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circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao

22-08-2025

https://doi.org/10.4081/ejh.2025.4230

383

PDF: 303

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microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu

10-05-2022

https://doi.org/10.4081/ejh.2022.3333

1790

PDF: 914

HTML: 31
miR-19a targeting CLCA4 to regulate the proliferation, migration, and invasion of colorectal cancer cells

Huiwen Li, Bo Huang

10-03-2022

https://doi.org/10.4081/ejh.2022.3381

2083

PDF: 707

HTML: 28
Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du

05-05-2025

https://doi.org/10.4081/ejh.2025.4178

927

PDF: 400

Supplementary: 52

HTML: 50
MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9

Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen

12-01-2022

https://doi.org/10.4081/ejh.2022.3275

2030

PDF: 811

Supplementary: 153

HTML: 37
miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen

07-04-2025

https://doi.org/10.4081/ejh.2025.4161

1532

PDF: 479

HTML: 30
Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong

17-04-2025

https://doi.org/10.4081/ejh.2025.4176

1402

PDF: 613

Supplementary: 113

HTML: 46
miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi

23-09-2025

https://doi.org/10.4081/ejh.2025.4238

437

PDF: 350

HTML: 13
MiR-130a-5p contributed to the progression of endothelial cell injury by regulating FAS

Wei Wang, Wenbo Tang, Erbo Shan, Lei Zhang, Shiyuan Chen, Chaowen Yu, Yong Gao

31-05-2022

https://doi.org/10.4081/ejh.2022.3342

1160

PDF: 725

HTML: 31
MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo

21-06-2022

https://doi.org/10.4081/ejh.2022.3426

1484

PDF: 832

HTML: 27
Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou

22-06-2022

https://doi.org/10.4081/ejh.2022.3394

1979

PDF: 1290

HTML: 29
miR-29a-3p enhances the radiosensitivity of oral squamous cell carcinoma cells by inhibiting ADAM12

Cuihong Jiang, Feng Liu , Shuai Xiao, Lili He, Wenqiong Wu, Qi Zhao

27-09-2021

https://doi.org/10.4081/ejh.2021.3295

1376

PDF: 922

HTML: 29
Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui

15-02-2022

https://doi.org/10.4081/ejh.2022.3316

1862

PDF: 745

HTML: 29
Long non-coding RNA WAC antisense RNA 1 mediates hepatitis B virus replication in vitro by reinforcing miR-192-5p/ATG7-induced autophagy

Minkai Cao, Deping Yuan, Hongxiu Jiang, Guanlun Zhou, Chao Chen, Guorong Han

02-09-2022

https://doi.org/10.4081/ejh.2022.3438

1518

PDF: 912

HTML: 46
miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan

07-12-2021

https://doi.org/10.4081/ejh.2021.3237

1539

PDF: 580

HTML: 27
miRNA-877-5p inhibits malignant progression of prostate cancer by directly targeting SSFA2

Wanchun Wang, Jun Yi, Degang Dong, Wenli Mao, Xuanyu Wang, Zhangren Yan

20-09-2021

https://doi.org/10.4081/ejh.2021.3243

1387

PDF: 680

HTML: 41
IncRNA MAPKAPK5-AS1 promotes proliferation and migration of thyroid cancer cell lines by targeting miR-519e-5p/YWHAH

Yan Zhou, Shanshan Liu, Yan Luo, Meiying Zhang, Xueling Jiang, Yan Xiong

03-12-2020

https://doi.org/10.4081/ejh.2020.3177

2131

PDF: 886

HTML: 13
Activation of Hedgehog pathway by circEEF2/miR-625-5p/TRPM2 axis promotes prostate cancer cell proliferation through mitochondrial stress

ChenHui Zhu, LiJuan Lin, ChangQing Huang, ZhiHui Wu

11-11-2024

https://doi.org/10.4081/ejh.2024.4063

1598

PDF: 562

HTML: 20
Sodium hyaluronate promotes proliferation, autophagy, and migration of corneal epithelial cells by downregulating miR-18a in the course of corneal epithelial injury

