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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Expression of nestin, parvalbumin and otoferlin during cochlear development in the mouse: an immunofluorescence study

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Shujuan Yang
    22-09-2025
    https://doi.org/10.4081/ejh.2025.4242
    506
    PDF: 387
    Supplementary: 29
    HTML: 7
  • Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

    Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi
    22-05-2024
    https://doi.org/10.4081/ejh.2024.4033
    1085
    PDF: 464
    HTML: 13
  • Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

    Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou
    02-12-2021
    https://doi.org/10.4081/ejh.2021.3331
    2458
    PDF: 1412
    HTML: 36
  • Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

    Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani
    25-08-2017
    https://doi.org/10.4081/ejh.2017.2826
    3007
    PDF: 1252
    HTML: 136
  • Immunoreactivities of PPARγ2, leptin and leptin receptor in oviduct of Chinese brown frog during breeding period and pre-hibernation

    Y. Liu, J. Weng, S. Huang, Y. Shen, X. Sheng, Y. Han, M. Xu, Q. Weng
    09-09-2014
    https://doi.org/10.4081/ejh.2014.2422
    1975
    PDF: 744
    HTML: 280
  • Diaminobenzidine photoconversion is a suitable tool for tracking the intracellular location of fluorescently labelled nanoparticles at transmission electron microscopy

    M. Malatesta, M. Giagnacovo, M. Costanzo, B. Conti, I. Genta, R. Dorati, V. Galimberti, M. Biggiogera, C. Zancanaro
    e20
    16-04-2012
    https://doi.org/10.4081/ejh.2012.20
    1732
    PDF: 936
    HTML: 4342
  • Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

    Jiapei Lv, Wang Yanting, Shan Wei
    08-11-2023
    https://doi.org/10.4081/ejh.2023.3867
    1887
    PDF: 917
    HTML: 43
  • Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier

    Elena Pompili, Viviana Ciraci, Stefano Leone, Valerio De Franchis, Pietro Familiari, Roberto Matassa, Giuseppe Familiari, Ada Maria Tata, Lorenzo Fumagalli, Cinzia Fabrizi
    30-03-2020
    https://doi.org/10.4081/ejh.2020.3109
    1980
    PDF: 877
    HTML: 30
  • Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

    J. Feng, S. Ge, L. Zhang, H. Che, C. Liang
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2711
    2548
    PDF: 965
    HTML: 299
  • Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

    G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio
    e40
    04-12-2013
    https://doi.org/10.4081/ejh.2013.e40
    3628
    PDF: 962
    HTML: 626
  • Expression of Caveolin-1 in tongue squamous cell carcinoma by quantum dots

    J. Xue, H. Chen, L. Diao, X. Chen, D. Xia
    e20
    14-04-2010
    https://doi.org/10.4081/ejh.2010.e20
    1864
    PDF: 606
    HTML: 1573
  • Transient receptor potential canonical 3/5 attenuate endothelial damage-induced neointima formation without affecting endothelial cell proliferation

    Wenjun Zeng, Bei Liu, Lixia Yang, Ruiwei Guo
    19-11-2025
    https://doi.org/10.4081/ejh.2025.4311
    331
    PDF: 168
    HTML: 12
  • Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer

    J. Ning, J. Zhang, W. Liu, Y. Lang, Y. Xue, S. Xu
    e46
    30-11-2012
    https://doi.org/10.4081/ejh.2012.e46
    2430
    PDF: 705
    HTML: 509
  • P38 | THE ROLE OF SPEXIN IN COLORECTAL CANCER J. Kiezun1, J. Godlewski1, M. Kiezun2, M. Gudelska1, K. Kisielewska1, A. E. Kowalczyk1, B. E. Krazinski1 | 1Department of Anatomy and Histology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland; 2Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Poland

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4360
    173
  • Lectin-like, oxidized low-density lipoprotein receptor-1-deficient mice show resistance to age-related knee osteoarthritis

    Kazuhiko Hashimoto, Yutaka Oda, Fumihisa Nakamura, Ryosuke Kakinoki, Masao Akagi
    14-02-2017
    https://doi.org/10.4081/ejh.2017.2762
    2905
    PDF: 920
    HTML: 241
  • Specific association of growth-associated protein 43 with calcium release units in skeletal muscles of lower vertebrates

    G.A. Caprara, S. Perni, C. Morabito, M.A. Mariggiò, S. Guarnieri
    05-12-2014
    https://doi.org/10.4081/ejh.2014.2453
    2136
    PDF: 820
    HTML: 493
  • The expression of Sirtuins 1 and 4 in peripheral blood leukocytes from patients with type 2 diabetes

