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A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer

Daniëlle Krijgsman, Ronald L.P. van Vlierberghe, Vaios Evangelou, Alexander L. Vahrmeijer, Cornelis J.H. van de Velde, Cornelis F.M. Sier, Peter J.K. Kuppen

20-05-2019

https://doi.org/10.4081/ejh.2019.3028

1693

PDF: 832

Supplementary: 233

HTML: 23
Sporadic Creutzfeldt-Jakob disease: Real-Time Quaking Induced Conversion (RT-QuIC) assay represents a major diagnostic advance

Federico Angelo Cazzaniga, Edoardo Bistaffa, Chiara Maria Giulia De Luca, Giuseppe Bufano, Antonio Indaco, Giorgio Giaccone, Fabio Moda

15-10-2021

https://doi.org/10.4081/ejh.2021.3298

3514

PDF: 1235

HTML: 40
Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity

Bita Moudi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Seyed-Moayed Alavian, Kamran B. Lankarani, Parisa Farrokh, Jens Randel Nyengaard

29-01-2018

https://doi.org/10.4081/ejh.2018.2859

2399

PDF: 1111

HTML: 84
alpha2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade

Michael W.L. Quirino, Amanda P.B. Albuquerque, Maria F.D. de Souza, Antônio F. da Silva Filho, Mário R. Martins, Maira G. da Rocha Pitta, Michelly C. Pereira, Moacyr J.B. de Melo Rêgo

29-09-2022

https://doi.org/10.4081/ejh.2022.3330

1597

PDF: 877

Supplementary: 143

HTML: 36
Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

A.C. Croce, G. Bottiroli

12-12-2014

https://doi.org/10.4081/ejh.2014.2461

14961

PDF: 6211

HTML: 8011
High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari

16-12-2024

https://doi.org/10.4081/ejh.2024.4145

1496

PDF: 622

HTML: 12
Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma

Zhiyang Wang, Jing Li, Ziwei Liu, Ling Yue

20-03-2023

https://doi.org/10.4081/ejh.2023.3622

1619

PDF: 872

HTML: 41
Next-generation nutritional biomarkers to guide better health care

CarloAlberto Redi

19-04-2016

https://doi.org/10.4081/ejh.2016.2666

1385

PDF: 746

HTML: 112
New light in flavin autofluorescence

A.C. Croce, G. Bottiroli

10-11-2015

https://doi.org/10.4081/ejh.2015.2576

2399

PDF: 1023

HTML: 359
Expression of 8-OHdG in Zosterisessor ophiocephalus from the Venetian lagoon, Italy

E. Negrato, M. Vascellari, F. Capolongo, G. Binato, L. Da Dalt, M. Boscolo Papo, G. Gioacchini, O. Carnevali, D. Bertotto, G. Radaelli, F. Pascoli

e8

19-02-2013

https://doi.org/10.4081/ejh.2013.e8

3557

PDF: 865

HTML: 683
Lipids: Evergreen autofluorescent biomarkers for the liver functional profiling

Anna Cleta Croce, Giovanni Bottiroli

01-06-2017

https://doi.org/10.4081/ejh.2017.2808

1849

PDF: 903

HTML: 139
Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng

03-09-2021

https://doi.org/10.4081/ejh.2021.3264

2079

PDF: 777

Supplementary: 159

HTML: 33
Exploring the efficacy of AMACR, ERG, and AR immunostains in prostatic adenocarcinoma and their association with novel grade groups

Mohamed O. Andarawi, Hassan Otifi, Hesham Hassan, Adil A. Yousif , Saadalnour A. Mustafa, Shawgi A. Elsiddig , Asad Ma Babker, Elryah I. Ali , Omer Osman Elhag

11-02-2025

https://doi.org/10.4081/ejh.2025.4172

1442

PDF: 433

HTML: 23
Lectins as versatile tools to explore cellular glycosylation

Susan Brooks

29-01-2024

https://doi.org/10.4081/ejh.2024.3959

3048

PDF: 1281

HTML: 54
Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng

02-10-2023

https://doi.org/10.4081/ejh.2023.3839

1577

PDF: 868

HTML: 43
Effects of different rearing temperatures on muscle development and stress response in the early larval stages of Acipenser baerii

Lucia Aidos, Luisa M. Pinheiro Valente, Vera Sousa, Marco Lanfranchi, Cinzia Domeneghini, Alessia Di Giancamillo

