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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

    Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao
    22-08-2025
    https://doi.org/10.4081/ejh.2025.4230
    326
    PDF: 248
    HTML: 4
  • Immunoreactivity of thymosin beta 4 in human foetal and adult genitourinary tract

    S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, D. Fanni, C. Gerosa, B. Manconi, I. Messana, M. Castagnola, G. Faa
    e43
    13-10-2010
    https://doi.org/10.4081/ejh.2010.e43
    1409
    PDF: 565
    HTML: 948
  • Quantification of morphology of canine circumanal gland tumors: a fractal based study

    I.C. Šoštarić-Zuckermann, K. Severin, M. Huzak, M. Hohšteter, A. Gudan Kurilj, B. Artuković, A. Džaja, Ž. Grabarević
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2609
    1812
    PDF: 697
    HTML: 381
  • LEVERAGING ORGANOID TECHNOLOGIES TO CHARACTERIZE DYNAMIC TUMOR CELL STATES DRIVING TREATMENT RESISTANCE IN PANCREATIC CANCER A. Papargyriou1-6, M. Najajreh1-4, D.P. Cook7, C.H. Maurer1,2, S. Bärthel8, P. Putze8, H.A. Messal9, S.K. Ravichandran1-3, T. Richter10, M. Knolle11, T. Metzler12, A.R. Shastri1,2,3, R. Öllinger13, J. Jasper1,2,3, L. Schmidleitner1,2,3, C.Schneeweis8, H. Ishikawa-Ankerhold14, T. Engleitner13, S. Dobiasch15, I. Heid, M.D. Luecken16, K. Steiger12, G. Kaissis11, J. Van Rheenen9, F.J. Theis10, D. Saur8, R. Rad13, M. Reichert1,2,3,4,5,17,18 | 1Translational Pancreatic Cancer Research Center, Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Germany; 2Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Germany; 3Center for Functional Protein Assemblies, Technical University of Munich, Garching, Germany; 4Center for Organoid Systems (COS), Technical University of Munich, Garching, Germany; 5Bavarian Cancer Research Center (BZKF), Munich, Germany; 6Institute of Stem Cell Research, Helmholtz Center Munich, Neuherberg, Germany; 7University of Ottawa, Faculty of Medicine, Department of Cellular and Molecular Medicine, Ottawa, ON, Canada; 8Chair for Translational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Germany; 9Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands. 10Institute of Computational Biology, Helmholtz Center Munich, Neuherberg, Germany; 11Institute of Diagnostic and Interventional Radiology, Klinikum rechts der Isar München, Technical University of Munich, Germany; 12Comparative Experimental Pathology, Institut für Allgemeine Pathologie und Pathologische Anatomie, School of Medicine, Technical University of Munich, Germany; 13Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technical University of Munich, Germany; 14Department of Medicine I, University Hospital of the LudwigMaximilians-University Munich, Germany; 15Department of Radiation Oncology, Technical University of Munich, Germany; 16Institute of Lung Health and Immunity (LHI), Helmholtz Munich, Comprehensive Pneumology Center (CPC-M), Germany; Member of the German Center for Lung Research (DZL); 17German Cancer Consortium (DKTK), Munich, Germany; 18Munich Institute of Biomedical Engineering (MIBE), Technical University of Munich, Germany

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4289
    245
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2247
    PDF: 662
    HTML: 809
  • Assessing the interactions between nanoparticles and biological barriers in vitro: a new challenge for microscopy techniques in nanomedicine

    Flavia Carton, Manuela Malatesta
    24-11-2022
    https://doi.org/10.4081/ejh.2022.3603
    974
    PDF: 433
    HTML: 19
  • P51 | DECELLULARIZATION OF HUMAN LUNG SCAFFOLD FOR TUMOR MICROENVIRONMENT MODELLING STUDY A. Mileo1, S. Boccia2, E. Del Genio1, R. Pastore1, M. De Falco3, I. Belviso4 | 1Dept. of Medicine and Health Sciences, University of Molise, Campobasso, Italy; 2Dept. of Biology, University of Naples Federico II, Naples, Italy; 3Dept. of Biology, University of Naples Federico II, Naples, Italy; National Institute of Biostructures and Biosystems (INBB), Rome, Italy; 4Dept. of Wellness, Nutrition and Sport, Telematic University Pegaso, Naples, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4373
    225
  • Is there still room for novelty, in histochemical papers?

