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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • HUMAN AMNIOTIC EPITHELIAL CELLS FOR RETINAL REGENERATION: INVESTIGATING THEIR DIFFERENTIATIVE POTENTIAL IN VITRO R. Pisu1, S. Saponara2, S. Angioni2, E. Peiretti2, S.G. Vitale2, F. Marongiu1 | 1Department of Biomedical Sciences, University of Cagliari, Cagliari; 2Department of Surgical Sciences, University of Cagliari, Cagliari, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4272
    163
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2640
    PDF: 813
    HTML: 343
  • Thymosin beta 4 and thymosin beta 10 expression in hepatocellular carcinoma

    W. Theunissen, D. Fanni, S. Nemolato, E. Di Felice, T. Cabras, C. Gerosa, P. Van Eyken, I. Messana, M. Castagnola, G. Faa
    11-03-2014
    https://doi.org/10.4081/ejh.2014.2242
    3145
    PDF: 999
    HTML: 486
  • Lubricin is expressed in chondrocytes derived from osteoarthritic cartilage encapsulated in poly(ethylene glycol) diacrylate scaffold

    G. Musumeci, C. Loreto, M.L. Carnazza, F. Coppolino, V. Cardile, R. Leonardi
    e31
    15-09-2011
    https://doi.org/10.4081/ejh.2011.e31
    1642
    PDF: 794
    HTML: 3918
  • The Bromodomain testis-specific gene (Brdt) characterization and expression in gilthead seabream, Sparus aurata, and European seabass, Dicentrarchus labrax

    M. Úbeda-Manzanaro, J.B. Ortiz-Delgado, C. Sarasquete
    02-05-2016
    https://doi.org/10.4081/ejh.2016.2638
    1648
    PDF: 796
    HTML: 333
  • Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: a clue to enhance endometrial receptivity in recurrent implantation failure

    Haixia Li, Ning Sun, Yaqiao Zhu, Wei Wang, Meihong Cai, Xiaohuan Luo, Wei Xia, Song Quan
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3580
    1502
    PDF: 929
    HTML: 42
  • Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

    Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li
    17-05-2023
    https://doi.org/10.4081/ejh.2023.3612
    1256
    PDF: 870
    Supplementary: 76
    HTML: 19
  • Molecules involved in the sperm interaction in the human uterine tube: a histochemical and immunohistochemical approach

    David Cajas , Emanuel Guajardo, Sergio Jara-Rosales, Claudio Nuñez, Renato Vargas, Victor Carriel, Antonio Campos, Luis Milla, Pedro Orihuela, Carlos Godoy-Guzman
    13-04-2023
    https://doi.org/10.4081/ejh.2023.3513
    1219
    PDF: 672
    HTML: 39
  • Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea

    Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong
    01-09-2023
    https://doi.org/10.4081/ejh.2023.3704
    1090
    PDF: 787
    HTML: 20
  • Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

    Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3639
    1147
    PDF: 680
    HTML: 21
  • Expression of nestin, parvalbumin and otoferlin during cochlear development in the mouse: an immunofluorescence study

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Shujuan Yang
    22-09-2025
    https://doi.org/10.4081/ejh.2025.4242
    503
    PDF: 383
    Supplementary: 29
    HTML: 7
  • Expression of hyaluronan synthase 3 in deformed human temporomandibular joint discs: in vivo and in vitro studies

    T. Matsumoto, M. Inayama, I. Tojyo, N. Kiga, S. Fujita
    e50
    15-12-2010
    https://doi.org/10.4081/ejh.2010.e50
    1638
    PDF: 662
    HTML: 1275
  • Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1

    S. Iachettini, R. Valaperta, A. Marchesi, A. Perfetti, G. Cuomo, B. Fossati, L. Vaienti, E. Costa, G. Meola, R. Cardani
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2562
    1906
    PDF: 905
    HTML: 391
  • Molecules implicated in glucose homeostasis are differentially expressed in the trachea of lean and obese Zucker rats