Yingzhuo Guo, Hua Wang

15-06-2023

https://doi.org/10.4081/ejh.2023.3663

1371

PDF: 636

Supplementary: 124

HTML: 27
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li

22-09-2025

https://doi.org/10.4081/ejh.2025.4239

495

PDF: 341

Supplementary: 57

HTML: 20
Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao

26-07-2023

https://doi.org/10.4081/ejh.2023.3766

2051

PDF: 1286

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MiR-122-5p inhibits the epithelial mesenchymal transition of liver cancer cells by inducing hiPSCs to differentiate into hepatocyte-like cells

Qianzhe Xing, Yanjie Xu, Ying Luo, Chenglong Li, Peng Wang, Bin Kang, Chengjun Lu

06-05-2025

https://doi.org/10.4081/ejh.2025.4190

756

PDF: 400

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miR-26b regulates cell proliferation and apoptosis of CD117+CD44+ ovarian cancer stem cells by targeting PTEN

Zubiao Gao, Xiaofeng Ye, Anne Bordeaux, Stanka Hettich, Siyao Lin, Fang Han, Yan Jia

04-02-2021

https://doi.org/10.4081/ejh.2021.3186

2289

PDF: 732

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Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang

17-09-2024

https://doi.org/10.4081/ejh.2024.4034

1201

PDF: 625

HTML: 12
LncRNA FGD5-AS1 functions as an oncogene to upregulate GTPBP4 expression by sponging miR-873-5p in hepatocellular carcinoma

Nuobei Zhang, Hao Shen, Shenan Huang, Fenfen Wang, Huifang Liu, Fen Xie, Lei Jiang, Xin Chen

16-11-2021

https://doi.org/10.4081/ejh.2021.3300

1302

PDF: 659

HTML: 52
MiR-550a-3p restores damaged vascular smooth muscle cells by inhibiting thrombomodulin in an in vitro atherosclerosis model

Shiyuan Chen, Longfei Zhang, Benchi Feng, Wei Wang, Delang Liu, Xinyu Zhao, Chaowen Yu, Xiaogao Wang, Yong Gao

19-07-2022

https://doi.org/10.4081/ejh.2022.3429

1223

PDF: 661

Supplementary: 141

HTML: 39
The role of miR-143-3p/FNDC1 axis on the progression of non-small cell lung cancer

Zhanshu Ma, Qi Gao, Wenjing Xin, Lei Wang, Yan Chen, Chang Su, Songyan Gao, Ruiling Sun

03-05-2023

https://doi.org/10.4081/ejh.2023.3577

1990

PDF: 607

HTML: 36
The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li

25-11-2021

https://doi.org/10.4081/ejh.2021.3323

1894

PDF: 686

HTML: 33
Long noncoding RNA H19 accelerates tenogenic differentiation by modulating miR-140-5p/VEGFA signaling

You-Jie Liu, Hua-Jun Wang, Zhao-Wen Xue, Lek-Hang Cheang, Man-Seng Tam, Ri-Wang Li, Jie-Ruo Li, Hui-Ge Hou, Xiao-Fei Zheng

07-09-2021

https://doi.org/10.4081/ejh.2021.3297

1820

PDF: 956

Supplementary: 168

HTML: 27
Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu

17-11-2025

https://doi.org/10.4081/ejh.2025.4426

923

PDF: 496

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The role of miRNA-29b1 on the hypoxia-induced apoptosis in mammalian cardiomyocytes

Bo Dai, Hailin Liu, Dingmin Juan, Kaize Wu, Ruhao Cao

27-06-2024

https://doi.org/10.4081/ejh.2024.4021

1040

PDF: 499

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LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway

Yong Jiang, Chun-hui Xu, Ying Zhao, Yun-han Ji, Xin-tao Wang, Ying Liu

16-01-2023

https://doi.org/10.4081/ejh.2023.3526

1790

PDF: 815

HTML: 63
miR-126 targeting GOLPH3 inhibits the epithelial-mesenchymal transition of gastric cancer BGC-823 cells and reduces cell invasion

Jiancai Ouyang, Fuhu Song, He Li, Rui Yang, Haicheng Huang

28-10-2020

https://doi.org/10.4081/ejh.2020.3168

1467

PDF: 637

HTML: 26
miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

Nan Xu, Ang-Di Li, Li-Li Ji, Yao Ye, Zhen-Yu Wang, Lei Tong

03-05-2019

https://doi.org/10.4081/ejh.2019.3008

2928

PDF: 1213

HTML: 21
Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cells via miR-6739-5p modulation and PI3K/AKT pathway activation: a functional histocytochemical study