28-11-2017

https://doi.org/10.4081/ejh.2017.2850

2272

PDF: 661

HTML: 177
Pleural mesothelioma from fluoro-edenite exposure: PACAP and PAC1 receptor. A preliminary report

Claudia Lombardo, Grazia Maugeri, Agata Grazia D'Amico, Giuseppe Broggi, Rosario Caltabiano, Veronica Filetti, Serena Matera, Velia D'Agata, Carla Loreto

02-05-2024

https://doi.org/10.4081/ejh.2024.3994

1779

PDF: 608

HTML: 36
miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen

07-04-2025

https://doi.org/10.4081/ejh.2025.4161

1629

PDF: 522

HTML: 34
Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma

Lulu Le, Ji Luo, Haifang Wu, Ling Chen, Xiaoli Tang, Fen Fu

30-03-2021

https://doi.org/10.4081/ejh.2021.3226

2168

PDF: 926

Supplementary: 207

HTML: 34
Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1

S. Iachettini, R. Valaperta, A. Marchesi, A. Perfetti, G. Cuomo, B. Fossati, L. Vaienti, E. Costa, G. Meola, R. Cardani

26-10-2015

https://doi.org/10.4081/ejh.2015.2562

2094

PDF: 984

HTML: 399
The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration

Flavia Carton

23-02-2023

https://doi.org/10.4081/ejh.2023.3679

2065

PDF: 1051

HTML: 50
MiR-550a-3p restores damaged vascular smooth muscle cells by inhibiting thrombomodulin in an in vitro atherosclerosis model

Shiyuan Chen, Longfei Zhang, Benchi Feng, Wei Wang, Delang Liu, Xinyu Zhao, Chaowen Yu, Xiaogao Wang, Yong Gao

19-07-2022

https://doi.org/10.4081/ejh.2022.3429

1313

PDF: 728

Supplementary: 150

HTML: 42
Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

25-08-2017

https://doi.org/10.4081/ejh.2017.2826

3183

PDF: 1354

HTML: 151
Mammaglobin, GATA-binding protein 3 (GATA3), and epithelial growth factor receptor (EGFR) expression in different breast cancer subtypes and their clinical significance

Xin Kong, Qi Wang, Jie Li, Ming Li, Fusheng Deng, Chuanying Li

07-04-2022

https://doi.org/10.4081/ejh.2022.3315

1816

PDF: 859

Supplementary: 172

HTML: 19
Aberrant expression of CCDC69 in breast cancer and its clinicopathologic significance

Jinjiao Li, Panshi Zhang, Yun Xia

22-02-2021

https://doi.org/10.4081/ejh.2021.3207

1653

PDF: 902

HTML: 40
Effects of lead pollution on Ammonia parkinsoniana (foraminifera): ultrastructural and microanalytical approaches

F. Frontalini, D. Curzi, F.M. Giordano, J.M. Bernhard, E. Falcieri, R. Coccioni

30-01-2015

https://doi.org/10.4081/ejh.2015.2460

2653

PDF: 926

HTML: 1130
miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi

23-09-2025

https://doi.org/10.4081/ejh.2025.4238

513

PDF: 465

HTML: 16
The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li

25-11-2021

https://doi.org/10.4081/ejh.2021.3323

2009

PDF: 764

HTML: 39
Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan

13-05-2024

https://doi.org/10.4081/ejh.2024.3917

2145

PDF: 906

HTML: 54
Differential expression patterns of N-acetylglucosaminyl transferases and polylactosamines in uterine lesions

A.T.R. Clark, V.M.L. Guimaraes da Costa, L. Bandeira Costa, C.L. Bezerra Cavalcanti, M.J.B. de Melo Rego, E.I.C. Beltrao

26-05-2014

https://doi.org/10.4081/ejh.2014.2334

2530

PDF: 1794

HTML: 409
Detection of cancer clones in human gastric adenoma by increased DNA-instability and other biomarkers

