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Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1271

PDF: 608

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Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cells via miR-6739-5p modulation and PI3K/AKT pathway activation: a functional histocytochemical study

Zefeng Sun, Xinrong Fan, Zhenquan Liu

02-10-2025

https://doi.org/10.4081/ejh.2025.4253

399

PDF: 357

HTML: 40
Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang

11-05-2023

https://doi.org/10.4081/ejh.2023.3653

1279

PDF: 667

HTML: 41
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He

20-04-2026

https://doi.org/10.4081/ejh.2026.4533

401

PDF: 240

HTML: 13
Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

Nan Li, Xue Fan, Lihong Liu, Yanbing Liu

27-07-2023

https://doi.org/10.4081/ejh.2023.3506

1797

PDF: 1091

HTML: 25
DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu

22-12-2022

https://doi.org/10.4081/ejh.2023.3413

1307

PDF: 653

Supplementary: 109

HTML: 35
Effects of Notch signaling on proliferation, angiogenesis, and adipogenesis of hemangioma-derived stem cells

Weidong Wang, Sheng Chen, Yuan Wang, Cui Jie, Weimin Shen

01-09-2025

https://doi.org/10.4081/ejh.2025.4241

533

PDF: 413

HTML: 11
microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu

10-05-2022

https://doi.org/10.4081/ejh.2022.3333

1834

PDF: 921

HTML: 31
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou

30-06-2025

https://doi.org/10.4081/ejh.2025.4221

974

PDF: 474

HTML: 20
SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang

18-05-2026

https://doi.org/10.4081/ejh.2026.4544

172

PDF: 148

Supplementary: 22

HTML: 7
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang

01-03-2023

https://doi.org/10.4081/ejh.2023.3648

4099

PDF: 1085

HTML: 45
Downregulation of Williams syndrome transcription factor (WSTF) suppresses glioblastoma cell growth and invasion by inhibiting PI3K/AKT signal pathway

Liyuan Yang, Chunfu Du, Hui Chen, Zhengwen Diao

17-11-2021

https://doi.org/10.4081/ejh.2021.3255

1261

PDF: 646

HTML: 49
Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway

Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Han

17-09-2024

https://doi.org/10.4081/ejh.2024.4093

2335

PDF: 612

HTML: 58
Correlation of the AKT/mTOR signaling pathway with the clinicopathological features and prognosis of nasopharyngeal carcinoma

Yan Wang, Jie Sun, Ninghua Yao

16-11-2021

https://doi.org/10.4081/ejh.2021.3304

1717

PDF: 627

HTML: 43
Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin

23-10-2024

https://doi.org/10.4081/ejh.2024.4098

2397

PDF: 498

HTML: 33
miR-19a targeting CLCA4 to regulate the proliferation, migration, and invasion of colorectal cancer cells

Huiwen Li, Bo Huang

10-03-2022

https://doi.org/10.4081/ejh.2022.3381

2123

PDF: 717

HTML: 28
Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study

Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi

31-07-2018

https://doi.org/10.4081/ejh.2018.2956

2000

PDF: 982

Supplementary: 211

HTML: 46
P25 | RESPONSE TO HEDGEHOG AND PI3K/AKT/MTOR PATHWAY INHIBITORS IN PREB-ALL: ANALYSIS OF THE INTRACELLULAR DISTRIBUTION OF PATHWAY ENZYMES AND OF THE AUTOPHAGY PROCESS M. Sicurella¹, M. De Chiara², E. Battaglia², F. Franco², M. De Vita², L.M. Neri² | ¹Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; ²Department of Translational Medicine, University of Ferrara, Ferrara, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4345

201
Significance and relationship between DJ-1 gene and survivin gene expression in laryngeal carcinoma

Z. Shen, Y. Ren, D. Ye, J. Guo, C. Kang, H. Ding

e9

21-03-2011

https://doi.org/10.4081/ejh.2011.e9

1838

PDF: 531

HTML: 1704
Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang

08-09-2023

https://doi.org/10.4081/ejh.2023.3742

1208

PDF: 486

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Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu

15-06-2026

https://doi.org/10.4081/ejh.2026.4569

89

PDF: 80
Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng

17-06-2025

https://doi.org/10.4081/ejh.2025.4218

1443

PDF: 579

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Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

