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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • P66 | FROM INNERVATION TO STEROIDOGENIC DEFECT: IMPLICATIONS OF CGRP IN THE PATHOPHYSIOLOGY OF POLYCYSTIC OVARY SYNDROME L. Sallicandro1, R. Gentile2, B. Filová3, S. Polakovičová3, A. Biagini1, F. Ballarino4, D. Del Bianco4, I. Varga5, A. Malvasi6, B. Fioretti2 | 1Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 2Department of Chemistry, Biology and Biotechnologies, University of Perugia, Italy; 3Department of Histology and Embriology, Comenius University, Bratislava, Slovakia; 4Department of Chemistry, Biology and Biotechnologies, University of Perugia, Italy; 5Department of Histology and Embriology, Comenius University, Bratislava, Slovakia; 6Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari Aldo Moro, Bari, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4391
    301
  • Dipeptidylpeptidase-IV activity and expression reveal decreased damage to the intrahepatic biliary tree in fatty livers submitted to subnormothermic machine-perfusion respect to conventional cold storage

    E. Tarantola, V. Bertone, G. Milanesi, C. Gruppi, A. Ferrigno, M. Vairetti, S. Barni, I. Freitas
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2414
    1839
    PDF: 786
    HTML: 571
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2306
    PDF: 670
    HTML: 813
  • NEUROACTIVE STEROIDS PROTECT FROM BORTEZOMIB-INDUCED TOXICITY: EVIDENCE FROM IN VITRO MODELS Fabbro V1, Tonelli E1,2, Scuteri A1,3, D’Aprile C1, Naghshbandieh A1,2, Lim D4, Distasi C4, Giatti S5 and Meregalli C1 | 1School of Medicine and Surgery, Experimental Neurology Unit and Milan Center for Neuroscience, University of Milano- Bicocca, Monza, Italy; 2University of Milano-Bicocca, PhD Program in Neuroscience, Monza, Italy; 3Milan Center for Neuroscience (NeuroMI); 4University of Piemonte Orientale, Department of Pharmaceutical Sciences, Novara, Italy; 5University of Milan, Department of Pharmacological and Biomolecular Sciences “Rodolfo Paoletti”, Milan, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4471
    289
  • miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

    Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3237
    1450
    PDF: 557
    HTML: 25
  • FROM SEEING TO BELIEVING: A 43-YEAR LONG JOURNEY IN IMMUNOSTAINING G. Cattoretti | UNIMIB Pathology, Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4279
    174
  • Quantity of AgNOR in gastric endocrine carcinoid tumours as a potential prognostic tool

    G Giuffrè, F Mormandi, V Barresi, C Bordi, G Tuccari, G Barresi
    45-50
    30-06-2009
    https://doi.org/10.4081/974
    1519
    PDF: 506
  • P69 | MICROPLASTICS AND ATHEROSCLEROSIS: EVIDENCE OF MICROPLASTICS IN CAROTID ATHEROSCLEROTIC PLAQUES R. Sciarrillo1, V. Gallicchio1, A. Lallo1, F. Carrella1, D. Barbarisi2, A. Falzarano1, M. De Falco3, F. Flora2, A. Peluso2, S. Piccolo2, L. Flora2 | 1Department of Science and Technologies, University of Sannio, Italy; 2Vascular Surgery, Hospital of National Importance San Giuseppe Moscati, Italy; 3Department of Biology, University of Naples, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4394
    323
  • Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

    Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3766
    1885
    PDF: 1209
    HTML: 14
  • Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study

    M. Di Rosa, M.A. Szychlinska, D. Tibullo, L. Malaguarnera, G. Musumeci
    16-09-2014
    https://doi.org/10.4081/ejh.2014.2423
    2919
    PDF: 1153
    HTML: 1609
  • EFFECTS OF MATERNAL LOW-PROTEIN AND PHYTOESTROGEN-ENRICHED DIETS ON THE CORRELATION BETWEEN EATING BEHAVIORS AND ANXIETY IN OFFSPRING Ricci E1,2, Ontiveros N1, Bellantoni MT3, Lafaenza S1,4, Gotti S1,2 and Marraudino M1,2 | 1Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano (TO), Italy; 2Department of Neuroscience Rita Levi Montalcini, University of Torino, Torino, Italy; 3Department of Medicine and Surgery, Neuroscience Unit, University of Parma; 4Department of Science and Technological Innovation, DISIT, University of Eastern Piedmont

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4505
    195
  • microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

    Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu
    10-05-2022
    https://doi.org/10.4081/ejh.2022.3333
    1665
    PDF: 881
    HTML: 28
  • Role of Zip1 in the regulation of NPY expression by MLT to promote fracture healing in rats