    Carlo Pellicciari
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2758
    2724
    PDF: 695
    HTML: 279
  • Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

    Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4182
    1073
    PDF: 637
    HTML: 36
  • Fluorescence and electron microscopy to visualize the intracellular fate of nanoparticles for drug delivery

    M. Costanzo, F. Carton, A. Marengo, G. Berlier, B. Stella, S. Arpicco, M. Malatesta
    14-04-2016
    https://doi.org/10.4081/ejh.2016.2640
    3084
    PDF: 1306
    HTML: 596
  • Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway

    Y. Zhang, J. Wang, X. Cheng, B. Yi, X. Zhang, Q. Li
    13-04-2015
    https://doi.org/10.4081/ejh.2015.2467
    3434
    PDF: 1520
    HTML: 886
  • Overview of the optical properties of fluorescent nanoparticles for optical imaging

    Federico Boschi, Francesco De Sanctis
    29-08-2017
    https://doi.org/10.4081/ejh.2017.2830
    1701
    PDF: 784
    HTML: 73
  • Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

    J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2256
    3633
    PDF: 894
    HTML: 508
  • Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

    Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4034
    1078
    PDF: 517
    HTML: 8
  • Muc5ac mucin expression during rat skin development

    V. Ferretti, Á. Segal-Eiras, C.G. Barbeito, M.V. Croce
    20-02-2015
    https://doi.org/10.4081/ejh.2015.2462
    2411
    PDF: 804
    HTML: 717
  • P33 | IMPACT OF CYCLIN C EXPRESSION ON THE AGGRESSIVENESS OF A549 NON-SMALL CELL LUNG CANCER CELLS V. Havryliuk | Department of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Poland

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4353
    174
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    214
    PDF: 167
    HTML: 2
  • Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea

    Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong
    01-09-2023
    https://doi.org/10.4081/ejh.2023.3704
    1091
    PDF: 796
    HTML: 21
  • P67 | EMERGING ROLE OF NUCLEAR PHOSPHOLIPASE C BETA 1 AS POTENTIAL BIOMARKER IN LUNG CANCER S. Salucci1, I. Versari1, S. Burattini2, D. Montecchio3, I. Faenza1 | 1Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy; 2Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy; 3Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4392
    232
  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    985
    PDF: 446
    HTML: 16
  • Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

    Chixian Zhang, Kai Bai, Dexu Li
    14-04-2025
    https://doi.org/10.4081/ejh.2025.4186
    1167
    PDF: 420
    HTML: 27
  • Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

    Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren
    12-02-2026
    https://doi.org/10.4081/ejh.2026.4435
    364
    PDF: 283
    HTML: 4
  • Assessment of proliferating cell nuclear antigen and its relationship with proinflammatory cytokines and parameters of disease activity in multiple myeloma patients

    G. Tsirakis, C. A. Pappa, M. Kaparou, V. Katsomitrou, A. Hatzivasili, T. Alegakis, A. Xekalou, E. N. Stathopoulos, M. Alexandrakis
    e21
    01-08-2011
    https://doi.org/10.4081/ejh.2011.e21
    1163
    PDF: 551
    HTML: 1078
  • Dipeptidylpeptidase-­IV, a key enzyme for the degradation of incretins and neuropeptides: activity and expression in the liver of lean and obese rats

    E. Tarantola, V. Bertone, G. Milanesi, E. Capelli, A. Ferrigno, D. Neri, M. Vairetti, S. Barni, I. Freitas
    e41
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e41
    1657
    PDF: 831
    HTML: 1086
  • The tyrosine kinase receptor c-met, its cognate ligand HGF and the tyrosine kinase receptor trasducers STAT3, PI3K and RHO in thyroid nodules associated with Hashimoto's thyroiditis: an immunohistochemical characterization

