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Substance P is overexpressed in cervical squamous cell carcinoma and promoted proliferation and invasion of cervical cancer cells in vitro

Ying Wang, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang

31-07-2023

https://doi.org/10.4081/ejh.2023.3746

1154

PDF: 548

HTML: 41
Analysis of ERK3 intracellular localization: dynamic distribution during mitosis and apoptosis

F. Aredia, M. Malatesta, P. Veneroni, M.G. Bottone

01-12-2015

https://doi.org/10.4081/ejh.2015.2571

2553

PDF: 859

HTML: 791
Analysis of extracellular superoxide dismutase and Akt in ascending aortic aneurysm with tricuspid or bicuspid aortic valve

A. Arcucci, M.R. Ruocco, F. Albano, G. Granato, V. Romano, G. Corso, C. Bancone, E. De Vendittis, A. Della Corte, S. Montagnani

18-07-2014

https://doi.org/10.4081/ejh.2014.2383

2457

PDF: 2327

HTML: 372
Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

16-12-2016

https://doi.org/10.4081/ejh.2016.2711

2779

PDF: 1224

HTML: 338
Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou

22-06-2022

https://doi.org/10.4081/ejh.2022.3394

2245

PDF: 1434

HTML: 48
Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei

17-03-2014

https://doi.org/10.4081/ejh.2014.2263

4017

PDF: 1128

HTML: 624
Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps?

Antonella Vetuschi, Simon Pompili, Gian Piero Di Marco, Federico Calvaruso, Enz Iacomino, Lidia Angelosante, Claudio Festuccia, Alessandro Colapietro, Roberta Sferra

23-01-2020

https://doi.org/10.4081/ejh.2020.3079

2289

PDF: 1369

HTML: 33
Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu

11-05-2026

https://doi.org/10.4081/ejh.2026.4557

563

PDF: 998

Supplementary: 68

HTML: 33
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang

01-03-2023

https://doi.org/10.4081/ejh.2023.3648

5330

PDF: 1234

HTML: 68
Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

Jiapei Lv, Wang Yanting, Shan Wei

08-11-2023

https://doi.org/10.4081/ejh.2023.3867

2317

PDF: 1150

HTML: 81
Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRα) signal through MAPK/ERK pathway in human prostate tissues: a morphological and biomolecular study

Sonia Fantone, Giovanni Tossetta, Rodolfo Montironi, Martina Senzacqua , Daniela Marzioni, Roberta Mazzucchelli

19-10-2020

https://doi.org/10.4081/ejh.2020.3147

2296

PDF: 884

HTML: 41
Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin

23-10-2024

https://doi.org/10.4081/ejh.2024.4098

2756

PDF: 621

HTML: 54
Crocin exerts anti-tumor effect in colon cancer cells via repressing the JAK pathway

Hui Yang, Yunlong Zhang, Desheng Zhang, Liping Qian, Tianxing Yang, Xiaocheng Wu

12-09-2023

https://doi.org/10.4081/ejh.2023.3697

1515

PDF: 782

HTML: 34
Neurokinin-1 receptor is highly expressed in cervical cancer and its antagonist induces cervical cancer cell apoptosis

Liyun Guan, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang

11-01-2023

https://doi.org/10.4081/ejh.2023.3570

1654

PDF: 779

HTML: 49
MyD88/ERK/NFkB pathways and pro-inflammatory cytokines release in periodontal ligament stem cells stimulated by Porphyromonas gingivalis

Francesca Diomede, Maria Zingariello, Marcos F.X.B. Cavalcanti, Ilaria Merciaro, Jacopo Pizzicannella, Natalia de Isla, Sergio Caputi, Patrizia Ballerini, Oriana Trubiani

24-05-2017

https://doi.org/10.4081/ejh.2017.2791

3541

PDF: 1482

HTML: 170
Deubiquitinase USP14 is upregulated in Crohn's disease and inhibits the NOD2 pathway mediated inflammatory response in vitro

Mengling Li, Yan Zhao, Jiayi Zhang, Wang Jiang, Siyuan Peng, Jinyue Hu, Yueming Shen

09-09-2024

https://doi.org/10.4081/ejh.2024.4101

1519

PDF: 518

HTML: 36
Erratum - Analysis of extracellular superoxide dismutase and Akt in ascending aortic aneurysm with tricuspid or bicuspid aortic valve

A. Arcucci, M.R. Ruocco, F. Albano, G. Granato, V. Romano, G. Corso, C. Bancone, E. De Vendittis, A. Della Corte, S. Montagnani