A Sun, S Noriki, Y Imamura, M Fukuda

111-122

26-06-2009

https://doi.org/10.4081/815

803

PDF: 731
Forever particles: histochemistry in the plasticene age

Beatrice Camia, Andrea Casasco, Manuela Monti

01-08-2025

https://doi.org/10.4081/ejh.2025.4226

1519

PDF: 649

HTML: 62
GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location

Mário S. de Souza Albuquerque, Antônio F. da Silva-filho, Marina Ferraz Cordeiro, Maria de Fátima Deodato de Souza, Michael W.L. Quirino, Luiza R. Amorim Lima, Maira G. da Rocha Pitta, Mario R. Martins, Moacyr J.B. de Melo Rêgo

14-06-2018

https://doi.org/10.4081/ejh.2018.2931

3592

PDF: 631

Supplementary: 245

HTML: 34
Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang

17-09-2024

https://doi.org/10.4081/ejh.2024.4034

1315

PDF: 693

HTML: 17
Immunopositivity for Siglec-15 in gastric cancer and its association with clinical and pathological parameters

Michael Williams Leal Quirino, Michelly Cristiny Pereira, Maria de Fátima Deodato de Souza, Ivan da Rocha Pitta, Antônio Felix da Silva Filho, Mario S. de Souza Albuquerque, Amanda Pinheiro de Barros Albuquerque, Mário Rino Martins, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo

04-03-2021

https://doi.org/10.4081/ejh.2021.3174

8398

PDF: 1310

Supplementary: 244

HTML: 21
Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu

17-11-2025

https://doi.org/10.4081/ejh.2025.4426

1089

PDF: 543

HTML: 22
CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure

S. Huang, S. Guo, F. Guo, Q. Yang, X. Xiao, M. Murata, S. Ohnishi, S. Kawanishi, N. Ma

e1

14-01-2013

https://doi.org/10.4081/ejh.2013.e1

2145

PDF: 921

HTML: 895
The role of galanin in the progression and prognosis of colorectal cancer: the unfinished story

Zbigniew Kmiec, Jacek Kieżun, Bartlomiej E. Krazinski, Przemyslaw Kwiatkowski, Janusz Godlewski

06-03-2024

https://doi.org/10.4081/ejh.2024.3990

1684

PDF: 531

HTML: 19
The role of miR-143-3p/FNDC1 axis on the progression of non-small cell lung cancer

Zhanshu Ma, Qi Gao, Wenjing Xin, Lei Wang, Yan Chen, Chang Su, Songyan Gao, Ruiling Sun

03-05-2023

https://doi.org/10.4081/ejh.2023.3577

2139

PDF: 644

HTML: 40
Evaluation of expression of Toll-Like Receptors 7 and 9, proliferation, and cytoskeletal biomarkers in plaque and guttate psoriasis: A pilot morphological study

Francesca Prignano, Giulia Lombardo, Serena Indino, Federica Ricceri, Laura Cornaghi, Elena B. Donetti

05-03-2021

https://doi.org/10.4081/ejh.2021.3218

1779

PDF: 725

HTML: 21
FLOW CYTOMETRY IN THE DEVELOPMENT AND CHARACTERIZATION OF PRECLINICAL TUMOR MODELS BASED ON THE ANALYSIS OF EXTRACELLULAR VESICLES AS CANDIDATE LIQUID BIOMARKERS I. D’Agnano | Institute of Biomedical Technologies, CNR, Segrate, Milan, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4303

201
Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

Jiapei Lv, Wang Yanting, Shan Wei

08-11-2023

https://doi.org/10.4081/ejh.2023.3867

2172

PDF: 1085

HTML: 62
Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

16-12-2016

https://doi.org/10.4081/ejh.2016.2711

2696

PDF: 1178

HTML: 315
High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos

17-02-2022

https://doi.org/10.4081/ejh.2022.3360

2711

PDF: 1071

HTML: 47
miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

Nan Xu, Ang-Di Li, Li-Li Ji, Yao Ye, Zhen-Yu Wang, Lei Tong

03-05-2019

https://doi.org/10.4081/ejh.2019.3008

3005

PDF: 1247

HTML: 23
Downregulation of GMPS inhibited the proliferation of hepatocellular cancer cells via the regulation of STAT3/c-Myc pathway

Zhibin Guo, Juan Yu, Jing Sun, Sheng Yang, Jiang Pu

15-06-2026

https://doi.org/10.4081/ejh.2026.4541

166

PDF: 173

Supplementary: 31

HTML: 7
Expressions of ZNF436, β-catenin, EGFR, and CMTM5 in breast cancer and their clinical significances