    R. M. Ruggeri, E. Vitarelli, G. Barresi, F. Trimarchi, S. Benvenga, M. Trovato
    e24
    03-06-2010
    https://doi.org/10.4081/ejh.2010.e24
    1409
    PDF: 650
    HTML: 2589
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3326
    PDF: 846
    HTML: 408
  • Histochemistry in biology and medicine: a message from the citing journals

    Carlo Pellicciari
    23-12-2015
    https://doi.org/10.4081/ejh.2015.2610
    3074
    PDF: 847
    HTML: 893
  • Expression level of quiescin sulfhydryl oxidase 1 (QSOX1) in neuroblastomas

    D.G.B. Araújo, L. Nakao, P. Gozzo, C.D.A. Souza, V. Balderrama, E.S. Gugelmin, A.P. Kuczynski, M. Olandoski, L. de Noronha
    06-03-2014
    https://doi.org/10.4081/ejh.2014.2228
    2942
    PDF: 1235
    HTML: 362
  • Defense and protection mechanisms in lung exposed to asbestiform fiber: the role of macrophage migration inhibitory factor and heme oxygenase-1

    Carla Loreto, Rosario Caltabiano, Adriana Carol Eleonora Graziano, Sergio Castorina, Claudia Lombardo, Vera Filetti, Ermanno Vitale, Giuseppe Rapisarda, Venera Cardile, Caterina Ledda, Venerando Rapisarda
    16-04-2020
    https://doi.org/10.4081/ejh.2020.3073
    1331
    PDF: 796
    HTML: 18
  • Dipeptidylpeptidase-IV activity and expression reveal decreased damage to the intrahepatic biliary tree in fatty livers submitted to subnormothermic machine-perfusion respect to conventional cold storage

    E. Tarantola, V. Bertone, G. Milanesi, C. Gruppi, A. Ferrigno, M. Vairetti, S. Barni, I. Freitas
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2414
    1818
    PDF: 777
    HTML: 568
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1281
    PDF: 205
    HTML: 19
  • Analysis of ERK3 intracellular localization: dynamic distribution during mitosis and apoptosis

    F. Aredia, M. Malatesta, P. Veneroni, M.G. Bottone
    01-12-2015
    https://doi.org/10.4081/ejh.2015.2571
    2330
    PDF: 751
    HTML: 762
  • Molecules involved in the sperm interaction in the human uterine tube: a histochemical and immunohistochemical approach

    David Cajas , Emanuel Guajardo, Sergio Jara-Rosales, Claudio Nuñez, Renato Vargas, Victor Carriel, Antonio Campos, Luis Milla, Pedro Orihuela, Carlos Godoy-Guzman
    13-04-2023
    https://doi.org/10.4081/ejh.2023.3513
    1221
    PDF: 672
    HTML: 39
  • Downregulation of SRPK2 promotes cell cycle arrest though E2F1 in non-small cell lung cancer

    Xin Li, Shaoyu Yang, Minna Zhang, Shuhuan Xie, Zefeng Xie
    11-12-2019
    https://doi.org/10.4081/ejh.2019.3067
    1968
    PDF: 1067
    HTML: 18
  • Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

    Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3412
    2325
    PDF: 1350
    HTML: 31
  • Immunofluorescent characterization of non-myelinating Schwann cells and their interactions with immune cells in mouse mesenteric lymph node

    Zhongli Shi, Wayne K. Greene, Philip K. Nicholls, Dailun Hu, Janina E.E. Tirnitz-Parker, Qionglan Yuan, Changfu Yin, Bin Ma
    07-08-2017
    https://doi.org/10.4081/ejh.2017.2827
    2345
    PDF: 934
    HTML: 159
  • Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

    Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio
    19-10-2023
    https://doi.org/10.4081/ejh.2023.3846
    1634
    PDF: 618
    HTML: 29
  • Immunoreactivity for thymosin beta 4 and thymosin beta 10 in the adult rat oro-gastro-intestinal tract

    S. Nemolato, J. Ekstrom, T. Cabras, C. Gerosa, D. Fanni, E. Di Felice, A. Locci, I. Messana, M. Castagnola, G. Faa
    e17
    07-05-2013
    https://doi.org/10.4081/ejh.2013.e17
    2429
    PDF: 765
    HTML: 526
  • Curculigoside inhibits osteoarthritis via the regulation of NLRP3 pathway

