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P70 | TRICHOSANTHIN TARGETS WNT/NF-KB PATHWAYS TO ATTENUATE PSORIATIC INFLAMMATION AND KERATINOCYTE HYPERPROLIFERATION K. Wang1, W. Li1, Z. Ying1, C. Li2, O. Sha1 | 1Department of Anatomy and Histology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen, China; 2Department of Anatomy, Shantou University Medical College, Shantou, China
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73 | PROTECTIVE ROLE FOR OLEOYLETHANOLAMIDE IN THE HUMAN BRAIN: EFFECTS ON THE MODULATION OF NEUROINFLAMMATION AND INSULIN RESISTANCE IN HUMAN ASTROCYTES Lucia Sileo1, Giulia Scanavino1, Silvana Gaetani2, Ada MariaTata1 | 1Dept. of Biology and Biotechnologies "Charles Darwin", University of Rome "Sapienza", Rome, Italy; 2Dept. of Physiology and Pharmacology “Vittorio Erspamer”, University of Rome "Sapienza", Rome, Italy
142PDF: 87 -
15 | BEYOND SURVIVAL: INNATE IMMUNE READOUTS IN ZEBRAFISH FOR ADVANCED BIOMATERIALS ASSESSMENT. C. Bragato, P. Bonfanti, A. Colombo, M. Gualtieri, P. Mantecca | Dept. of Earth and Environmental Sciences, University of Milano-Bicocca, Italy
263PDF: 101 -
KAEMPFEROL TARGETS LIPID BALANCE, ENDOCANNABINOID PATHWAYS, AND PPAR-α IN THE RAT CEREBRAL CORTEX AFTER TRANSIENT BILATERAL COMMON CAROTID ARTERY OCCLUSION AND REPERFUSION Serra MP#, Carta G#, Murru E, Boi M, Manca C, Lai Y, Cabboi M, Carta A, Banni S* and Quartu M* | Department of Biomedical Sciences, University of Cagliari, Italy #equal contribution; *co-seniorship
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ASTROCYTE DYSFUNCTION IN AUTOSOMAL DOMINANT LEUKODYSTROPHY (ADLD): INSIGHTS FROM 2D AND 3D IN VITRO SYSTEMS AND EX VIVO CEREBROSPINAL FLUID METABOLOMICS F.D. Koufi1, V. Righi2, A. Mucci3, I. Rusciano1, S. Mongiorgi1, M. Shin4, Y. Kosodo4, I. Cani5, P. Cortelli6, E. Giorgio7, G. Ramazzotti1, L. Manzoli1, S. Ratti1 | 1 Cellular Signaling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Department of Life Quality Studies, University of Bologna, Campus of Rimini, Rimini, Italy; 3Department of Geological and Chemical Sciences, University of Modena and Reggio Emilia, Modena, Italy; 4Korea Brain Research Institute (KBRI), Daegu, Republic of Korea; 5Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 6IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; 7Department of Molecular Medicine, University of Pavia, Pavia, Italy; Medical Genetics Unit, IRCCS Mondino Foundation, Pavia, Italy.