Zhi Chen, Na Cui, Ji-sen Zhao, Jian-fei Wu, Fang Ma, Cong Li, Xian-yi Liu

20-01-2021

https://doi.org/10.4081/ejh.2021.3173

2421

PDF: 867

Supplementary: 208

HTML: 22
Long non-coding RNA WAC antisense RNA 1 mediates hepatitis B virus replication in vitro by reinforcing miR-192-5p/ATG7-induced autophagy

Minkai Cao, Deping Yuan, Hongxiu Jiang, Guanlun Zhou, Chao Chen, Guorong Han

02-09-2022

https://doi.org/10.4081/ejh.2022.3438

1604

PDF: 980

HTML: 52
Identifying pathological biomarkers: histochemistry still ranks high in the omics era

C. Pellicciari, M. Malatesta

e42

07-12-2011

https://doi.org/10.4081/ejh.2011.e42

2418

PDF: 883
miRNA-877-5p inhibits malignant progression of prostate cancer by directly targeting SSFA2

Wanchun Wang, Jun Yi, Degang Dong, Wenli Mao, Xuanyu Wang, Zhangren Yan

20-09-2021

https://doi.org/10.4081/ejh.2021.3243

1470

PDF: 756

HTML: 43
miR-19a targeting CLCA4 to regulate the proliferation, migration, and invasion of colorectal cancer cells

Huiwen Li, Bo Huang

10-03-2022

https://doi.org/10.4081/ejh.2022.3381

2206

PDF: 782

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MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells

J. Zhang, J. Luo, J. Ni, L. Tang, H.P. Zhang, L. Zhang, J.F. Xu, D. Zheng

18-02-2014

https://doi.org/10.4081/ejh.2014.2262

3555

PDF: 1076

HTML: 334
P27 | HISTOCHEMICAL APPROACHES FOR EVALUATING THE REPRODUCTIVE HEALTH OF MUSSEL MYTILUS GALLOPROVINCIALIS EXPOSED TO ACUTE THERMAL STRESS M. Galati, M. A. Oueldi, M. Romeo, T. Cappello, M. Maisan | Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4347

209
Expression patterns of Î±2,3-Sialyltransferase I and Î±2,6-Sialyltransferase I in human cutaneous epithelial lesions

S.A. Ferreira, J.L.A. Vasconcelos, R.C.W.C. Silva, C.L.B. Cavalcanti, C.L. Bezerra, M.J.B.M. RÃªgo, E.I.C. BeltrÃ£o

e7

14-02-2013

https://doi.org/10.4081/ejh.2013.e7

1606

PDF: 810

HTML: 239
Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi

23-06-2022

https://doi.org/10.4081/ejh.2022.3377

1869

PDF: 1003

HTML: 29
LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma

Nuobei Zhang, Hao Shen, Shenan Huang, Fenfen Wang, Huifang Liu, Fen Xie, Lei Jiang, Xin Chen

16-11-2021

https://doi.org/10.4081/ejh.2021.3300

1374

PDF: 727

HTML: 56
Histochemistry as a versatile research toolkit in biological research, not only an applied discipline in pathology

Carlo Pellicciari

21-12-2018

https://doi.org/10.4081/ejh.2018.3006

2212

PDF: 835

HTML: 31
P19 | IDENTIFICATION OF MIR-129-5P AS A COMMON REGULATOR OF E3 UBIQUITIN LIGASES WITH A POTENTIAL ROLE IN GLIOBLASTOMA PROGRESSION N. Martella¹, A.B. Díaz Méndez², G. Regazzo², G.F. Bufalieri³, A. Frati⁴, A. Arcella⁴, L. Di Marcotullio³, M.G. Rizzo², S. Di Bartolomeo¹ | ¹Dept. of Biosciences and Territory, University of Molise, Italy; ²Dept. of Research, Advanced Diagnostics and Technological Innovation, Translational Oncology Research Unit, IRCCS -Regina Elena National Cancer Institute, Rome, Italy; ³Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy; ⁴IRCCS Neuromed, Pozzilli (IS), Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4715

82

PDF: 43
Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du

05-05-2025

https://doi.org/10.4081/ejh.2025.4178

1085

PDF: 451

Supplementary: 65

HTML: 56
KiSS1 inhibits growth and invasion of osteosarcoma cells through inhibition of the MAPK pathway