Dajie Wang, Zhaofeng Zhou, Liang Yuan

20-09-2022

https://doi.org/10.4081/ejh.2022.3505

1366

PDF: 611

HTML: 45
The tyrosine kinase receptor c-met, its cognate ligand HGF and the tyrosine kinase receptor trasducers STAT3, PI3K and RHO in thyroid nodules associated with Hashimoto's thyroiditis: an immunohistochemical characterization

R. M. Ruggeri, E. Vitarelli, G. Barresi, F. Trimarchi, S. Benvenga, M. Trovato

e24

03-06-2010

https://doi.org/10.4081/ejh.2010.e24

1483

PDF: 675

HTML: 2606
Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang

17-09-2024

https://doi.org/10.4081/ejh.2024.4034

1224

PDF: 632

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Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou

02-12-2021

https://doi.org/10.4081/ejh.2021.3331

2630

PDF: 1490

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Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

Jun Lin, Liping Jiang, Kun Guo, Ning Feng

22-12-2022

https://doi.org/10.4081/ejh.2023.3528

2048

PDF: 1240

Supplementary: 135

HTML: 39
Knockdown of RAGE inhibits growth and invasion of gastric cancer cells

X.C. Xu, X. Abuduhadeer, W.B. Zhang, T. Li, H. Gao, Y.H. Wang

e36

18-11-2013

https://doi.org/10.4081/ejh.2013.e36

4343

PDF: 850

HTML: 268
Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye

30-09-2021

https://doi.org/10.4081/ejh.2021.3224

3547

PDF: 1912

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Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea

Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong

01-09-2023

https://doi.org/10.4081/ejh.2023.3704

1228

PDF: 968

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Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway

Y. Zhang, J. Wang, X. Cheng, B. Yi, X. Zhang, Q. Li

13-04-2015

https://doi.org/10.4081/ejh.2015.2467

3671

PDF: 1617

HTML: 896
Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation

Yuejuan Cao, Li Cui, Shaoyong Tuo, Hongze Liu, Shaonan Cui

24-04-2024

https://doi.org/10.4081/ejh.2024.4004

1973

PDF: 517

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CAPTURE-CAPIVASERTIB AND PROSTATE CANCER TARGETING: UNRAVELING RESISTANCE ELEMENTS M. Zavatti¹, V. Serafin¹, L. Antolini¹, S. Bresolin², L. Reggiani Bonetti³, S. Marmiroli¹ | ¹Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy; ²Pediatric Hematology, Oncology and Stem Cell Transplant Division, Women and Child Health Department, Padua University, Padua, Italy; ³Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia, Modena, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4277

206
Immunohistochemical expression and clinicopathological assessment of PD-1, PD-L1, NY-ESO-1, and MAGE-A4 expression in highly aggressive soft tissue sarcomas

Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi

22-04-2022

https://doi.org/10.4081/ejh.2022.3393

1359

PDF: 725

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Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway

Zhongzhu Tang, Lei Wang, Yunwang Chen, Xiaomin Zheng, Runyu Wang, Bingxue Liu, Shiqi Zhang, Huimin Wang

07-08-2023

https://doi.org/10.4081/ejh.2023.3719

2085

PDF: 914

HTML: 27
Skeletal muscle cellularity and glycogen distribution in the hypermuscular Compact mice

T. Kocsis, J. BaÃ¡n, G. MÃ¼ller, L. Mendler, L. Dux, A. Keller-PintÃ©r

28-07-2014

https://doi.org/10.4081/ejh.2014.2353

3373

PDF: 706

HTML: 616
E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei

26-05-2025

https://doi.org/10.4081/ejh.2025.4196

1225

PDF: 537

HTML: 20
TRAIL, DR5 and caspase 3-dependent apoptosis in vessels of diseased human temporomandibular joint disc. An immunohistochemical study

C. Loreto, L. E. Almeida, M.R. Migliore, M. Caltabiano, R. Leonardi

e40

13-09-2010

https://doi.org/10.4081/ejh.2010.e40

2674

PDF: 617

HTML: 1614
Inhibition of APLN suppresses cell proliferation and migration and promotes cell apoptosis in esophageal cancer cells in vitro, through activating PI3K/mTOR signaling pathway

Yuhan Wang, Gang Wang, Xiaojun Liu, Dong Yun, Qing Cui, Xiaoting Wu, Wenfeng Lu, Xiwen Yang, Ming Zhang