    Junjun Shang, Bin Ma, Guiling Zhu, Penghong Dong, Chan Wang, Xiaochuan Gu, Ying Zi
    02-12-2020
    https://doi.org/10.4081/ejh.2020.3183
    1827
    PDF: 734
    HTML: 24
  • KAEMPFEROL TARGETS LIPID BALANCE, ENDOCANNABINOID PATHWAYS, AND PPAR-α IN THE RAT CEREBRAL CORTEX AFTER TRANSIENT BILATERAL COMMON CAROTID ARTERY OCCLUSION AND REPERFUSION Serra MP#, Carta G#, Murru E, Boi M, Manca C, Lai Y, Cabboi M, Carta A, Banni S* and Quartu M* | Department of Biomedical Sciences, University of Cagliari, Italy #equal contribution; *co-seniorship

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4475
    264
  • Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

    Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan
    13-05-2024
    https://doi.org/10.4081/ejh.2024.3917
    1825
    PDF: 674
    HTML: 37
  • RANK/RANKL/OPG signaling pathways in necrotic jaw bone from bisphosphonate-treated subjects

    C. Di Nisio, V.L. Zizzari, S. Zara, M. Falconi, G. Teti, G. Tetè, A. Nori, V. Zavaglia, A. Cataldi
    03-02-2015
    https://doi.org/10.4081/ejh.2015.2455
    2747
    PDF: 1126
    HTML: 601
  • Immunolocalization of lactoferrin in surgically resected pigmented skin lesions

    G Tuccari, G Giuffrè, R Scarfì, A Simone, P Todaro, G Barresi
    33-38
    29-06-2009
    https://doi.org/10.4081/924
    908
    PDF: 786
  • P83 | INFLAMMATORY PROFILE IN SKIN, LUNG, AND KIDNEY OF A HOCL-INDUCED MURINE MODEL OF SYSTEMIC SCLEROSIS: AN IMMUNOHISTOCHEMICAL STUDY G. Vermiglio1, J. Freni1, F. Nicita1, A. Centofanti1, D. Labellarte1, E. Rizzuto1, A. Favaloro1, M. Runci Anastasi2, G.P. Anastasi1, G. Cutroneo1 | 1Department of Biomedical, Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy; 2Department of Maxillo-Facial Surgery, University of Rome, La Sapienza, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4409
    258
  • Activation of Hedgehog pathway by circEEF2/miR-625-5p/TRPM2 axis promotes prostate cancer cell proliferation through mitochondrial stress

    ChenHui Zhu, LiJuan Lin, ChangQing Huang, ZhiHui Wu
    11-11-2024
    https://doi.org/10.4081/ejh.2024.4063
    1523
    PDF: 464
    HTML: 11
  • Lipid droplets characterization in adipocyte differentiated 3T3-L1 cells: size and optical density distribution

    V. Rizzatti, F. Boschi, M. Pedrotti, E. Zoico, A. Sbarbati, M. Zamboni
    e24
    06-08-2013
    https://doi.org/10.4081/ejh.2013.e24
    4793
    PDF: 1865
    HTML: 388
  • Distribution of NADPH-diaphorase and AChE activity in the anterior leaflet of rat mitral valve

    K. Lovasova, D. Kluchova, A. Bolekova, F. Dorko, T. Spakovska
    e5
    04-02-2010
    https://doi.org/10.4081/ejh.2010.e5
    1148
    PDF: 464
    HTML: 3089
  • PO54 | FATTY INFILTRATION AND POTENTIAL ADIPOGENIC SHIFT OF SKELETAL MUSCLE CELLS: MULTIPARAMETRIC HISTOLOGICAL ANALYSIS OF MYOSTEATOSIS L. Morello1, G. Stati1, V. Giansante1, S. Lattanzio1, P. Cerritelli1, D. Bruni1, S. Cinti2, R. Di Pietro1,3,4 | 1Department of Medicine and Aging Sciences, “G. d’ Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Experimental and Clinical Medicine, Center of Obesity, Polytechnic University of Marche, Ancona, Italy; 3StemTeCh Group, G. d’ Annunzio Foundation, “G. d’ Annunzio” University of Chieti Pescara, Chieti, Italy; 4Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4379
    260
  • Effects mediated by the α7 nicotinic acetylcholine receptor on cell proliferation and migration in rat adipose-derived stem cells

    Marta Pernarella, Roberta Piovesana, Carlo Matera, Alessandro Faroni, Mario Fiore, Luciana Dini, Adam J. Reid, Clelia Dallanoce, Ada Maria Tata
    30-10-2020
    https://doi.org/10.4081/ejh.2020.3159
    1483
    PDF: 630
    HTML: 12
  • The multifaceted role of podoplanin expression in hepatocellular carcinoma