Y. Zhang, Y.J. Tang, Z.H. Li, F. Pan, K. Huang, G.H. Xu

e30

29-10-2013

https://doi.org/10.4081/ejh.2013.e30

2893

PDF: 762

HTML: 318
Expression of E-cadherin, Ki-67, and p53 in urinary bladder cancer in relation to progression, survival, and recurrence

Stanislav Ziaran, Stefan Harsanyi, Katarina Bevizova, Zuzana Varchulova Novakova, Branislav Trebaticky, Peter Bujdak, Stefan Galbavy, Lubos Danisovic

26-03-2020

https://doi.org/10.4081/ejh.2020.3098

1640

PDF: 879

HTML: 32
P59 | IMMUNOHISTOCHEMISTRY ANALYSIS TO DETECT A MOLECULAR SIGNATURE IN INTERVERTEBRAL DISC DEGENERATION L. Penolazzi¹, R. Nadalini¹, C. Sief¹, E. Lambertini², C. Angelini³, R. Piva¹ | ¹Department of Neurosciences and rehabilitation, University of Ferrara, Italy; ²Laboratorio Centralizzato di ricerca preclinica, University of Ferrara, Italy; ³Department of Translational Medicine, University of Ferrara, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4384

305
Cancer stem cell markers ALDH1 and CD44+/CD24- phenotype and their prognosis impact in invasive ductal carcinoma

Iris Rabinovich, Ana Paula Martins Sebastião, Rubens Silveira Lima, Cícero de Andrade Urban, Eduardo Schunemann Junior, Karina Furlan Anselmi, Selene Elifio-Esposito, Lucia de Noronha, Andréa Novais Moreno-Amaral

03-09-2018

https://doi.org/10.4081/ejh.2018.2943

3063

PDF: 1150

HTML: 43
SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang

18-05-2026

https://doi.org/10.4081/ejh.2026.4544

256

PDF: 231

Supplementary: 41

HTML: 12
Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera

20-04-2022

https://doi.org/10.4081/ejh.2022.3409

1888

PDF: 1005

HTML: 33
MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices

Elena Casiraghi, Mara Cossa, Veronica Huber, Licia Rivoltini, Matteo Tozzi, Antonello Villa, Barbara Vergani

02-11-2017

https://doi.org/10.4081/ejh.2017.2838

2551

PDF: 1248

MIAQuant user Manual: 288

MIAQuant source code: 367

HTML: 80
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li

22-09-2025

https://doi.org/10.4081/ejh.2025.4239

588

PDF: 442

Supplementary: 72

HTML: 24
MMP-7 and MMP-9 are overexpressed in the synovial tissue from severe temporomandibular joint dysfunction

Carla Loreto, Vera Filetti, Luis Eduardo Almeida, Giusy Rita Maria La Rosa, Rosalia Leonardi , Cristina Grippaudo , Antonino Lo Giudice

16-04-2020

https://doi.org/10.4081/ejh.2020.3113

1991

PDF: 864

HTML: 30
Mena, a new available marker in tumors of salivary glands?

S. Gurzu, M. Krause, I. Ember, L. Azamfirei, G. Gobel, K. Feher, I. Jung

e8

07-02-2012

https://doi.org/10.4081/ejh.2012.e8

1455

PDF: 730

HTML: 4182
P67 | EMERGING ROLE OF NUCLEAR PHOSPHOLIPASE C BETA 1 AS POTENTIAL BIOMARKER IN LUNG CANCER S. Salucci¹, I. Versari¹, S. Burattini², D. Montecchio³, I. Faenza¹ | ¹Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy; ²Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy; ³Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4392

312
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang

20-04-2026

https://doi.org/10.4081/ejh.2026.4548

677

PDF: 403

Raw data: 53

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Premature senescence in primary muscle cultures of myotonic dystrophy type 2 is not associated with p16 induction

L.V. Renna, R. Cardani, A. Botta, G. Rossi, B. Fossati, E. Costa, G. Meola

22-10-2014

https://doi.org/10.4081/ejh.2014.2444

2495

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Effect of CDX2 on proliferation, invasion, migration, and apoptosis of duodenal cancer cells

Jun Pan, Yi Zhao, Yu Zhang, Yuhe Zhou, Fengxuan Zhang, Yitian Chen, Xiaoyuan Chu

24-04-2025

https://doi.org/10.4081/ejh.2025.4203

853

PDF: 385

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Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation

Hongkai Xiao, Jinghu Liu, Qinhong Cai, Siyu Liang, Zhitao Hu, Xiaochao Chen

13-10-2025

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893

PDF: 460

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The substance P and neurokinin-1 receptor system in human thyroid cancer: an immunohistochemical study

Inmaculada Isorna, Francisco Esteban, Juan Solanellas, Rafael Coveñas, Miguel Muñoz

28-04-2020

https://doi.org/10.4081/ejh.2020.3117

1438

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P69 | MICROPLASTICS AND ATHEROSCLEROSIS: EVIDENCE OF MICROPLASTICS IN CAROTID ATHEROSCLEROTIC PLAQUES R. Sciarrillo¹, V. Gallicchio¹, A. Lallo¹, F. Carrella¹, D. Barbarisi², A. Falzarano¹, M. De Falco³, F. Flora², A. Peluso², S. Piccolo², L. Flora² | ¹Department of Science and Technologies, University of Sannio, Italy; ²Vascular Surgery, Hospital of National Importance San Giuseppe Moscati, Italy; ³Department of Biology, University of Naples, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4394

432
Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li

17-05-2023

https://doi.org/10.4081/ejh.2023.3612

1649

PDF: 972

Supplementary: 111

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Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye

30-09-2021

https://doi.org/10.4081/ejh.2021.3224

3848

PDF: 1956

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Low ozone concentrations promote adipogenesis in human adipose-derived adult stem cells

Manuela Costanzo, Federico Boschi, Flavia Carton, Giamaica Conti, Viviana Covi, Gabriele Tabaracci, Andrea Sbarbati, Manuela Malatesta

03-09-2018

https://doi.org/10.4081/ejh.2018.2969

2724

PDF: 864

Supplementary: 381

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Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu

11-05-2026

https://doi.org/10.4081/ejh.2026.4557

452

PDF: 628

Supplementary: 50

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Effects of artificial light with different spectral compositions on refractive development and matrix metalloproteinase 2 and tissue inhibitor of metalloproteinases 2 expression in the sclerae of juvenile guinea pigs

Jianbao Yuan, Linfang Li, Yi Fan, Xinyu Xu, Xiaoqiong Huang, Jiayu Shi, Chuanwei Zhang, Lixin Shi, Yuliang Wang

27-06-2024

https://doi.org/10.4081/ejh.2024.3982

1843

PDF: 590

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Chemotherapy-induced nephrotoxicity was improved by crocin in mouse model

Qichao Yin, Hua Xiong

03-10-2022

https://doi.org/10.4081/ejh.2022.3541

1140

PDF: 717

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Prognostic significance of CD133 and ABCB5 expression in papillary thyroid carcinoma

Maria Augusta Karas Zella, Ana Paula Martins Sebastião, Luiz Martins Collaço, Daniel Cury Ogata, Guilherme Cecchetti, Ivan José Paredes Bartolomei, Ana Maria Waaga-Gasser, Carmen Australia Paredes Marcondes Ribas

12-11-2020

https://doi.org/10.4081/ejh.2020.3143

1511

PDF: 621

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Radioprotective potential of histamine on rat small intestine and uterus

E. Carabajal, N. Massari, M. Croci, D. J. Martinel Lamas, J. P. Prestifilippo, R. M. Bergoc, E. S. Rivera, V. A. Medina

e48

18-12-2012

https://doi.org/10.4081/ejh.2012.e48

1444

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ASTROCYTE DYSFUNCTION IN AUTOSOMAL DOMINANT LEUKODYSTROPHY (ADLD): INSIGHTS FROM 2D AND 3D IN VITRO SYSTEMS AND EX VIVO CEREBROSPINAL FLUID METABOLOMICS F.D. Koufi¹, V. Righi², A. Mucci³, I. Rusciano¹, S. Mongiorgi¹, M. Shin⁴, Y. Kosodo⁴, I. Cani⁵, P. Cortelli⁶, E. Giorgio⁷, G. Ramazzotti¹, L. Manzoli¹, S. Ratti¹ | ¹ Cellular Signaling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; ²Department of Life Quality Studies, University of Bologna, Campus of Rimini, Rimini, Italy; ³Department of Geological and Chemical Sciences, University of Modena and Reggio Emilia, Modena, Italy; ⁴Korea Brain Research Institute (KBRI), Daegu, Republic of Korea; ⁵Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; ⁶IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; ⁷Department of Molecular Medicine, University of Pavia, Pavia, Italy; Medical Genetics Unit, IRCCS Mondino Foundation, Pavia, Italy.