Zefeng Sun, Xinrong Fan, Zhenquan Liu

02-10-2025

https://doi.org/10.4081/ejh.2025.4253

391

PDF: 351

HTML: 40
An emerging potential therapeutic target for osteoporosis: LncRNA H19/miR-29a-3p axis

Ziqi Li, Zhinan Hong, Yuesheng Zheng, Yongwei Dong, Wei He, Yingjia Yuan, Junbiao Guo

06-11-2020

https://doi.org/10.4081/ejh.2020.3155

1585

PDF: 740

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MicroRNA-29b-3p promotes 5-fluorouracil resistance via suppressing TRAF5-mediated necroptosis in human colorectal cancer

Shuimei Wu, Yun Zhou, Ping Liu, Hui Zhang, Wanliang Wang, Yuan Fang, Xiang Shen

22-06-2021

https://doi.org/10.4081/ejh.2021.3247

2078

PDF: 1007

Supplementary: 203

HTML: 21
Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

Dajie Wang, Zhaofeng Zhou, Liang Yuan

20-09-2022

https://doi.org/10.4081/ejh.2022.3505

1320

PDF: 606

HTML: 44
Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells via regulation of miR-1234/TP53I11 axis

Jinbi Xie, Yong Ning, Lihang Zhang, Yuan Lin, Runsheng Guo, Shanjuan Wang

03-10-2022

https://doi.org/10.4081/ejh.2022.3477

2019

PDF: 659

HTML: 43
Deletion of osteopontin in non-small cell lung cancer cells affects bone metabolism by regulating miR-34c/Notch1 axis: a clue to bone metastasis

Jing Guo, Chang-Yong Tong, Jian-Guang Shi, Xin-Jian Li, Xue-Qin Chen

26-07-2023

https://doi.org/10.4081/ejh.2023.3631

1365

PDF: 760

HTML: 27
Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li

17-05-2023

https://doi.org/10.4081/ejh.2023.3612

1400

PDF: 928

Supplementary: 100

HTML: 24
Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li

25-10-2022

https://doi.org/10.4081/ejh.2022.3529

1763

PDF: 830

HTML: 38
Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng

02-10-2023

https://doi.org/10.4081/ejh.2023.3839

1437

PDF: 814

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MicroRNA-22 enhances the differentiation of mouse induced pluripotent stem cells into alveolar epithelial type II cells

Fan Tao, Feng Wang, Weichen Zhang, Yaming Hao

01-10-2020

https://doi.org/10.4081/ejh.2020.3170

1503

PDF: 592

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Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai

14-10-2022

https://doi.org/10.4081/ejh.2022.3510

1306

PDF: 681

HTML: 38
LncRNA FBXO18-AS promotes gastric cancer progression by TGF-β1/Smad signaling

Yiming Zhang, Wanqiong Zheng, Liang Zhang, Yechun Gu, Lihe Zhu, Yingpeng Huang

20-06-2023

https://doi.org/10.4081/ejh.2023.3667

1220

PDF: 651

Supplementary: 97

HTML: 26
P42 | PANCREATIC CANCER STEM CELLS AND FUNCTIONAL CHARACTERIZATION OF MIR-216A-5P G. Fenu¹, C.G. Lison², F. Etzi³, A. Pisano³, C. Farace³, A. Sabalic³, D. Tutedde³, J.A. Marchal⁴, R. Madeddu⁵ | ¹Department of Biomedical Science, University of Sassari, 07100 Sassari, Italy; ²Instituto de Investigación Biosanitaria ibs.GRANADA, University Hospitals of Granada-University of Granada, Granada, Spain; ³Department of Biomedical Science, University of Sassari, Sassari, Italy; ⁴Instituto de Investigación Biosanitaria ibs. GRANADA, University Hospitals of Granada-University of Granada, Granada, Spain; ⁵Department of Biomedical Science, University of Sassari, Sassari, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4364

180
Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera

20-04-2022

https://doi.org/10.4081/ejh.2022.3409

1804

PDF: 929

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Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells

Yinping Zeng, Jiajun Huang, Tingting Duan, Xiaofeng Wang

28-05-2026

https://doi.org/10.4081/ejh.2026.4540

226

PDF: 163

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P19 | IDENTIFICATION OF MIR-129-5P AS A COMMON REGULATOR OF E3 UBIQUITIN LIGASES WITH A POTENTIAL ROLE IN GLIOBLASTOMA PROGRESSION N. Martella¹, A.B. Díaz Méndez², G. Regazzo², G.F. Bufalieri³, A. Frati⁴, A. Arcella⁴, L. Di Marcotullio³, M.G. Rizzo², S. Di Bartolomeo¹ | ¹Dept. of Biosciences and Territory, University of Molise, Italy; ²Dept. of Research, Advanced Diagnostics and Technological Innovation, Translational Oncology Research Unit, IRCCS -Regina Elena National Cancer Institute, Rome, Italy; ³Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy; ⁴IRCCS Neuromed, Pozzilli (IS), Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4715

3

PDF: 0
New bitongling (NBTL) ameliorates rheumatoid arthritis in rats through inhibiting JAK2/STAT3 signaling pathway

Xiang Li, Yu Xie, An Kang, Yue Wang

17-02-2021

https://doi.org/10.4081/ejh.2021.3202

2483

PDF: 982

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LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu

31-05-2023

https://doi.org/10.4081/ejh.2023.3535

1163

PDF: 651

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P30 | NEW INSIGHT IN THE IN VITRO-GENERATION OF INSULIN-PRODUCING CELLS: VAV1 AS A REGULATOR OF PDX1 AND MIR-375 LEVELS DURING DIFFERENTIATION OF HIPSCS INTO Β-CELLS M. Pierantoni¹, F. Brugnoli¹, V. Zamarian², M. Dell’Aira¹, V. Sordi², V. Bertagnolo¹, S. Grassilli³ | ¹Department of Translational Medicine, University of Ferrara, Ferrara, Italy; ²Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy; ³Department of Environmental and Prevention Sciences and LTTA Centre, University of Ferrara, Ferrara, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4350

174
Twenty years of histochemistry in the third millennium, browsing the scientific literature

Carlo Pellicciari

29-12-2020

https://doi.org/10.4081/ejh.2020.3213

1375

PDF: 539

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NOP14 regulates the growth, migration, and invasion of colorectal cancer cells by modulating the NRIP1/GSK-3β/β-catenin signaling pathway

Xuanjin Zhu, Weilu Jia, Yong Yan, Yong Huang, Bailin Wang

02-07-2021

https://doi.org/10.4081/ejh.2021.3246

2868

PDF: 778

HTML: 39
Contribution of intestinal smooth muscle to Crohn's disease fibrogenesis

C. Severi, R. Sferra, A. Scirocco, A. Vetuschi, N. Pallotta, A. Pronio, R. Caronna, G. Di Rocco, E. Gaudio, E. Corazziari, P. Onori

17-12-2014

https://doi.org/10.4081/ejh.2014.2457

2951

PDF: 1152

HTML: 436
63 | EVOLUTIONARY STRATEGIES OF CARDIAC GROWTH: THE ICEFISH HEART AS A MODEL TO CONTRAST PATHOLOGICAL CELLULAR MALADAPTATION N. Romano¹, R. Gaetani², M. Gerdol³, C. Bidoli³, M. Mercola4 E. Messina² | ¹Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; ²Dept. of Molecular Medicine, Sapienza University, Rome, Italy; ³Dept. of Life Sciences, University of Trieste, Italy; ⁴Dept. of Medicine and Cardiovascular Institute, Stanford University, Palo Alto, CA, USA

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4681

16

PDF: 7
Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

Nan Li, Xue Fan, Lihong Liu, Yanbing Liu

27-07-2023

https://doi.org/10.4081/ejh.2023.3506

1741

PDF: 1072

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Effects of rutin on osteoblast MC3T3-E1 differentiation, ALP activity and Runx2 protein expression

Xin-Wei Liu, Bin Ma, Ying Zi, Liang-Bi Xiang, Tian-Yu Han

20-01-2021

https://doi.org/10.4081/ejh.2021.3195

3197

PDF: 1501

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Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats

Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng

12-01-2022

https://doi.org/10.4081/ejh.2022.3328

2235

PDF: 1281

HTML: 99
Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang

01-08-2023

https://doi.org/10.4081/ejh.2023.3784

1951

PDF: 883

HTML: 23
Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye

30-09-2021

https://doi.org/10.4081/ejh.2021.3224

3513

PDF: 1903

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Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1245

PDF: 591

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CAPTURE-CAPIVASERTIB AND PROSTATE CANCER TARGETING: UNRAVELING RESISTANCE ELEMENTS M. Zavatti¹, V. Serafin¹, L. Antolini¹, S. Bresolin², L. Reggiani Bonetti³, S. Marmiroli¹ | ¹Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy; ²Pediatric Hematology, Oncology and Stem Cell Transplant Division, Women and Child Health Department, Padua University, Padua, Italy; ³Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia, Modena, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4277

204
Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea

Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong

01-09-2023

https://doi.org/10.4081/ejh.2023.3704

1181

PDF: 951

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Lobetyolin suppressed lung cancer in a mouse model by inhibiting epithelial-mesenchymal transition

Lu Liu, Zhankui Liu, Liu Yang, Xue Wu, Jiaying Zhu, Lili Liu, Yang Liu

04-07-2022

https://doi.org/10.4081/ejh.2022.3423

2151

PDF: 900

HTML: 81
Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li

22-07-2024

https://doi.org/10.4081/ejh.2024.4048

2368

PDF: 1316

HTML: 22
Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway

Zhongzhu Tang, Lei Wang, Yunwang Chen, Xiaomin Zheng, Runyu Wang, Bingxue Liu, Shiqi Zhang, Huimin Wang

07-08-2023

https://doi.org/10.4081/ejh.2023.3719

1934

PDF: 906

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Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

Jun Lin, Liping Jiang, Kun Guo, Ning Feng

22-12-2022

https://doi.org/10.4081/ejh.2023.3528

2013

PDF: 1229

Supplementary: 134

HTML: 39
Umbilical cord mesenchymal stem cells inhibited inflammation of bronchial epithelial cells by regulating Hedgehog pathway

Qiong Lin, Tianxing Yu, Xiaohua Li, Xin Lin, Yong Fan, Liyu Xu

12-12-2023

https://doi.org/10.4081/ejh.2023.3908

1617

PDF: 513

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Effects of Notch signaling on proliferation, angiogenesis, and adipogenesis of hemangioma-derived stem cells

Weidong Wang, Sheng Chen, Yuan Wang, Cui Jie, Weimin Shen

01-09-2025

https://doi.org/10.4081/ejh.2025.4241

529

PDF: 409

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Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang

08-09-2023

https://doi.org/10.4081/ejh.2023.3742

1169

PDF: 483

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Bovine pericardium membrane, gingival stem cells, and ascorbic acid: a novel team in regenerative medicine

Jacopo Pizzicannella, Guya D. Marconi, Sante D. Pierdomenico, Marcos F.X.B. Cavalcanti, Francesca Diomede, Oriana Trubiani

25-09-2019

https://doi.org/10.4081/ejh.2019.3064

1708

PDF: 840

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Neurokinin-1 receptor is highly expressed in cervical cancer and its antagonist induces cervical cancer cell apoptosis

Liyun Guan, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang

11-01-2023

https://doi.org/10.4081/ejh.2023.3570

1472

PDF: 698

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Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability

Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan

07-12-2021

https://doi.org/10.4081/ejh.2021.3352

1762

PDF: 783

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Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang

07-12-2023

https://doi.org/10.4081/ejh.2023.3816

1210

PDF: 698

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Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang

01-09-2025

https://doi.org/10.4081/ejh.2025.4217

533

PDF: 213

HTML: 11
Quantitative, structural and molecular changes in neuroglia of aging mammals: A review

Ennio Pannese

23-06-2021

https://doi.org/10.4081/ejh.2021.3249

1724

PDF: 856

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Aberrant expression of CCDC69 in breast cancer and its clinicopathologic significance

Jinjiao Li, Panshi Zhang, Yun Xia

22-02-2021

https://doi.org/10.4081/ejh.2021.3207

1569

PDF: 861

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DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu

22-12-2022

https://doi.org/10.4081/ejh.2023.3413

1276

PDF: 648

Supplementary: 109

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SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu

03-03-2026

https://doi.org/10.4081/ejh.2026.4530

493

PDF: 386

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Correlation of the AKT/mTOR signaling pathway with the clinicopathological features and prognosis of nasopharyngeal carcinoma

Yan Wang, Jie Sun, Ninghua Yao

16-11-2021

https://doi.org/10.4081/ejh.2021.3304

1707

PDF: 624

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Ferritin expression in the periodontal tissues of primates

Wenxue Huang, Wei Li, Juan Liu, Jianxia Hou, Huanxin Meng

03-09-2019

https://doi.org/10.4081/ejh.2019.3046

1325

PDF: 729

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Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li

21-01-2025

https://doi.org/10.4081/ejh.2025.4158

1840

PDF: 589

Supplementary Figure: 89

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LncRNA GClnc1 may contribute to the progression of ovarian cancer by regulating p53 signaling pathway

Hu Li, Zheng Zeng, Xiang Yang, Ye Chen, Lei He, Ting Wan

10-11-2020

https://doi.org/10.4081/ejh.2020.3166

1008

PDF: 657

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Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang

11-05-2023

https://doi.org/10.4081/ejh.2023.3653

1234

PDF: 660

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Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally

Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariotti

04-07-2024

https://doi.org/10.4081/ejh.2024.4040

2050

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Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou

02-12-2021

https://doi.org/10.4081/ejh.2021.3331

2597

PDF: 1485

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Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang

29-04-2024

https://doi.org/10.4081/ejh.2024.4019

1903

PDF: 613

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Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan

11-11-2022

https://doi.org/10.4081/ejh.2022.3563

1654

PDF: 872

Supplementary: 129

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Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié

21-08-2025

https://doi.org/10.4081/ejh.2025.4174

608

PDF: 402

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Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin

23-10-2024

https://doi.org/10.4081/ejh.2024.4098

2302

PDF: 495

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Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: a clue to enhance endometrial receptivity in recurrent implantation failure

Haixia Li, Ning Sun, Yaqiao Zhu, Wei Wang, Meihong Cai, Xiaohuan Luo, Wei Xia, Song Quan

22-12-2022

https://doi.org/10.4081/ejh.2023.3580

1652

PDF: 972

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Immunohistochemical analysis of YB-1 expression in the developing mouse eye

Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass

03-11-2025

https://doi.org/10.4081/ejh.2025.4244

1533

PDF: 251

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SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang

18-05-2026

https://doi.org/10.4081/ejh.2026.4544

163

PDF: 126

Supplementary: 21

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Inhibition of APLN suppresses cell proliferation and migration and promotes cell apoptosis in esophageal cancer cells in vitro, through activating PI3K/mTOR signaling pathway

Yuhan Wang, Gang Wang, Xiaojun Liu, Dong Yun, Qing Cui, Xiaoting Wu, Wenfeng Lu, Xiwen Yang, Ming Zhang

03-08-2022

https://doi.org/10.4081/ejh.2022.3336

1564

PDF: 769

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Optimization of the autophagy measurement in a human cell line and primary cells by flow cytometry

Tonino Alonzi, Elisa Petruccioli, Valentina Vanini, Gian Maria Fimia, Delia Goletti

26-06-2019

https://doi.org/10.4081/ejh.2019.3044

2108

PDF: 1227

Supplementary: 194

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High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari

16-12-2024

https://doi.org/10.4081/ejh.2024.4145

1362

PDF: 421

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Phosphorylation mutation impairs the promoting effect of spastin on neurite outgrowth without affecting its microtubule severing ability

Yunlong Zhang, Xin He, Jianyu Zou, Jie Yang, Ao Ma, Minghui Tan

12-01-2023

https://doi.org/10.4081/ejh.2023.3594

1476

PDF: 787

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Expression and clinical significance of HER2/neu, aromatase P450 and adhesion molecule CD24 in endometrial cancer

Liyun Guan, Ying Wang, Jianxin Cheng, Jun Zhang, Shan Kang

10-08-2023

https://doi.org/10.4081/ejh.2023.3655

1177

PDF: 594

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