26-03-2015

https://doi.org/10.4081/ejh.2015.2517

1594

PDF: 609

HTML: 100
Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li

21-01-2025

https://doi.org/10.4081/ejh.2025.4158

2034

PDF: 695

Supplementary Figure: 136

HTML: 76
Continuous cyclic mechanical tension increases ank expression in endplate chondrocytes through the TGF-Î²1 and p38 pathway

H. Xu, X. Zhang, H. Wang, Y. Zhang, Y. Shi, X. Zhang

e28

25-09-2013

https://doi.org/10.4081/ejh.2013.e28

2496

PDF: 741

HTML: 242
Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio

19-10-2023

https://doi.org/10.4081/ejh.2023.3846

1974

PDF: 756

HTML: 48
Assessment of the Selenoprotein M (SELM) over-expression on human hepatocellular carcinoma tissues by immunohistochemistry

E. Guerriero, M. Accardo, F. Capone, G. Colonna, G. Castello, S. Costantini

01-12-2014

https://doi.org/10.4081/ejh.2014.2433

4442

PDF: 900

HTML: 437
Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon

23-01-2017

https://doi.org/10.4081/ejh.2017.2749

6247

PDF: 1450

HTML: 422
Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu

20-03-2023

https://doi.org/10.4081/ejh.2023.3639

1425

PDF: 851

HTML: 45
TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti¹, M. C. Gagliani², G. Bellese², M. Crippa³, A. Abbona⁴, M. Paccagnella⁴, P. Arnaldi⁵, M. C. Merlano⁶, O. Garrone⁷, A.M. Porcelli⁸, M. Matteoli¹, P. Falletta⁹, P. Castagnola¹⁰, K. Cortese² | ¹IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; ²DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; ³Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; ⁴Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; ⁵IRCCS Ospedale Policlinico San Martino, Genova, Italy; ⁶Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; ⁷Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; ⁸FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; ⁹Vita-Salute San Raffaele University, Milan, Italy; ¹⁰IRCCS Ospedale Policlinico San Martino, Genova, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4305

436
Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway

Y. Zhang, J. Wang, X. Cheng, B. Yi, X. Zhang, Q. Li

13-04-2015

https://doi.org/10.4081/ejh.2015.2467

4663

PDF: 1815

HTML: 921
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng

21-06-2022

https://doi.org/10.4081/ejh.2022.3412

2750

PDF: 1555

HTML: 49
P74 | EXPRESSION OF PISCIDIN, TLR-4, ERK2 AND P-P38 MAPK IN THE ZEBRAFISH GUT EXPOSED TO PCB-126 AND POSSIBLE PROTECTIVE EFFECTS OF GINESTEIN L. Spiccia¹, A. Miller², G.P. Lombardo¹, V. Natale¹, F. Pellicanò¹, S. Marino¹, A. Nunnari¹, A. Migliorato³, E.R. Laurian¹ | ¹Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; ²Department of Veterinary Sciences, University of Messina, Messina, Italy; ³Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, Messina, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4399

354
PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNFα-CX3CR1 pathway

Xilei Li, Zhi Ye, Qulian Guo, E Wang, Yundan Pan

12-03-2021

https://doi.org/10.4081/ejh.2021.3184

2397

PDF: 1016

HTML: 43
Infection with CagA-positive Helicobacter pylori strain containing three EPIYA C phosphorylation sites is associated with more severe gastric lesions in experimentally infected Mongolian gerbils (Meriones unguiculatus)

M. Ferreira JÃºnior, S.A. Batista, P.V.T. Vidigal, A.A.C. Cordeiro, F.M.S. Oliveira, L.O. Prata, A.E.T. Diniz, C.M. Barral, R.C. Barbuto, A.D. Gomes, I.D. AraÃºjo, D.M.M. Queiroz, M.V. Caliari

27-04-2015

https://doi.org/10.4081/ejh.2015.2489

2332

PDF: 894

Supplementary: 366

HTML: 581
Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

Arvis Pauliņš, Anna Junga, Māra Pilmane

10-02-2026

https://doi.org/10.4081/ejh.2026.4438

417

PDF: 539

HTML: 35
Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats

Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng

12-01-2022

https://doi.org/10.4081/ejh.2022.3328

2433

PDF: 1427

HTML: 122
ANIMAL MODELS OF METASTATIC CANCER - ADVANCED IMAGE ANALYSIS FOR DISSECTION OF DRIVING SIGNALING PATHWAYS S. Alberti | University of Messina, Messina, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4287

