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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway

    Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Han
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4093
    2266
    PDF: 595
    HTML: 52
  • Expression of lumican and fibromodulin following interleukin-1 beta stimulation of disc cells of the human temporomandibular joint

    N. Kiga, I. Tojyo, T. Matsumoto, Y. Hiraishi, Y. Shinohara, S. Makino, S. Fujita
    e11
    01-04-2011
    https://doi.org/10.4081/ejh.2011.e11
    1696
    PDF: 725
    HTML: 1905
  • RXRα is upregulated in first trimester endometrial glands of spontaneous abortions unlike LXR and PPARγ

    J. Knabl, A. Vattai, R. Hüttenbrenner, S. Hutter, M. Karsten, U. Jeschke
    02-11-2016
    https://doi.org/10.4081/ejh.2016.2665
    2137
    PDF: 1077
    HTML: 319
  • An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible

    S. Shibata, H. Fukuoka, R. Sato, T. Abe, Y. Suzuki
    e23
    23-05-2012
    https://doi.org/10.4081/ejh.2012.23
    2207
    PDF: 653
    HTML: 5686
  • Radioprotective potential of histamine on rat small intestine and uterus

    E. Carabajal, N. Massari, M. Croci, D. J. Martinel Lamas, J. P. Prestifilippo, R. M. Bergoc, E. S. Rivera, V. A. Medina
    e48
    18-12-2012
    https://doi.org/10.4081/ejh.2012.e48
    1317
    PDF: 718
    HTML: 911
  • Combined lectin- and immuno-histochemistry (CLIH) for applications in cell biology and cancer diagnosis: Analysis of human urothelial carcinomas

    Daša Zupančič, Mateja Erdani Kreft, Igor Sterle, Rok Romih
    01-07-2020
    https://doi.org/10.4081/ejh.2020.3141
    1455
    PDF: 821
    Supplementary: 194
    HTML: 15
  • Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: a clue to enhance endometrial receptivity in recurrent implantation failure

    Haixia Li, Ning Sun, Yaqiao Zhu, Wei Wang, Meihong Cai, Xiaohuan Luo, Wei Xia, Song Quan
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3580
    1624
    PDF: 961
    HTML: 44
  • CCL18 promotes endometriosis by increasing endometrial cell migration and neuroangiogenesis

    Yangying Peng, Shaojie Ding, Ping Xu, Xueyan Zhang, Jianzhang Wang, Tiantian Li, Liyun Liao, Xinmei Zhang
    06-08-2024
    https://doi.org/10.4081/ejh.2024.4052
    1008
    PDF: 700
    HTML: 40
  • Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

    Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan
    11-11-2022
    https://doi.org/10.4081/ejh.2022.3563
    1616
    PDF: 862
    Supplementary: 121
    HTML: 33
  • Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

    Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
    17-04-2025
    https://doi.org/10.4081/ejh.2025.4176
    1353
    PDF: 599
    Supplementary: 109
    HTML: 44
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1497
    PDF: 242
    HTML: 22
  • Non-invasive imaging demonstrates clinical features of ankylosing spondylitis in a rat adjuvant model: a case study

    N. Accart, J. Dawson, F. Kolbinger, I. Kramer, N. Beckmann
    02-11-2016
    https://doi.org/10.4081/ejh.2016.2667
    2331
    PDF: 889
    HTML: 376
  • WT1 expression in the human fetus during development

    R. Ambu, L. Vinci, C. Gerosa, D. Fanni, E. Obinu, A. Faa, V. Fanos
    29-06-2015
    https://doi.org/10.4081/ejh.2015.2499
    2225
    PDF: 841
    HTML: 983
  • LncRNA FBXO18-AS promotes gastric cancer progression by TGF-β1/Smad signaling

    Yiming Zhang, Wanqiong Zheng, Liang Zhang, Yechun Gu, Lihe Zhu, Yingpeng Huang
    20-06-2023
    https://doi.org/10.4081/ejh.2023.3667
    1191
    PDF: 638
    Supplementary: 93
    HTML: 22
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    246
    PDF: 414
    Supplementary: 30
    HTML: 3
  • Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

    Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3653
    1205
    PDF: 618
    HTML: 39
  • Anatomical insights into the proximal aponeurosis of the long head of the biceps femoris

