alcalà, Alcalà de Henares, Spain
13PDF: 8 -
The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis
1912PDF: 972Supplementary: 195HTML: 31 -
Expression of the endocannabinoid receptors in human fascial tissue
3484PDF: 1802HTML: 2364 -
P71 | THE EXTRACELLULAR VESICLE POPULATIONS UNDERWENT ALTERATIONS SUBSEQUENT TO THE PRETREATMENT OF ADIPOSE-DERIVED STEM CELLS WITH MELATONIN RECEPTOR AGONIST B. Sikora, K. Pogoda-Mieszczak, E. Bogunia, A. Skubis-Sikora, P. Czekaj | Department of Cytophysiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Poland
290 -
44 | CHARACTERIZATION OF IMMUNE CELLS IN THE ADIPOSE TISSUE OF OBESE MICE TREATED WITH ANTI-OBESITY THERAPIES G.P. Lombardo1, A. Nunnari1, A. Miller2, M. Kotańska3, S. Fiorentino1, E.R. Lauriano1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; 2Department for the Promotion of Human Sciences and Quality of Life, San Raffaele University, Rome, Italy; 3Department of Pharmacodynamics, Jagiellonian University, Medical College, Medyczna 9, Krakow, Poland
15PDF: 7 -
HUMAN AMNIOTIC MEMBRANE POTENTIAL FOR BONE REPAIR: FROM THE LAB TO THE CLINIC - ROLE OF ITS IMMUNOGENICITY F. Gindraux1,2 | 1CHU Besançon, Service de Chirurgie Maxillo-Faciale et Stomatologie, Besançon, France; 2Université Marie et Louis Pasteur, SINERGIES UR 4662, Besançon, France
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38 | NATURAL ANTIOXIDANTS IN THE FIGHT AGAINST OVARIAN CANCER: IN VITRO EFFECTS OF POLYPHENOLS Lorenzo Ibello, Filomena Mottola, Maria Teresa Gentile, Ilaria Palmieri, Lucia Rocco | Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Università degli Studi della Campania “Luigi Vanvitelli”, Caserta, Italy
21PDF: 8 -
BIOLOGICAL RESPONSE OF TREATMENT WITH SAFFRON PETAL EXTRACT ON CYTOKYNE-INDUCED OXIDATIVE STRESS AND INFLAMMATION IN THE CACO-2/THP1 COCOLTURE MODEL V. Panella1, F. De Cecco2, S. Franceschelli1, M. A. Maggi3, S. Bisti4, A. Bravo Nuevo5, D. D’Ardes1, F. Cipollone1, L. Speranza1 | 1Department of Medicine and Aging Sciences, University «G. D’Annunzio», Chieti; 2Italian Institute of Technology, Genoa, Italy; 3Hortus Novus, L’Aquila, Italy; 4National Institute of Biostructure and Biosystem, Rome, Italy; 5Department of Biomedical Sciences, Philadelphia College of Osteopathic Medicine (PCOM), Philadelphia, USA
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P24 | NUTRACEUTICAL-MEDIATED EFFECTS IN THE MODULATION OF INFLAMMATORY PROCESSES IN AN IN VITRO MODEL OF HUMAN ENDOMETRIAL STROMAL CELLS L. Pietrobelli1, V.C. Divincenzo1, L. Sileo1, G. Scanavino1, E. Vicini2, L. Campagnolo3, V. Corsetti4, A.M. Tata1 | 1Dept. of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome, Italy; 2Dept. of SAIMAL, Section of Histology, Sapienza University of Rome, Italy; 3Dept. of Biomedicine and Prevention, University of Rome Tor Vergata, Italy; 4Institute of Translational Pharmacology (IFT)-CNR, Rome, Italy
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P07 | ULVANS AS AN ECO-FRIENDLY TOOL TO MITIGATE CELLULAR IMPAIRMENT INDUCED BY DEXAMETHASONE IN MYTILUS GALLOPROVINCIALIS N. Caruso1|2, G. De Marco2, M. Galati2, La Pusata2, M. Terranova1|2, V. Parrino2, G. Genovese2, T. Cappello2, M. Maisano2 | 1Dept. of Earth and Marine Sciences, University of Palermo, Palermo, Italy; 2Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy
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miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells
495PDF: 341Supplementary: 57HTML: 20 -
Immuno- and glyco-histochemistry as a tool to evaluate the oregano supplemented feed effects in pig gut
1791PDF: 837Supplementary: 202HTML: 16 -
P47 | ASSESSMENT OF THE ANTI-INFLAMMATORY AND ANTIFIBROTIC EFFECTS OF HUMAN AMNIOTIC EPITHELIAL CELLS AFTER THEIR INTRATRACHEAL ADMINISTRATION IN A MOUSE MODEL OF BLEOMYCIN-INDUCED PULMONARY FIBROSIS E. Kolanko, A. Mazurski, A. Prusek, E. Bogunia, M. Hermyt, P. Czekaj | Department of Cytophysiology, Medical University of Silesia, Katowice, Poland
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