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The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis

Andrea Ferrigno, Clarissa Berardo, Laura Giuseppina Di Pasqua, Marta Cagna, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti

10-11-2020

https://doi.org/10.4081/ejh.2020.3175

1939

PDF: 995

Supplementary: 199

HTML: 33
Next-generation nutritional biomarkers to guide better health care

CarloAlberto Redi

19-04-2016

https://doi.org/10.4081/ejh.2016.2666

1375

PDF: 737

HTML: 109
Immunolocalization of endocan during the endothelial-mesenchymal transition process

L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez

e13

01-06-2011

https://doi.org/10.4081/ejh.2011.e13

1471

PDF: 587

HTML: 1359
20 | REPRODUCTIVE DYNAMICS AND PHYSIOLOGICAL CONDITION IN DIFFERENT SIZE CLASSES OF COMMON SOLE (SOLEA SOLEA) FROM THE NORTH-CENTRAL ADRIATIC SEA G. Chemello¹, L. Tortora¹, C. Santoni¹, E. Giorgini¹, S. Colella², G. Gioacchini¹ | ¹Dept. of Life and Environmental Science, Polytechnic University of Marche, Italy; ²National Research Council (CNR), Institute for Marine Biological Resources and Biotechnology (IRBIM), Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4638

63

PDF: 35
TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti¹, M. C. Gagliani², G. Bellese², M. Crippa³, A. Abbona⁴, M. Paccagnella⁴, P. Arnaldi⁵, M. C. Merlano⁶, O. Garrone⁷, A.M. Porcelli⁸, M. Matteoli¹, P. Falletta⁹, P. Castagnola¹⁰, K. Cortese² | ¹IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; ²DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; ³Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; ⁴Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; ⁵IRCCS Ospedale Policlinico San Martino, Genova, Italy; ⁶Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; ⁷Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; ⁸FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; ⁹Vita-Salute San Raffaele University, Milan, Italy; ¹⁰IRCCS Ospedale Policlinico San Martino, Genova, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4305

332
Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang

11-05-2023

https://doi.org/10.4081/ejh.2023.3653

1330

PDF: 698

HTML: 43
Defense and protection mechanisms in lung exposed to asbestiform fiber: the role of macrophage migration inhibitory factor and heme oxygenase-1

Carla Loreto, Rosario Caltabiano, Adriana Carol Eleonora Graziano, Sergio Castorina, Claudia Lombardo, Vera Filetti, Ermanno Vitale, Giuseppe Rapisarda, Venera Cardile, Caterina Ledda, Venerando Rapisarda

16-04-2020

https://doi.org/10.4081/ejh.2020.3073

1435

PDF: 851

HTML: 23
Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway

Y. Zhang, J. Wang, X. Cheng, B. Yi, X. Zhang, Q. Li

13-04-2015

https://doi.org/10.4081/ejh.2015.2467

4515

PDF: 1664

HTML: 898
In vitro reparative dentin: a biochemical and morphological study

G. Teti, V. Salvatore, A. Ruggeri, L. Manzoli, M. Gesi, G. Orsini, M. Falconi

e23

06-08-2013

https://doi.org/10.4081/ejh.2013.e23

3334

PDF: 879

HTML: 941
Transfer of Fas (CD95) protein from the cell surface to the surface of polystyrene beads coated with anti-Fas antibody clone CH-11

H. Sawai, N. Domae

e8

04-02-2010

https://doi.org/10.4081/ejh.2010.e8

1417

PDF: 503

HTML: 1411
Curculigoside inhibits osteoarthritis via the regulation of NLRP3 pathway

Xufei Wang, Yinlian Liu, Yongnian Zhou, Yang Zhou, Yueping Li

13-12-2023

https://doi.org/10.4081/ejh.2023.3896

1503

PDF: 712

HTML: 29
Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi

23-06-2022

https://doi.org/10.4081/ejh.2022.3377

1845

PDF: 975

HTML: 27
Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma

Lulu Le, Ji Luo, Haifang Wu, Ling Chen, Xiaoli Tang, Fen Fu

30-03-2021

https://doi.org/10.4081/ejh.2021.3226

2126

PDF: 898

Supplementary: 204

HTML: 32
Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

16-12-2016

https://doi.org/10.4081/ejh.2016.2711

2671

PDF: 1158

HTML: 313
Analysis of extracellular superoxide dismutase and Akt in ascending aortic aneurysm with tricuspid or bicuspid aortic valve

