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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

    Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
    17-04-2025
    https://doi.org/10.4081/ejh.2025.4176
    1297
    PDF: 561
    Supplementary: 103
    HTML: 43
  • Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

    Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin
    23-10-2024
    https://doi.org/10.4081/ejh.2024.4098
    2142
    PDF: 447
    HTML: 26
  • Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

    Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang
    01-08-2023
    https://doi.org/10.4081/ejh.2023.3784
    1849
    PDF: 838
    HTML: 20
  • Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

    Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du
    05-05-2025
    https://doi.org/10.4081/ejh.2025.4178
    819
    PDF: 362
    Supplementary: 44
    HTML: 46
  • Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

    Jun Lin, Liping Jiang, Kun Guo, Ning Feng
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3528
    1925
    PDF: 1179
    Supplementary: 122
    HTML: 37
  • Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

    Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai
    14-10-2022
    https://doi.org/10.4081/ejh.2022.3510
    1261
    PDF: 664
    HTML: 35
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    239
    PDF: 192
    HTML: 2
  • HLA-G expression and role in advanced-stage classical Hodgkin lymphoma

    G. Caocci, M. Greco, D. Fanni, G. Senes, R. Littera, S. Lai, P. Risso, C. Carcassi, G. Faa, G. La Nasa
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2606
    2601
    PDF: 792
    HTML: 232
  • E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

    Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei
    26-05-2025
    https://doi.org/10.4081/ejh.2025.4196
    1027
    PDF: 472
    HTML: 14
  • Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

    Rong Tian, Gengsheng Mao
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3350
    1770
    PDF: 855
    HTML: 36
  • Spatio-temporal course of macrophage-like cell accumulation after experimental embolic stroke depending on treatment with tissue plasminogen activator and its combination with hyperbaric oxygenation

    D. Michalski, M. Heindl, J. Kacza, F. Laignel, L. Küppers-Tiedt, D. Schneider, J. Grosche, J. Boltze, M. Löhr, C. Hobohm, W. Härtig
    e14
    09-05-2012
    https://doi.org/10.4081/ejh.2012.14
    6633
    PDF: 772
    HTML: 10442
  • Assessing the interactions between nanoparticles and biological barriers in vitro: a new challenge for microscopy techniques in nanomedicine

    Flavia Carton, Manuela Malatesta
    24-11-2022
    https://doi.org/10.4081/ejh.2022.3603
    999
    PDF: 443
    HTML: 19
  • Targeting EphA2 suppresses the proliferation, migration and invasion of endometriosis via the AMPK signaling pathway

    Chaoyi Yang, Shujun Wang, Mengru Li, Xiangli Pang, Aili Tan
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4168
    501
    PDF: 309
    HTML: 13
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    2925
    PDF: 1145
    Supplementary: 377
    HTML: 1013
  • Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma

    Zhiyang Wang, Jing Li, Ziwei Liu, Ling Yue
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3622
    1176
    PDF: 729
    HTML: 34
  • Reliable hexokinase 3 protein detection in human cell lines and primary tissue

    Yasmeen H. Mady, Carmen G. Kalbermatter, Maarij Khan, Anna M. Schläfli, Rina Mehmeti, Inti Zlobec, Lucine Christe, Mario P. Tschan
    12-03-2025
    https://doi.org/10.4081/ejh.2025.4175
    1685
    PDF: 429
    Supplementary: 51
    Uncropped Western blots: 50
    HTML: 10
  • Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

    Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu
    17-11-2025
    https://doi.org/10.4081/ejh.2025.4426
    719
    PDF: 431
    HTML: 15
  • Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

    Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang
    01-09-2025
    https://doi.org/10.4081/ejh.2025.4217
    487
    PDF: 186
    HTML: 8
  • Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

    V.N. Karavana, H. Gakiopoulou, E.A. Lianos
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2308
    2188
    PDF: 874
    HTML: 645
  • Elastofibroma dorsi: a histochemical and immunohistochemical study