    Carmela Julia Mantecón-Tagarro, Eri Nanizawa, Munekazu Naito, Shun Otsuka, Huub Maas, Yasuo Kawakami
    13-05-2025
    https://doi.org/10.4081/ejh.2025.4165
    902
    PDF: 491
    HTML: 36
  • Analysis of extracellular superoxide dismutase and Akt in ascending aortic aneurysm with tricuspid or bicuspid aortic valve

    A. Arcucci, M.R. Ruocco, F. Albano, G. Granato, V. Romano, G. Corso, C. Bancone, E. De Vendittis, A. Della Corte, S. Montagnani
    18-07-2014
    https://doi.org/10.4081/ejh.2014.2383
    2221
    PDF: 2188
    HTML: 348
  • Decreased expression of Met during differentiation in rat lung

    T. Kato, K. Oka, T. Nakamura, A. Ito
    01-02-2016
    https://doi.org/10.4081/ejh.2016.2575
    1646
    PDF: 763
    Supplementary: 310
    HTML: 276
  • Effect of interleukin-1beta and dehydroepiandrosterone on the expression of lumican and fibromodulin in fibroblast-like synovial cells of the human temporomandibular joint

    K. Okamoto, N. Kiga, Y. Shinohara, I. Tojyo, S. Fujita
    23-02-2015
    https://doi.org/10.4081/ejh.2015.2440
    2432
    PDF: 1115
    HTML: 589
  • High-level detection of gene amplification and chromosome aneuploidy in extracted nuclei from paraffin-embedded tissue of human cancer using FISH: a new approach for retrospective studies

    E Rossi, A Ubiali, P Balzarini, M Cadei, F Alpi, PG Grigolato
    53-58
    29-06-2009
    https://doi.org/10.4081/927
    710
    PDF: 927
  • Assessment of the Selenoprotein M (SELM) over-expression on human hepatocellular carcinoma tissues by immunohistochemistry

    E. Guerriero, M. Accardo, F. Capone, G. Colonna, G. Castello, S. Costantini
    01-12-2014
    https://doi.org/10.4081/ejh.2014.2433
    4008
    PDF: 815
    HTML: 420
  • Morphological and immunohistochemical study of ovarian and tubal dysplasia associated with tamoxifen

    G. Chene, N. Radosevic-Robin, A.S. Tardieu, A. Cayre, I. Raoelfils, P. Dechelotte, J. Dauplat, F. Penault Llorca
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2251
    2381
    PDF: 849
    HTML: 476
  • Histochemical and morpho­metrical study of mouse intestine epithelium after a long term diet containing genetically modified soybean

    S. Battistelli, B. Citterio, B. Baldelli, C. Parlani, M. Malatesta
    e36
    05-08-2010
    https://doi.org/10.4081/ejh.2010.e36
    2186
    PDF: 596
    HTML: 9315
  • Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

    Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno
    15-03-2018
    https://doi.org/10.4081/ejh.2018.2841
    14560
    PDF: 7122
    HTML: 470
  • Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas

    J. Waisberg, T.R. Theodoro, L.L. Matos, F.B. Orlandi, R.L. Serrano, G.T. Saba, M.A.S. Pinhal
    17-02-2016
    https://doi.org/10.4081/ejh.2016.2590
    2404
    PDF: 768
    HTML: 463
  • Interindividual variability in the expression of surfactant protein A and B in the human lung during development

    F. Cau, E. Pisu, C. Gerosa, G. Senes, F. Ronchi, C. Botta, E. Di Felice, F. Uda, V. Marinelli, G. Faa, V. Fanos, C. Moretti, D. Fanni
    26-09-2016
    https://doi.org/10.4081/ejh.2016.2678
    2031
    PDF: 772
    Supplementary: 256
    HTML: 386
  • Correlation of the AKT/mTOR signaling pathway with the clinicopathological features and prognosis of nasopharyngeal carcinoma

    Yan Wang, Jie Sun, Ninghua Yao
    16-11-2021
    https://doi.org/10.4081/ejh.2021.3304
    1675
    PDF: 616
    HTML: 41
  • A new monoclonal antibody against DNA ligase I is a suitable marker of cell proliferation in cultured cell and tissue section samples

    B Vitolo, MR Lidonnici, C Montecucco, A Montecucco
    349-354
    30-06-2009
    https://doi.org/10.4081/962
    985
    PDF: 668
  • Immunohistochemical LRIG3 expression in cervical intraepithelial neoplasia and invasive squamous cell cervical cancer: association with expression of tumor markers, hormones, high-risk HPV-infection, smoking and patient outcome