A. Arcucci, M.R. Ruocco, F. Albano, G. Granato, V. Romano, G. Corso, C. Bancone, E. De Vendittis, A. Della Corte, S. Montagnani

18-07-2014

https://doi.org/10.4081/ejh.2014.2383

2318

PDF: 2247

HTML: 351
Celecoxib treatment does not alter recruitment and activation of osteoclasts in the initial phase of experimental tooth movement

E.P. Carvalho-Filho, A.C. Stabile, E. Ervolino, M.B.S. Stuani, M.M. Iyomasa, M.J.A. Rocha

e43

08-10-2012

https://doi.org/10.4081/ejh.2012.e43

1650

PDF: 724

HTML: 437
69 | ALCL3 TREATMENTS INDUCED MORPHOLOGICAL AND MICROSCOPICAL ALTERATIONS IN PELOPHYLAX LESSONAE EMBRYOS D. Semeraro¹, G. Scillitani¹, D. Mentino¹, M.V. Guglielmi², R. Rossi³, M. Mastrodonato¹ | ¹Dept. Biosciences, Biotechnology and Environment (DBBA), University of Bari Aldo Moro, Italy; ²National Interuniversity Consortium for Marine Sciences (CoNISMa), Rome, Italy; ³Dept. of Pecision and Regenerative Medicine and Ionian Area (DIMEPRE-J), University of Bari Aldo Moro, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4687

66

PDF: 33
Immunohistochemical analysis of YB-1 expression in the developing mouse eye

Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass

03-11-2025

https://doi.org/10.4081/ejh.2025.4244

1669

PDF: 275

HTML: 32
Galunisertib enhances chimeric antigen receptor-modified T cell function

Zhixiong Wang, Qian Liu, Na Risu, Jiayu Fu, Yan Zou, Jiaxing Tang, Long Li, Hui Liu, Guomin Zhou, Xuekai Zhu

19-06-2020

https://doi.org/10.4081/ejh.2020.3122

2117

PDF: 1125

Supplementary: 181

HTML: 20
VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas

Ana Silvia Corlan, Anca Maria Cîmpean, Eugen Melnic, Marius Raica, Simona Sarb

05-03-2019

https://doi.org/10.4081/ejh.2019.3010

1702

PDF: 833

HTML: 24
Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone

26-10-2015

https://doi.org/10.4081/ejh.2015.2547

1904

PDF: 1096

HTML: 361
Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

C. Pellicciari

e51

16-12-2010

https://doi.org/10.4081/ejh.2010.e51

1566

PDF: 771

HTML: 3899
52 | EFFECTS OF DIETARY FRUCTOSE ON DUODENAL MUCIN GLYCOSYLATION AND MUCUS PRODUCTION IN MICE FED A HIGH-FAT DIET D. Mentino¹, A. Provera², C. Vecchio², A. Antonioli², A.N. Sheferaw², N. Taldone¹, R. Vitale³, C. Passamonti⁴, S. Fensore⁵, F. Prodam², S. Sutti², M. Mastrodonato^1|6, M. F. Faienza³ | ¹Department of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, Italy; ²Department of Health Sciences, University of Piemonte Orientale, Novara, Italy; ³ Department of Mathematics, University of Luxembourg, Belval Esch-sur-Alzette, Luxembourg; ⁴Department of Socio-Economic, Managerial and Statistical Studies, University of Chieti-Pescara, 3Pediatric Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Italy; ⁶National Research Council of Italy (CNR) - Water Research Institute (IRSA),Taranto, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4670

90

PDF: 36
PO54 | FATTY INFILTRATION AND POTENTIAL ADIPOGENIC SHIFT OF SKELETAL MUSCLE CELLS: MULTIPARAMETRIC HISTOLOGICAL ANALYSIS OF MYOSTEATOSIS L. Morello¹, G. Stati¹, V. Giansante¹, S. Lattanzio¹, P. Cerritelli¹, D. Bruni¹, S. Cinti², R. Di Pietro^1,3,4 | ¹Department of Medicine and Aging Sciences, “G. d’ Annunzio” University of Chieti-Pescara, Chieti, Italy; ²Department of Experimental and Clinical Medicine, Center of Obesity, Polytechnic University of Marche, Ancona, Italy; ³StemTeCh Group, G. d’ Annunzio Foundation, “G. d’ Annunzio” University of Chieti Pescara, Chieti, Italy; ⁴Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA

21-08-2025

https://doi.org/10.4081/ejh.2025.4379

322
Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea

Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong

01-09-2023

https://doi.org/10.4081/ejh.2023.3704

1250

PDF: 1023

HTML: 25
miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

Nan Xu, Ang-Di Li, Li-Li Ji, Yao Ye, Zhen-Yu Wang, Lei Tong

03-05-2019

https://doi.org/10.4081/ejh.2019.3008

2964

PDF: 1234

HTML: 22
Characterizing the activation of the Wnt signaling pathway in hilar cholangiocarcinoma using a tissue microarray approach

W. Chen, J. Liang, L. Huang, J. Cai, Y. Lei, J. Lai, L. Liang, K. Zhang

09-02-2016

https://doi.org/10.4081/ejh.2016.2536

1924

PDF: 885

HTML: 345
Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

V.N. Karavana, H. Gakiopoulou, E.A. Lianos

15-04-2014

https://doi.org/10.4081/ejh.2014.2308

2252

PDF: 963

HTML: 648
Upregulation of cardiac NO/NOS system during short-term hypoxia and the subsequent reoxygenation period

A. Rus, M.L. Del Moral, F. Molina, M.A. Peinado

e17

17-05-2011

https://doi.org/10.4081/ejh.2011.e17

1246

PDF: 563

HTML: 1412
16 | EXTRACELLULAR VESICLES RELEASED BY CUMULUS CELLS CONTRIBUTE TO THE ACQUISITION OF MOUSE OOCYTE’S DEVELOPMENTAL COMPETENCE Giulia Brazzale¹, Mario Zanoni¹, Valeria Merico¹, Giulia Fiorentino¹, Paola Rebuzzini¹, Andrea Fantinato¹, Margherita Isernia¹, Sergio Comincini¹, Danilo Cimadomo^1|2, Maurizio Zuccotti¹ | ¹Dept. of Biology and Biotechnology, University of Pavia, Italy; ²IVIRMA Global Research Alliance, IVIRMA Italia, Rome, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4634

149

PDF: 33
P01 | PUTATIVE EFFECTS OF THE HYDROGEL-STEM CELL-MELATONIN COMBINATION WITH OR WITHOUT A SCAFFOLD TO TREAT THIOACETAMIDE-INDUCED LIVER DEGENERATION IN RAT G. Ozgun¹, D. Yucel², M. Kolgazi³, S. Ozer⁴, N. Tozun⁵, S. Arbak⁶ | ¹Dept of Medical Biotechnology, Institute of health sciences, Acibadem Univ, Istanbul, Türkiye; ²Dept. of Histology and Embryology, School of Medicine, Acibadem Univ, Istanbul, Türkiye; ³Dept. of Physiology, School of Medicine, Acibadem Univ., Istanbul, Türkiye; ⁴Animal Application and Research Center, Acibadem Univ. Istanbul, Türkiye; ⁵Dept. of Gastroenterology, School of Medicine, Acibadem Univ., Istanbul, Türkiye; ⁶Dept. of Histology and Embryology, School of Medicine, Acibadem Univ., Istanbul, Türkiye

21-08-2025

https://doi.org/10.4081/ejh.2025.4321

211
Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou

02-12-2021

https://doi.org/10.4081/ejh.2021.3331

2663

PDF: 1525

HTML: 40
Expression of E-cadherin, Ki-67, and p53 in urinary bladder cancer in relation to progression, survival, and recurrence

Stanislav Ziaran, Stefan Harsanyi, Katarina Bevizova, Zuzana Varchulova Novakova, Branislav Trebaticky, Peter Bujdak, Stefan Galbavy, Lubos Danisovic

26-03-2020

https://doi.org/10.4081/ejh.2020.3098

1608

PDF: 868

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Damaged muscle fibers might masquerade as hybrid fibers – a cautionary note on immunophenotyping mouse muscle with mouse monoclonal antibodies

Morium Begam, Joseph A. Roche

24-07-2018

https://doi.org/10.4081/ejh.2018.2896

1875

PDF: 674

Supplementary: 314

HTML: 24
Differential expression of KCNQ1 K+ channel in tubular cells of frog kidney