    A. Di Vito, E. Scali, G. Ferraro, C. Mignogna, I. Presta, C. Camastra, C. Palmieri, G. Donato, T. Barni
    19-02-2015
    https://doi.org/10.4081/ejh.2015.2459
    2676
    PDF: 872
    HTML: 1097
  • CCL18 promotes endometriosis by increasing endometrial cell migration and neuroangiogenesis

    Yangying Peng, Shaojie Ding, Ping Xu, Xueyan Zhang, Jianzhang Wang, Tiantian Li, Liyun Liao, Xinmei Zhang
    06-08-2024
    https://doi.org/10.4081/ejh.2024.4052
    985
    PDF: 680
    HTML: 37
  • Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

    A.M. Schläfli, S. Berezowska, O. Adams, R. Langer, M.P. Tschan
    05-05-2015
    https://doi.org/10.4081/ejh.2015.2481
    7969
    PDF: 3226
    HTML: 2144
  • Treatment of diabetic foot ulcers with Therapeutic Magnetic Resonance (TMR®) improves the quality of granulation tissue

    Letizia Ferroni, Chiara Gardin, Andrea De Pieri, Maria Sambataro, Elena Seganfreddo, Chiara Goretti, Elisabetta Iacopi, Barbara Zavan, Alberto Piaggesi
    07-08-2017
    https://doi.org/10.4081/ejh.2017.2800
    2202
    PDF: 998
    HTML: 128
  • LOX-1 deficient mice show resistance to zymosan-induced arthritis

    Kazuhiko Hashimoto, Yutaka Oda, Koichi Nakagawa, Terumasa Ikeda, Kazuhiro Ohtani, Masao Akagi
    22-01-2018
    https://doi.org/10.4081/ejh.2018.2847
    2007
    PDF: 852
    HTML: 74
  • Vitamin D and vitamin D receptor in patients with ophthalmic pterygium

    Cristina Maxia, Daniela Murtas, Michela Corrias, Ignazio Zucca, Luigi Minerba, Franca Piras, Cristiana Marinelli, Maria Teresa Perra
    30-10-2017
    https://doi.org/10.4081/ejh.2017.2837
    1898
    PDF: 989
    HTML: 73
  • Umbilical cord mesenchymal stem cells inhibited inflammation of bronchial epithelial cells by regulating Hedgehog pathway

    Qiong Lin, Tianxing Yu, Xiaohua Li, Xin Lin, Yong Fan, Liyu Xu
    12-12-2023
    https://doi.org/10.4081/ejh.2023.3908
    1545
    PDF: 486
    HTML: 23
  • Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation

    Hongkai Xiao, Jinghu Liu, Qinhong Cai, Siyu Liang, Zhitao Hu, Xiaochao Chen
    13-10-2025
    https://doi.org/10.4081/ejh.2025.4254
    505
    PDF: 347
    HTML: 38
  • Pleural mesothelioma from fluoro-edenite exposure: PACAP and PAC1 receptor. A preliminary report

    Claudia Lombardo, Grazia Maugeri, Agata Grazia D'Amico, Giuseppe Broggi, Rosario Caltabiano, Veronica Filetti, Serena Matera, Velia D'Agata, Carla Loreto
    02-05-2024
    https://doi.org/10.4081/ejh.2024.3994
    1469
    PDF: 437
    HTML: 29
  • The knee joint loose body as a source of viable autologous human chondrocytes

    J. Melrose
    10-06-2016
    https://doi.org/10.4081/ejh.2016.2645
    2254
    PDF: 771
    HTML: 406
  • Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

    Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4218
    1090
    PDF: 487
    HTML: 23
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    883
    PDF: 457
    HTML: 48
  • Differential expression patterns of N-acetylglucosaminyl transferases and polylactosamines in uterine lesions