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Interindividual variability in the expression of surfactant protein A and B in the human lung during development
2209PDF: 864Supplementary: 299HTML: 404 -
Subcutaneous adipose tissue classification
4306PDF: 1509HTML: 2738 -
P82 | PROINFLAMMATORY BONE MARROW NICHES AND NEUTROPHIL ACTIVATION ARE ASSOCIATED WITH TIGIT EXPRESSION IN MULTIPLE MYELOMA V. Velardi1, F. Arciprete1, V. Tomarchio2, G. Vivacqua1, M.A. Tafuri2, M. Di Cecca2, L. Rigacci2, A. Crescenzi3, R. Rana1, O. Annibali2, M. Zingariello1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Unit of Hematology, Stem Cell Transplantation, University Hospital Campus Bio-Medico Rome, Italy; 3Department of Radiological, Oncological, and Pathological Sciences, Sapienza University of Rome, Rome, Italy
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Downregulation of GMPS inhibited the proliferation of hepatocellular cancer cells via the regulation of STAT3/c-Myc pathway
251PDF: 270Supplementary: 63HTML: 21 -
PRENATAL N-ACETYL-CYSTEINE PREVENTS NEURONAL, EMOTIONAL AND METABOLIC IMPAIRMENTS IN AN ANIMAL MODEL OF ADVERSE EXPERIENCES Cirulli F | Center for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy
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Optimization of the autophagy measurement in a human cell line and primary cells by flow cytometry
2281PDF: 1324Supplementary: 233HTML: 56 -
47 | SYNERGISTIC LUNG TOXICITY OF PM2.5 AND ENNIATIN B1 IN A CO-CULTURE MODEL S. Marchetti1, F. Caloni2, P. Mantecca1, M. Gualtieri1 | 1POLARIS Research Centre, Dept. of Earth and Environmental Sciences, University of Milano-Bicocca, Italy; 2Dept. of Environmental Science and Policy, Università degli Studi di Milano, Italy
146PDF: 80 -
P59 | IMMUNOHISTOCHEMISTRY ANALYSIS TO DETECT A MOLECULAR SIGNATURE IN INTERVERTEBRAL DISC DEGENERATION L. Penolazzi1, R. Nadalini1, C. Sief1, E. Lambertini2, C. Angelini3, R. Piva1 | 1Department of Neurosciences and rehabilitation, University of Ferrara, Italy; 2Laboratorio Centralizzato di ricerca preclinica, University of Ferrara, Italy; 3Department of Translational Medicine, University of Ferrara, Italy
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Long noncoding RNA H19 accelerates tenogenic differentiation by modulating miR-140-5p/VEGFA signaling
1998PDF: 1064Supplementary: 207HTML: 44 -
P01 | BET PROTEIN INHIBITION ATTENUATES MICROGLIAL ACTIVATION AND OXIDATIVE STRESS IN A CELLULAR MODEL OF PARKINSON’S DISEASE E. Bisesto1, D. Pensabene1, M. Colardo1, M. Varone1, M. Segatto1 | 1Dept. of Biosciences and territory, University of Molise, Pesche (IS), Italy
146PDF: 73 -
SHORT-TERM EXPOSURE TO PARTICULATE MATTER TRIGGERS SELECTIVE MOLECULAR AND BEHAVIORAL ALTERATIONS IN A MOUSE MODEL OF MULTIPLE SCLEROSIS Bonato M1,2, Montarolo F1,2, Cerrato V1,2, Parolisi R1,2, Abbadessa G3, Caudana M3, Di Cintio N1,2, De Francia S3, Bertolotto A2,4, Buffo A1,2, and Boda E1,2 | 1Dept. of Neuroscience Rita Levi Montalcini, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Orbassano (Turin), Italy; 3Department of Clinical and Biological Sciences, University of Turin, Orbassano (Turin), Italy; 4Koelliker Hospital, Turin, Italy
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24 | ADMINISTRATION OF BRANCHED-CHAIN AMINO ACIDS AND DI-ALANINE MITIGATES MUSCLE ATROPHY IN A MOUSE MODEL OF CANCER CACHEXIA M. Colardo1, N. Martella1, M. Varone1, D. Pensabene1, G. Caretti2, G. Bianchini3, A. Aramini3, M. Segatto1 | 1Dept. of Biosciences and Territory, University of Molise, Italy; 2Dept. of Biosciences, University of Milan, Italy; 3Research & Early Development, Dompé Farmaceutici S.p.A., L’Aquila, Italy
170PDF: 93 -
3-hydroxi-anthranilic acid is early expressed in stroke
2528PDF: 798HTML: 329 -
P60 | UNDERSTANDING HUMAN INTERVERTEBRAL DISC HOMEOSTASIS: 3D EXPERIMENTAL MODELS L. Penolazzi1, A. Chierici1, R. Nadalini1, E. Lambertini2, C. Nastruzzi3, G. Lisignoli4, C. Manferdini4, G. D’Atri4, R. Piva1 | 1Department of Neurosciences and rehabilitation, University of Ferrara, Italy; 2Laboratorio centralizzato di ricerca preclinica, University of Ferrara, Italy; 3Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Italy; 4Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