263
The injury of serotonin on intestinal epithelium cell renewal of weaned diarrhoea mice

Y. Dong, C. Yang, Z. Wang, Z. Qin, J. Cao, Y. Chen

28-12-2016

https://doi.org/10.4081/ejh.2016.2689

2550

PDF: 969

HTML: 822
Investigating conversion of endplate chondrocytes induced by intermittent cyclic mechanical unconfined compression in three-dimensional cultures

H.G. Xu, W. Zhang, Q. Zheng, Y.F. Yu, L.F. Deng, H. Wang, P. Liu, M. Zhang

17-07-2014

https://doi.org/10.4081/ejh.2014.2415

1857

PDF: 1034

HTML: 395
Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li

22-07-2024

https://doi.org/10.4081/ejh.2024.4048

2645

PDF: 1464

HTML: 44
Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway

Li Chu, Suhong Ma, Zhiwei Chen, Wenfu Cao

01-04-2021

https://doi.org/10.4081/ejh.2021.3198

1978

PDF: 1079

HTML: 40
miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen

07-04-2025

https://doi.org/10.4081/ejh.2025.4161

1771

PDF: 577

HTML: 56
TRAIL, DR5 and caspase 3-dependent apoptosis in vessels of diseased human temporomandibular joint disc. An immunohistochemical study

C. Loreto, L. E. Almeida, M.R. Migliore, M. Caltabiano, R. Leonardi

e40

13-09-2010

https://doi.org/10.4081/ejh.2010.e40

2776

PDF: 683

HTML: 1727
E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei

26-05-2025

https://doi.org/10.4081/ejh.2025.4196

1671

PDF: 694

HTML: 46
Downregulation of Williams syndrome transcription factor (WSTF) suppresses glioblastoma cell growth and invasion by inhibiting PI3K/AKT signal pathway

Liyuan Yang, Chunfu Du, Hui Chen, Zhengwen Diao

17-11-2021

https://doi.org/10.4081/ejh.2021.3255

1386

PDF: 737

HTML: 62
Varying effects of EGF, HGF and TGFÎ² on formation of invadopodia and invasiveness of melanoma cell lines of different origin

A. Makowiecka, A. Simiczyjew, D. Nowak, A.J. Mazur

09-12-2016

https://doi.org/10.4081/ejh.2016.2728

2442

PDF: 1057

Supplementary: 330

HTML: 440
Co-transplantation of bone marrow mesenchymal stem cells and monocytes in the brain stem to repair the facial nerve axotomy

Li Wu, Dan Han, Jie Jiang, Xiaojie Xie, Xunran Zhao, Tengfei Ke, Wen Zhao, Liu Liu, Wei Zhao

19-06-2020

https://doi.org/10.4081/ejh.2020.3136

1840

PDF: 880

HTML: 33
Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

V.N. Karavana, H. Gakiopoulou, E.A. Lianos

15-04-2014

https://doi.org/10.4081/ejh.2014.2308

2329

PDF: 1019

HTML: 665
DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu

03-05-2017

https://doi.org/10.4081/ejh.2017.2775

2833

PDF: 1132

HTML: 206
Bovine pericardium membrane, gingival stem cells, and ascorbic acid: a novel team in regenerative medicine

Jacopo Pizzicannella, Guya D. Marconi, Sante D. Pierdomenico, Marcos F.X.B. Cavalcanti, Francesca Diomede, Oriana Trubiani

25-09-2019

https://doi.org/10.4081/ejh.2019.3064

1847

PDF: 921

HTML: 43
Long non-coding RNA WAC antisense RNA 1 mediates hepatitis B virus replication in vitro by reinforcing miR-192-5p/ATG7-induced autophagy

Minkai Cao, Deping Yuan, Hongxiu Jiang, Guanlun Zhou, Chao Chen, Guorong Han

02-09-2022

https://doi.org/10.4081/ejh.2022.3438

1682

PDF: 1037

HTML: 68
01 | OVERCOMING HORMONAL BARRIERS TO CARDIAC REGENERATION G. D’Uva^1|2 | ¹Department of Medical and Surgical Sciences; ²IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4619

390

PDF: 152
Role of Zip1 in the regulation of NPY expression by MLT to promote fracture healing in rats

Junjun Shang, Bin Ma, Guiling Zhu, Penghong Dong, Chan Wang, Xiaochuan Gu, Ying Zi