    A.T.R. Clark, V.M.L. Guimaraes da Costa, L. Bandeira Costa, C.L. Bezerra Cavalcanti, M.J.B. de Melo Rego, E.I.C. Beltrao
    26-05-2014
    https://doi.org/10.4081/ejh.2014.2334
    2407
    PDF: 1740
    HTML: 400
  • Swertianolin ameliorates immune dysfunction in sepsis via blocking the immunosuppressive function of myeloid-derived suppressor cells

    Zongfang Ren, Haoren Tang, Linjun Wan, Xing Liu, Ning Tang, Lingling Wang, Zhenhui Guo
    01-09-2021
    https://doi.org/10.4081/ejh.2021.3292
    1429
    PDF: 931
    HTML: 31
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    2954
    PDF: 1661
    Video 1: 230
    Video 2: 273
    HTML: 25
  • Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

    Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang
    29-04-2024
    https://doi.org/10.4081/ejh.2024.4019
    1814
    PDF: 575
    HTML: 21
  • Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

    Chixian Zhang, Kai Bai, Dexu Li
    14-04-2025
    https://doi.org/10.4081/ejh.2025.4186
    1226
    PDF: 453
    HTML: 28
  • Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats

    Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3328
    2145
    PDF: 1244
    HTML: 89
  • Expression pattern of thymosin beta 4 in the adult human liver

    S. Nemolato, P. Van Eyken, T. Cabras, F. Cau, M.U. Fanari, A. Locci, D. Fanni, C.L.P. Gerosa, I. Messana, M. Castagnola, G. Faa
    e25
    07-09-2011
    https://doi.org/10.4081/ejh.2011.e25
    1535
    PDF: 692
    HTML: 1350
  • Developmental characteristics of cutaneous telocytes in late embryos of the silky fowl

    Hao Li, Junliang Chen, Wenjun You, Yizhen Xu, Yaqiong Ye, Haiquan Zhao, Junxing Li, Hui Zhang
    15-10-2024
    https://doi.org/10.4081/ejh.2024.4089
    1620
    PDF: 348
    HTML: 9
  • Immunoreactivity of thymosin beta 4 in human foetal and adult genitourinary tract

    S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, D. Fanni, C. Gerosa, B. Manconi, I. Messana, M. Castagnola, G. Faa
    e43
    13-10-2010
    https://doi.org/10.4081/ejh.2010.e43
    1439
    PDF: 568
    HTML: 955
  • Deubiquitinase USP14 is upregulated in Crohn's disease and inhibits the NOD2 pathway mediated inflammatory response in vitro

    Mengling Li, Yan Zhao, Jiayi Zhang, Wang Jiang, Siyuan Peng, Jinyue Hu, Yueming Shen
    09-09-2024
    https://doi.org/10.4081/ejh.2024.4101
    1227
    PDF: 411
    HTML: 12
  • Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

    Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié
    21-08-2025
    https://doi.org/10.4081/ejh.2025.4174
    523
    PDF: 314
    HTML: 16
  • Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

    Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3391
    3439
    PDF: 1870
    HTML: 53
  • Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

    R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2547
    1819
    PDF: 1038
    HTML: 355
  • Immunohistochemical markers of neural progenitor cells in the early embryonic human cerebral cortex

    L. Vinci, A. Ravarino, V. Fanos, A.G. Naccarato, G. Senes, C. Gerosa, G. Bevilacqua, G. Faa, R. Ambu
    01-02-2016
    https://doi.org/10.4081/ejh.2016.2563
    4488
    PDF: 2452
    HTML: 1527
  • Expression of hyaluronan synthase 3 in deformed human temporomandibular joint discs: in vivo and in vitro studies

    T. Matsumoto, M. Inayama, I. Tojyo, N. Kiga, S. Fujita
    e50
    15-12-2010
    https://doi.org/10.4081/ejh.2010.e50
    1659
    PDF: 669
    HTML: 1277
  • Identification of 5-hydroxytryptamine-producing cells by detection of fluorescence in paraffin-embedded tissue sections