    A.K. Lindström, D. Hellberg
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2227
    3213
    PDF: 1098
    HTML: 289
  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    344
    PDF: 248
    Raw data: 38
    HTML: 14
  • RANK/RANKL/OPG signaling pathways in necrotic jaw bone from bisphosphonate-treated subjects

    C. Di Nisio, V.L. Zizzari, S. Zara, M. Falconi, G. Teti, G. Tetè, A. Nori, V. Zavaglia, A. Cataldi
    03-02-2015
    https://doi.org/10.4081/ejh.2015.2455
    2811
    PDF: 1147
    HTML: 603
  • alpha2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade

    Michael W.L. Quirino, Amanda P.B. Albuquerque, Maria F.D. de Souza, Antônio F. da Silva Filho, Mário R. Martins, Maira G. da Rocha Pitta, Michelly C. Pereira, Moacyr J.B. de Melo Rêgo
    29-09-2022
    https://doi.org/10.4081/ejh.2022.3330
    1381
    PDF: 721
    Supplementary: 125
    HTML: 30
  • Mena, a new available marker in tumors of salivary glands?

    S. Gurzu, M. Krause, I. Ember, L. Azamfirei, G. Gobel, K. Feher, I. Jung
    e8
    07-02-2012
    https://doi.org/10.4081/ejh.2012.e8
    1372
    PDF: 697
    HTML: 4124
  • The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesions

    L. Pilloni, P. Bianco, E. DiFelice, S. Cabras, M.E. Castellanos, L. Atzori, C. Ferreli, P. Mulas, S. Nemolato, G. Faa
    e20
    07-06-2011
    https://doi.org/10.4081/ejh.2011.e20
    1317
    PDF: 694
    HTML: 9931
  • IMP-3 expression in keratoacanthomas and squamous cell carcinomas of the skin: an immunohistochemical study

    S. Soddu, E. Di Felice, S. Cabras, M.E. Castellanos, L. Atzori, G. Faa, L. Pilloni
    e6
    14-02-2013
    https://doi.org/10.4081/ejh.2013.e6
    1506
    PDF: 743
    HTML: 476
  • Mammaglobin, GATA-binding protein 3 (GATA3), and epithelial growth factor receptor (EGFR) expression in different breast cancer subtypes and their clinical significance

    Xin Kong, Qi Wang, Jie Li, Ming Li, Fusheng Deng, Chuanying Li
    07-04-2022
    https://doi.org/10.4081/ejh.2022.3315
    1584
    PDF: 800
    Supplementary: 153
    HTML: 17
  • Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

    Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang
    29-04-2024
    https://doi.org/10.4081/ejh.2024.4019
    1870
    PDF: 598
    HTML: 23
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2708
    PDF: 836
    HTML: 345
  • Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

    Jun Lin, Liping Jiang, Kun Guo, Ning Feng
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3528
    1986
    PDF: 1205
    Supplementary: 129
    HTML: 37
  • Immunoreactivity and a new staining method of monocarboxylate transporter 1 located in endothelial cells of cerebral vessels of human brain in distinguishing cerebral venules from arterioles

    Yuan Cao, Dong-Hui Ao, Chao Ma, Wen-Ying Qiu, Yi-Cheng Zhu
    01-10-2021
    https://doi.org/10.4081/ejh.2021.3306
    1490
    PDF: 782
    HTML: 25
    Supplementary: 133
  • Histochemical and morphological aspects of fresh frozen bone: a preliminary study

    F.S. De Ponte, G. Cutroneo, R. Falzea, G. Rizzo, L. Catalfamo, A. Favaloro, G. Vermiglio, M. Runci, A. Centofanti, G. Anastasi
    06-12-2016
    https://doi.org/10.4081/ejh.2016.2642
    1533
    PDF: 617
    HTML: 158
  • The fuss over lipo“fussâ€cin: not all autofluorescence is the same

    B. Sainz Jr., I. Miranda-Lorenzo, C. Heeschen
    12-03-2015
    https://doi.org/10.4081/ejh.2015.2512
    2404
    PDF: 896
    HTML: 1329
  • Reliable hexokinase 3 protein detection in human cell lines and primary tissue