02-12-2020

https://doi.org/10.4081/ejh.2020.3183

1996

PDF: 872

HTML: 34
MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells

J. Zhang, J. Luo, J. Ni, L. Tang, H.P. Zhang, L. Zhang, J.F. Xu, D. Zheng

18-02-2014

https://doi.org/10.4081/ejh.2014.2262

3697

PDF: 1130

HTML: 362
MODULATION OF EXTRACELLULAR SIGNAL-RELATED KINASE, CYCLIN D1, GLIAL FIBRILLARY ACIDIC PROTEIN, AND VIMENTIN EXPRESSION IN ESTRADIOL-PRETREATED ASTROCYTE CULTURES TREATED WITH COMPETENCE AND PROGRESSION GROWTH FACTORS Barbagallo A¹, Barbagallo F¹, Rapisarda G¹ and Avola R¹ | ¹Department of Biometec (Biochemistry Section), University of Catania, Italy

12-12-2025

https://doi.org/10.4081/ejh.2025.4476

371
STAT3 and SOCS3 expression patterns during murine placenta development

S. San Martin, J. Fitzgerald, M. Weber, M. PÃ¡rraga, T. SÃ¡ez, T.M. Zorn, U.R. Markert

e19

28-06-2013

https://doi.org/10.4081/ejh.2013.e19

3891

PDF: 964

HTML: 337
Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1583

PDF: 817

HTML: 53
Chemotherapy-induced nephrotoxicity was improved by crocin in mouse model

Qichao Yin, Hua Xiong

03-10-2022

https://doi.org/10.4081/ejh.2022.3541

1222

PDF: 767

HTML: 69
Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner

Jana Oswald, Maximilian Büttner, Simon Jasinski-Bergner, Roland Jacobs, Philip Rosenstock, Heike Kielstein

26-01-2018

https://doi.org/10.4081/ejh.2018.2848

3555

PDF: 1305

HTML: 140
CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure

S. Huang, S. Guo, F. Guo, Q. Yang, X. Xiao, M. Murata, S. Ohnishi, S. Kawanishi, N. Ma

e1

14-01-2013

https://doi.org/10.4081/ejh.2013.e1

2299

PDF: 955

HTML: 904
Irisin suppresses PDGF-BB-induced proliferation of vascular smooth muscle cells in vitro by activating AMPK/mTOR-mediated autophagy

Fenqiang Qi, Yuxin Deng, Wei Huang, Yanli Cai, Kelin Hong, Shui Xiang

15-10-2024

https://doi.org/10.4081/ejh.2024.4104

2638

PDF: 746

HTML: 34
Effect of unacylated ghrelin on peripheral nerve regeneration

Giulia Ronchi, Pierluigi Tos, Elia Angelino, Luisa Muratori, Simone Reano, Nicoletta Filigheddu, Andrea Graziani, Stefano Geuna, Stefania Raimondo

04-11-2021

https://doi.org/10.4081/ejh.2021.3287

1914

PDF: 1039

HTML: 31
Three-dimensional apoptotic nuclear behavior analyzed by means of Field Emission in Lens Scanning Electron Microscope

S. Salucci, S. Burattini, E. Falcieri, P. Gobbi

15-09-2015

https://doi.org/10.4081/ejh.2015.2539

1740

PDF: 1080

HTML: 397
Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu

15-06-2026

https://doi.org/10.4081/ejh.2026.4569

301

PDF: 244

HTML: 33
The substance P and neurokinin-1 receptor system in human thyroid cancer: an immunohistochemical study

Inmaculada Isorna, Francisco Esteban, Juan Solanellas, Rafael Coveñas, Miguel Muñoz

28-04-2020

https://doi.org/10.4081/ejh.2020.3117

1511

PDF: 789

HTML: 27
Expression of immediate-early genes in the inferior colliculus and auditory cortex in salicylate-induced tinnitus in rat

S.S. Hu, L. Mei, J.Y. Chen, Z.W. Huang, H. Wu

12-03-2014

https://doi.org/10.4081/ejh.2014.2294

3931

PDF: 1026

HTML: 657
Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun

07-04-2025

https://doi.org/10.4081/ejh.2025.4182

1405

PDF: 835

HTML: 73
High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos

17-02-2022

https://doi.org/10.4081/ejh.2022.3360

2857

PDF: 1118

HTML: 65
Twenty years of histochemistry in the third millennium, browsing the scientific literature