S. Ä†iroviÄ‡, J. MarkoviÄ‡-Lipkovski, J. TodoroviÄ‡, J. NeÅ¡oviÄ‡-OstojiÄ‡, M. JoviÄ‡, S. IliÄ‡, S. TatiÄ‡, D. ÄŒemerikiÄ‡

e7

08-02-2010

https://doi.org/10.4081/ejh.2010.e7

1720

PDF: 510

HTML: 3638
Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra

21-06-2022

https://doi.org/10.4081/ejh.2022.3391

3993

PDF: 1957

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Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

25-08-2017

https://doi.org/10.4081/ejh.2017.2826

3158

PDF: 1330

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67 | DYNAMICS AND INTRACELLULAR TRAFFICKING OF M2R-DUALSTERIC AGONIST COMPLEX INTO GLIOBLASTOMA CELLS G. Scanavino¹, C. Metelli¹, L. Sileo¹, C. Dallanoce², Matera², AM. Tata¹ | ¹Dept. of Biology and Biotechnology, University of Rome “Sapienza”, Italy; ²Dept. of Pharmaceutical Sciences, University of Milan, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4685

90

PDF: 28
Effects of artificial light with different spectral compositions on refractive development and matrix metalloproteinase 2 and tissue inhibitor of metalloproteinases 2 expression in the sclerae of juvenile guinea pigs

Jianbao Yuan, Linfang Li, Yi Fan, Xinyu Xu, Xiaoqiong Huang, Jiayu Shi, Chuanwei Zhang, Lixin Shi, Yuliang Wang

27-06-2024

https://doi.org/10.4081/ejh.2024.3982

1810

PDF: 579

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Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui

15-02-2022

https://doi.org/10.4081/ejh.2022.3316

1926

PDF: 764

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Visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis

Hai-rong Fu, Xiao-shan Li, Yong-hui Zhang, Bin-bin Feng, Lian-hong Pan

07-09-2020

https://doi.org/10.4081/ejh.2020.3131

1341

PDF: 968

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KiSS1 inhibits growth and invasion of osteosarcoma cells through inhibition of the MAPK pathway

Y. Zhang, Y.J. Tang, Z.H. Li, F. Pan, K. Huang, G.H. Xu

e30

29-10-2013

https://doi.org/10.4081/ejh.2013.e30

2877

PDF: 751

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40 | PREIMPLANTATION EMBRYO MORPHOLOGICAL FEATURES AS NON-INVASIVE MARKERS OF DEVELOPMENT TO BLASTOCYST M. Isernia^1|7, A. Fantinato^1|7, L. Corso^2|7, E. Kayar², G. Fiorentino¹, G. Nicora², M. Meseguer³, M. Taggi⁴, F. Innocenti⁴, G. Coticchio⁴, A. Vaiarelli⁵, L. Rienzi^4|6, R. Bellazzi², M. Zuccotti¹, D. Cimadomo^1|4 | ¹Dept. of Biology and Biotechnology, University of Pavia, Italy; ²Dept. of Electrical, Computer and Biomedical Engineering, University of Pavia, Italy; ³IVIRMA Global Research Alliance, IVI Valencia, Spain; ⁴IVIRMA Global Research Alliance, IVIRMA Italia, Italy; ⁵IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Italy; ⁶Dept. of Biomolecular Sciences, University of Urbino, Italy; ⁷these authors contributed equally

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4658

105

PDF: 33
P72 | A SWAB NEGATIVE PATIENT AFTER SARS-COV-2 INFECTION DISPLAYS INCREASE OF VEGF AND FIBRONECTIN ASSOCIATED WITH ALTERATIONS OF INTERCELLULAR JUNCTIONS C. Simioni¹, J.M. Sanz², R. Gafà³, G. Cenacchi⁴, S. Occhionorelli³, R. Rizzo⁵, D. Bortolotti⁵, A. Passaro³, L.M. Neri³ | ¹Department of Life Sciences and Biotechnology, University of Ferrara, Italy; ²Department of Chemical, Pharmaceutical and Agricultural, Sciences, University of Ferrara, Italy; ³Department of Translational Medicine, University of Ferrara, Italy; ⁴Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Italy; ⁵Department of Environmental and Prevention Sciences, University of Ferrara, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4397