    Andreea Cioca, Amalia R. Ceausu, Irina Marin, Marius Raica, Anca M. Cimpean
    13-02-2017
    https://doi.org/10.4081/ejh.2017.2707
    2472
    PDF: 833
    HTML: 317
  • UNRAVELING GLIAL REMODELING IN SPACE AND TIME DURING GLIOBLASTOMA EVOLUTION Riccio L1, De Luca C1, Rega C1, Papa M1 and Virtuoso A1 | 1Laboratory of Neuronal Networks Morphology and System Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4477
    256
  • Molecules involved in the sperm interaction in the human uterine tube: a histochemical and immunohistochemical approach

    David Cajas , Emanuel Guajardo, Sergio Jara-Rosales, Claudio Nuñez, Renato Vargas, Victor Carriel, Antonio Campos, Luis Milla, Pedro Orihuela, Carlos Godoy-Guzman
    13-04-2023
    https://doi.org/10.4081/ejh.2023.3513
    1278
    PDF: 691
    HTML: 40
  • LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma

    Nuobei Zhang, Hao Shen, Shenan Huang, Fenfen Wang, Huifang Liu, Fen Xie, Lei Jiang, Xin Chen
    16-11-2021
    https://doi.org/10.4081/ejh.2021.3300
    1232
    PDF: 634
    HTML: 48
  • Inhibition of APLN suppresses cell proliferation and migration and promotes cell apoptosis in esophageal cancer cells in vitro, through activating PI3K/mTOR signaling pathway

    Yuhan Wang, Gang Wang, Xiaojun Liu, Dong Yun, Qing Cui, Xiaoting Wu, Wenfeng Lu, Xiwen Yang, Ming Zhang
    03-08-2022
    https://doi.org/10.4081/ejh.2022.3336
    1435
    PDF: 721
    HTML: 41
  • Oxygen tension-independent protection against hypoxic cell killing in rat liver by low sodium

    Andrea Ferrigno, Laura G. Di Pasqua, Clarissa Berardo, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti
    30-05-2017
    https://doi.org/10.4081/ejh.2017.2798
    1910
    PDF: 688
    HTML: 75
  • Elastofibroma dorsi: a histochemical and immunohistochemical study

    A. Di Vito, E. Scali, G. Ferraro, C. Mignogna, I. Presta, C. Camastra, C. Palmieri, G. Donato, T. Barni
    19-02-2015
    https://doi.org/10.4081/ejh.2015.2459
    2676
    PDF: 872
    HTML: 1097
  • Effect of retinal ablation on the expression of calbindin D28k and GABA in the chick optic tectum

    G Díaz de Barboza, C Beltramino, L Britto, J De Olmos, S De Olmos
    365-372
    26-06-2009
    https://doi.org/10.4081/848
    794
    PDF: 638
  • Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study

    Giada Remoli, Chiara Rita Inguscio, Federico Boschi, Gabriele Tabaracci, Manuela Malatesta, Barbara Cisterna
    26-01-2026
    https://doi.org/10.4081/ejh.2026.4440
    399
    PDF: 199
    HTML: 8
  • Bradykinin and noradrenaline preconditioning influences level of antioxidant enzymes SOD, CuZn-SOD, Mn-SOD and catalase in the white matter of spinal cord in rabbits after ischemia/reperfusion

    Marianna Danková, Iveta Domoráková, Zuzana Fagová, Milan Stebnický, Alexandra Kunová, Eva Mechírová
    18-10-2019
    https://doi.org/10.4081/ejh.2019.3045
    1612
    PDF: 713
    HTML: 10
  • Lorenzo Gotte (1926-1991): a pioneer of elastin

    M. Onisto, S. Garbisa, M. Spina
    30-09-2016
    https://doi.org/10.4081/ejh.2016.2713
    1380
    PDF: 668
    HTML: 204
  • Transient receptor potential canonical 3/5 attenuate endothelial damage-induced neointima formation without affecting endothelial cell proliferation

    Wenjun Zeng, Bei Liu, Lixia Yang, Ruiwei Guo
    19-11-2025
    https://doi.org/10.4081/ejh.2025.4311
    368
    PDF: 185
    HTML: 16
  • Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

    Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan
    11-11-2022
    https://doi.org/10.4081/ejh.2022.3563
    1549
    PDF: 838
    Supplementary: 113
    HTML: 33
  • In vitro reparative dentin: a biochemical and morphological study