Carlo Pellicciari

29-12-2020

https://doi.org/10.4081/ejh.2020.3213

1529

PDF: 595

HTML: 33
Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

25-08-2017

https://doi.org/10.4081/ejh.2017.2826

3293

PDF: 1410

HTML: 165
Nuclear damages and oxidative stress: new perspectives for laminopathies

G. Lattanzi, S. Marmiroli, A. Facchini, N.M. Maraldi

e45

18-10-2012

https://doi.org/10.4081/ejh.2012.e45

2241

PDF: 1029

HTML: 229
SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang

18-05-2026

https://doi.org/10.4081/ejh.2026.4544

341

PDF: 361

Supplementary: 65

HTML: 26
Erratum - Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng

20-06-2023

https://doi.org/10.4081/ejh.2023.3794

936

PDF: 580

HTML: 35
Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio

e40

04-12-2013

https://doi.org/10.4081/ejh.2013.e40

3899

PDF: 1113

HTML: 653
miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan

07-12-2021

https://doi.org/10.4081/ejh.2021.3237

1904

PDF: 672

HTML: 54
Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang

08-09-2023

https://doi.org/10.4081/ejh.2023.3742

1423

PDF: 556

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Imaging techniques in nanomedical research

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https://doi.org/10.4081/ejh.2020.3151

2251

PDF: 894

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Angiotensin II: immunohistochemical study in Sardinian pterygium

P. Demurtas, M. Corrias, I. Zucca, C. Maxia, F. Piras, P. Sirigu, M.T. Perra

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https://doi.org/10.4081/ejh.2014.2426

2303

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P02 | THE C-C CHEMOKINE-RECEPTOR 2 (CCR2)/CCL2 AXIS PARTICIPATE IN PLATELET FUNCTION IN MYELOFIBROSIS F. Arciprete¹, V. Velardi¹, G. Pozzi², C. Carubbi³, S. Cortellazzi³, A.M. Vannucchi⁴, M. Vitale⁵, R.A. Rana¹, G. Vivacqua¹, E. Masselli³, M. Zingariello¹ | ¹Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; ²Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; ³Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; ⁴Center Research and Innovation of Myeloproliferative Neoplasm, University Hospital Careggi, University of Florence, Florence, Italy; ⁵San Raffaele University, Milano, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4322

422
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https://doi.org/10.4081/ejh.2017.2763

5376

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Seasonal expressions of VEGF and its receptors VEGFR1 and VEGFR2 in the prostate of the wild ground squirrels (Spermophilus dauricus)

Yuchen Yao, Wenqian Xie, Di Chen, Yingying Han, Zhengrong Yuan, Haolin Zhang, Qiang Weng

24-03-2021

https://doi.org/10.4081/ejh.2021.3219

1677

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Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

A.M. SchlÃ¤fli, S. Berezowska, O. Adams, R. Langer, M.P. Tschan

05-05-2015

https://doi.org/10.4081/ejh.2015.2481

9356

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Chronic cypermethrin exposure alters mouse embryonic stem cell growth kinetics, induces Phase II detoxification response and affects pluripotency and differentiation gene expression

Paola Rebuzzini, Cinzia Civello, Edouard Nantia Akono, Lorenzo Fassina, Maurizio Zuccotti, Silvia Garagna

17-02-2020

https://doi.org/10.4081/ejh.2020.3084

1685

PDF: 1155

Supplementary: 237

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Knockdown of RAGE inhibits growth and invasion of gastric cancer cells

X.C. Xu, X. Abuduhadeer, W.B. Zhang, T. Li, H. Gao, Y.H. Wang

e36

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https://doi.org/10.4081/ejh.2013.e36

4522

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MiR-550a-3p restores damaged vascular smooth muscle cells by inhibiting thrombomodulin in an in vitro atherosclerosis model

Shiyuan Chen, Longfei Zhang, Benchi Feng, Wei Wang, Delang Liu, Xinyu Zhao, Chaowen Yu, Xiaogao Wang, Yong Gao

19-07-2022

https://doi.org/10.4081/ejh.2022.3429

1423

PDF: 779

Supplementary: 176

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Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang

29-04-2024

https://doi.org/10.4081/ejh.2024.4019

2178

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Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

26-01-2026

https://doi.org/10.4081/ejh.2026.4422

858

PDF: 480

Supplementary: 87

Original gels: 104

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Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng

03-09-2021

https://doi.org/10.4081/ejh.2021.3264

2240

PDF: 821

Supplementary: 186

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Is there still room for novelty, in histochemical papers?