306
Long noncoding RNA H19 accelerates tenogenic differentiation by modulating miR-140-5p/VEGFA signaling

You-Jie Liu, Hua-Jun Wang, Zhao-Wen Xue, Lek-Hang Cheang, Man-Seng Tam, Ri-Wang Li, Jie-Ruo Li, Hui-Ge Hou, Xiao-Fei Zheng

07-09-2021

https://doi.org/10.4081/ejh.2021.3297

1888

PDF: 978

Supplementary: 181

HTML: 28
Maxillary sinus augmentation procedures through equine-derived biomaterial or calvaria autologous bone: immunohistochemical evaluation of OPG/RANKL in humans

S. TetÃ¨, R. Vinci, V.L. Zizzari, S. Zara, V. La Scala, A. Cataldi, E. Gherlone, A. Piattelli

e10

27-02-2013

https://doi.org/10.4081/ejh.2013.e10

1459

PDF: 882

HTML: 628
Immunohistochemical identification of resistin in the uterus of ewes subjected to different diets: Preliminary results

Cecilia Dall'Aglio, Paola Scocco, Margherita Maranesi, Linda Petrucci, Gabriele Acuti, Elena De Felice, Francesca Mercati

03-05-2019

https://doi.org/10.4081/ejh.2019.3020

1799

PDF: 1330

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Molecules implicated in glucose homeostasis are differentially expressed in the trachea of lean and obese Zucker rats

F. Merigo, F. Boschi, C. Lasconi, D. Benati, A. Sbarbati

01-02-2016

https://doi.org/10.4081/ejh.2016.2557

2763

PDF: 789

HTML: 721
Immunolocalization of NGF and its receptors in ovarian surface epithelium of the wild ground squirrel during the breeding and nonbreeding seasons

L. Bao, Q. Li, Y. Liu, B. Li, X. Sheng, Y. Han, Q. Weng

09-05-2014

https://doi.org/10.4081/ejh.2014.2363

1943

PDF: 1014

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Establishment and biological characteristics of a Jingning chicken embryonic fibroblast bank

C. Bai, D. Wang, C. Li, D. Jin, C. Li, W. Guan, Y. Ma

e4

29-03-2011

https://doi.org/10.4081/ejh.2011.e4

1942

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08 | HUMAN ADIPOSE STEM CELLS: IMPACT OF DONORS’ AGE ON CELL PROPERTIES AND BEHAVIOUR Ludovica Barone¹, Federica Rossi¹, Federico Tamborini¹, Christina Pagiatakis^1|2, Roberto Papait^1|2, Rosalba Gornati¹ | ¹Dept of Biotechnology and Life Sciences, University of Insubria, Varese, Italy; ²Dept of Cardiovascular Medicine, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4626

192

PDF: 31
P12 | VISUALIZING NUCLEAR ARCHITECTURE DURING MAMMAL ERYTHROPOIESIS C. Casali, M. Cavallo, S. Bellei, A. Diaf, L. Giulini, D. Tunesi, G. Milanesi, M. Biggiogera | Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, Pavia, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4332

208
Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi

22-05-2024

https://doi.org/10.4081/ejh.2024.4033

1295

PDF: 560

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Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability

Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan

07-12-2021

https://doi.org/10.4081/ejh.2021.3352

1807

PDF: 812

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Localization of peripheral autonomic neurons innervating the boar urinary bladder trigone and neurochemical features of the sympathetic component

L. Ragionieri, M. Botti, F. Gazza, C. Sorteni, R. Chiocchetti, P. Clavenzani, L. Bo, R. Panu

e16

06-05-2013

https://doi.org/10.4081/ejh.2013.e16

2538

PDF: 1222

HTML: 1041
Clathrin-dependent endocytosis of membrane-bound RANKL in differentiated osteoclasts

P. Narducci, R. Bortul, R. Bareggi, V. Nicolin

e6

08-03-2010

https://doi.org/10.4081/ejh.2010.e6

1792

PDF: 579

HTML: 6055
Umbilical cord mesenchymal stem cells inhibited inflammation of bronchial epithelial cells by regulating Hedgehog pathway

Qiong Lin, Tianxing Yu, Xiaohua Li, Xin Lin, Yong Fan, Liyu Xu

12-12-2023

https://doi.org/10.4081/ejh.2023.3908

1687

PDF: 537

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New bitongling (NBTL) ameliorates rheumatoid arthritis in rats through inhibiting JAK2/STAT3 signaling pathway

