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Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species
2185PDF: 1102Supplementary: 104HTML: 125 -
EXPRESSION OF PIEZO1 IN CLEAR CELL RENAL CELL CARCINOMA: INSIGHTS FROM BIOINFORMATIC AND IMMUNOHISTOCHEMICAL ANALYSES D. Jerka1, P. Antosik2, K. Bonowicz1,3, D. Grzanka4, M. Gagat1,3 | 1Department of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland; 2Department of Dermatology and Venerology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland; 3Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Płock, Poland; 4Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland
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P84 | OMOMYC PEPTIDE LOCALIZES IN THE NUCLEUS AND DISPLAYS ANTIPROLIFERATIVE EFFECTS ON CELLULAR MODELS OF HUMAN OSTEOSARCOMA I. Versari1, S. Salucci1, A. Bavelloni2, M. Traversari3, I. Faenza1 | 1Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy; 2Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; 3Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
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P45 | TARGETING PRELAMIN A PROCESSING TO SENSITIZE GLIOBLASTOMA CELLS TO OXIDATIVE STRESS M.V. Marvi1, C. Evangelisti1, I. Rusciano1, I. Neri1, L.I. Cocco1, L. Manzoli1, C. Capanni2, S. Ratti1 | 1Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum-University of Bologna, Bologna, Italy; 2CNR Institute of Molecular Genetics «Luigi Luca Cavalli-Sforza», Unit of Bologna, Bologna, Italy / IRCCS Rizzoli Orthopedi, Institute, Bologna, Italy
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Expression of nestin, parvalbumin and otoferlin during cochlear development in the mouse: an immunofluorescence study
558PDF: 420Supplementary: 43HTML: 8 -
P09 | EFFECTS OF NUTLIN-3A ACTIVITY ON 2D AND 3D RETINOBLASTOMA MODELS F. Bompan1, R. Foschi2, A. Dipinto3, F. Casciano2, G. Lodi4, A. Sanvido5, P. Severi4, L. Giari1, L. C. Cosenza5, R. Voltan2, A. Romani4 | 1Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; 2Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; 3Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; 4Department of Translational Medicine, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; 5Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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ANIMAL MODELS OF METASTATIC CANCER - ADVANCED IMAGE ANALYSIS FOR DISSECTION OF DRIVING SIGNALING PATHWAYS S. Alberti | University of Messina, Messina, Italy
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Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway
1750PDF: 567Supplementary Figure: 79HTML: 53 -
P50 | OPTIMIZATION OF A RAPID AND EFFICIENT DECELLULARIZATION PROTOCOL FOR COMPOSITE VASCULARIZED FACIAL GRAFT FABRICATION A. Menini1, A. M. Sacco1, V. Romano1, D. Nurzynska2, G. Ricci3, S. La Padula1, F. Schonauer1, C. Castaldo1, F. Di Meglio1 | 1Department of Public Health, University of Naples «Federico II», Naples, Italy; 2Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy; 3Department of Experimental Medicine, University of Campania «Luigi Vanvitelli», Naples, Italy
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Expression pattern of thymosin beta 4 in the adult human liver
1544PDF: 696HTML: 1350 -