Carlo Pellicciari

16-12-2016

https://doi.org/10.4081/ejh.2016.2758

3193

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Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao

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https://doi.org/10.4081/ejh.2023.3766

2406

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MicroRNA-22 enhances the differentiation of mouse induced pluripotent stem cells into alveolar epithelial type II cells

Fan Tao, Feng Wang, Weichen Zhang, Yaming Hao

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https://doi.org/10.4081/ejh.2020.3170

1629

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Maternal dietary loads of alpha-tocopherol increase synapse density and glial synaptic coverage in the hippocampus of adult offspring

S. Salucci, P. Ambrogini, D. Lattanzi, M. Betti, P. Gobbi, C. Galati, F. Galli, R. Cuppini, A. Minelli

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https://doi.org/10.4081/ejh.2014.2355

2284

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Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang

01-09-2025

https://doi.org/10.4081/ejh.2025.4217

678

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Characterization of the role of RILP in cell migration

Azzurra Margiotta, Cinzia Progida, Oddmund Bakke, Cecilia Bucci

31-05-2017

https://doi.org/10.4081/ejh.2017.2783

2732

PDF: 1087

Supplementary: 294

Movie 1: 409

Movie 2: 452

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Tripartite motif-containing protein 6 facilitates growth and migration of breast cancer through degradation of STUB1

Chuanchao Wei, Jiayue Wu, Weiyan Liu, Jingfeng Lu, Hongchang Li, Benjun Hai

10-03-2021

https://doi.org/10.4081/ejh.2021.3214

1938

PDF: 981

Supplementary: 210

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alpha2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade

Michael W.L. Quirino, Amanda P.B. Albuquerque, Maria F.D. de Souza, Antônio F. da Silva Filho, Mário R. Martins, Maira G. da Rocha Pitta, Michelly C. Pereira, Moacyr J.B. de Melo Rêgo

29-09-2022

https://doi.org/10.4081/ejh.2022.3330

1719

PDF: 1014

Supplementary: 160

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miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

Nan Xu, Ang-Di Li, Li-Li Ji, Yao Ye, Zhen-Yu Wang, Lei Tong

03-05-2019

https://doi.org/10.4081/ejh.2019.3008

3068

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dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas

Y. Zhang, W.Y. Ye, J.Q. Wang, S.J. Wang, P. Ji, G.Y. Zhou, G.P. Zhao, H.L. Ge, Y. Wang

e29

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https://doi.org/10.4081/ejh.2013.e29

3216

PDF: 957

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Exploring the efficacy of AMACR, ERG, and AR immunostains in prostatic adenocarcinoma and their association with novel grade groups

Mohamed O. Andarawi, Hassan Otifi, Hesham Hassan, Adil A. Yousif , Saadalnour A. Mustafa, Shawgi A. Elsiddig , Asad Ma Babker, Elryah I. Ali , Omer Osman Elhag

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https://doi.org/10.4081/ejh.2025.4172

1546

PDF: 488

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Effects of chronic exposure to bisphenol A in adult female mice on social behavior, vasopressin system, and estrogen membrane receptor (GPER1)

Brigitta Bonaldo, Antonino Casile, Martina Bettarelli, Stefano Gotti, GianCarlo Panzica, Marilena Marraudino

10-11-2021

https://doi.org/10.4081/ejh.2021.3272

2529

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LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu

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https://doi.org/10.4081/ejh.2023.3535

1406

PDF: 808

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NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou

30-06-2025

https://doi.org/10.4081/ejh.2025.4221

1309

PDF: 578

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microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu

10-05-2022

https://doi.org/10.4081/ejh.2022.3333

2522

PDF: 1016

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Evaluation of expression of Toll-Like Receptors 7 and 9, proliferation, and cytoskeletal biomarkers in plaque and guttate psoriasis: A pilot morphological study

Francesca Prignano, Giulia Lombardo, Serena Indino, Federica Ricceri, Laura Cornaghi, Elena B. Donetti

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https://doi.org/10.4081/ejh.2021.3218

1862

PDF: 757

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VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

Meiying Zhang, Min Zhou, Xia Cai, Yan Zhou, Xueling Jiang, Yan Luo, Yue Hu, Rong Qiu, Yanrong Wu, Yuejin Zhang, Yan Xiong

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https://doi.org/10.4081/ejh.2022.3522

2842

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