    Yasmeen H. Mady, Carmen G. Kalbermatter, Maarij Khan, Anna M. Schläfli, Rina Mehmeti, Inti Zlobec, Lucine Christe, Mario P. Tschan
    12-03-2025
    https://doi.org/10.4081/ejh.2025.4175
    1877
    PDF: 446
    Supplementary: 58
    Uncropped Western blots: 56
    HTML: 12
  • Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

    Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera
    20-04-2022
    https://doi.org/10.4081/ejh.2022.3409
    1774
    PDF: 914
    HTML: 27
  • Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

    Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui
    15-02-2022
    https://doi.org/10.4081/ejh.2022.3316
    1841
    PDF: 737
    HTML: 25
  • Bile duct ligature in young rats: A revisited animal model for biliary atresia

    Matias Garrido, Camila Escobar, Constanza Zamora, Carolina Rejas, Juan Varas, Mario Párraga, Sebastián San Martin, Sandra Montedonico
    13-09-2017
    https://doi.org/10.4081/ejh.2017.2803
    2032
    PDF: 961
    HTML: 153
  • An improved and cost-effective methodology for the reduction of autofluorescence in direct immunofluorescence studies on formalin-fixed paraffin-embedded tissues

    MS Viegas, TC Martins, F Seco, A do Carmo
    59-66
    30-06-2009
    https://doi.org/10.4081/1013
    2114
    PDF: 1687
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    264
    PDF: 211
    HTML: 3
  • Immunohistochemical profile of some neurotransmitters and neurotrophins in the seminiferous tubules of rats treated by lonidamine

    M Artico, E Bronzetti, L Saso, LM Felici, A D'Ambrosio, F Forte, C Grande, F Ortolani
    19-24
    30-06-2009
    https://doi.org/10.4081/1007
    616
    PDF: 498
  • CALRETININ IMMUNOREACTIVITY IN NERVE CELLS OF THE HUMAN MIDBRAIN AND THEIR POTENTIAL ROLE IN NEURODEGENERATIVE DISORDERS Flace P1, Caporusso C2, Galletta D3, Stolfa M2, Cacciola A4,5, Scarcella VS2, Branca JJV6, Gulisano M6, Milardi D7, Gradini R8, Livrea P9 and Marzullo A2 | 1Medical School, University of Bari Aldo Moro, Bari, Italy; 2Department of Precision and Regenerative Medicine and Ionian Area, Pathology Unit, University of Bari Aldo Moro, Bari, Italy; 3Specialization School Neuropsychology, University of Campania Luigi Vanvitelli, Caserta, Italy; 4IRCCS Humanitas Research Hospital, Milan, Italy; 5Department of Biomedical Sciences, Humanotas University, Milan, Italy; 6Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 7Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy; 8Department of Experimental Medicine, Sapienza University, Roma, Italy; 9University of Bari Aldo Moro, Bari, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4491
    218
  • Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

    Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3639
    1228
    PDF: 718
    HTML: 24
  • P23 | CALRETININ IMMUNOREACTIVE NON-TRADITIONAL LARGE NEURONS IN THE GRANULAR LAYER OF THE HUMAN CEREBELLAR CORTEX P. Flace1, M. E. Caringella2, D. Galletta3, G. Santangelo3, C. Caporusso2, M. Stolfa2, A. Cacciola4, J.J.V. Branca5, G. Agazzino2, R. Gradini6, P. Livrea7, A. Marzullo2 | 1Medical School, University of Bari ‘Aldo Moro’, Bari, Italy; 2Section of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari ‘Aldo Moro’, Italy; 3Department of Psychology, Specialization School of Neuropsychology. University of Campania ‘Luigi Vanvitelli’, Caserta, Italy; 4Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy; 5Department of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy; 6Department of Experimental Medicine, Sapienza University, Roma, Italy; 7University of Bari ‘Aldo Moro’, Bari, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4343
    158
  • Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

    Jiapei Lv, Wang Yanting, Shan Wei
    08-11-2023
    https://doi.org/10.4081/ejh.2023.3867
    2005
    PDF: 974
    HTML: 49
  • Lycopersicon esculentum lectin: an effective and versatile endothelial marker of normal and tumoral blood vessels in the central nervous system

    S Mazzetti, S Frigerio, M Gelati, A Salmaggi, L Vitellaro-Zuccarello
    423-428
    29-06-2009
    https://doi.org/10.4081/916
    2195
    PDF: 3224
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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