    F. Merigo, F. Boschi, C. Lasconi, D. Benati, A. Sbarbati
    01-02-2016
    https://doi.org/10.4081/ejh.2016.2557
    2612
    PDF: 735
    HTML: 713
  • Detection of cancer clones in human colorectal adenoma as revealed by increased DNA instability and other bio-markers

    Y Jin, A Sun, S Noriki, Y Imamura, M Fukuda
    1-10
    30-06-2009
    https://doi.org/10.4081/1005
    542
    PDF: 396
  • Immunohistochemical and ultrastructural study of the lamellae of oocytes in atretic follicles in relation to different processes of cell death

    M.L. Escobar, O.M. Echeverría, G. García, R. Ortíz, G.H. Vázquez-Nin
    12-08-2015
    https://doi.org/10.4081/ejh.2015.2535
    1829
    PDF: 652
    HTML: 904
  • Lysosomal labelling with mouse anti-human LAMP-1 antibody (green) shows that the autofluorescent material (red) is located within LAMP-1 positive vesicles (arrow heads)

    Autofluorescence in freshly isolated adult human liver sinusoidal cells

    Anett Kristin Larsen, Jaione Simón-Santamaría, Kjetil Elvevold, Bo Göran Ericzon, Kim Erlend Mortensen, Peter McCourt, Bård Smedsrød, Karen Kristine Sørensen
    13-12-2021
    https://doi.org/10.4081/ejh.2021.3337
    2259
    PDF: 894
    HTML: 62
  • MiR-550a-3p restores damaged vascular smooth muscle cells by inhibiting thrombomodulin in an in vitro atherosclerosis model

    Shiyuan Chen, Longfei Zhang, Benchi Feng, Wei Wang, Delang Liu, Xinyu Zhao, Chaowen Yu, Xiaogao Wang, Yong Gao
    19-07-2022
    https://doi.org/10.4081/ejh.2022.3429
    1145
    PDF: 610
    Supplementary: 125
    HTML: 33
  • Muc5ac mucin expression during rat skin development

    V. Ferretti, Á. Segal-Eiras, C.G. Barbeito, M.V. Croce
    20-02-2015
    https://doi.org/10.4081/ejh.2015.2462
    2411
    PDF: 804
    HTML: 717
  • Histochemistry as a unique approach for investigating normal and osteoarthritic cartilage

    G. Musumeci, P. Castrogiovanni, V. Mazzone, M.A. Szychlinska, S. Castorina, C. Loreto
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2371
    3567
    PDF: 1120
    HTML: 3155
  • miR-29a-3p enhances the radiosensitivity of oral squamous cell carcinoma cells by inhibiting ADAM12

    Cuihong Jiang, Feng Liu , Shuai Xiao, Lili He, Wenqiong Wu, Qi Zhao
    27-09-2021
    https://doi.org/10.4081/ejh.2021.3295
    1274
    PDF: 779
    HTML: 24
  • Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas

    J. Waisberg, T.R. Theodoro, L.L. Matos, F.B. Orlandi, R.L. Serrano, G.T. Saba, M.A.S. Pinhal
    17-02-2016
    https://doi.org/10.4081/ejh.2016.2590
    2341
    PDF: 753
    HTML: 452
  • Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

