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KAEMPFEROL TARGETS LIPID BALANCE, ENDOCANNABINOID PATHWAYS, AND PPAR-α IN THE RAT CEREBRAL CORTEX AFTER TRANSIENT BILATERAL COMMON CAROTID ARTERY OCCLUSION AND REPERFUSION Serra MP#, Carta G#, Murru E, Boi M, Manca C, Lai Y, Cabboi M, Carta A, Banni S* and Quartu M* | Department of Biomedical Sciences, University of Cagliari, Italy #equal contribution; *co-seniorship
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P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini1, S. Leone1, R. Mancinelli1, R. Vaccaro1, M. Catalano2, G. D’Alessandro2, A. Rinaldi2, A. Reccagni2, G. Vivacqua3, A. Franchitto4, P. Onori1, C. Limatola2, E. Gaudio1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; 2Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; 3Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; 4Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy
186 -
P10 | BIOLOGICAL ACTIVITIES OF CITRUS LIMON-, VITIS VINIFERA- AND ACTINIDIA DELICIOSA-DERIVED EXTRACELLULAR VESICLES ON HUMAN CACO-2 CELLS M. Destino, E. Carata, B.A. Tenuzzo, E. Panzarini | Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy
104PDF: 38 -
04 | MODULATION OF NEUROINFLAMMATION IN IL-1BETA-INDUCED HUMAN ASTROCYTES: EFFECTS OF GREEN LEAVES AND RHIZOMES EXTRACT FROM POSIDONIA OCEANICA (L.) DELILE G. Abruscato1, L. Sileo2, G. Scanavino2, C. Guerriero2, M. Mauro1, M. Vazzana1|3, V. Arizza1|3, C. Luparello1|3, A.M.Tata2 | 1Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Dept. of Biology and Biotechnologies Charles Darwin, Sapienza- University of Rome, Italy; 3National Biodiversity Future Center (NBFC), Italy
302PDF: 64 -
P21 | INVOLVEMENT OF TELOCYTES IN CARDIAC INFLAMMATION CAUSED BY LPS IN MICE AND THE POTENTIAL ANTI-INFLAMMATORY ROLE OF CANNABIS SATIVA L. A. Miller1, G.P. Lombardo2, A. Nunnari2, G. Pirracchio2, M. Kotańska3, C. Condurso4, E.R. Lauriano2, S. Pergolizzi2 | 1Dept. for the Promotion of Human Sciences and Quality of life, San Raffaele University, Rome, Italy; 2Dept. of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; 3Dept. of Pharmacological Screening, Jagiellonian University Medical; College, Kraków, Poland; 4Dept of Veterinary Sciences, University of Messina, Italy
122PDF: 49 -
MiR-550a-3p restores damaged vascular smooth muscle cells by inhibiting thrombomodulin in an in vitro atherosclerosis model
1312PDF: 728Supplementary: 150HTML: 42 -
73 | PROTECTIVE ROLE FOR OLEOYLETHANOLAMIDE IN THE HUMAN BRAIN: EFFECTS ON THE MODULATION OF NEUROINFLAMMATION AND INSULIN RESISTANCE IN HUMAN ASTROCYTES Lucia Sileo1, Giulia Scanavino1, Silvana Gaetani2, Ada MariaTata1 | 1Dept. of Biology and Biotechnologies "Charles Darwin", University of Rome "Sapienza", Rome, Italy; 2Dept. of Physiology and Pharmacology “Vittorio Erspamer”, University of Rome "Sapienza", Rome, Italy
103PDF: 50 -
P52 | MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL EVALUATION OF THE ANTI-INFLAMMATORY AND ANTIOXIDANT PROPERTIES OF HEMP EXTRACTS ON THE LIVER OF RATS INVOLVED IN INFLAMMATION CAUSED BY LPS A. Miller1, M. Kotanska2, M. Bednarski2, G.P. Lombardo3, V. Natale3, G. Pirracchio3, L. Spiccia3, S. Pergolizzi3, G. Rizzo4, E.R. Lauriano3 | 1Department of Veterinary Sciences, University of Messina, Messina, Italy; 2Department of Pharmacological Screening, Jagiellonian University Medical College, Kraków, Poland: 3Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; 4Department of Clinical and Experimental Medicine, University of Messina, Italy
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P65 | (YS) INVESTIGATING THE EFFECTS OF THE SECRETOME FROM HUMAN AMNIOTIC MESENCHYMAL STROMAL CELLS ON INFLAMMASOME ACTIVATION M. Rossi1, M. Magatti2, P. Romele2, E. Vertua2, E. Giuzzi2, S. Farigu2, L. Marelli2, B. Rapuzzi2, S. De Munari2, A. Silini2, O. Parolini3 | 1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, and Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 2Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 3Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy & Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy
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23 | BIOFUNCTIONALIZED ELECTROSPUN FIBERS FOR SKIN REGENERATION E. Coccia1, R. Imperatore1, E. Mula1|2, M. Paolucci1 | 1Dept. of Sciences and Technologies, University of Sannio, Benevento, Italy; 2Dept. of Organic and Inorganic Chemistry, University of Alcalà, Alcalà de Henares, Spain