    Y. Kaneko, N. Onda, Y. Watanabe, M. Shibutani
    29-09-2016
    https://doi.org/10.4081/ejh.2016.2684
    2159
    PDF: 813
    HTML: 310
  • Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse

    A. Vetuschi, A. D'Alfonso, R. Sferra, D. Zanelli, S. Pompili, F. Patacchiola, E. Gaudio, G. Carta
    16-02-2016
    https://doi.org/10.4081/ejh.2016.2604
    2230
    PDF: 912
    HTML: 628
  • Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

    Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3412
    2383
    PDF: 1376
    HTML: 31
  • Curculigoside inhibits osteoarthritis via the regulation of NLRP3 pathway

    Xufei Wang, Yinlian Liu, Yongnian Zhou, Yang Zhou, Yueping Li
    13-12-2023
    https://doi.org/10.4081/ejh.2023.3896
    1347
    PDF: 653
    HTML: 18
  • Cadmium influences the 5-Fluorouracil cytotoxic effects on breast cancer cells

    Y. Asara, J. A. Marchal, P. Bandiera, V. Mazzarello, L. G. Delogu, M. A. Sotgiu, A. Montella, R. Madeddu
    e1
    20-01-2012
    https://doi.org/10.4081/ejh.2012.e1
    1798
    PDF: 895
    HTML: 4526
  • Colorimetric and fluorescent TRAP assays for visualising and quantifying fish osteoclast activity

    Lalith Prabha Ethiraj, En Lei Samuel Fong, Ranran Liu, Madelynn Chan, Christoph Winkler, Tom James Carney
    24-03-2022
    https://doi.org/10.4081/ejh.2022.3369
    2451
    PDF: 1572
    HTML: 92
  • The possible alleviating effect of garlic supplement on the neural retina in a rat model of hypercholesterolemia: a histological and immunohistochemical study

    Eetmad A. Arafat, Eman M.I. Youssef, Hanaa A. Khalaf
    16-12-2021
    https://doi.org/10.4081/ejh.2021.3322
    1203
    PDF: 523
    HTML: 21
  • Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

    Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4034
    1118
    PDF: 542
    HTML: 9
  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2156
    PDF: 1089
    Supplementary: 101
    HTML: 110
  • MyD88/ERK/NFkB pathways and pro-inflammatory cytokines release in periodontal ligament stem cells stimulated by Porphyromonas gingivalis

    Francesca Diomede, Maria Zingariello, Marcos F.X.B. Cavalcanti, Ilaria Merciaro, Jacopo Pizzicannella, Natalia de Isla, Sergio Caputi, Patrizia Ballerini, Oriana Trubiani
    24-05-2017
    https://doi.org/10.4081/ejh.2017.2791
    3188
    PDF: 1357
    HTML: 150
  • Endoplasmic reticulum stress contributed to inflammatory bowel disease by activating p38 MAPK pathway

    Yan Long, Yan Zhao, Xiaoqing Ma, Ya Zeng, Tian Hu, Weijie Wu, Chongtian Deng, Jinyue Hu, Yueming Shen
    23-05-2022
    https://doi.org/10.4081/ejh.2022.3415
    2182
    PDF: 1136
    HTML: 52
  • Non-invasive imaging demonstrates clinical features of ankylosing spondylitis in a rat adjuvant model: a case study

    N. Accart, J. Dawson, F. Kolbinger, I. Kramer, N. Beckmann
    02-11-2016
    https://doi.org/10.4081/ejh.2016.2667
    2280
    PDF: 874
    HTML: 376
  • Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

    Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang
    07-12-2023
    https://doi.org/10.4081/ejh.2023.3816
    1135
    PDF: 670
    HTML: 33
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Vol. 70 No. 2 (2026)
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European Journal of Histochemistry

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