21-08-2025

https://doi.org/10.4081/ejh.2025.4312

366
Curculigoside inhibits osteoarthritis via the regulation of NLRP3 pathway

Xufei Wang, Yinlian Liu, Yongnian Zhou, Yang Zhou, Yueping Li

13-12-2023

https://doi.org/10.4081/ejh.2023.3896

1534

PDF: 727

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Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li

21-01-2025

https://doi.org/10.4081/ejh.2025.4158

1940

PDF: 643

Supplementary Figure: 112

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Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li

25-10-2022

https://doi.org/10.4081/ejh.2022.3529

1857

PDF: 898

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An ex vivo study on immunohistochemical localization of MMP-7 and MMP-9 in temporomandibular joint discs with internal derangement

C. Loreto, R. Leonardi, G. Musumeci, G. Pannone, S. Castorina

e12

15-04-2013

https://doi.org/10.4081/ejh.2013.e12

2946

PDF: 907

HTML: 446
Folic acid promotes autophagy to relieve metabolism-associated fatty liver disease by regulating NRF2

Yu Wen, Juan Luo, Chunjing Shi, Jie Wu

03-11-2025

https://doi.org/10.4081/ejh.2025.4309

1048

PDF: 624

HTML: 39
Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi

22-05-2024

https://doi.org/10.4081/ejh.2024.4033

1330

PDF: 583

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The psoriatic shift induced by interleukin 17 is promptly reverted by a specific anti-IL-17A agent in a three-dimensional organotypic model of normal human skin culture

Elena Donetti, Giulia Lombardo, Serena Indino, Laura Cornaghi, Francesca Arnaboldi, Leonardo Pescitelli, Franz Baruffaldi Preis, Francesca Prignano

16-04-2020

https://doi.org/10.4081/ejh.2020.3115

1320

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Expression level of quiescin sulfhydryl oxidase 1 (QSOX1) in neuroblastomas

D.G.B. AraÃºjo, L. Nakao, P. Gozzo, C.D.A. Souza, V. Balderrama, E.S. Gugelmin, A.P. Kuczynski, M. Olandoski, L. de Noronha

06-03-2014

https://doi.org/10.4081/ejh.2014.2228

3119

PDF: 1310

HTML: 366
Elevated caspase 3 expression correlates with severe inflammation in Crohn’s disease

Nafie Sejdiu, Michael Naumann, Michael Vieth

03-06-2026

https://doi.org/10.4081/ejh.2026.4570

262

PDF: 176

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Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan

11-11-2022

https://doi.org/10.4081/ejh.2022.3563

1877

PDF: 927

Supplementary: 153

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LncRNA GClnc1 may contribute to the progression of ovarian cancer by regulating p53 signaling pathway

Hu Li, Zheng Zeng, Xiang Yang, Ye Chen, Lei He, Ting Wan

10-11-2020

https://doi.org/10.4081/ejh.2020.3166

1078

PDF: 698

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HLA-G expression and role in advanced-stage classical Hodgkin lymphoma

G. Caocci, M. Greco, D. Fanni, G. Senes, R. Littera, S. Lai, P. Risso, C. Carcassi, G. Faa, G. La Nasa

11-04-2016

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2753

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Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer

J. Ning, J. Zhang, W. Liu, Y. Lang, Y. Xue, S. Xu

e46

30-11-2012

https://doi.org/10.4081/ejh.2012.e46

2623

PDF: 807

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P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY S. Blando¹, E. Boschetti¹, I. Neri¹, L. Caporali², C. Fiorini², D. Ormanbekova², C. Malagelada³, I. Rusciano¹, V. Carelli², R. De Giorgio⁴, L. Manzoli¹, S. Ratti¹ | ¹Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Italy; ²IRCCS Institute of Neurological Sciences of Bologna, Neurogenetics Program, Bologna, Italy; ³Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; ⁴Department of Translational Medicine, University of Ferrara, Ferrara, Italy

21-08-2025

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189
SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

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28-12-2023

https://doi.org/10.4081/ejh.2023.3899

1218

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