112PDF: 43 -
The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis
1956PDF: 1012Supplementary: 205HTML: 34 -
Expression of the endocannabinoid receptors in human fascial tissue
3577PDF: 1867HTML: 2367 -
Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway
1937PDF: 643Supplementary Figure: 112HTML: 63 -
BIOLOGICAL RESPONSE OF TREATMENT WITH SAFFRON PETAL EXTRACT ON CYTOKYNE-INDUCED OXIDATIVE STRESS AND INFLAMMATION IN THE CACO-2/THP1 COCOLTURE MODEL V. Panella1, F. De Cecco2, S. Franceschelli1, M. A. Maggi3, S. Bisti4, A. Bravo Nuevo5, D. D’Ardes1, F. Cipollone1, L. Speranza1 | 1Department of Medicine and Aging Sciences, University «G. D’Annunzio», Chieti; 2Italian Institute of Technology, Genoa, Italy; 3Hortus Novus, L’Aquila, Italy; 4National Institute of Biostructure and Biosystem, Rome, Italy; 5Department of Biomedical Sciences, Philadelphia College of Osteopathic Medicine (PCOM), Philadelphia, USA
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P24 | NUTRACEUTICAL-MEDIATED EFFECTS IN THE MODULATION OF INFLAMMATORY PROCESSES IN AN IN VITRO MODEL OF HUMAN ENDOMETRIAL STROMAL CELLS L. Pietrobelli1, V.C. Divincenzo1, L. Sileo1, G. Scanavino1, E. Vicini2, L. Campagnolo3, V. Corsetti4, A.M. Tata1 | 1Dept. of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome, Italy; 2Dept. of SAIMAL, Section of Histology, Sapienza University of Rome, Italy; 3Dept. of Biomedicine and Prevention, University of Rome Tor Vergata, Italy; 4Institute of Translational Pharmacology (IFT)-CNR, Rome, Italy
75PDF: 45 -
P07 | ULVANS AS AN ECO-FRIENDLY TOOL TO MITIGATE CELLULAR IMPAIRMENT INDUCED BY DEXAMETHASONE IN MYTILUS GALLOPROVINCIALIS N. Caruso1|2, G. De Marco2, M. Galati2, La Pusata2, M. Terranova1|2, V. Parrino2, G. Genovese2, T. Cappello2, M. Maisano2 | 1Dept. of Earth and Marine Sciences, University of Palermo, Palermo, Italy; 2Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy
137PDF: 47 -
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells
586PDF: 440Supplementary: 72HTML: 24 -
Immuno- and glyco-histochemistry as a tool to evaluate the oregano supplemented feed effects in pig gut
1864PDF: 885Supplementary: 220HTML: 19 -
P47 | ASSESSMENT OF THE ANTI-INFLAMMATORY AND ANTIFIBROTIC EFFECTS OF HUMAN AMNIOTIC EPITHELIAL CELLS AFTER THEIR INTRATRACHEAL ADMINISTRATION IN A MOUSE MODEL OF BLEOMYCIN-INDUCED PULMONARY FIBROSIS E. Kolanko, A. Mazurski, A. Prusek, E. Bogunia, M. Hermyt, P. Czekaj | Department of Cytophysiology, Medical University of Silesia, Katowice, Poland
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75 | Β-SITOSTEROL-D-GLUCOSIDE TRIGGERS INTESTINAL INFLAMMATION IN ZEBRAFISH LARVAE POSSIBLY LEADING TO NEURODEGENERATION THROUGH THE GUT-BRAIN AXIS Francesca Terrin1, Sofia Faggin2|3, Chiara Consorti4, Stefania Marcotti5, Paolo Bonaldo4, Maria Cecilia Giron2, Nicoletta Plotegher1, Luisa Dalla Valle1 | 1Department of Biology, University of Padova, Italy; 2Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Italy; 3Institute of Digestive Health Research (IRSD), Toulouse University, France; 4Department of Molecular Medicine, University of Padova, Italy; 5Randall Centre for Cell and Molecular Biophysics, King's College London, London; UK
116PDF: 48 -
Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7
1083PDF: 451Supplementary: 65HTML: 56 -
3-hydroxi-anthranilic acid is early expressed in stroke
2402PDF: 753HTML: 315 -
Expression pattern of thymosin beta 4 in the adult human liver
1643PDF: 741HTML: 1414 -
IMMUNOLOGICAL MECHANISMS IN REGENERATIVE MEDICINE: A LESSON FROM THE HUMAN PLACENTA O. Parolini1,2 | 1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy; 2Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
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57 | PUNICA GRANATUM-DERIVED EXTRACELLULAR VESICLES EFFECTS ON AN IN VITRO GASTROINTESTINAL BARRIER MODEL OF INTESTINAL INFLAMMATION Mariano Stefania1, Carata Elisabetta2, Moris Destino2, Bernardetta Anna Tenuzzo2, Panzarini Elisa2 | 1Department of Mathematics and Physics “E. De Giorgi”, University of Salento, Lecce, Italy; 2Department of Biological Sciences and Technologies, University of Salento, Lecce, Italy
79PDF: 87