03-08-2022

https://doi.org/10.4081/ejh.2022.3336

1601

PDF: 772

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SNORA38B promotes proliferation, migration, invasion and epithelial-mesenchymal transition of gallbladder cancer cells via activating TGF-β/Smad2/3 signaling

Yiyu Qin, Jian Li, Hongchao Han, Yongliang Zheng, Haiming Lei, Yang Zhou, Hongyan Wu, Guozhe Zhang, Xiang Chen, Zhengping Chen

28-12-2023

https://doi.org/10.4081/ejh.2023.3899

1149

PDF: 338

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Substance P is overexpressed in cervical squamous cell carcinoma and promoted proliferation and invasion of cervical cancer cells in vitro

Ying Wang, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang

31-07-2023

https://doi.org/10.4081/ejh.2023.3746

1043

PDF: 470

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Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou

22-06-2022

https://doi.org/10.4081/ejh.2022.3394

2030

PDF: 1305

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Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio

e40

04-12-2013

https://doi.org/10.4081/ejh.2013.e40

3779

PDF: 1014

HTML: 633
P37 | THE ROLE OF ACTIN-BINDING PROTEINS IN ENDOMETRIOSIS W. Arendt¹, M. Hałas-Wiśniewska¹, M. Gagat², M. Izdebska¹ | ¹Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; ²Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland

21-08-2025

https://doi.org/10.4081/ejh.2025.4359

201
Effects of cadmium on the glial architecture in lizard brain

Rossana Favorito, Antonio Monaco, Maria C. Grimaldi, Ida Ferrandino

23-01-2017

https://doi.org/10.4081/ejh.2017.2734

3103

PDF: 811

HTML: 369
Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li

22-07-2024

https://doi.org/10.4081/ejh.2024.4048

2412

PDF: 1338

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Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

Rong Tian, Gengsheng Mao

12-01-2022

https://doi.org/10.4081/ejh.2022.3350

1843

PDF: 912

HTML: 41
Molecules involved in the sperm interaction in the human uterine tube: a histochemical and immunohistochemical approach

David Cajas , Emanuel Guajardo, Sergio Jara-Rosales, Claudio Nuñez, Renato Vargas, Victor Carriel, Antonio Campos, Luis Milla, Pedro Orihuela, Carlos Godoy-Guzman

13-04-2023

https://doi.org/10.4081/ejh.2023.3513

1415

PDF: 725

HTML: 42
miR-126 targeting GOLPH3 inhibits the epithelial-mesenchymal transition of gastric cancer BGC-823 cells and reduces cell invasion

Jiancai Ouyang, Fuhu Song, He Li, Rui Yang, Haicheng Huang

28-10-2020

https://doi.org/10.4081/ejh.2020.3168

1496

PDF: 640

HTML: 27
miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen

07-04-2025

https://doi.org/10.4081/ejh.2025.4161

1547

PDF: 482

HTML: 31
64 | UNDERSTANDING PROPERTIES OF NEURAL STEM CELLS ISOLATED FROM A MONOGENIC MOUSE MODEL OF AUTISM EXPRESSING THE R451C NLGN3 MUTATION F. Salvadori, T. Diamanti, L. Santini, S. D’Angelo, F. Serafini, M. Fidaleo, G. Lupo, A. De Jaco, E. Cacci | Department of Biology and Biotechnology “Charles Darwin”, Sapienza University of Rome, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4682

104

PDF: 10
Crocin exerts anti-tumor effect in colon cancer cells via repressing the JAK pathway

Hui Yang, Yunlong Zhang, Desheng Zhang, Liping Qian, Tianxing Yang, Xiaocheng Wu

12-09-2023

https://doi.org/10.4081/ejh.2023.3697

1376

PDF: 664

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Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié

21-08-2025

https://doi.org/10.4081/ejh.2025.4174

620

PDF: 416

HTML: 24
Neurokinin-1 receptor is highly expressed in cervical cancer and its antagonist induces cervical cancer cell apoptosis