Xiang Li, Yu Xie, An Kang, Yue Wang

17-02-2021

https://doi.org/10.4081/ejh.2021.3202

2554

PDF: 1008

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Oocytes - Maternal Information and Functions

Manuela Monti

18-09-2017

https://doi.org/10.4081/ejh.2017.2849

1623

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Diaminobenzidine photoconversion is a suitable tool for tracking the intracellular location of fluorescently labelled nanoparticles at transmission electron microscopy

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e20

16-04-2012

https://doi.org/10.4081/ejh.2012.20

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64 | UNDERSTANDING PROPERTIES OF NEURAL STEM CELLS ISOLATED FROM A MONOGENIC MOUSE MODEL OF AUTISM EXPRESSING THE R451C NLGN3 MUTATION F. Salvadori, T. Diamanti, L. Santini, S. D’Angelo, F. Serafini, M. Fidaleo, G. Lupo, A. De Jaco, E. Cacci | Department of Biology and Biotechnology “Charles Darwin”, Sapienza University of Rome, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

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Transient receptor potential canonical 3/5 attenuate endothelial damage-induced neointima formation without affecting endothelial cell proliferation

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19-11-2025

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433

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Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally

Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariotti

04-07-2024

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2119

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Hepatocyte growth factor intervention to reduce myocardial injury and improve cardiac function on diabetic myocardial infarction rats

Zaiyong Zhang, Cheng Long, Yufeng Guan, Mingcai Song

30-07-2020

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1434

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Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio

e40

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3804

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The tyrosine kinase receptor c-met, its cognate ligand HGF and the tyrosine kinase receptor trasducers STAT3, PI3K and RHO in thyroid nodules associated with Hashimoto's thyroiditis: an immunohistochemical characterization

R. M. Ruggeri, E. Vitarelli, G. Barresi, F. Trimarchi, S. Benvenga, M. Trovato

e24

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Targeting EphA2 suppresses the proliferation, migration and invasion of endometriosis via the AMPK signaling pathway

Chaoyi Yang, Shujun Wang, Mengru Li, Xiangli Pang, Aili Tan

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Antioxidant support to ameliorate the oxaliplatin-dependent microglial alteration: morphological and molecular study

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1500

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Immunolocalization of aromatase P450 in the epididymis of Podarcis sicula and Rattus rattus

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1889

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Premature senescence in primary muscle cultures of myotonic dystrophy type 2 is not associated with p16 induction

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2476

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Restorative effects of camellia oil on the skin-barrier function in a model of DNCB-induced atopic dermatitis

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21-01-2025

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4849

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Effect of carboplatin injection on Bcl-2 protein expression and apoptosis induction in Raji cells

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2168

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Autophagy precedes apoptosis during degeneration of the Kölliker’s organ in the development of rat cochlea

Shule Hou, Jiarui Chen, Jun Yang

05-06-2019

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Decreased expression of Met during differentiation in rat lung

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1679

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Supplementary: 334

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13 | MULTI-OMICS DISSECTION OF TRANSCRIPTIONAL AND EPIGENETIC REMODELING DURING CARDIAC AGING Daniele Bonisolo¹, Simone Serio², Christina Pagiatakis^1|2, Rosalba Gornati¹, Giovanni Bernardini¹, Roberto Papait^1|2 | ¹Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy; ²Department of Cardiovascular Medicine, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4631

182

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P14 | THE ROLE OF CHROMATIN REORGANIZATION IN HYPOXIA ADAPTATION M. Cavallo¹, C. Casali¹, L. Giulini¹, A. Dia¹, D. Tunesi¹, G. Milanesi¹, G. Mazzini², M. Biggiogera¹ | ¹Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, Pavia; Italy; ²Institute of Molecular Genetics, National Research Council (IGMCNR), Pavia, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4334

202
Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye

30-09-2021

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3750

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Sarcoglycan complex in masseter and sternocleidomastoid muscles of baboons: an immunohistochemical study

G. Cutroneo, A. Centofanti, F. Speciale, G. Rizzo, A. Favaloro, G. Santoro, D. Bruschetta, D. Milardi, A. Micali, D. Di Mauro, G. Vermiglio, G. Anastasi, F. Trimarchi