    R. Song, W. Xu, Y. Chen, Z. Li, Y. Zeng, Y. Fu
    e10
    21-03-2011
    https://doi.org/10.4081/ejh.2011.e10
    1933
    PDF: 629
    HTML: 926
  • STANDARDIZING LIGHT SHEET IMAGING AND 3D IMAGE ANALYSIS FOR WHOLE BRAIN VASCULAR NET QUANTIFICATION Zanella L1, Moretti M1, Quadalti C2, Giardino L1,3,4, Calzà L2,3,4, Baldassarro VA1,4 and Lorenzini L1,4 | 1Department of Veterinary Medical Science, University of Bologna, Ozzano dell’Emilia, Bologna, Italy; 2Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy; 3IRET Foundation, Ozzano dell’Emilia, Bologna, Italy; 4Interdepartmental Centre for Industrial Research in Health Sciences and Technology ICIR-HST, University of Bologna, Ozzano dell’Emilia, Bologna, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4461
    282
  • miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

    Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4161
    1361
    PDF: 418
    HTML: 24
  • MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

    Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3426
    1393
    PDF: 786
    HTML: 25
  • Sertoli Cells - Methods and Protocols

    CarloAlberto Redi
    17-01-2019
    https://doi.org/10.4081/ejh.2019.3014
    1007
    PDF: 518
    HTML: 12
  • Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis

    F. Rappa, E. Unti, P. Baiamonte, F. Cappello, N. Scibetta
    e20
    28-06-2013
    https://doi.org/10.4081/ejh.2013.e20
    2835
    PDF: 668
    HTML: 343
  • TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti1, M. C. Gagliani2, G. Bellese2, M. Crippa3, A. Abbona4, M. Paccagnella4, P. Arnaldi5, M. C. Merlano6, O. Garrone7, A.M. Porcelli8, M. Matteoli1, P. Falletta9, P. Castagnola10, K. Cortese2 | 1IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; 2DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; 3Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; 4Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; 5IRCCS Ospedale Policlinico San Martino, Genova, Italy; 6Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; 7Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 8FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; 9Vita-Salute San Raffaele University, Milan, Italy; 10IRCCS Ospedale Policlinico San Martino, Genova, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4305
    255
  • Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

    Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan
    13-05-2024
    https://doi.org/10.4081/ejh.2024.3917
    1731
    PDF: 640
    HTML: 31
  • Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway

    Y. Zhang, J. Wang, X. Cheng, B. Yi, X. Zhang, Q. Li
    13-04-2015
    https://doi.org/10.4081/ejh.2015.2467
    3427
    PDF: 1520
    HTML: 886
  • Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

    Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3391
    3339
    PDF: 1852
    HTML: 48
  • A new method for the direct tracking of in vivo lignin nanocapsules in Eragrostis tef (Poaceae) tissues

    Sara Falsini, Corrado Tani, Silvia Schiff, Cristina Gonnelli, Ilaria Clemente, Sandra Ristori, Alessio Papini
    26-03-2020
    https://doi.org/10.4081/ejh.2020.3112
    1344
    PDF: 623
    HTML: 16
  • KiSS1 inhibits growth and invasion of osteosarcoma cells through inhibition of the MAPK pathway

    Y. Zhang, Y.J. Tang, Z.H. Li, F. Pan, K. Huang, G.H. Xu
    e30
    29-10-2013
    https://doi.org/10.4081/ejh.2013.e30
    2766
    PDF: 616
    HTML: 313
  • Developmental expression of calretinin in the mouse cochlea

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Xuefang Jiang
    06-11-2024
    https://doi.org/10.4081/ejh.2024.4137
    1546
    PDF: 457
    HTML: 8
  • AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in autophagy-induced astrocytoma cells

    L. Fassina, G. Magenes, A. Inzaghi, S. Palumbo, G. Allavena, C. Miracco, L. Pirtoli, M. Biggiogera, S. Comincini
    e44
    11-10-2012
    https://doi.org/10.4081/ejh.2012.e44
    1982
    PDF: 959
    Supplementary Figures: 298
    Supplementary Table: 218
    HTML: 499
  • PO54 | FATTY INFILTRATION AND POTENTIAL ADIPOGENIC SHIFT OF SKELETAL MUSCLE CELLS: MULTIPARAMETRIC HISTOLOGICAL ANALYSIS OF MYOSTEATOSIS L. Morello1, G. Stati1, V. Giansante1, S. Lattanzio1, P. Cerritelli1, D. Bruni1, S. Cinti2, R. Di Pietro1,3,4 | 1Department of Medicine and Aging Sciences, “G. d’ Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Experimental and Clinical Medicine, Center of Obesity, Polytechnic University of Marche, Ancona, Italy; 3StemTeCh Group, G. d’ Annunzio Foundation, “G. d’ Annunzio” University of Chieti Pescara, Chieti, Italy; 4Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4379
    242
  • Expression profile of the zinc transporter ZnT3 in taste cells of rat circumvallate papillae and its role in zinc release, a potential mechanism for taste stimulation