Liyun Guan, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang

11-01-2023

https://doi.org/10.4081/ejh.2023.3570

1511

PDF: 702

HTML: 37
Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

16-12-2016

https://doi.org/10.4081/ejh.2016.2711

2644

PDF: 1141

HTML: 311
Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation

Hongkai Xiao, Jinghu Liu, Qinhong Cai, Siyu Liang, Zhitao Hu, Xiaochao Chen

13-10-2025

https://doi.org/10.4081/ejh.2025.4254

708

PDF: 401

HTML: 42
Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li

17-05-2023

https://doi.org/10.4081/ejh.2023.3612

1426

PDF: 930

Supplementary: 100

HTML: 24
Swertiamarin suppresses proliferation, migration, and invasion of hepatocellular carcinoma cells via negative regulation of FRAT1

Shufeng Xiao, Haoren Tang, Yao Bai, Renchao Zou, Zongfang Ren, Xuesong Wu, Zhitian Shi, Song Lan, Wei Liu, Tiangen Wu, Cheng Zhang, Lin Wang

19-10-2020

https://doi.org/10.4081/ejh.2020.3169

1535

PDF: 762

HTML: 34
Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du

05-05-2025

https://doi.org/10.4081/ejh.2025.4178

952

PDF: 404

Supplementary: 52

HTML: 50
MiR-130a-5p contributed to the progression of endothelial cell injury by regulating FAS

Wei Wang, Wenbo Tang, Erbo Shan, Lei Zhang, Shiyuan Chen, Chaowen Yu, Yong Gao

31-05-2022

https://doi.org/10.4081/ejh.2022.3342

1203

PDF: 740

HTML: 31
STAT3 and SOCS3 expression patterns during murine placenta development

S. San Martin, J. Fitzgerald, M. Weber, M. PÃ¡rraga, T. SÃ¡ez, T.M. Zorn, U.R. Markert

e19

28-06-2013

https://doi.org/10.4081/ejh.2013.e19

3700

PDF: 867

HTML: 319
Seasonal expressions of VEGF and its receptors VEGFR1 and VEGFR2 in the prostate of the wild ground squirrels (Spermophilus dauricus)

Yuchen Yao, Wenqian Xie, Di Chen, Yingying Han, Zhengrong Yuan, Haolin Zhang, Qiang Weng

24-03-2021

https://doi.org/10.4081/ejh.2021.3219

1494

PDF: 574

HTML: 48
Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang

01-09-2025

https://doi.org/10.4081/ejh.2025.4217

538

PDF: 218

HTML: 11
miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan

07-12-2021

https://doi.org/10.4081/ejh.2021.3237

1713

PDF: 585

HTML: 27
IncRNA MAPKAPK5-AS1 promotes proliferation and migration of thyroid cancer cell lines by targeting miR-519e-5p/YWHAH

Yan Zhou, Shanshan Liu, Yan Luo, Meiying Zhang, Xueling Jiang, Yan Xiong

03-12-2020

https://doi.org/10.4081/ejh.2020.3177

2230

PDF: 895

HTML: 13
Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

Chixian Zhang, Kai Bai, Dexu Li

14-04-2025

https://doi.org/10.4081/ejh.2025.4186

1325

PDF: 483

HTML: 32
Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells

Yinping Zeng, Jiajun Huang, Tingting Duan, Xiaofeng Wang

28-05-2026

https://doi.org/10.4081/ejh.2026.4540

246

PDF: 185

HTML: 6
Expressions of ZNF436, β-catenin, EGFR, and CMTM5 in breast cancer and their clinical significances

Zhi Chen, Na Cui, Ji-sen Zhao, Jian-fei Wu, Fang Ma, Cong Li, Xian-yi Liu

20-01-2021

https://doi.org/10.4081/ejh.2021.3173

2351

PDF: 827

Supplementary: 188

HTML: 19
Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng

02-10-2023

https://doi.org/10.4081/ejh.2023.3839

1466

PDF: 825

HTML: 40
ANIMAL MODELS OF METASTATIC CANCER - ADVANCED IMAGE ANALYSIS FOR DISSECTION OF DRIVING SIGNALING PATHWAYS S. Alberti | University of Messina, Messina, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4287

183
LncRNA FBXO18-AS promotes gastric cancer progression by TGF-β1/Smad signaling

Yiming Zhang, Wanqiong Zheng, Liang Zhang, Yechun Gu, Lihe Zhu, Yingpeng Huang

20-06-2023

https://doi.org/10.4081/ejh.2023.3667

1241

PDF: 658

Supplementary: 98

HTML: 26
MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9

Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen

12-01-2022

https://doi.org/10.4081/ejh.2022.3275

2070

PDF: 814

Supplementary: 153

HTML: 37
miR-26b regulates cell proliferation and apoptosis of CD117+CD44+ ovarian cancer stem cells by targeting PTEN