05-06-2015

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2130

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Poly (ADP-ribose) polymerase 1 protein expression in normal and neoplastic prostatic tissue

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e13

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2986

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miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

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1576

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Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

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1850

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P24 | NUTRACEUTICAL-MEDIATED EFFECTS IN THE MODULATION OF INFLAMMATORY PROCESSES IN AN IN VITRO MODEL OF HUMAN ENDOMETRIAL STROMAL CELLS L. Pietrobelli¹, V.C. Divincenzo¹, L. Sileo¹, G. Scanavino¹, E. Vicini², L. Campagnolo³, V. Corsetti⁴, A.M. Tata¹ | ¹Dept. of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome, Italy; ²Dept. of SAIMAL, Section of Histology, Sapienza University of Rome, Italy; ³Dept. of Biomedicine and Prevention, University of Rome Tor Vergata, Italy; ⁴Institute of Translational Pharmacology (IFT)-CNR, Rome, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

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51

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The hematopoietic stem cells supportive megakaryocytes as shapers of the bone marrow niche

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1032

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CCL18 promotes endometriosis by increasing endometrial cell migration and neuroangiogenesis

Yangying Peng, Shaojie Ding, Ping Xu, Xueyan Zhang, Jianzhang Wang, Tiantian Li, Liyun Liao, Xinmei Zhang

06-08-2024

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1080

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Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

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17-05-2023

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1600

PDF: 951

Supplementary: 106

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Effects mediated by the α7 nicotinic acetylcholine receptor on cell proliferation and migration in rat adipose-derived stem cells

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Expression of Caveolin-1 in tongue squamous cell carcinoma by quantum dots

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e20

14-04-2010

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Expression profile of the zinc transporter ZnT3 in taste cells of rat circumvallate papillae and its role in zinc release, a potential mechanism for taste stimulation

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1361

PDF: 754

Supplementary: 191

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Vitamin D and vitamin D receptor in patients with ophthalmic pterygium

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2010

PDF: 1031

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Lectin-like, oxidized low-density lipoprotein receptor-1-deficient mice show resistance to age-related knee osteoarthritis

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14-02-2017

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3065

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Specific association of growth-associated protein 43 with calcium release units in skeletal muscles of lower vertebrates

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2248

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Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer

J. Ning, J. Zhang, W. Liu, Y. Lang, Y. Xue, S. Xu

e46

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MITOCHONDRIAL DYSFUNCTION AS A KEY FACTOR OF MOTOR NEURON DEGENERATION: INSIGHTS FROM AMYOTROPHIC LATERAL SCLEROSIS CELLULAR MODELS Scimia N¹, Carletti RM², Rasà MD¹, Ferrari D³, Boido M¹ and Stanga S¹ | ¹Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; ²Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; ³Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

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1906

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Supplementary Figure: 102

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Immunohistochemical expression and clinicopathological assessment of PD-1, PD-L1, NY-ESO-1, and MAGE-A4 expression in highly aggressive soft tissue sarcomas

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Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas

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Evidence that muscle cells do not express the histidine-rich glycoprotein associated with AMP deaminase but can internalise the plasma protein

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1629

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28 | 3D MORPHO-FUNCTIONAL RECONSTRUCTION OF THE PREPUBERTAL MOUSE OVARY COMBINING NANO-COMPUTED TOMOGRAPHY AND CONFOCAL IMAGING A. Fantinato^1|4, G. Fiorentino^1|4, A. Parrilli², G. Brazzale¹, V. Merico¹, P. Rebuzzini¹, D. Cimadomo^1|3, S. Garagna¹, M. Zuccotti¹ | ¹Dept. of Biology and Biotechnology, University of Pavia, Italy; ²Empa-Swiss Federal Laboratories for Materials Science and Technology, Switzerland; ³IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Italy; ⁴Equal contribution

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

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66

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P34 | ADJUDIN-INDUCED MODEL IN RATS REVEALS HIPPO SIGNALING PATHWAY ACTIVITY IN THE TESTIS İ. İnanç¹, O. Bender², A. Atalay², E. Erdemli¹ | ¹Ankara University, Faculty of Medicine, Department of Histology and Embryology, Ankara, Türkiye; ²Ankara University, Biotechnology Institute, Ankara, Türkiye

21-08-2025

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1843

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