    Xufei Wang, Yinlian Liu, Yongnian Zhou, Yang Zhou, Yueping Li
    13-12-2023
    https://doi.org/10.4081/ejh.2023.3896
    1306
    PDF: 641
    HTML: 15
  • TGF-β1 expression in chromophobe renal cell carcinoma and renal oncocytoma

    A. Demirovic, S. Cesarec, Z. Marusic, D. Tomas, M. Milosevic, T. Hudolin, B. Kruslin
    31-01-2014
    https://doi.org/10.4081/ejh.2014.2265
    2812
    PDF: 676
    HTML: 150
  • Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

    D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev
    05-08-2015
    https://doi.org/10.4081/ejh.2015.2530
    2677
    PDF: 894
    HTML: 1387
  • Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

    Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu
    17-11-2025
    https://doi.org/10.4081/ejh.2025.4426
    666
    PDF: 395
    HTML: 14
  • Porcine intestinal mast cells. Evaluation of different fixatives for histochemical staining techniques considering tissue shrinkage

    J. Rieger, S. Twardziok, H. Huenigen, R. M. Hirschberg, J. Plendl
    e21
    30-07-2013
    https://doi.org/10.4081/ejh.2013.e21
    4178
    PDF: 1113
    HTML: 1299
  • Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

    Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li
    21-01-2025
    https://doi.org/10.4081/ejh.2025.4158
    1691
    PDF: 548
    Supplementary Figure: 68
    HTML: 51
  • MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

    Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3426
    1394
    PDF: 786
    HTML: 25
  • Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

    Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi
    22-05-2024
    https://doi.org/10.4081/ejh.2024.4033
    1090
    PDF: 465
    HTML: 13
  • Immunoreactivities of PPARγ2, leptin and leptin receptor in oviduct of Chinese brown frog during breeding period and pre-hibernation

    Y. Liu, J. Weng, S. Huang, Y. Shen, X. Sheng, Y. Han, M. Xu, Q. Weng
    09-09-2014
    https://doi.org/10.4081/ejh.2014.2422
    1975
    PDF: 744
    HTML: 281
  • The injury of serotonin on intestinal epithelium cell renewal of weaned diarrhoea mice

    Y. Dong, C. Yang, Z. Wang, Z. Qin, J. Cao, Y. Chen
    28-12-2016
    https://doi.org/10.4081/ejh.2016.2689
    2259
    PDF: 855
    HTML: 796
  • Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

    Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan
    11-11-2022
    https://doi.org/10.4081/ejh.2022.3563
    1510
    PDF: 827
    Supplementary: 109
    HTML: 32
  • The penetration of methanol into bovine cardiac and hepatic tissues is faster than ethanol and formalin

    Michelle Steicke, Guang Yang, Tam Nguyen Dinh, Matthew Dunster-Jones, Owen Sargisson, Farah Ahmady, Jonathan Golledge, Yutang Wang
    07-02-2018
    https://doi.org/10.4081/ejh.2018.2880
    1948
    PDF: 788
    Supplementary: 198
    HTML: 48
  • Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

    Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui
    15-02-2022
    https://doi.org/10.4081/ejh.2022.3316
    1795
    PDF: 711
    HTML: 24
  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    149
    PDF: 116
    Raw data: 7
    HTML: 1
  • Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

    R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2547
    1797
    PDF: 1033
    HTML: 352
  • Syndecan expressions in the human amnion and chorionic plate

    T. Lorenzi, A. Turi, C. Crescimanno, M. Morroni, M. Castellucci, G. David, A. L. Tranquilli, D. Marzioni
    e42
    27-10-2010
    https://doi.org/10.4081/ejh.2010.e42
    1753
    PDF: 637
    HTML: 653
  • Investigation of seasonal changes in lipid synthesis and metabolism-related genes in the oviduct of Chinese brown frog (Rana dybowskii)

    Yankun Wang, Yuning Liu, Yawei Wang, Ao Zhang, Wenqian Xie, Haolin Zhang, Qiang Weng, Meiyu Xu
    20-12-2023
    https://doi.org/10.4081/ejh.2023.3890
    1177
    PDF: 621
    HTML: 22
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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