Zubiao Gao, Xiaofeng Ye, Anne Bordeaux, Stanka Hettich, Siyao Lin, Fang Han, Yan Jia

04-02-2021

https://doi.org/10.4081/ejh.2021.3186

2338

PDF: 735

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MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells

J. Zhang, J. Luo, J. Ni, L. Tang, H.P. Zhang, L. Zhang, J.F. Xu, D. Zheng

18-02-2014

https://doi.org/10.4081/ejh.2014.2262

3493

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P02 | THE C-C CHEMOKINE-RECEPTOR 2 (CCR2)/CCL2 AXIS PARTICIPATE IN PLATELET FUNCTION IN MYELOFIBROSIS F. Arciprete¹, V. Velardi¹, G. Pozzi², C. Carubbi³, S. Cortellazzi³, A.M. Vannucchi⁴, M. Vitale⁵, R.A. Rana¹, G. Vivacqua¹, E. Masselli³, M. Zingariello¹ | ¹Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; ²Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; ³Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; ⁴Center Research and Innovation of Myeloproliferative Neoplasm, University Hospital Careggi, University of Florence, Florence, Italy; ⁵San Raffaele University, Milano, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4322

230
High glucose inhibits neural differentiation by excessive autophagy via peroxisome proliferator-activated receptor gamma

Yin Pan, Di Qiu, Shu Chen, Xiaoxue Han, Ruiman Li

11-05-2023

https://doi.org/10.4081/ejh.2023.3691

1347

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Expressions of IL-6, TNF-α and NF-κB in the skin of Chinese brown frog (Rana dybowskii)

Liqin Xi, Chen Wang, Pengyu Chen, Qi Yang, Ruiqi Hu, Haolin Zhang, Qiang Weng, Meiyu Xu

19-10-2017

https://doi.org/10.4081/ejh.2017.2834

2477

PDF: 902

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Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui

15-02-2022

https://doi.org/10.4081/ejh.2022.3316

1879

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Tripartite motif-containing protein 6 facilitates growth and migration of breast cancer through degradation of STUB1

Chuanchao Wei, Jiayue Wu, Weiyan Liu, Jingfeng Lu, Hongchang Li, Benjun Hai

10-03-2021

https://doi.org/10.4081/ejh.2021.3214

1781

PDF: 865

Supplementary: 167

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Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei

17-03-2014

https://doi.org/10.4081/ejh.2014.2263

3649

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Umbilical cord mesenchymal stem cells inhibited inflammation of bronchial epithelial cells by regulating Hedgehog pathway

Qiong Lin, Tianxing Yu, Xiaohua Li, Xin Lin, Yong Fan, Liyu Xu

12-12-2023

https://doi.org/10.4081/ejh.2023.3908

1664

PDF: 517

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The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li

25-11-2021

https://doi.org/10.4081/ejh.2021.3323

1955

PDF: 705

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DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu

03-05-2017

https://doi.org/10.4081/ejh.2017.2775

2715

PDF: 1036

HTML: 185
Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats

Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng

12-01-2022

https://doi.org/10.4081/ejh.2022.3328

2285

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HTML: 99
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

26-01-2026

https://doi.org/10.4081/ejh.2026.4422

668

PDF: 390

Supplementary: 52

Original gels: 54

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LncRNA gadd7 promotes mitochondrial membrane potential decrease and apoptosis of alveolar type II epithelial cells by positively regulating MFN1 in an in vitro model of hyperoxia-induced acute lung injury

Guoyue Liu, Cunzhi Yin, Mingjiang Qian, Xuan Xiao, Hang Wu, Fujian Fu

31-05-2023

https://doi.org/10.4081/ejh.2023.3535

1207

PDF: 659

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Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRα) signal through MAPK/ERK pathway in human prostate tissues: a morphological and biomolecular study

Sonia Fantone, Giovanni Tossetta, Rodolfo Montironi, Martina Senzacqua , Daniela Marzioni, Roberta Mazzucchelli

19-10-2020

https://doi.org/10.4081/ejh.2020.3147

2154

PDF: 801

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Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng

21-06-2022

https://doi.org/10.4081/ejh.2022.3412

2550

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