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2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy
3378PDF: 1885Video 1: 344Video 2: 384HTML: 54 -
MITOCHONDRIAL DYSFUNCTION AS A KEY FACTOR OF MOTOR NEURON DEGENERATION: INSIGHTS FROM AMYOTROPHIC LATERAL SCLEROSIS CELLULAR MODELS Scimia N¹, Carletti RM², Rasà MD¹, Ferrari D3, Boido M¹ and Stanga S¹ | ¹Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; ²Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; 3Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
413 -
5XFAD MOUSE MODEL: INVESTIGATING BRAIN IRON IMBALANCE AND MITOCHONDRIAL FEATURES’ ALTERATION Mezzanotte M1, Chicote J1, Scimia N1, Riganti C2, Porporato PE3 and Stanga S1 | 1Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; 2Department of Oncology, Oncological Pharmacology Lab, University of Turin, Italy; 3Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Italy
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06 | OBESITY-INDUCED TESTICULAR DYSFUNCTION: PROTECTIVE ROLES OF THYROID HORMONES IN HIGH-FAT DIET-FED RATS M.R. Ambruosi1, A. Biasi1, M. Vigliotti2, N. Scopigno2, F. Cioffi2, M. Venditti1 | 1Dept. Experimental Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; 2Dept. of Science and Technology, University of Sannio, Benevento, Italy
483PDF: 159 -
P28 | EXPLORING THE POTENTIAL LINK BETWEEN MITOCHONDRIAL DYSFUNCTION AND MITO-EVS IN PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) V. Giansante1, L. Leanza2, E. Guerra3, F. Vianello4, C. Iacovino1, S. Lattanzio1, L. Morello1, G. Stati1, P. Simeone3, P. Lanuti3, S. Alberti5, M. Reichert6, R. Di Pietro1 | 1Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Biology, University of Padua, Padua, Italy; 3Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST)G. d’Annunzio” University of Chieti-Pescara, Italy; 4Department of Biology, University of Padua, Padua, Italy; 5Unit of Medical Genetics, Department of Biomedical Sciences, University of Messina, Messina, Italy; 6Translational Pancreatic Cancer Research Center, Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Center for Organoid Systems (COS), Technical University of Munich, Garching, Germany
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Forever particles: histochemistry in the plasticene age
1688PDF: 794HTML: 106 -
Reliable hexokinase 3 protein detection in human cell lines and primary tissue
2210PDF: 639Supplementary: 127Uncropped Western blots: 114HTML: 57 -
The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis
2066PDF: 1093Supplementary: 260HTML: 60 -
Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis
683PDF: 1095Supplementary: 87HTML: 42 -
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells
722PDF: 659Supplementary: 115HTML: 58 -
SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway
381PDF: 416Supplementary: 90HTML: 41 -
22 | TRANSCRIPTIONAL AND POST-TRANSLATIONAL NETWORKS COORDINATE SELECTIVE AUTOPHAGY TO MAINTAIN ORGANELLE HOMEOSTASIS K. Hartfelt1, M. Petraroia2, T. Persichini2, M. Colasanti2, C. Di Malta3, F. Cecconi4, V. Cianfanelli2 | 1Unit of Cell Stress and Survival, Danish Cancer Institute, Copenhagen, Denmark; 2Dept. of Science, University Roma TRE, Rome, Italy; 3Telethon Institute of Genetics and Medicine, Naples, Italy; 4Dept. of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics Research, Catholic University of the Sacred Heart, Rome, Italy
237PDF: 161 -
P30 | P75NTR MODULATION IMPROVES RESILIENCE TO OXIDATIVE DAMAGE IN A MICROGLIAL CELL MODEL OF PARKINSON’S DISEASE A. Valenza1, D. Pensabene2, F. Rendina1, M. Muzzi2, A. Fracassi3, M. Segatto2, S. Moreno1|3 | 1Dept. of Science, University Roma Tre, Rome, Italy; 2Dept. of Biosciences and Territory, University of Molise, Pesche, Italy; 3Dept. of Neurology, UTMB, Galveston, TX, USA
202PDF: 113 -
GENERATION AND CHARACTERIZATION OF A KNOCK-IN MOUSE MODEL FOR FLVCR1-RELATED SENSORY NEUROPATHY Abalai RE1, Marvaldi L2, Ferrini F3, Riganti C1, Zanin Venturini DI1, Metani L1, Tolosano E1 and Chiabrando D1 | 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center “Guido Tarone”, University of Torino, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Italy; 3Dipartimento di Morfofisiologia Veterinaria and Rita Levi Montalcini Center for Brain Repair, Grugliasco (TO), Italy
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EXPERIMENTAL PARKINSONISM RECRUITS CHOLINERGIC MEDIAL SEPTAL NEURONS Lenzi P1, Lazzeri G1, Ferrucci M1, Scotto M1, Giambelluca MA1, Binda P1 and Fornai F1,2 | 1Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Italy; 2IRCCS, Neuromed, Pozzili, Italy
371 -
27 | CELLULAR AND MOLECULAR MECHANISMS OF GADOLINIUM TOXICITY IN SERTOLI CELLS Sara Falvo1, Giulia Grillo1, Gabriella Chieffi Baccari1, Giuseppe Petito1, Massimo Venditti2, Maria Maddalena Di Fiore1, Tiziana Cappello3, Maria Maisano3, Alessandra Santillo1 | 1Dept of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania L. Vanvitelli, Caserta, Italy; 2Dept of Experimental Medicine, University of Campania L. Vanvitelli, Napoli, Italy; 3Dept of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy
176PDF: 130 -
P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY S. Blando1, E. Boschetti1, I. Neri1, L. Caporali2, C. Fiorini2, D. Ormanbekova2, C. Malagelada3, I. Rusciano1, V. Carelli2, R. De Giorgio4, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Italy; 2IRCCS Institute of Neurological Sciences of Bologna, Neurogenetics Program, Bologna, Italy; 3Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; 4Department of Translational Medicine, University of Ferrara, Ferrara, Italy
270 -
P55 | ENDOTHELIAL THYMIDINE PHOSPHORYLASE DEFICIENCY TRIGGERS MORPHO-FUNCTIONAL DEGE-NERATION OF ENTERIC NEURONS AND REDUCES INTESTINAL STEM CELL PROLIFERATION I. Neri1, E. Boschetti1, T. Saha2, S. Rommel2, S. Schulte2, M. Gries2, R. De Giorgio3, L. Manzoli1, S. Ratti1, K. Schäfer2 | 1Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Workgroup Enteric Nervous System (AGENS), Department of Informatics and Microsystems Technology, University of Applied, Sciences Kaiserslautern, Zweibrücken, Germany; 3Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species
2507PDF: 1437Supplementary: 195HTML: 316
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