    Kentaro Nishida, Saho Bansho, Akiko Ikukawa, Teruyo Kubota, Akihiro Ohishi, Kazuki Nagasawa
    10-11-2022
    https://doi.org/10.4081/ejh.2022.3534
    1255
    PDF: 695
    Supplementary: 152
    HTML: 34
  • Antioxidant support to ameliorate the oxaliplatin-dependent microglial alteration: morphological and molecular study

    Jacopo J.V. Branca, Donatello Carrino, Ferdinando Paternostro, Massimo Gulisano, Matteo Becatti, Lorenzo Di Cesare Mannelli, Alessandra Pacini
    10-11-2021
    https://doi.org/10.4081/ejh.2021.3285
    1407
    PDF: 749
    HTML: 13
  • Immunolocalization of NGF and its receptors in ovarian surface epithelium of the wild ground squirrel during the breeding and nonbreeding seasons

    L. Bao, Q. Li, Y. Liu, B. Li, X. Sheng, Y. Han, Q. Weng
    09-05-2014
    https://doi.org/10.4081/ejh.2014.2363
    1858
    PDF: 930
    HTML: 517
  • Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

    Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
    17-04-2025
    https://doi.org/10.4081/ejh.2025.4176
    1241
    PDF: 518
    Supplementary: 84
    HTML: 43
  • Cell Migration - Methods and Protocols

    Manuela Monti
    17-01-2019
    https://doi.org/10.4081/ejh.2019.3013
    1000
    PDF: 563
    HTML: 14
  • Characterizing the activation of the Wnt signaling pathway in hilar cholangiocarcinoma using a tissue microarray approach

    W. Chen, J. Liang, L. Huang, J. Cai, Y. Lei, J. Lai, L. Liang, K. Zhang
    09-02-2016
    https://doi.org/10.4081/ejh.2016.2536
    1794
    PDF: 829
    HTML: 336
  • Poly (ADP-ribose) polymerase 1 protein expression in normal and neoplastic prostatic tissue

    M. Salemi, A. Galia, F. Fraggetta, C. La Corte, P. Pepe, S. La Vignera, G. Improta, P. Bosco, A.E. Calogero
    e13
    15-04-2013
    https://doi.org/10.4081/ejh.2013.e13
    2824
    PDF: 3233
    HTML: 228
  • P01 | PUTATIVE EFFECTS OF THE HYDROGEL-STEM CELL-MELATONIN COMBINATION WITH OR WITHOUT A SCAFFOLD TO TREAT THIOACETAMIDE-INDUCED LIVER DEGENERATION IN RAT G. Ozgun1, D. Yucel2, M. Kolgazi3, S. Ozer4, N. Tozun5, S. Arbak6 | 1Dept of Medical Biotechnology, Institute of health sciences, Acibadem Univ, Istanbul, Türkiye; 2Dept. of Histology and Embryology, School of Medicine, Acibadem Univ, Istanbul, Türkiye; 3Dept. of Physiology, School of Medicine, Acibadem Univ., Istanbul, Türkiye; 4Animal Application and Research Center, Acibadem Univ. Istanbul, Türkiye; 5Dept. of Gastroenterology, School of Medicine, Acibadem Univ., Istanbul, Türkiye; 6Dept. of Histology and Embryology, School of Medicine, Acibadem Univ., Istanbul, Türkiye

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4321
    169
  • SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

    Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu
    03-03-2026
    https://doi.org/10.4081/ejh.2026.4530
    364
    PDF: 277
    HTML: 4
  • Targeting EphA2 suppresses the proliferation, migration and invasion of endometriosis via the AMPK signaling pathway

    Chaoyi Yang, Shujun Wang, Mengru Li, Xiangli Pang, Aili Tan
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4168
    482
    PDF: 279
    HTML: 12
  • Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi
    23-06-2022
    https://doi.org/10.4081/ejh.2022.3377
    1623
    PDF: 834
    HTML: 24
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European Journal of Histochemistry

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