    R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2547
    1793
    PDF: 1033
    HTML: 352
  • HACAT CELLS AS A 2D EXPERIMENTAL DIFFERENTIATING MODEL TO ANALYZE THE EARLY BIOLOGICAL EFFECTS INDUCED BY A PSORIATIC PROINFLAMMATORY MICROENVIRONMENT: CELL PROLIFERATION, DIFFERENTIATION AND FERROPTOSIS F. Riva1, S. Recalcati2, E. Gammella2, D. Daluiso1, F. Prignano3, E. Donetti2 | 1Dept. Public Health, Experimental and Forensic Medicine; Histology and Embryology Unit, University of Pavia, Pavia, Italy; 2Dept. Biomedical Sciences for Health, University of Milan, Milan, Italy; 3Dept. Health Sciences, Section of Dermatology, University of Florence, Florence, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4293
    166
  • P36 | BIOLOGICAL ROLE OF DNA G-QUADRUPLEX DURING LIVER REGENERATION AFTER PARTIAL HEPATECTOMY T. Ishizuka, K. M. Aung, T. Kubota, B. Lkham-Erdene, K. Kai, Y. Hishikawa | Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4358
    154
  • Investigating conversion of endplate chondrocytes induced by intermittent cyclic mechanical unconfined compression in three-dimensional cultures

    H.G. Xu, W. Zhang, Q. Zheng, Y.F. Yu, L.F. Deng, H. Wang, P. Liu, M. Zhang
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2415
    1676
    PDF: 759
    HTML: 370
  • microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

    Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu
    10-05-2022
    https://doi.org/10.4081/ejh.2022.3333
    1614
    PDF: 866
    HTML: 27
  • Elemental analysis of histological specimens: a method to unmask nano asbestos fibers

    M. Scimeca, A. Pietroiusti, F. Milano, L. Anemona, A. Orlandi, L.T. Marsella, E. Bonanno
    01-02-2016
    https://doi.org/10.4081/ejh.2016.2573
    2400
    PDF: 1586
    HTML: 401
  • DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

    Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3413
    1189
    PDF: 616
    Supplementary: 91
    HTML: 20
  • Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment

    R.J. Bułdak, M. Skonieczna, Ł. Bułdak, N. Matysiak, Ł. Mielańczyk, G. Wyrobiec, M. Kukla, M. Michalski, K. Żwirska-Korczala
    12-09-2014
    https://doi.org/10.4081/ejh.2014.2408
    2047
    PDF: 777
    HTML: 572
  • Subcellular distribution and expression of cofilin and ezrin in human colon adenocarcinoma cell lines with different metastatic potential

    D. Nowak, A. J. Mazur, A. Popow-Woźniak, A. Radwańska, H. G. Mannherz, M. Malicka-Błaszkiewicz
    e14
    13-04-2010
    https://doi.org/10.4081/ejh.2010.e14
    1665
    PDF: 617
    HTML: 2671
  • Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells in vitro

    Xilin Ge, Caoxin Huang, Wenting Chen, Chen Yang, Wenfang Huang, Jia Li, Shuyu Yang
    25-11-2024
    https://doi.org/10.4081/ejh.2024.4140
    1825
    PDF: 550
    HTML: 25
  • Analysis of ERK3 intracellular localization: dynamic distribution during mitosis and apoptosis

    F. Aredia, M. Malatesta, P. Veneroni, M.G. Bottone
    01-12-2015
    https://doi.org/10.4081/ejh.2015.2571
    2328
    PDF: 751
    HTML: 762
  • Expression of immediate-early genes in the inferior colliculus and auditory cortex in salicylate-induced tinnitus in rat

    S.S. Hu, L. Mei, J.Y. Chen, Z.W. Huang, H. Wu
    12-03-2014
    https://doi.org/10.4081/ejh.2014.2294
    3590
    PDF: 889
    HTML: 627
  • Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

    Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye
    30-09-2021
    https://doi.org/10.4081/ejh.2021.3224
    3340
    PDF: 1837
    HTML: 37
  • A histological procedure to study fungal infection in the wax moth Galleria mellonella

    F. Perdoni, M. Falleni, D. Tosi, D, Cirasola, S. Romagnoli, P. Braidotti, E. Clementi, G. Bulfamante, E. Borghi
    23-09-2014
    https://doi.org/10.4081/ejh.2014.2428
    3440
    PDF: 1500
    HTML: 2405
  • Activation of Hedgehog pathway by circEEF2/miR-625-5p/TRPM2 axis promotes prostate cancer cell proliferation through mitochondrial stress