P25 | RESPONSE TO HEDGEHOG AND PI3K/AKT/MTOR PATHWAY INHIBITORS IN PREB-ALL: ANALYSIS OF THE INTRACELLULAR DISTRIBUTION OF PATHWAY ENZYMES AND OF THE AUTOPHAGY PROCESS M. Sicurella1, M. De Chiara2, E. Battaglia2, F. Franco2, M. De Vita2, L.M. Neri2 | 1Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; 2Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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MORPHOLOGICAL AND SYNAPTIC CHANGES OF THE CORTICAL GABAERGIC INHIBITORY SYSTEM IN SPINAL MUSCULAR ATROPHY Menduti G1,2, Ferrini F3,4, Caretto A1,2, Hassan A5,6, di Vito R6,7, Beltrando G1,2, Marnetto D2, Usiello A6,7, Di Cunto F1,2, Boido M1,2, and Vercelli A1,2 | 1Neuroscience Institute Cavalieri Ottolenghi, Orbassano, Turin, Italy; 2Department of Neuroscience «Rita Levi Montalcini», University of Turin, Italy; 3Department of Veterinary Sciences, University of Turin, Grugliasco, Turin, Italy; 4Department of Psychiatry and Neuroscience, Université Laval, Québec, Canada; 5European School of Molecular medicine, University of Milan, Italy; 6Laboratory of Translational Neuroscience, Ceinge Biotecnologie Avanzate, Naples, Italy; 7Department of Environmental, Biological and Pharmaceutical Science and Technologies, Università degli Studi della Campania Luigi Vanvitelli, Caserta, Italy
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Sox9 expression in canine epithelial skin tumors
3121PDF: 862HTML: 406 -
ROLE OF MITOCHONDRIAL METABOLISM AND CONTACT SITES IN CANCER CELL DEATH AND SURVIVAL F. Severin, A. Ruzza, F. Vianello, E. Zaltron, I. Celotti, M. Scavezzon, S. Toffanin, C. Bastianello, L. Leanza | Department of Biology, University of Padova, Padova, Italy
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P62 | FFAR4/GPR120 ACTIVATION COUNTERACTS FIBROGENIC PATHWAYS IN A CHOLESTATIC LIVER INJURY MODEL S. Pompili1, R. Sferra1, F. Ronca1, A. Cappariello2, A. Vetuschi1 | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy; 2Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy
253 -
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells
443PDF: 303Supplementary: 43HTML: 17 -
P27 | HISTOCHEMICAL APPROACHES FOR EVALUATING THE REPRODUCTIVE HEALTH OF MUSSEL MYTILUS GALLOPROVINCIALIS EXPOSED TO ACUTE THERMAL STRESS M. Galati, M. A. Oueldi, M. Romeo, T. Cappello, M. Maisan | Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy
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EXPLORING NEURON–GLIOMA SIGNALING THROUGH IN VITRO CO-CULTURES Nicorvo E¹, Ferraro A¹, Pacca P¹, Boido M¹, Di Cunto F¹ and Vercelli A¹ | ¹Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy
216 -
FLOW CYTOMETRY IN THE DEVELOPMENT AND CHARACTERIZATION OF PRECLINICAL TUMOR MODELS BASED ON THE ANALYSIS OF EXTRACELLULAR VESICLES AS CANDIDATE LIQUID BIOMARKERS I. D’Agnano | Institute of Biomedical Technologies, CNR, Segrate, Milan, Italy
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Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway
1336PDF: 900Supplementary: 89HTML: 21 -
Expression of parafibromin in major renal cell tumors
1465PDF: 639HTML: 220 -
NEUROACTIVE STEROIDS PROTECT FROM BORTEZOMIB-INDUCED TOXICITY: EVIDENCE FROM IN VITRO MODELS Fabbro V1, Tonelli E1,2, Scuteri A1,3, D’Aprile C1, Naghshbandieh A1,2, Lim D4, Distasi C4, Giatti S5 and Meregalli C1 | 1School of Medicine and Surgery, Experimental Neurology Unit and Milan Center for Neuroscience, University of Milano- Bicocca, Monza, Italy; 2University of Milano-Bicocca, PhD Program in Neuroscience, Monza, Italy; 3Milan Center for Neuroscience (NeuroMI); 4University of Piemonte Orientale, Department of Pharmaceutical Sciences, Novara, Italy; 5University of Milan, Department of Pharmacological and Biomolecular Sciences “Rodolfo Paoletti”, Milan, Italy
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P80 | MITOCHONDRIA-LYSOSOME INTERACTIONS: EMERGING PLAYERS IN GLIOMA L. Zeppa1, M.B. Morelli2, C. Aguzzi2, M. Giangrossi2, M. Nabissi2, G. Cameli2, G. Santoni2, S.K. Tayebati2, V. Bellitto1, D. Tomassoni1, C. Amantini1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Pharmacy, University of Camerino, Camerino, Italy
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