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Lectins as versatile tools to explore cellular glycosylation
3218PDF: 1374HTML: 67 -
Immuno- and glyco-histochemistry as a tool to evaluate the oregano supplemented feed effects in pig gut
1944PDF: 933Supplementary: 249HTML: 35 -
77 | TARGETING P75NTR CORRECTS OXIDATIVE AND INFLAMMATORY IMBALANCES IN A CELLULAR MODEL OF RETT SYNDROME M. Varone, M. Colardo, N. Martella, D. Pensabene, E. Bisesto, M. Segatto | Dept of Biosciences and Territory, University of Molise, Pesche, Italy
182PDF: 75 -
THE EFFECT OF ANTIBIOTIC-INDUCED DYSBIOSIS ON PERIPHERAL NERVE REPAIR Pellegrino D1, El Soury M1, Farzin S1, Elmelgy AA1, Muratori L1, Calabrò S2, Ferrocino I3, Ferrero G1, Camandona A1, Haastert- Talini K4, Cescon M2, Gambarotta G1 and Ronchi G1 | 1Department of Clinical and Biological Sciences & Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Torino, Orbassano, (Torino), Italy; 2Department of Molecular Medicine, University of Padova, Padova, Italy; 3Department of Scienze Agrarie, Forestali e Alimentari, DISAFA, University of Torino, Grugliasco, (Torino), Italy; 4Institute of Neuroanatomy and Cell Biology, Hannover Medical School, Carl-Neuberg-Str.1, Hannover, Lower-Saxony, Germany
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39 | ENVIRONMENTAL FACTORS INFLUENCE THE PROTECTIVE EFFICACY OF BRASSICA OLERACEA EXTRACTS ON INTESTINAL AND HEPATIC HOMEOSTASIS IN ZEBRAFISH R. Imperatore1, I. Šola2, E. Coccia1, R. Sciarrillo1, M. Paolucci1 | 1Dept. of Sciences and Technologies, University of Sannio, Benevento, Italy; 2Department of Biology, Faculty of Science, University of Zagreb, Croatia
165PDF: 90 -
23 | BIOFUNCTIONALIZED ELECTROSPUN FIBERS FOR SKIN REGENERATION E. Coccia1, R. Imperatore1, E. Mula1|2, M. Paolucci1 | 1Dept. of Sciences and Technologies, University of Sannio, Benevento, Italy; 2Dept. of Organic and Inorganic Chemistry, University of Alcalà, Alcalà de Henares, Spain
155PDF: 81 -
P65 | (YS) INVESTIGATING THE EFFECTS OF THE SECRETOME FROM HUMAN AMNIOTIC MESENCHYMAL STROMAL CELLS ON INFLAMMASOME ACTIVATION M. Rossi1, M. Magatti2, P. Romele2, E. Vertua2, E. Giuzzi2, S. Farigu2, L. Marelli2, B. Rapuzzi2, S. De Munari2, A. Silini2, O. Parolini3 | 1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, and Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 2Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 3Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy & Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy
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A PILOT STUDY TO INVESTIGATE THE ANTIAGING EFFECTS OF THE OLIVE POMACE BY-PRODUCT ON THE BRAIN OF DROSOPHILA MELANOGASTER Makladissi S1†, Tomassoni D2†*, Nardin T3, Bellitto V2, Cappelli A2, Di Cara F1‡ and Beghelli D2‡ | 1Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada; 2School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, MC, Italy ; 3Chemical Unit Oenological Vines Agri-food - Technology Transfer Centre Foundation Edmund Mach, TN, Italy †These authors equally contributed. ‡These authors share the authorship
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Morphological and ultrastructural analysis of normal, injured and osteoarthritic human knee menisci
2949PDF: 1457Supplementary: 294HTML: 81 -
41 | IMPACT OF POLYETHYLENE MICROPLASTICS ON INTESTINE, OVARY AND BRAIN OF ZEBRAFISH A. La Pietra, A.R. Bianchi, B. Berman, T. Mobilio, A. Chirico, G. Imbimbo, A. De Maio, I. Ferrandino | Dept. of Biology, University of Naples Federico II, Italy
147PDF: 93 -
P37 | THE ROLE OF ACTIN-BINDING PROTEINS IN ENDOMETRIOSIS W. Arendt1, M. Hałas-Wiśniewska1, M. Gagat2, M. Izdebska1 | 1Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; 2Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland
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