    ChenHui Zhu, LiJuan Lin, ChangQing Huang, ZhiHui Wu
    11-11-2024
    https://doi.org/10.4081/ejh.2024.4063
    1487
    PDF: 442
    HTML: 11
  • SCHWANN CELLS BEHAVIOR ON SMART ELECTROCONDUCTIVE BIOMATERIALS FOR PERIPHERAL NERVE REGENERATION Paravizzini G1,2, Sandu E1, Fregnan F1,2, Shirosaki Y3 and Raimondo S1,2 | 1Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, Turin, Italy; 2Cavalieri Ottolenghi Neuroscience Institute, University of Turin, Regione Gonzole 10, Orbassano, Turin, Italy; 3Faculty of Engineering, Kyushu Institute of Technology, 1-1 Sensui-cho, Tobata-ku, Kitakyushu-shi, Fukuoka, Japan

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4506
    225
  • Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

    Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou
    02-12-2021
    https://doi.org/10.4081/ejh.2021.3331
    2457
    PDF: 1411
    HTML: 36
  • Inhibition of fibrous adhesion formation in the temporomandibular joint of tenascin-C knockout mice

    Y. Shinohara, K. Okamoto, Y. Goh, N. Kiga, I. Tojyo, S. Fujita
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2337
    2797
    PDF: 916
    HTML: 475
  • Parkia pendula lectin as histochemistry marker for meningothelial tumour

    EIC Beltrão, PL Medeiros, OG Rodrigues, J Figueredo-Silva, MM Valença, LCBB Coelho, LB Carvalho
    139-142
    26-06-2009
    https://doi.org/10.4081/819
    841
    PDF: 939
  • miRNA-877-5p inhibits malignant progression of prostate cancer by directly targeting SSFA2

    Wanchun Wang, Jun Yi, Degang Dong, Wenli Mao, Xuanyu Wang, Zhangren Yan
    20-09-2021
    https://doi.org/10.4081/ejh.2021.3243
    1311
    PDF: 629
    HTML: 35
  • P42 | PANCREATIC CANCER STEM CELLS AND FUNCTIONAL CHARACTERIZATION OF MIR-216A-5P G. Fenu1, C.G. Lison2, F. Etzi3, A. Pisano3, C. Farace3, A. Sabalic3, D. Tutedde3, J.A. Marchal4, R. Madeddu5 | 1Department of Biomedical Science, University of Sassari, 07100 Sassari, Italy; 2Instituto de Investigación Biosanitaria ibs.GRANADA, University Hospitals of Granada-University of Granada, Granada, Spain; 3Department of Biomedical Science, University of Sassari, Sassari, Italy; 4Instituto de Investigación Biosanitaria ibs. GRANADA, University Hospitals of Granada-University of Granada, Granada, Spain; 5Department of Biomedical Science, University of Sassari, Sassari, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4364
    159
  • Biological aggressiveness evaluation in prostate carcinomas: immunohistochemical analysis of PCNA and p53 in a series of Gleason 6 (3+3) adenocarcinomas

    F Cappello, A Palma, A Martorana
    129-132
    26-06-2009
    https://doi.org/10.4081/817
    962
    PDF: 498
  • THE ESTABLISHMENT OF A HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED IN VITRO MODEL TO STUDY DIABETIC PERIPHERAL NEUROPATHY Rando S1,2, Muratori L1,2, Contato A2,3, Lorenzati M2,3, Dotta S2,3, Marvaldi L2,3, Buffo A2,3 and Raimondo S1,2 | 1Department of Clinical and Biological Sciences, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi (NICO), Turin, Italy; 3Department of Neuroscience “Rita Levi Montalcini” University of Turin, Turin, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4509
    214
  • Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

    Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang
    01-09-2025
    https://doi.org/10.4081/ejh.2025.4217
    451
    PDF: 162
    HTML: 6
  • P49 | DEVELOPMENT OF AN INJECTABLE AND SELFASSEMBLING SCAFFOLD FOR THE DIRECT DELIVERY OF CARDIAC EXTRACELLULAR MATRIX AND CARDIAC PROGENITOR CELLS A. Menini1, V. Romano1, A. M. Sacco1, D. Nurzynska2, G. Ricci3, C. Amarelli4, C. Castaldo1, F. Di Meglio1 | 1Department of Public Health, University of Naples «Federico II», Naples, Italy; 2Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi; 3Department of Experimental Medicine, University of Campania «Luigi Vanvitelli», Naples, Italy; 4Department of Cardiac Surgery and Transplants, Monaldi Hospital, Naples, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4371
    229
  • High temperature requirement A1, transforming growth factor beta1, phosphoSmad2 and Ki67 in eutopic and ectopic endometrium of women with endometriosis

    G. Goteri, E. Altobelli, G. Tossetta, A. Zizzi, C. Avellini, C. Licini, T. Lorenzi, M. Castellucci, A. Ciavattini, D. Marzioni
    09-12-2015
    https://doi.org/10.4081/ejh.2015.2570
    2576
    PDF: 789
    HTML: 409
  • Contribution of intestinal smooth muscle to Crohn's disease fibrogenesis

    C. Severi, R. Sferra, A. Scirocco, A. Vetuschi, N. Pallotta, A. Pronio, R. Caronna, G. Di Rocco, E. Gaudio, E. Corazziari, P. Onori
    17-12-2014
    https://doi.org/10.4081/ejh.2014.2457
    2847
    PDF: 1112
    HTML: 434
  • Detection of cancer clones in human gastric adenoma by increased DNA-instability and other biomarkers

    A Sun, S Noriki, Y Imamura, M Fukuda
    111-122
    26-06-2009
    https://doi.org/10.4081/815
    737
    PDF: 632
  • Vitamin D and vitamin D receptor in patients with ophthalmic pterygium

    Cristina Maxia, Daniela Murtas, Michela Corrias, Ignazio Zucca, Luigi Minerba, Franca Piras, Cristiana Marinelli, Maria Teresa Perra
    30-10-2017
    https://doi.org/10.4081/ejh.2017.2837
    1869
    PDF: 976
    HTML: 71
  • NADPH-d activity in rat thymus after the application of retinoid acid

    F. Dorko, T. Špakovská, K. Lovasová, P. Patlevič, D. Kluchová
    e7
    08-02-2012
    https://doi.org/10.4081/ejh.2012.e7
    1400
    PDF: 511
    HTML: 1280
  • New light in flavin autofluorescence

    A.C. Croce, G. Bottiroli
    10-11-2015
    https://doi.org/10.4081/ejh.2015.2576
    2235
    PDF: 938
    HTML: 348
  • Visualizing endocytotic pathways at transmission electron microscopy via diaminobenzidine photo-oxidation by a fluorescent cell-membrane dye

    S. Grecchi, M. Malatesta
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2449
    2454
    PDF: 962
    Supplementary: 273
    HTML: 710
  • Transgenic expression of dentin phosphoprotein inhibits skeletal development

    H. Zhang, P. Liu, S. Wang, C. Liu, P. Jani, Y. Lu, C. Qin
    11-03-2016
    https://doi.org/10.4081/ejh.2016.2587
    1722
    PDF: 654
    HTML: 600
  • Site-directed mutagenesis, in vivo electroporation and mass spectrometry in search for determinants of the subcellular targeting of Rab7b paralogue in the model eukaryote Paramecium octaurelia

    E. Wyroba, P. Kwaśniak, K. Miller, K. Kobyłecki, M. Osińska
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2612
    1773
    PDF: 838
    HTML: 336
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2244
    PDF: 658
    HTML: 807
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European Journal of Histochemistry

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