    G. Teti, V. Salvatore, A. Ruggeri, L. Manzoli, M. Gesi, G. Orsini, M. Falconi
    e23
    06-08-2013
    https://doi.org/10.4081/ejh.2013.e23
    3227
    PDF: 820
    HTML: 938
  • P56 | HISTOLOGICAL PROFILE OF INACTIVE UNILATERAL CONDYLAR HYPERPLASIA: EVIDENCE OF BORDERLINE TISSUE ACTIVITY F. Nicita1, G. Vermiglio1, J. Freni1, A. Centofanti1, D. Labellarte1, R. Briganti1, G.P. Anastasi1, G. Cutroneo1, A. Favaloro1, M. Runci Anastasi2 | 1Department of Biomedical, Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy; 2Department of Maxillo-Facial Surgery, University of Rome, La Sapienza, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4381
    249
  • Hepatocyte growth factor intervention to reduce myocardial injury and improve cardiac function on diabetic myocardial infarction rats

    Zaiyong Zhang, Cheng Long, Yufeng Guan, Mingcai Song
    30-07-2020
    https://doi.org/10.4081/ejh.2020.3142
    1346
    PDF: 725
    HTML: 14
  • Reelin expression in human liver of patients with chronic hepatitis C infection

    Simone Carotti, Giuseppe Perrone, Michelina Amato, Umberto Vespasiani Gentilucci, Daniela Righi, Maria Francesconi, Claudio Pellegrini, Francesca Zalfa, Maria Zingariello, Antonio Picardi, Andrea Onetti Muda, Sergio Morini
    17-03-2017
    https://doi.org/10.4081/ejh.2017.2745
    3160
    PDF: 976
    HTML: 366
  • HIGH RESOLUTION MAGNETIC RESONANCE IMAGING TO ASSESS AXONAL DAMAGE IN NEUROPATHY MODELS Bontempi P1, Mastropietro A2, Rizzo G2, Taccogna M2, Napolitano A3, Gerevini S4, Kraus MF5,6, Di Girolamo S5,7, Cavaletti G5,7, Tamburin S8 and Alberti P5,7 | 1Department of Engineering for Innovation Medicine, University of Verona, Verona, Italy; 2Institute for Biomedical Technologies, National Research Council (ITB-CNR), Segrate, Italy; 3Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy; 4Department of Neuroradiology, ASST Papa Giovanni XXIII, Bergamo, Italy; 5Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy 6S.C. Neuroscienze, Istituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle D’Aosta, Torino, Italy; 7NeuroMI (Milan Center for Neuroscience), Milan, Italy; 8Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4480
    248
  • miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

    Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4161
    1389
    PDF: 441
    HTML: 24
  • miR-29a-3p enhances the radiosensitivity of oral squamous cell carcinoma cells by inhibiting ADAM12

    Cuihong Jiang, Feng Liu , Shuai Xiao, Lili He, Wenqiong Wu, Qi Zhao
    27-09-2021
    https://doi.org/10.4081/ejh.2021.3295
    1305
    PDF: 871
    HTML: 25
  • In memoriam of Prof. Giuseppe Gerzeli

    Sergio Barni
    15-02-2018
    https://doi.org/10.4081/ejh.2018.2899
    844
    PDF: 391
  • Correlation between PARP-1 immunoreactivity and cytomorphological features of parthanatos, a specific cellular death in breast cancer cells

    P. Donizy, A. Halon, P. Surowiak, G. Pietrzyk, C. Kozyra, R. Matkowski
    e35
    20-11-2013
    https://doi.org/10.4081/ejh.2013.e35
    3805
    PDF: 799
    HTML: 337
  • P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini1, S. Leone1, R. Mancinelli1, R. Vaccaro1, M. Catalano2, G. D’Alessandro2, A. Rinaldi2, A. Reccagni2, G. Vivacqua3, A. Franchitto4, P. Onori1, C. Limatola2, E. Gaudio1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; 2Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; 3Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; 4Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4333
    154
  • Gemst: a taylor-made combination that reverts neuroanatomical changes in stroke

    Arturo Mangas, Javier Yajeya, Noelia González, Isabel Ruiz, Marianny Pernía, Michel Geffard, Rafael Coveñas
    25-05-2017
    https://doi.org/10.4081/ejh.2017.2790
    1772
    PDF: 676
    HTML: 195
  • AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in autophagy-induced astrocytoma cells

    L. Fassina, G. Magenes, A. Inzaghi, S. Palumbo, G. Allavena, C. Miracco, L. Pirtoli, M. Biggiogera, S. Comincini
    e44
    11-10-2012
    https://doi.org/10.4081/ejh.2012.e44
    2012
    PDF: 972
    Supplementary Figures: 305
    Supplementary Table: 223
    HTML: 500
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European Journal of Histochemistry

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